Evidence of an association between use of anti-microbial agents in food animals and anti-microbial resistance among bacteria isolated from humans and the human health consequences of such resistance

Journal of Veterinary Medicine Series B: Infectious Diseases and Veterinary Public Health

Volumn 51, Issue 8-9, 2004, Pages 374-379

  Angulo, F J ^a   Nargund, V N ^a   Chiller, T C ^a  

^a NATL CENTER FOR INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; VETERINARY DRUG;

ANIMAL; ANTIBIOTIC RESISTANCE; CAMPYLOBACTER; CONFERENCE PAPER; DRUG EFFECT; DRUG UTILIZATION; ESCHERICHIA COLI; FOOD CONTROL; GENETICS; HUMAN; MEAT; MICROBIOLOGY; SALMONELLA;

ANIMALS; ANTI-BACTERIAL AGENTS; CAMPYLOBACTER; DRUG RESISTANCE, BACTERIAL; DRUG UTILIZATION; ESCHERICHIA COLI; FOOD MICROBIOLOGY; HUMANS; MEAT; SALMONELLA; VETERINARY DRUGS;

ANIMALIA; BACTERIA (MICROORGANISMS); CAMPYLOBACTER; ENTEROCOCCUS; ESCHERICHIA COLI; SALMONELLA;

EID: 9244242625     PISSN: 09311793     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1439-0450.2004.00789.x     Document Type: Conference Paper

References (38)

1. Aarestrup, F. M., C. Wiuff, K. Mølbak, and E. J. Threlfall, 2003: Is it time to change fluoroquinolone breakpoints for Salmonella spp. Antimicrob. Agents Chemother. 47, 827-829.
2. Angulo, F. J., K. R. Johnson, R. V. Tauxe, and M. L. Cohen, 2000: Origins and consequences of antimicrobial-resistant nontyphoidal Salmonella: implications for the use of fluoroquinolones in food animals. Microb. Drug Resist. 6, 77-83.
3. Barza, M., 2002: Potential mechanisms of increased disease in humans from antimicrobial resistance in food animals. Clin. Infect. Dis. 34, S123-S125.
4. Barza, M., and K. Travers, 2002: Excess infections due to antimicrobial resistance: the 'attributable fraction'. Clin. Infect. Dis. 34, S126-S130.
5. Bohnhoff, M., and C. P. Miller, 1962: Enhanced susceptibility to Salmonella infection in streptomycin-treated mice. J. Infect. Dis. 111, 117-127.
6. Bruinsma, N., R. J. Willems, A. E. van den Bogaard, M. van Santen-Verheuvel, N. London, C. Driessen, and E. E. Stobberingh, 2002: Different levels of genetic homogeneity in vancomycin-resistant and -susceptible Enterococcus faecium isolates from different human and animal sources analyzed by amplified-fragment length polymorphism. Antimicrob. Agents Chemother. 46, 2279-2283.
7. Chiu, C. H., T. L. Wu, L. H. Su, C. Chishih, C. Ju-Hsin, K. An-Jing, C. Maw-Sheng, and L. Tzou-Yien, 2002: The emergence in Taiwan of fluoroquinolone resistance in Salmonella enterica serotype Choleraesuis. N. Engl. J. Med. 346, 413-419.
8. Codex Committee on Food Hygiene, 2001: Discussion of a Comprehensive Multidisciplinary Approach to Risk Assessment on Anti-microbial Resistant Bacteria in Food, 34th Session, 8-13 October. FAO/WHO/WTO, Bangkok, Thailand.
9. Codex Committee on Residues of Veterinary Drugs in Foods, 2001: Discussion Paper on Antimicrobial Resistance and the Use of Antimicrobials in Animal Production, 13th Session, 4-7 December. CX/RVDF 01/10. Joint FAO/WHO Food Standards Programme, Charleston, SC.
10. Crump, J. A., T. J. Barrett, J. T. Nelson, and F. J. Angulo, 2003: Reevaluating fluoroquinolone breakpoints for Salmonella enterica serotype Typhi and for non-Typhi Salmonella. Clin. Infect. Dis. 37, 75-81.
11. DANMAP, 2002: Use of Antimicrobial Agents and Occurrence of Antimicrobial Resistance in Bacteria from Food Animals, Foods and Humans in Denmark. Available at http://www.dfvf.dk/Files/Filer/Zoonosecentret/Publikationer/Danmap/ Danmap_2002.pdf, accessed 13 October 2004.
12. Donabedian, S. M., L. A. Thal, E. Hershberger, M. B. Perri, J. W. Chow, P. Bartlett, R. Jones, K. Joyce, S. Rossiter, K. Gay, J. Johnson, C. Mackinson, E. Debess, J. Madden, F. Angulo, and M. J. Zervos, 2003: Molecular characterization of gentamicin-resistant Enterococci in the United States: evidence of spread from animals to humans through food. J. Clin. Microbiol. 41, 1109-1113.
13. Endtz, H. P., R. P. Mouton, T. van der Reyden, G. J. Ruijs, M. Biever, and B. van Klingeren, 1990: Fluoroquinolone resistance in Campylobacter spp. isolated from human stools and poultry products. Lancet 335, 787.
14. Engberg, J., J. Neimann, E. M. Nielsen, F. M. Aarestrup, and V. Fussing, 2004: Quinolone-resistant Campylobacter infections: risk factors and clinical consequences. Emerg. Infect. Dis. 10, 1056-1063.
15. Fey, P., T. Safranek, M. Rupp, E. F. Dunne, E. Ribot, P. C. Iwen, P. A. Bradford, F. J. Angulo, and S. H. Hinrichs, 2000: Ceftriaxone-resistant Salmonella infection acquired by a child from cattle. N. Engl. J. Med. 342, 1242-1249.
16. Glynn, M. K., V. Reddy, L. Hutwagner, T. Rabatsky-Ehr, B. Shiferaw, D. J. Vugia, S. Segler, J. Bender, T. J. Barrett, F. J. Angulo, and Emerging Infections Program FoodNet Working Group, 2004: Prior antimicrobial agent use increases the risk of sporadic infections with multidrug-resistant Salmonella enterica serotype Typhimurium: a FoodNet case-control study. Clin. Infect. Dis. 38, S227-S236.
17. Gupta, A., J. Fontana, C. Crowe, B. Balstorff, A. Stout, S. VanDuyne, M. P. Hoekstra, J. M. Whichard, T. J. Barrett, and F. J. Angulo, 2003: Emergence of multidrug-resistant Salmonella enterica serotype Newport infections resistant to expanded-spectrum cephalosporins in the United States. J. Infect. Dis. 188, 1707-1716.
18. Helms, M., P. Vastrup, P. Gerner-Smidt, and K. Mølbak, 2002: Excess mortality associated with antimicrobial drug-resistant Salmonella Typhimurium. Emerg. Infect. Dis. 8, 490-495.
19. Helms, M., J. Simonsen, K. E. P. Olsen, and K. Mølbak, 2004: Adverse health effects associated with antimicrobial drug resistance in Campylobacter spp.: a registry-based study. J. Infect. Dis. (in press).
20. Holmberg, S. D., S. L. Solomon, and P. A. Blake, 1987: Health and economic impacts of antimicrobial resistance. Rev. Infect. Dis. 9, 1065-1078.
21. Hummel, R., H. Tschape, and W. Witte, 1986: Spread of plasmid-mediated nourseothricin resistance due to antibiotic use in animal husbandry. J. Basic Microbiol. 26, 461-466.
22. Jensen, L. B., P. Ahrens, L. Dons, R. N. Jones, A. M. Hammerum, and F.M. Aarestrup, 1998: Molecular analysis of Tn1546 in Enterococcus faecium isolated from animals and humans. J. Clin. Microbiol. 36, 437-442.
23. Kassenborg, H. D., K. E. Smith, D. J. Vugia, T. Rabatsky-Ehr, M. R. Bates, M. A. Carter, N. B. Dumas, M. P. Cassidy, N. Marano, R. V. Tauxe, F. J. Angulo, and Emerging Infections Program FoodNet Working Group, 2004: Fluoroquinolone-resistant Campylobacter infections: Eating poultry outside the home and foreign travel are risk factors. Clin. Infect. Dis. 38, S279-S284.
24. Lee, L. A., N. D. Puhr, E. K. Maloney, N. H. Bean, and R. V. Tauxe, 1994: Increase in antimicrobial-resistant Salmonella infections in the United States, 1989-1990. J. Infect. Dis. 170, 128-134.
25. Levy, S., G. Fitzerald, and A. Macone, 1976: Changes in intestinal flora of farm personnel after introduction of a tetracycline-supplemented feed on a farm. N. Eng. J. Med. 295, 583-588.
26. Mølbak, K., D. L. Baggesen, F. M. Aarestrup, J. M. Ebbesen, J. Engberg, K. Frydendahl, P. Gerner-Smidt, A. M. Petersen, and H. Wegener, 1999: An outbreak of multi-drug resistant, quinolone-resistant Salmonella enterica serotype Typhimurium DT104. N. Engl. J. Med. 341, 1420-1425.
27. Neimann, J., J. Engberg, K. Mølbak, and H. C. Wegener, 2003: A case-control study of risk factors for sporadic C ampylobacter infections in Denmark. Epidemiol. Infect. 130, 353-366.
28. Nelson, J., and F. Angulo, 2004: Fluoroquinolone-resistant Campylobacter causes longer duration of diarrhea than fluoroquinolone-susceptible Campylobacter strains in FoodNet sites. J. Infect. Dis. 190, 1150-1157.
29. Smith, K. E., J. M. Besser, C. W. Hedberg, F. T. Leano, J. B. Bender, J. H. Wicklund, B. P. Johnson, K. A. Moore, and M. T. Osterholm, 1999: Quinolone-resistant Campylobacter jejuni infections in Minnesota, 1992-1998. N. Engl. J. Med. 340, 1525-1532.
30. Spika, J., S. Waterman, G. Hoo, M. E. St. Louis, R. E. Pacer, S. M. James, M. L. Bissett, L. W. Mayer, J. Y. Chiu, and B. Hall, 1987: Chloramphenicol-resistant Salmonella Newport traced through hamburger to dairy farms: a major persisting source of human salmonellosis in California. N. Engl. J. Med. 316, 565-570.
31. Swann, M. M., Blaxter, K. L., Field, H. I., Howie, J. W., Lucas, A. M., Millar, E. L. M., Murdoch, J. C., Parsons, J. H., and White, E. G., 1968: Joint Committee on the Use of Antibiotics in Animal Husbandry and Veterinary Medicine. Her Majesty's Stationery Office, London.
32. Swartz, M. N., 2002: Human diseases caused by foodborne pathogens of animal origin. Clin. Infect. Dis. 34, S111-S122.
33. Unicomb, L., J. Ferguson, T. V. Riley, and P. Collignon, 2003: Fluoroquinolone resistance in Campylobacter absent from isolates, Australia. Emerg. Infect. Dis. 9, 1482-1483.
34. Varma, J. K., K. Mølbak, T. J. Barrett, J. L. Beebe, T. F. Jones, T. Rabatsky-Ehr, K. E. Smith, D. J. Bugia, H. H. Chang, and F. J. Angulo, 2004: Antimicrobial-resistant nonyphoidal Salmonella is associated with excess bloodstream infections and hospitalizations. J. Infect. Dis. (in press).
35. Walker, R. A., A. J. Lawson, E. A. Lindsay, L. R. Ward, P. A. Wright, F. J. Bolton, D. R. A. Wareing, J. D. Corkish, R. H. Davies, and E. J. Threlfall, 2000: Decreased susceptibility to ciprofloxacin in outbreak-associated multiresistant Salmonella typhimurium DT104. Vet. Rec. 147, 395-396.
36. Witte, W., H. Tschape, I. Klare, and G. Werner, 2000: Antibiotics in animal feed. Acta Veterinary Scandanavia 93, 37-45.
37. World Health Organization (WHO), 1997. The Medical Impact of the Use of Antimicrobials in Food Animals. Report of a WHO Meeting, Berlin, Germany, 13-17 October 1997. WHO, Geneva, Switzerland.
38. World Health Organization (WHO), 1998. Use of Quinolones in Food Animals and Potential Impact on Human Health. Report of a WHO meeting, Geneva, Switzerland, 2-5 June 1998. WHO, Geneva, Switzerland.