Development and cancer: Two sides of the same coin

International Congress Series

Volumn 1296, Issue , 2006, Pages 147-159

  Vidal, Anxo ^a,b   Capellini, Terence D ^c,d   Yeh, Nancy ^b   Selleri, Licia ^d   Koff, Andrew ^b   Bromage, Timothy G ^e  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c CITY UNIVERSITY OF NEW YORK   (United States)

^d WEILL CORNELL MEDICAL CENTER   (United States)

^e NEW YORK UNIVERSITY COLLEGE OF DENTISTRY   (United States)

Author keywords

Bone; Cancer; Cell cycle; Development; Knockout mouse

Indexed keywords

EID: 33745142186     PISSN: 05315131     EISSN: None     Source Type: Book Series    
DOI: 10.1016/j.ics.2006.03.033     Document Type: Article

References (28)

1. Karsenty G., and Wagner E.F. Reaching a genetic and molecular understanding of skeletal development. Dev Cell 2 (2002) 389-406
2. Malumbres M., and Barbacid M. To cycle or not to cycle: a critical decision in cancer. Nat Rev Cancer 1 (2001) 222-231
3. Dyson N. The regulation of E2F by pRB-family proteins. Genes Dev 12 (1998) 2245-2262
4. Ren B., Cam H., Takahashi Y., Volkert T., Terragni J., Young R.A., et al. E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints. Genes Dev 16 (2002) 245-256
5. Sherr C.J., and Roberts J.M. CDK inhibitors: positive and negative regulators of G(1)-phase progression. Genes Dev 13 (1999) 1501-1512
6. Vidal A., and Koff A. Cell-cycle inhibitors: three families united by a common cause. Gene 247 (2000) 1-15
7. Wagner E.F., and Karsenty G. Genetic control of skeletal development. Curr Opin Genet Dev 11 (2001) 527-532
8. Cobrinik D., Lee M.H., Hannon G., Mulligan G., Bronson R.T., Dyson N., et al. Shared role of the pRB-related p130 and p107 proteins in limb development. Genes Dev 10 (1996) 1633-1644
9. Rossi F., MacLean H.E., Yuan W., Francis R.O., Semenova E., Lin C.S., et al. p107 and p130 coordinately regulate proliferation, Cbfa1 expression, and hypertrophic differentiation during endochondral bone development. Dev Biol 247 (2002) 271-285
10. Yan Y.M., Lee M.H., Massague J., and Barbacid M. Ablation of the CDK inhibitor p57(Kip2) results in increased apoptosis and delayed differentiation during mouse development. Genes Dev 11 (1997) 973-983
11. Zhang P.M., Liegeois N.J., Wong C., Finegold M., Hou H., Thompson J.C., et al. Altered cell differentiation and proliferation in mice lacking p57(KIP2) indicates a role in Beckwith-Wiedemann syndrome. Nature 387 (1997) 151-158
12. Chen C.R., Kang Y.B., Siegel P.M., and Massague J. E2F4/5 and p107 as Smad cofactors linking the TGF beta receptor to c-myc repression. Cell 110 (2002) 19-32
13. Ohnuma S., Philpott A., Wang K., Holt C.E., and Harris W.A. p27(Xic1), a cdk inhibitor, promotes the determination of glial cells in Xenopus retina. Cell 99 (1999) 499-510
14. Vernon A.E., and Philpott A. A single cdk inhibitor, p27(xic1), functions beyond cell cycle regulation to promote muscle differentiation in Xenopus. Development 130 (2003) 71-83
15. Zezula J., Casaccia-Bonnefil P., Ezhevsky S.A., Osterhout D.J., Levine J.M., Dowdy S.F., et al. p21(cip1) is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal. Embo Rep 2 (2001) 27-34
16. Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 (2000) 57-70
17. Leroi A.M., Koufopanou V., and Burt A. Cancer selection. Nat Rev Cancer 3 (2003) 226-231
18. Ezzati M., Lopez A.D., Rodgers A., Vander Hoorn S., and Murray C.J.L. Selected major risk factors and global and regional burden of disease. Lancet 360 (2002) 1347-1360
19. Stein C.J., and Colditz G.A. Modifiable risk factors for cancer. Br J Cancer 90 (2004) 299-303
20. Demant P. Cancer susceptibility in the mouse: genetics, biology and implications for human cancer. Nat Rev Genet 4 (2003) 721-734
21. Peto J., and Mack T.M. High constant incidence in twins and other relatives of women with breast cancer. Nat Genet 26 (2000) 411-414
22. Pharoah P.D.P., Antoniou A., Bobrow M., Zimmern R.L., Easton D.F., and Ponder B.A.J. Polygenic susceptibility to breast cancer and implications for prevention. Nat Genet 31 (2002) 33-36
23. Gutierrez C., Ramirez-Parra E., Castellano M.M., and del Pozo J.C. G(1) to S transition: more than a cell cycle engine switch. Curr Opin Plant Biol 5 (2002) 480-486
24. Krylov D.M., Nasmyth K., and Koonin E.V. Evolution of eukaryotic cell cycle regulation: stepwise addition of regulatory kinases and late advent of the CDKs. Curr Biol 13 (2003) 173-177
25. Galis F. Why do almost all mammals have seven cervical vertebrae? developmental constraints, Hox genes, and cancer. J Exp Zool 285 (1999) 19-26
26. Galis F., and Metz J.A.J. Anti-cancer selection as a source of developmental and evolutionary constraints. Bioessays 25 (2003) 1035-1039
27. Kavanagh K.D. Embedded molecular switches, anticancer selection, and effects on ontogenetic rates: a hypothesis of developmental constraint on morphogenesis and evolution. Evolution 57 (2003) 939-948
28. Tamura K., et al. Mechanism of carcinogenesis in familial tumors. Int J Clin Oncol 9 (2004) 232-245