메뉴 건너뛰기




Volumn 11, Issue 5, 2006, Pages 659-661

p53 and Retinoblastoma protein (pRb): A complex network of interactions

Author keywords

Apoptosis; Cell cycle; p53; pRb

Indexed keywords

PROTEIN P53; RETINOBLASTOMA PROTEIN;

EID: 33745026748     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-006-5543-y     Document Type: Article
Times cited : (20)

References (37)
  • 1
    • 0033590071 scopus 로고    scopus 로고
    • The retinoblastoma gene family in differentiation and development
    • Lipinski MM, Jacks T. The retinoblastoma gene family in differentiation and development. Oncogene 1999; 18: 7873-7882.
    • (1999) Oncogene , vol.18 , pp. 7873-7882
    • Lipinski, M.M.1    Jacks, T.2
  • 2
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg RA. The retinoblastoma protein and cell cycle control. Cell 1995; 81: 323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 3
    • 0035835815 scopus 로고    scopus 로고
    • The retinoblastoma gene: A prototypic and multifunctional tumor suppressor
    • Zheng L, Lee WH. The retinoblastoma gene: A prototypic and multifunctional tumor suppressor. Exp Cell Res 2001; 264: 2-18.
    • (2001) Exp Cell Res , vol.264 , pp. 2-18
    • Zheng, L.1    Lee, W.H.2
  • 4
    • 0033786378 scopus 로고    scopus 로고
    • Rb function in cell-cycle regulation and apoptosis
    • Harbour JW, Dean DC. Rb function in cell-cycle regulation and apoptosis. Nat Cell Biol 2000; 2: E65-E67.
    • (2000) Nat Cell Biol , vol.2
    • Harbour, J.W.1    Dean, D.C.2
  • 5
    • 0033040967 scopus 로고    scopus 로고
    • pRb and E2f-1 in mouse development and tumorigenesis
    • Macleod K. pRb and E2f-1 in mouse development and tumorigenesis. Curr Opin Genet Dev 1999; 9: 31-39.
    • (1999) Curr Opin Genet Dev , vol.9 , pp. 31-39
    • Macleod, K.1
  • 6
    • 23844514818 scopus 로고    scopus 로고
    • Cell cycle-dependent nuclear retention of p53 by E2F1 requires phosphorylation of p53 at Ser315
    • Fogal V, Hsieh JK, Royer C, Zhong S, Lu X. Cell cycle-dependent nuclear retention of p53 by E2F1 requires phosphorylation of p53 at Ser315. Embo J 2005; 24: 2768-2782.
    • (2005) Embo J , vol.24 , pp. 2768-2782
    • Fogal, V.1    Hsieh, J.K.2    Royer, C.3    Zhong, S.4    Lu, X.5
  • 7
    • 0036132647 scopus 로고    scopus 로고
    • Novel function of the cyclin A binding site of E2F in regulating p53-induced apoptosis in response to DNA damage
    • Hsieh JK, Yap D, O'Connor DJ, et al. Novel function of the cyclin A binding site of E2F in regulating p53-induced apoptosis in response to DNA damage. Mol Cell Biol 2002; 22: 78-93.
    • (2002) Mol Cell Biol , vol.22 , pp. 78-93
    • Hsieh, J.K.1    Yap, D.2    O'Connor, D.J.3
  • 8
    • 0028222124 scopus 로고
    • p53 and E2F-1 cooperate to mediate apoptosis
    • Wu XW, Levine AJ. p53 and E2F-1 cooperate to mediate apoptosis. Proc Natl Acad Sci USA 1994; 91: 3602-3606.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3602-3606
    • Wu, X.W.1    Levine, A.J.2
  • 9
    • 0032475878 scopus 로고    scopus 로고
    • Signaling top53: Breaking the MDM2-p53 circuit
    • Prives C. Signaling top53: Breaking the MDM2-p53 circuit. Cell 1998; 95: 5-8.
    • (1998) Cell , vol.95 , pp. 5-8
    • Prives, C.1
  • 10
    • 17144371342 scopus 로고    scopus 로고
    • Novel link between E2F and p53: Proapoptotic cofactors of p53 are transcriptionally upregulated by E2F
    • Hershko T, Chaussepied M, Oren M, Ginsberg D. Novel link between E2F and p53: Proapoptotic cofactors of p53 are transcriptionally upregulated by E2F. Cell Death Differ 2005; 12: 377-383.
    • (2005) Cell Death Differ , vol.12 , pp. 377-383
    • Hershko, T.1    Chaussepied, M.2    Oren, M.3    Ginsberg, D.4
  • 11
    • 0036841678 scopus 로고    scopus 로고
    • The retinoblastoma protein binds the promoter of the survival gene bcl-2 and regulates its transcription in epithelial cells through transcription factor AP-2
    • Decary S, Decesse JT, Ogryzko V, et al. The retinoblastoma protein binds the promoter of the survival gene bcl-2 and regulates its transcription in epithelial cells through transcription factor AP-2. Mol Cell Biol 2002; 22: 7877-7888.
    • (2002) Mol Cell Biol , vol.22 , pp. 7877-7888
    • Decary, S.1    Decesse, J.T.2    Ogryzko, V.3
  • 12
    • 0035796491 scopus 로고    scopus 로고
    • Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system
    • Lipinski MM, Macleod KF, Williams BO, et al. Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system. Embo J 2001; 20: 3402-3413.
    • (2001) Embo J , vol.20 , pp. 3402-3413
    • Lipinski, M.M.1    Macleod, K.F.2    Williams, B.O.3
  • 13
    • 0028999429 scopus 로고
    • p53-mediated apoptosis in HeLa cells can be overcome by excess pRb
    • Haupt Y, Rowan S, Oren M. p53-mediated apoptosis in HeLa cells can be overcome by excess pRb. Oncogene 1995; 10: 1562-1571.
    • (1995) Oncogene , vol.10 , pp. 1562-1571
    • Haupt, Y.1    Rowan, S.2    Oren, M.3
  • 14
    • 0033778289 scopus 로고    scopus 로고
    • Retinoblastoma protein-initiated cellular growth arrest overcomes the ability of cotransfected wild-type p53 to induce apoptosis
    • Shinohara H, Zhou J, Yoshikawa K, et al. Retinoblastoma protein-initiated cellular growth arrest overcomes the ability of cotransfected wild-type p53 to induce apoptosis. Br J Cancer 2000; 83: 1039-1046.
    • (2000) Br J Cancer , vol.83 , pp. 1039-1046
    • Shinohara, H.1    Zhou, J.2    Yoshikawa, K.3
  • 15
    • 0028231023 scopus 로고
    • Identification of a p53 binding site in the human retinoblastoma susceptibility gene promoter
    • Osifchin NE, Jiang D, Ohtani-Fujita N, et al. Identification of a p53 binding site in the human retinoblastoma susceptibility gene promoter. J Biol Chem 1994; 269: 6383-6389.
    • (1994) J Biol Chem , vol.269 , pp. 6383-6389
    • Osifchin, N.E.1    Jiang, D.2    Ohtani-Fujita, N.3
  • 16
    • 0034638841 scopus 로고    scopus 로고
    • p53 regulates myogenesis by triggering the differentiation activity of pRb
    • Porrello A, Cerone MA, Coen S, et al. p53 regulates myogenesis by triggering the differentiation activity of pRb. J Cell Biol 2000; 151: 1295-1304.
    • (2000) J Cell Biol , vol.151 , pp. 1295-1304
    • Porrello, A.1    Cerone, M.A.2    Coen, S.3
  • 17
    • 0033230581 scopus 로고    scopus 로고
    • The cellular response to p53: The decision between life and death
    • Sionov RV, Haupt Y. The cellular response to p53: The decision between life and death. Oncogene 1999; 18: 6145-6157.
    • (1999) Oncogene , vol.18 , pp. 6145-6157
    • Sionov, R.V.1    Haupt, Y.2
  • 18
    • 0027934570 scopus 로고
    • p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    • Morgenbesser SD, Williams BO, Jacks T, DePinho RA. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 1994; 371: 72-74.
    • (1994) Nature , vol.371 , pp. 72-74
    • Morgenbesser, S.D.1    Williams, B.O.2    Jacks, T.3    DePinho, R.A.4
  • 19
    • 0028169994 scopus 로고
    • p53-dependent apoptosis suppresses tumor growth and progression in vivo
    • Symonds H, Krall L, Remington L, et al. p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell 1994; 78: 703-711.
    • (1994) Cell , vol.78 , pp. 703-711
    • Symonds, H.1    Krall, L.2    Remington, L.3
  • 20
    • 0035035730 scopus 로고    scopus 로고
    • RB activation and repression of C-MYC transcription precede apoptosis of human prostate epithelial cells
    • Zhao X, Day ML. RB activation and repression of C-MYC transcription precede apoptosis of human prostate epithelial cells. Urology 2001; 57: 860-865.
    • (2001) Urology , vol.57 , pp. 860-865
    • Zhao, X.1    Day, M.L.2
  • 21
    • 0347721777 scopus 로고    scopus 로고
    • Retinoblastoma protein-mediated apoptosis after gamma-irradiation
    • Bowen C, Birrer M, Gelmann EP. Retinoblastoma protein-mediated apoptosis after gamma-irradiation. J Biol Chem 2002; 277: 44969-44979.
    • (2002) J Biol Chem , vol.277 , pp. 44969-44979
    • Bowen, C.1    Birrer, M.2    Gelmann, E.P.3
  • 22
    • 0032146778 scopus 로고    scopus 로고
    • Radiation-induced apoptosis mediated by retinoblastoma protein
    • Bowen C, Spiegel S, Gelmann EP. Radiation-induced apoptosis mediated by retinoblastoma protein. Cancer Res 1998; 58: 3275-3281.
    • (1998) Cancer Res , vol.58 , pp. 3275-3281
    • Bowen, C.1    Spiegel, S.2    Gelmann, E.P.3
  • 23
    • 0030988914 scopus 로고    scopus 로고
    • Cell anchorage regulates apoptosis through the retinoblastoma tumor suppressor/E2F pathway
    • Day ML, Foster RG, Day KC, et al. Cell anchorage regulates apoptosis through the retinoblastoma tumor suppressor/E2F pathway. J Biol Chem 1997; 272: 8125-8128.
    • (1997) J Biol Chem , vol.272 , pp. 8125-8128
    • Day, M.L.1    Foster, R.G.2    Day, K.C.3
  • 24
    • 0033575960 scopus 로고    scopus 로고
    • The retinoblastoma tumor suppressor inhibits cellular proliferation through two distinct mechanisms: Inhibition of cell cycle progression and induction of cell death
    • Knudsen KE, Weber E, Arden KC, et al. The retinoblastoma tumor suppressor inhibits cellular proliferation through two distinct mechanisms: Inhibition of cell cycle progression and induction of cell death. Oncogene 1999; 18: 5239-5245.
    • (1999) Oncogene , vol.18 , pp. 5239-5245
    • Knudsen, K.E.1    Weber, E.2    Arden, K.C.3
  • 25
    • 0033082231 scopus 로고    scopus 로고
    • RB regulates the stability and the apoptotic function of p53 via MDM2
    • Hsieh JK, Chan FS, O'Connor DJ, et al. RB regulates the stability and the apoptotic function of p53 via MDM2. Mol Cell 1999; 3: 181-193.
    • (1999) Mol Cell , vol.3 , pp. 181-193
    • Hsieh, J.K.1    Chan, F.S.2    O'Connor, D.J.3
  • 26
    • 0030827081 scopus 로고    scopus 로고
    • Deletion of RB exons 24 and 25 causes low-penetrance retinoblastoma
    • Bremner R, Du DC, Connolly-Wilson MJ, et al. Deletion of RB exons 24 and 25 causes low-penetrance retinoblastoma. Am J Hum Genet 1997; 61: 556-570.
    • (1997) Am J Hum Genet , vol.61 , pp. 556-570
    • Bremner, R.1    Du, D.C.2    Connolly-Wilson, M.J.3
  • 28
    • 0030999788 scopus 로고    scopus 로고
    • Apoptosis is associated with cleavage of a 5 kDa fragment from RB which mimics dephosphorylation and modulates E2F binding
    • Chen WD, Otterson GA, Lipkowitz S, et al. Apoptosis is associated with cleavage of a 5 kDa fragment from RB which mimics dephosphorylation and modulates E2F binding. Oncogene 1997; 14: 1243-1248.
    • (1997) Oncogene , vol.14 , pp. 1243-1248
    • Chen, W.D.1    Otterson, G.A.2    Lipkowitz, S.3
  • 29
    • 0034720190 scopus 로고    scopus 로고
    • Caspase-dependent cleavage of the retinoblastoma protein is an early step in neuronal apoptosis
    • Boutillier AL, Trinh E, Loeffler JP. Caspase-dependent cleavage of the retinoblastoma protein is an early step in neuronal apoptosis. Oncogene 2000; 19: 2171-2178.
    • (2000) Oncogene , vol.19 , pp. 2171-2178
    • Boutillier, A.L.1    Trinh, E.2    Loeffler, J.P.3
  • 30
    • 0030462563 scopus 로고    scopus 로고
    • Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis
    • Janicke RU, Walker PA, Lin XY, Porter AG. Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis. Embo J 1996; 15: 6969-6978.
    • (1996) Embo J , vol.15 , pp. 6969-6978
    • Janicke, R.U.1    Walker, P.A.2    Lin, X.Y.3    Porter, A.G.4
  • 31
    • 0035942496 scopus 로고    scopus 로고
    • Sequential two-step cleavage of the retinoblastoma protein by caspase-3/-7 during etoposide-induced apoptosis
    • Fattman CL, Delach SM, Dou QP, Johnson DE. Sequential two-step cleavage of the retinoblastoma protein by caspase-3/-7 during etoposide-induced apoptosis. Oncogene 2001; 20: 2918-2926.
    • (2001) Oncogene , vol.20 , pp. 2918-2926
    • Fattman, C.L.1    Delach, S.M.2    Dou, Q.P.3    Johnson, D.E.4
  • 32
    • 0036800351 scopus 로고    scopus 로고
    • Signal-dependent protection from apoptosis in mice expressing caspase-resistant Rb
    • Chau BN, Borges HL, Chen TT, et al. Signal-dependent protection from apoptosis in mice expressing caspase-resistant Rb. Nat Cell Biol 2002; 4: 757-765.
    • (2002) Nat Cell Biol , vol.4 , pp. 757-765
    • Chau, B.N.1    Borges, H.L.2    Chen, T.T.3
  • 33
    • 0032127463 scopus 로고    scopus 로고
    • p53 facilitates pRb cleavage in IL-3-deprived cells: Novel pro-apoptotic activity of p53
    • Gottlieb E, Oren M. p53 facilitates pRb cleavage in IL-3-deprived cells: Novel pro-apoptotic activity of p53. Embo J 1998; 17: 3587-3596.
    • (1998) Embo J , vol.17 , pp. 3587-3596
    • Gottlieb, E.1    Oren, M.2
  • 34
    • 22244471087 scopus 로고    scopus 로고
    • Gankyrin: An intriguing name for a novel regulator of p53 and RB
    • Lozano G, Zambetti GP. Gankyrin: An intriguing name for a novel regulator of p53 and RB. Cancer Cell 2005; 8: 3-4.
    • (2005) Cancer Cell , vol.8 , pp. 3-4
    • Lozano, G.1    Zambetti, G.P.2
  • 35
    • 19944431662 scopus 로고    scopus 로고
    • Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation
    • Uchida C, Miwa S, Kitagawa K, et al. Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation. Embo J 2005; 24: 160-169.
    • (2005) Embo J , vol.24 , pp. 160-169
    • Uchida, C.1    Miwa, S.2    Kitagawa, K.3
  • 36
    • 0038190875 scopus 로고    scopus 로고
    • Inactivation of retinoblastoma (RB) tumor suppressor by oncogenic isoforms of the p53 family member p73
    • Stiewe T, Stanelle J, Theseling CC, et al. Inactivation of retinoblastoma (RB) tumor suppressor by oncogenic isoforms of the p53 family member p73. J Biol Chem 2003; 278: 14230-14236.
    • (2003) J Biol Chem , vol.278 , pp. 14230-14236
    • Stiewe, T.1    Stanelle, J.2    Theseling, C.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.