HOXB4-induced self-renewal of hematopoietic stem cells is significantly enhanced by p21 deficiency

Stem Cells

Volumn 24, Issue 3, 2006, Pages 653-661

  Miyake, Noriko ^a   Brun, Ann C M ^a   Magnusson, Mattias ^a   Miyake, Koichi ^a   Scadden, David T ^b   Karlsson, Stefan ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Hematopoiesis; HOXB4 p21; Stem cell expansion

Indexed keywords

GREEN FLUORESCENT PROTEIN; HOX PROTEIN; PROTEIN P21; RETROVIRUS VECTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HOXB4; UNCLASSIFIED DRUG; CDKN1A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; HOMEODOMAIN PROTEIN; HOXB4 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL POPULATION; CELL PROLIFERATION; CELL RENEWAL; COLONY FORMING UNIT; CONTROLLED STUDY; EXPRESSION VECTOR; GENE OVEREXPRESSION; GRANULOCYTE; HEMATOPOIETIC STEM CELL; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN FUNCTION; WILD TYPE; ANIMAL; CELL CULTURE; COMPARATIVE STUDY; CYTOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSDUCTION; GENETICS; GRAFT SURVIVAL; GRANULOCYTE PRECURSOR; HEMATOPOIETIC STEM CELL TRANSPLANTATION; METABOLISM; METHODOLOGY; MOUSE MUTANT;

MURINAE;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GENE EXPRESSION REGULATION; GRAFT SURVIVAL; GRANULOCYTE PRECURSOR CELLS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HOMEODOMAIN PROTEINS; MICE; MICE, KNOCKOUT; TRANSCRIPTION FACTORS; TRANSDUCTION, GENETIC;

EID: 33744996081     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2005-0328     Document Type: Article

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