Caspase-3-derived C-terminal product of synphilin-1 displays antiapoptotic function via modulation of the p53-dependent cell death pathway

Journal of Biological Chemistry

Volumn 281, Issue 17, 2006, Pages 11515-11522

  Giaime, Emilie ^a   Sunyach, Claire ^a   Herrant, Magali ^b   Grosso, Sébastien ^b   Auberge, Patrick ^b   McLean, Pamela J ^c   Checler, Frédéric ^a   Alves Da Costa, Cristine ^a  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b INSERM   (France)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISEASES; ENZYME INHIBITION; HUMAN ENGINEERING; HYDROLYSIS; NEUROLOGY; RNA;

ALZHEIMER DISEASE; ANTIAPOPTOTIC FUNCTION; NEUROBLASTOMA CELLS; PARKINSON DISEASE; PROTEOLYSIS;

ENZYMES;

CASPASE 3; CASPASE 6; CYTOPLASM PROTEIN; MESSENGER RNA; OXIDOPAMINE; PROCASPASE 3; PROTEIN P53; PROTEIN SYNPHILIN 1; STAUROSPORINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN HYDROLYSIS; TRANSACTIVATION;

ADRENERGIC AGENTS; APOPTOSIS; CARRIER PROTEINS; CASPASE 3; CASPASES; CELLS, CULTURED; ENZYME INHIBITORS; HUMANS; KIDNEY; NERVE TISSUE PROTEINS; NEUROBLASTOMA; NEURONS; OXIDOPAMINE; POLY(ADP-RIBOSE) POLYMERASES; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STAUROSPORINE; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

MURINAE;

EID: 33744963539     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M508619200     Document Type: Article

References (65)

1. Engelender, S., Kaminsky, Z., Guo, X., Sharp, A. H., Amaravi, R. K., Kleiderlein, J. J., Margolis, R. L., Troncoso, J. C., Lanahan, A. A., Worley, P. F., Dawson, V. L., Dawson, T. M., and Ross, C. A. (1999) Nat. Gen. 22, 110-114
2. Blum, D., Torch, S., Lambeng, N., Nissou, M.-F., Benabid, A.-L., Sadoul, R., and Verna, J.-M. (2001) Prog. Neurobiol. 65, 135-172
3. Morris, H. R. (2005) Ann. Med. 37, 86-96
4. Gasser, T. (2005) Curr. Opin. Neurol. 18, 363-369
5. Pardo, L. M., and van Duijn, C. M. (2005) Mutat. Res. 592, 89-101
6. Bossy-Wetzel, E., Schwarzenbacher, R., and Lipton, S. A. (2004) Nat. Med. 10, Suppl., S2-S9
7. Jellinger, K. (2000) J. Neural Transm. 107, 1-29
8. Maruyama, W., and Naoi, M. (2002) J. Neurol. 249, Suppl. 2, 6-10
9. Lev, N., Melamed, E., and Offen, D. (2003) Prog. Neuro-Psychopharm. Biol. Psych. 27, 245-250
10. Polymeropoulos, M. H., Lavedan, C., Leroy, E., Ide, S. E., Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., Stenroos, E. S., Chandrasekharappa, S., Athanassiadou, A., Papapetropoulos, T., Johnston, W. G., Lazzarini, A. M., Duvoisin, R. C., Di Lorio, G., Golbe, L. I., and Nussbaum, R. L. (1997) Science 276, 2045-2047
11. Spillantini, M. G., Crowther, R. A., Jakes, R., Hasegawa, M., and Goedert, M. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6469-6473
12. Alves da Costa, C., Ancolio, K., and Checler, F. (2000) J. Biol. Chem. 275, 24065-24069
13. Alves da Costa, C., Paitel, E., Vincent, B., and Checler, F. (2002) J. Biol. Chem. 277, 50980-50984
14. Curtius, H. C., Wolhensberger, M., Steinmann, B., and Redweik, S. (1974) J. Chromatogr. 99, 529-540
15. Dawson, T. M. (2000) Cell 101, 115-118
16. Dawson, T. M., and Dawson, V. L. (2002) Nat. Neurosci. 5, 1058-1061
17. Maries, E., Dass, B., Collier, T. J., Kordower, J. H., and Collier, K. S. (2003) Nat. Rev. Neurosci. 4, 727-738
18. Chung, K. K., Zhang, Y., Lim, K. L., Tanaka, Y., Huang, H., Gao, J., Ross, C. A., Dawson, V. L., and Dawson, T. M. (2001) Nat. Med. 7, 1144-1150
19. Wakabayashi, K., Engelender, S., Yoshimoto, M., Tsuji, S., Ross, C. A., and Takahashi, H. (2000) Ann. Neurol. 47, 521-523
20. Wakabayashi, K., Engelender, S., Tanaka, Y., Yoshimoto, M., Mori, F., Tsuji, S., Ross, C. A., and Takahashi, H. (2002) Acta Neuropathol. 103, 209-214
21. Kawamata, H., McLean, P. J., Sharma, N., and Hyman, B. T. (2001) J. Neurochem. 77, 929-934
22. Scott, W. K., Nance, M. A., Watts, R. L., Hubble, J. P., Koller, W. C., Lyons, K., Pahwa, R., Stern, M. B., Colcher, A., Hiner, B. C., Jankovic, J., Ondo, W. G., Allen, F. H., Jr., Goetz, C. G., Small, G. W., Masterman, D., Mastaglia, F., Laing, N. G., Stajich, J. M., Slotterbeck, B., Booze, M. W., Ribble, R. C., Rampersaud, E., West, S. G., Gibson, R. A., Middleton, L. T., Roses, A. D., Haines, J. L., Scott, B. L., Vance, J. M., and Pericak-Vance, M. A. (2001) J. Am. Med. Assoc. 286, 2239-2244
23. Hicks, A. A., Petursson, H., Jonsson, T., Stefansson, H., Johannsdottir, H. S., Sainz, J., Frigge, M. L., Kong, A., Gulcher, J. R., Stefansson, K., and Sveinbjornsdottir, S. (2002) Ann. Neurol. 52, 549-555
24. Pankratz, N., Nichols, W. C., Uniacke, S. K., Halter, C., Rudolph, A., Shults, C., Conneally, P. M., and Foroud, T. (2002) Am. J. Hum. Genet. 71, 124-135
25. Marx, F. P., Holzmann, C., Strauss, K. M., Li, L., Eberhardt, O., Gerhardt, E., Cookson, M. R., Hernandez, D., Farrer, M. J., Kachergus, J., Engelender, S., Ross, C. A., Berger, K., Schols, L., Schulz, J. B., Riess, O., and Kruger, R. (2003) Hum. Mol. Genet. 12, 1223-1231
26. Chun, J., and Jaenisch, R. (1996) Mol. Cell. Neurosci. 7, 304-321
27. Ancolio, K., Dumanchin, C., Barelli, H., Warter, J. M., Brice, A., Campion, D., Frebourg, T., and Checler, F. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 4119-4124
28. Marambaud, P., Alves da Costa, C., Ancolio, K., and Checler, F. (1998) Biochem. Biophys. Res. Commun. 252, 134-138
29. Alves da Costa, C., Paitel, E., Mattson, M. P., Amson, R., Telerman, A., Ancolio, K., and Checler, F. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 4043-4048
30. El-Deiry, W., Kern, S., Pietenpol, J., Kinzler, K., and Vogelstein, B. (1992) Nat. Gen. 1, 45-49
31. Bertolotto, C., Maulon, L., Filippa, N., Baier, G., and Auberger, P. (2000) J. Biol. Chem. 275, 37246-37250
32. Cohen, G. M. (1997) Biochem. J 326, 1-16
33. Vaux, D. L. (1999) Cell Death Differ. 6, 493-494
34. Takahashi, T., Deng, Y., Maruyama, W., Dostert, P., Kawai, M., and Naoi, M. (1994) J. Neural Transm. 98, 107-118
35. Wang, X., Qin, Z.-H., Leng, Y., Wang, Y., Jin, X., Chase, T. N., and Bennett, M. C. (2002) Neurochemistry 83, 1094-1102
36. Kitamura, Y., Kosaka, T., Kakimura, J. I., Matsuoka, Y., Kohno, Y., Nomura, Y., and Taniguchi, T. (1998) Mol. Pharmacol. 54, 1046-1054
37. Pan, T., Li, X., Xie, W., Jankovic, J., and Le, W. (2005) FEBS Lett. 579, 6716-6720
38. Barzilai, A., and Melamed, E. (2003) Trends Mol. Med. 9, 126-132
39. von Bohlen und Halbach, O., Schorer, A., and Krieglstein, K. (2004) Prog. Neurobiol. 73, 151-177
40. Khan, N. L. (2004) Hospital Pharmacist 11, 9-15
41. Anglade, P., Vyas, S., Javoy-Agid, F., Herrero, M. T., Michel, P. P., Marquez, J., Mouatt-Prigent, A., Ruberg, M., Hirsch, E. C., and Agid, Y. (1997) Histol. Histopathol. 12, 25-31
42. Hirsch, E., Hunot, S., Faucheux, B., Agid, Y., Mizuno, Y., Mochizuki, H., Tatton, W., and Olanow, W. (1999) Mov. Disord. 14, 383-385
43. Dawson, T. M., and Dawson, V. L. (2003) Science 302, 819-822
44. Tatton, W. G., Chalmers-redman, R., Brown, D. R., and Tatton, N. (2003) Ann. Neurol. 53, S61-S72
45. Bucciantini, M., Giannoni, E., Chiti, F., Baroni, F., Formigli, L., Zurdo, J., Taddei, N., Ramponi, G., Dobson, C. M., and Stefani, M. (2002) Nature 416, 507-511
46. Bence, N. F., Sampat, R. M., and Kopito, R. R. (2001) Science 292, 1552-1555
47. Buxbaum, J. N. (2003) Trends Biochem. Sci. 28, 585-592
48. Spillantini, M. G., Schmidt, M. L., Lee, V.-Y., Trojanowski, J. Q., Jakes, R., and Goedert, M. (1997) Nature 388, 839-840
49. Krüger, R., Kuhn, W., Müller, T., Woitalla, D., Graeber, M., Kösel, S., Przuntek, H., Epplen, J. T., Schöls, L., and Riess, O. (1998) Nature Genet. 18, 106-108
50. Zarranz, J. J., Alegre, J., Gomez-Esteban, J. C., Lezcano, E., Ros, R., Ampuero, I., Vidal, L., Hoenicka, J., Rodriguez, O., Atares, B., Llorens, V., Tortosa, E. G., Del Ser, T., Munoz, D. G., and De Yebenes, J. G. (2004) Ann. Neurol. 55, 164-173
51. Rajagopalan, S., and Andersen, J. K. (2001) Mech. Ageing Dev. 122, 1499-1510
52. Lee, S.-J. (2003) Antioxidants Redox Signal. 5, 337-348
53. Alves da Costa, C. (2003) Curr. Mol. Med. 3, 17-24
54. Walter, J., Schindzielorz, A., Grünberg, J., and Haass, C. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 1391-1396
55. Alves da Costa, C., Masliah, E., and Checler, F. (2003) J. Biol. Chem. 278, 37330-37335
56. Gervais, F. G., Xu, D., Robertson, G. S., Vaillancourt, J. P., Zhu, Y., Huang, J., LeBlanc, A., Smith, D., Rigby, M., Shearman, M. S., Clarke, E. E., Zheng, H., Van Der Ploeg, L. H. T., Ruffolo, S. C., Thornberry, N. A., Xanthoudakis, S., Zamboni, R. J., Roy, S., and Nicholson, D. W. (1999) Cell 97, 395-406
57. LeBlanc, A., Liu, H., Goodyer, C., Bergeron, C., and Hammond, J. (1999) J. Biol. Chem. 274, 23426-23436
58. Pellegrini, L., Passer, B. J., Tabaton, M., Ganjei, J. K., and D'Adamio, L. (1999) J. Biol. Chem. 274, 21011-21016
59. Weidemann, A., Paliga, K., Dürrwang, U., Reinhard, F. B. M., Schuckert, O., Evin, G., and Masters, C. L. (1999) J. Biol. Chem. 274, 5823-5829
60. Lu, D. C., Rabizadeh, S., Chandra, S., Shayya, R. F., Ellerby, L. M., Ye, X., Salvesen, G. S., Koo, E. H., and Bredesen, D. E. (2000) Nat. Med. 6, 397-404
61. Ciechanover, A. (2001) Nat. Med. 7, 1108-1109
62. Darios, F., Corti, O., Lücking, C. B., Hampe, C., Miuriel, M.-P., Abbas, N., Gu, W.-J., Hirsch, E. C., Rooney, T., Ruberg, M., and Brice, A. (2003) Hum. Mol. Gen. 12, 517-526
63. Jiang, H., Jiang, Q., and Feng, J. (2004) J. Biol. Chem. 279, 54380-54386
64. Kahns, S., Kalai, M., Jacobsen, L. D., Clark, B. F. C., Vandenabeele, P., and Jensen, P. H. (2003) J. Biol. Chem. 278, 23376-23380
65. Tanaka, K., Suzuki, T., Hattori, N., and Mizuno, Y. (2004) Biochim. Biophys. Acta 1695, 235-247