-
1
-
-
0028324454
-
Molecular cloning and structure of a pre-B-cell growth-stimulating factor
-
Nagasawa, T.; Kikutani, H.; Kishimoto, T. Molecular cloning and structure of a pre-B-cell growth-stimulating factor. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 2305-2309.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 2305-2309
-
-
Nagasawa, T.1
Kikutani, H.2
Kishimoto, T.3
-
2
-
-
0029775576
-
The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
-
Bleul, C. C.; Farzan, M.; Choe, H.; Parolin, C.; Clark-Lewis, I.; Sodroski, J.; Springer, T. A. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 1996, 382, 829-833.
-
(1996)
Nature
, vol.382
, pp. 829-833
-
-
Bleul, C.C.1
Farzan, M.2
Choe, H.3
Parolin, C.4
Clark-Lewis, I.5
Sodroski, J.6
Springer, T.A.7
-
3
-
-
16044370087
-
The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1
-
Oberlin, E.; Amara, A.; Bachelerie, F.; Bessia, C.; Virelizier, J.-L.; Arenzana-Seisdedos, F.; Schwartz, O.; Heard, J.-M.; Clark-Lewis, I.; Legler, D. F.; Loetscher, M.; Baggiolini, M.; Moser, B. The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature 1996, 382, 833-835.
-
(1996)
Nature
, vol.382
, pp. 833-835
-
-
Oberlin, E.1
Amara, A.2
Bachelerie, F.3
Bessia, C.4
Virelizier, J.-L.5
Arenzana-Seisdedos, F.6
Schwartz, O.7
Heard, J.-M.8
Clark-Lewis, I.9
Legler, D.F.10
Loetscher, M.11
Baggiolini, M.12
Moser, B.13
-
4
-
-
0027165675
-
Signal sequence trap: A cloning strategy for secreted proteins and type I membrane proteins
-
Tashiro, K.; Tada, H.; Heilker, R.; Shirozu, M.; Nakano, T.; Honjo, T. Signal sequence trap: A cloning strategy for secreted proteins and type I membrane proteins. Science 1993, 261, 600-603.
-
(1993)
Science
, vol.261
, pp. 600-603
-
-
Tashiro, K.1
Tada, H.2
Heilker, R.3
Shirozu, M.4
Nakano, T.5
Honjo, T.6
-
5
-
-
0030002637
-
HIV-1 entry co-factor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
-
Feng, Y.; Broder, C. C.; Kennedy, P. E.; Berger, E. A. HIV-1 entry co-factor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 1996, 272, 872-877.
-
(1996)
Science
, vol.272
, pp. 872-877
-
-
Feng, Y.1
Broder, C.C.2
Kennedy, P.E.3
Berger, E.A.4
-
6
-
-
0033818476
-
Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: A possible role for tumor progression
-
Koshiba, T.; Hosotani, R.; Miyamoto, Y.; Ida, J.; Tsuji, S.; Nakajima, S.; Kawaguchi, M.; Kobayashi, H.; Doi, R.; Hori, T.; Fujii, N.; Imamura, M. Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: A possible role for tumor progression. Clin. Cancer. Res. 2000, 6, 3530-3535.
-
(2000)
Clin. Cancer. Res.
, vol.6
, pp. 3530-3535
-
-
Koshiba, T.1
Hosotani, R.2
Miyamoto, Y.3
Ida, J.4
Tsuji, S.5
Nakajima, S.6
Kawaguchi, M.7
Kobayashi, H.8
Doi, R.9
Hori, T.10
Fujii, N.11
Imamura, M.12
-
7
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
Müller, A.; Homey, B.; Soto, H.; Ge, N.; Catron, D.; Buchanan, M. E.; McClanahan, T.; Murphy, E.; Yuan, W.; Wagner, S. N.; Barrera, J. L.; Mohar, A.; Verastegui, E.; Zlotnik, A. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001, 410, 50-56.
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Müller, A.1
Homey, B.2
Soto, H.3
Ge, N.4
Catron, D.5
Buchanan, M.E.6
McClanahan, T.7
Murphy, E.8
Yuan, W.9
Wagner, S.N.10
Barrera, J.L.11
Mohar, A.12
Verastegui, E.13
Zlotnik, A.14
-
8
-
-
0142102523
-
T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancer
-
Tamamura, H.; Hori, A.; Kanzaki, N.; Hiramatsu, K.; Mizumoto, M.; Nakashima, H.; Yamamoto, N.; Otaka, A.; Fujii, N. T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancer. FEBS Lett. 2003, 550, 79-83.
-
(2003)
FEBS Lett.
, vol.550
, pp. 79-83
-
-
Tamamura, H.1
Hori, A.2
Kanzaki, N.3
Hiramatsu, K.4
Mizumoto, M.5
Nakashima, H.6
Yamamoto, N.7
Otaka, A.8
Fujii, N.9
-
9
-
-
0036464610
-
Distinctive features of "nurselike" cells that differentiate in the context of chronic lymphocytic leukemia
-
Tsukada, N.; Burger, J. A.; Zvaifler, N. J.; Kipps, T. J. Distinctive features of "nurselike" cells that differentiate in the context of chronic lymphocytic leukemia. Blood 2002, 99, 1030-1037.
-
(2002)
Blood
, vol.99
, pp. 1030-1037
-
-
Tsukada, N.1
Burger, J.A.2
Zvaifler, N.J.3
Kipps, T.J.4
-
10
-
-
0038103869
-
Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro
-
Juarez, J.; Bradstock, K. F.; Gottlieb, D. J.; Bendall, L. J. Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro. Leukemia 2003, 17, 1294-1300.
-
(2003)
Leukemia
, vol.17
, pp. 1294-1300
-
-
Juarez, J.1
Bradstock, K.F.2
Gottlieb, D.J.3
Bendall, L.J.4
-
11
-
-
0034544508
-
+ T cell accumulation in rheumatoid arthritis synovium
-
+ T cell accumulation in rheumatoid arthritis synovium. J. Immunol. 2000, 165, 6590-6598.
-
(2000)
J. Immunol.
, vol.165
, pp. 6590-6598
-
-
Nanki, T.1
Hayashida, K.2
El-Gabalawy, H.S.3
Suson, S.4
Shi, K.5
Girschick, H.J.6
Yavuz, S.7
Lipsky, P.E.8
-
12
-
-
3042593906
-
Identification of a CXCR4 antagonist, a T140 analog, as an anti-rheumatoid arthritis agent
-
Tamamura, H.; Fujisawa, M.; Hiramatsu, K.; Mizumoto, M.; Nakashima, H.; Yamamoto, N.; Otaka, A.; Fujii, N. Identification of a CXCR4 antagonist, a T140 analog, as an anti-rheumatoid arthritis agent. FEBS Lett. 2004, 569, 99-104.
-
(2004)
FEBS Lett.
, vol.569
, pp. 99-104
-
-
Tamamura, H.1
Fujisawa, M.2
Hiramatsu, K.3
Mizumoto, M.4
Nakashima, H.5
Yamamoto, N.6
Otaka, A.7
Fujii, N.8
-
13
-
-
0030780377
-
A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection
-
Murakami, T.; Nakajima, T.; Koyanagi, Y.; Tachibana, K.; Fujii, N.; Tamamura, H.; Yoshida, N.; Waki, M.; Matsumoto, A.; Yoshie, O.; Kishimoto, T.; Yamamoto, N.; Nagasawa, T. A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection. J. Exp. Med. 1997, 186, 1389-1393.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1389-1393
-
-
Murakami, T.1
Nakajima, T.2
Koyanagi, Y.3
Tachibana, K.4
Fujii, N.5
Tamamura, H.6
Yoshida, N.7
Waki, M.8
Matsumoto, A.9
Yoshie, O.10
Kishimoto, T.11
Yamamoto, N.12
Nagasawa, T.13
-
14
-
-
0030830661
-
Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4
-
Schols, D.; Struyf, S.; Van Damme, J.; Este, J. A.; Henson, G.; De Clercq, E. Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4. J. Exp. Med. 1997, 186, 1383-1388.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1383-1388
-
-
Schols, D.1
Struyf, S.2
Van Damme, J.3
Este, J.A.4
Henson, G.5
De Clercq, E.6
-
15
-
-
0030773515
-
A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor
-
Doranz, B. J.; Grovit-Ferbas, K.; Sharron, M. P.; Mao, S.-H.; Bidwel Goetz, M.; Daar, E. S.; Doms, R. W.; O'Brien, W. A. A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor. J. Exp. Med. 1997, 186, 1395-1400.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1395-1400
-
-
Doranz, B.J.1
Grovit-Ferbas, K.2
Sharron, M.P.3
Mao, S.-H.4
Bidwel Goetz, M.5
Daar, E.S.6
Doms, R.W.7
O'Brien, W.A.8
-
16
-
-
0031891516
-
AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor
-
Donzella, G. A.; Schols, D.; Lin, S. W.; Este J. A.; Nagashima, K. A.; Maddon, P. J.; Allaway, G. P.; Sakmar, T. P.; Henson, G.; De Clercq, E.; Moore, J. P. AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor. Nat. Med. 1998, 4, 72-77.
-
(1998)
Nat. Med.
, vol.4
, pp. 72-77
-
-
Donzella, G.A.1
Schols, D.2
Lin, S.W.3
Este, J.A.4
Nagashima, K.A.5
Maddon, P.J.6
Allaway, G.P.7
Sakmar, T.P.8
Henson, G.9
De Clercq, E.10
Moore, J.P.11
-
17
-
-
14444282418
-
Inhibition of in vitro and in vivo HIV replication by a distamycin analogue that interferes with chemokine receptor function: A candidate for chemotherapeutic and microbicidal application
-
Howard, O. M. Z.; Oppenheim, J. J.; Hollingshead, M. G.; Covey, J. M.; Bigelow, J.; McCormack, J. J.; Buckheit, R. W., Jr.; Clanton, D. J.; Turpin, J. A.; Rice, W. G. Inhibition of in vitro and in vivo HIV replication by a distamycin analogue that interferes with chemokine receptor function: A candidate for chemotherapeutic and microbicidal application. J. Med. Chem. 1998, 41, 2184-2193.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 2184-2193
-
-
Howard, O.M.Z.1
Oppenheim, J.J.2
Hollingshead, M.G.3
Covey, J.M.4
Bigelow, J.5
McCormack, J.J.6
Buckheit Jr., R.W.7
Clanton, D.J.8
Turpin, J.A.9
Rice, W.G.10
-
18
-
-
0032583575
-
A low molecular weight inhibitor against the chemokine receptor CXCR4: A strong anti-HIV peptide T140
-
Tamamura, H.; Xu, Y.; Hattori, T.; Zhang, X.; Arakaki, R.; Kanbara, K.; Omagari, A.; Otaka, A.; Ibuka, T.; Yamamoto, N.; Nakashima, H.; Fujii, N. A low molecular weight inhibitor against the chemokine receptor CXCR4: A strong anti-HIV peptide T140. Biochem. Biophys. Res. Commun. 1998, 253, 877-882.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.253
, pp. 877-882
-
-
Tamamura, H.1
Xu, Y.2
Hattori, T.3
Zhang, X.4
Arakaki, R.5
Kanbara, K.6
Omagari, A.7
Otaka, A.8
Ibuka, T.9
Yamamoto, N.10
Nakashima, H.11
Fujii, N.12
-
19
-
-
0034606466
-
Pharmacophore identification of a specific CXCR4 inhibitor, T140, leads to development of effective anti-HIV agents with very high selectivity indexes
-
Tamamura, H.; Omagari, A.; Oishi, S.; Kanamoto, T.; Yamamoto, N.; Peiper, S. C.; Nakashima, H.; Otaka, A.; Fujii, N. Pharmacophore identification of a specific CXCR4 inhibitor, T140, leads to development of effective anti-HIV agents with very high selectivity indexes. Bioorg. Med. Chem. Lett. 2000, 10, 2633-2637,
-
(2000)
Bioorg. Med. Chem. Lett.
, vol.10
, pp. 2633-2637
-
-
Tamamura, H.1
Omagari, A.2
Oishi, S.3
Kanamoto, T.4
Yamamoto, N.5
Peiper, S.C.6
Nakashima, H.7
Otaka, A.8
Fujii, N.9
-
20
-
-
10744227507
-
Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries
-
Fujii, N.; Oishi, S.; Hiramatsu, K.; Araki, T.; Ueda, S.; Tamamura, H.; Otaka, A.; Kusano, S.; Terakubo, S.; Nakashima, H.; Broach, J. A.; Trent, J. O.; Wang, Z.; Peiper, S. C. Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries. Angew. Chem., Int. Ed. 2003, 42, 3251-3253.
-
(2003)
Angew. Chem., Int. Ed.
, vol.42
, pp. 3251-3253
-
-
Fujii, N.1
Oishi, S.2
Hiramatsu, K.3
Araki, T.4
Ueda, S.5
Tamamura, H.6
Otaka, A.7
Kusano, S.8
Terakubo, S.9
Nakashima, H.10
Broach, J.A.11
Trent, J.O.12
Wang, Z.13
Peiper, S.C.14
-
21
-
-
2942720410
-
Two orthogonal approaches to overcome multi-drug resistant HIV-1s: Development of protease inhibitors and entry inhibitors based on CXCR4 antagonists
-
Tamamura, H.; Fujii, N. Two Orthogonal Approaches to Overcome Multi-Drug Resistant HIV-1s: Development of Protease Inhibitors and Entry Inhibitors Based on CXCR4 Antagonists. Curr. Drug Targets-Infectious Disorders 2004, 4, 103-110.
-
(2004)
Curr. Drug Targets-Infectious Disorders
, vol.4
, pp. 103-110
-
-
Tamamura, H.1
Fujii, N.2
-
22
-
-
0037388121
-
A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity
-
Ichiyama, K.; Yokoyama-Kumakura, S.; Tanaka, Y.; Tanaka, R.; Hirose, K.; Bannai, K.; Edamatsu, T.; Yanaka, M.; Niitani, Y.; Miyano-Kurosaki, N.; Takaku, H.; Koyanagi, Y.; Yamamoto, N. A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 4185-4190.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 4185-4190
-
-
Ichiyama, K.1
Yokoyama-Kumakura, S.2
Tanaka, Y.3
Tanaka, R.4
Hirose, K.5
Bannai, K.6
Edamatsu, T.7
Yanaka, M.8
Niitani, Y.9
Miyano-Kurosaki, N.10
Takaku, H.11
Koyanagi, Y.12
Yamamoto, N.13
-
23
-
-
19944431731
-
Stereoselective synthesis of [L-Arg,L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogs of the CXCR4 antagonist FC131
-
Tamamura, H.; Hiramatsu, K.; Ueda, S.; Wang, Z.; Kusano, S.; Terakubo, S.; Trent, J. O.; Peiper, S. C.; Yamamoto, N.; Nakashima, H.; Otaka, A.; Fujii, N. Stereoselective synthesis of [L-Arg,L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogs of the CXCR4 antagonist FC131. J. Med. Chem. 2005, 48, 380-391.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 380-391
-
-
Tamamura, H.1
Hiramatsu, K.2
Ueda, S.3
Wang, Z.4
Kusano, S.5
Terakubo, S.6
Trent, J.O.7
Peiper, S.C.8
Yamamoto, N.9
Nakashima, H.10
Otaka, A.11
Fujii, N.12
-
24
-
-
20944452022
-
Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide-scaffolds
-
Tamamura, H.; Araki, T.; Ueda, S.; Wang, Z.; Oishi, S.; Esaka, A.; Trent, J. O.; Nakashima, H.; Yamamoto, N.; Peiper, S. C.; Otaka, A.; Fujii, N. Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide-scaffolds. J. Med. Chem. 2005, 48, 3280-3289.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 3280-3289
-
-
Tamamura, H.1
Araki, T.2
Ueda, S.3
Wang, Z.4
Oishi, S.5
Esaka, A.6
Trent, J.O.7
Nakashima, H.8
Yamamoto, N.9
Peiper, S.C.10
Otaka, A.11
Fujii, N.12
-
25
-
-
0037024162
-
First artificial receptors and chemosensors toward phosphorylated peptide in aqueous solution
-
Ojida, A.; Mito-oka, Y.; Inoue, M.; Hamachi, I. First artificial receptors and chemosensors toward phosphorylated peptide in aqueous solution. J. Am. Chem. Soc. 2002, 124, 6256-6258.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 6256-6258
-
-
Ojida, A.1
Mito-oka, Y.2
Inoue, M.3
Hamachi, I.4
-
26
-
-
0035479682
-
Zn(II) dipicolylamine-based artificial receptor as a new entry for surface recognition of α-helical peptides in aqueous solution
-
Mito-oka, Y.; Tsukiji, S.; Hiraoka, T.; Kasagi, N.; Shinkai, S.; Hamachi, I. Zn(II) dipicolylamine-based artificial receptor as a new entry for surface recognition of α-helical peptides in aqueous solution. Tetrahedron Lett. 2001, 42, 7059-7062.
-
(2001)
Tetrahedron Lett.
, vol.42
, pp. 7059-7062
-
-
Mito-oka, Y.1
Tsukiji, S.2
Hiraoka, T.3
Kasagi, N.4
Shinkai, S.5
Hamachi, I.6
-
27
-
-
0041429638
-
Cross-linking strategy for molecular recognition and fluorescent sensing of a multiphosphorylated peptide in aqueous solution
-
Ojida, A.; Inoue, M.; Mito-oka, Y.; Hamachi, I. Cross-linking strategy for molecular recognition and fluorescent sensing of a multiphosphorylated peptide in aqueous solution. J. Am. Chem. Soc. 2003, 125, 10184-10185.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 10184-10185
-
-
Ojida, A.1
Inoue, M.2
Mito-oka, Y.3
Hamachi, I.4
-
28
-
-
1542366681
-
Molecular recognition and fluorescence sensing of monophosphorylated peptides in aqueous solution by bis(zinc(II)-dipicolylamine)-based artificial receptors
-
Ojida, A.; Mito-oka, Y.; Sada, K.; Hamachi, I. Molecular recognition and fluorescence sensing of monophosphorylated peptides in aqueous solution by bis(zinc(II)-dipicolylamine)-based artificial receptors. J. Am. Chem. Soc. 2004, 126, 2454-2463.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 2454-2463
-
-
Ojida, A.1
Mito-oka, Y.2
Sada, K.3
Hamachi, I.4
-
29
-
-
0025142350
-
Reductive animation of aldehydes and ketones by using sodium triacetoxyborohydride
-
Abdel-Magid, A. F.; Maryanoff, C. A.; Carson, K. G. Reductive animation of aldehydes and ketones by using sodium triacetoxyborohydride. Tetrahedron Lett. 1990, 31, 5595-5598.
-
(1990)
Tetrahedron Lett.
, vol.31
, pp. 5595-5598
-
-
Abdel-Magid, A.F.1
Maryanoff, C.A.2
Carson, K.G.3
-
30
-
-
0142096799
-
Synthesis of potent CXCR4 inhibitors possessing low cytotoxicity and improved biostability based on T140 derivatives
-
Tamamura, H.; Hiramatsu, K.; Kusano, S.; Terakubo, S.; Yamamoto, N.; Trent, J. O.; Wang, Z.; Peiper, S. C.; Nakashima, H.; Otaka, A.; Fujii, N. Synthesis of potent CXCR4 inhibitors possessing low cytotoxicity and improved biostability based on T140 derivatives. Org. Biomol. Chem. 2003, 1, 3656-3662.
-
(2003)
Org. Biomol. Chem.
, vol.1
, pp. 3656-3662
-
-
Tamamura, H.1
Hiramatsu, K.2
Kusano, S.3
Terakubo, S.4
Yamamoto, N.5
Trent, J.O.6
Wang, Z.7
Peiper, S.C.8
Nakashima, H.9
Otaka, A.10
Fujii, N.11
-
31
-
-
0027394031
-
The biochemical basis of zinc physiology
-
Vallee, B. L.; Falchuk, K. H. The biochemical basis of zinc physiology. Phys. Rev. 1993, 73, 79-118.
-
(1993)
Phys. Rev.
, vol.73
, pp. 79-118
-
-
Vallee, B.L.1
Falchuk, K.H.2
|