Transferrin receptor 1 is differentially required in lymphocyte development

Blood

Volumn 102, Issue 10, 2003, Pages 3711-3718

  Ned, Renée M ^b   Swat, Wojciech ^b   Andrews, Nancy C ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD71 ANTIGEN; CD8 ANTIGEN; IMMUNOGLOBULIN M; RAG2 PROTEIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ARTICLE; CELL MATURATION; CHIMERA; CONTROLLED STUDY; EMBRYO DEVELOPMENT; ENDOCYTOSIS; ERYTHROPOIESIS; HEMATOPOIETIC SYSTEM; HOMOZYGOSITY; IRON TRANSPORT; LIGAND BINDING; LYMPHOCYTE; LYMPHOPOIESIS; MAMMAL CELL; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; THYMOCYTE; WILD TYPE;

EID: 0242579159     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-04-1086     Document Type: Article

References (56)

1. Andrews NC. Iron homeostasis: insights from genetics and animal models. Nat Rev Genet. 2000; 1:208-217.
2. Levy JE, Jin O, Fujiwara Y, Kuo F, Andrews NC. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Nat Genet. 1999;21:396-399.
3. Trenor CC, Campagna DR, Sellers VM, Andrews NC, Fleming MD. The molecular defect in hypotransferrinemic mice. Blood. 2000;96:1113-1118.
4. Bernstein SE. Hereditary hypotransferrinemia with hemosiderosis, a murine disorder resembling human atransferrinemia. J Lab Clin Med. 1987; 110:690-705.
5. Hamill RL, Woods JC, Cook BA. Congenital atransferrinemia: a case report and review of the literature. Am J Clin Pathol. 1991;96:215-218.
6. Dickinson T, Connor JR. Histological analysis of selected brain regions of hypotransferrinemic mice. Brain Res. 1994;635:169-178.
7. Mortensen RM, Conner DA, Chao S, Gesterfer-Lowrance AAT, Seidman JG. Production of homozygous mutant ES cells with a single targeting construct. Mol Cell Biol. 1992;12:2391-2395.
8. Whitney JB, 3rd. Simplified typing of mouse hemoglobin (Hbb) phenotypes using cystamine. Biochem Genet. 1978;16:667-672.
9. Shinkai Y, Rathbun G, Lam KP, et al. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell. 1992; 68:855-867.
10. Chen J, Lansford R, Stewart V, Young F, Alt FW. RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development. Proc Natl Acad Sci U S A. 1993;90:4528-4532.
11. Ledbetter JA, Goding JW, Tsu TT, Herzenberg LA. A new mouse lymphoid alloantigen (Lgp100) recognized by a monoclonal rat antibody. Immunogenetics. 1979;8:347-360.
12. Hogarth PM, Craig J, McKenzie IF. A monoclonal antibody detecting the Ly-9.2 (Lgp 100) cell-membrane alloantigen. Immunogenetics. 1980;11: 65-74.
13. Porcher C, Swat W, Rockwell K, Fujiwara K, Alt FW, Orkin SH. The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages. Cell. 1996;86:47-57.
14. Chan RY, Ponka P, Schulman HM. Transferrin-receptor-independent but iron-dependent proliferation of variant Chinese hamster ovary cells. Exp Cell Res. 1992;202:326-336.
15. Thorstensen K, Trinder D, Zak O, Aisen P. Uptake of iron from N-terminal half-transferrin by isolated rat hepatocytes. Evidence of transferrin-receptor-independent iron uptake. Eur J Biochem. 1995; 232:129-133.
16. Konijn AM, Meyron-Holtz EG, Fibach E, Gelvan D. Cellular ferritin uptake: a highly regulated pathway for iron assimilation in human erythroid precursor cells. Adv Exp Med Biol. 1994;356:189-197.
17. Gelvan D, Fibach E, Meyron-Holtz EG, Konijn AM. Ferritin uptake by human erythroid precursors is a regulated iron uptake pathway. Blood. 1996;88:3200-3207.
18. Meyron-Holtz EG, Vaisman B, Cabantchik ZI, et al. Regulation of intracellular iron metabolism in human erythroid precursors by internalized extra-cellular ferritin. Blood. 1999;94:3205-3211.
19. Goto Y, Paterson M, Listowsky I. Iron uptake and regulation of ferritin synthesis by hepatoma cells in hormone-supplemented serum-free media. J Biol Chem. 1983;258:5248-5255.
20. Baker E, Baker SM, Morgan EH. Characterisation of non-transferrin-bound iron (ferric citrate) uptake by rat hepatocytes in culture. Biochim Biophys Acta. 1998;1380:21-30.
21. Kaplan J, Jordan I, Sturrock A. Regulation of the transferrin-independent iron transport system in cultured cells. J Biol Chem. 1991;266:2997-3004.
22. Sturrock A, Alexander J, Lamb J, Craven CM, Kaplan J. Characterization of a transferrin-independent uptake system for iron in HeLa cells. J Biol Chem. 1990;265:3139-3145.
23. Hodgson LL, Quail EA, Morgan EH. Iron transport mechanisms in reticulocytes and mature erythrocytes. J Cell Physiol. 1995;162:181-190.
24. Craven CM, Alexander J, Eldridge M, Kushner JP, Bernstein S, Kaplan J. Tissue distribution and clearance kinetics of non-transferrin-bound iron in the hypotransferrinemic mouse: a rodent model for hemochromatosis. Proc Natl Acad Sci U S A. 1987;84:3457-3461.
25. Beutler E, Gelbart T, Lee P, Trevino R, Fernandez MA, Fairbanks VF. Molecular characterization of a case of atransferrinemia. Blood. 2000;96:4071-4074.
26. Yang J, Goetz D, Li JY, et al. An iron delivery pathway mediated by a lipocalin. Mol Cell. 2002; 10:1045-1056.
27. Brock JH. The effect of iron and transferrin on the response of serum-free cultures of mouse lymphocytes to concanavalin A and lipopolysaccharide. Immunology. 1981;43:387-392.
28. Dillner-Centerlind ML, Hammarstrom S, Perlmann P. Transferrin can replace serum for in vitro growth of mitogen-stimulated T lymphocytes. Eur J Immunol. 1979;9:942-948.
29. Futran J, Kemp JD, Field EH, Vora A, Ashman RF. Transferrin receptor synthesis is an early event in B cell activation. J Immunol. 1989;143: 787-792.
30. Kronke M, Leonard WJ, Depper JM, Greene WC. Sequential expression of genes involved in human T lymphocyte growth and differentiation. J Exp Med. 1985;161:1593-1598.
31. Pelosi E, Testa U, Louache F, et al. Expression of transferrin receptors in phytohemagglutinin-stimulated human T-lymphocytes. Evidence for a three-step model. J Biol Chem. 1986;261:3036-3042.
32. Neckers LM, Yenokida G, James SP. The role of the transferrin receptor in human B lymphocyte activation. J Immunol. 1984;133:2437-2441.
33. Hammarstrom ML, Axelsson B, Ivansen M, Hammarstrom S, Perlmann P. Transferrin receptors on mitogen-stimulated human thymus-derived lymphocytes. Scand J Immunol. 1982;16:355-360.
34. Neckers LM, Cossman J. Transferrin receptor induction in mitogen-stimulated human T lymphocytes is required for DNA synthesis and cell division and is regulated by interleukin 2. Proc Natl Acad Sci U S A. 1983;80:3494-3498.
35. Pattanapanyasat K. Expression of cell-surface transferrin receptor following in vitro stimulation of peripheral blood lymphocytes in patients with beta-thalassaemia and iron-deficiency anaemia. Eur J Haematol. 1990;44:190-195.
36. Pattanapanyasat K, Hoy TG. Expression of cell surface transferrin receptor and intracellular ferritin after in vitro stimulation of peripheral blood T lymphocytes. Eur J Haematol. 1991;47:140-145.
37. Neckers LM, Yenokida G, Trepel JB, Lipford E, James S. Transferrin receptor induction is required for human B-lymphocyte activation but not for immunoglobulin secretion. J Cell Biochem. 1985;27:377-389.
38. Kemp JD, Thorson JA, Gomez F, Smith KM, Cowdery JS, Ballas ZK. Inhibition of lymphocyte activation with anti-transferrin receptor Mabs: a comparison of three reagents and further studies of their range of effects and mechanism of action. Cell Immunol. 1989;122:218-230.
39. Pelosi-Testa E, Samoggia P, Giannella G, et al. Mechanisms underlying T-lymphocyte activation: mitogen initiates and IL-2 amplifies the expression of transferrin receptors via intracellular iron level. Immunology. 1988;64:273-279.
40. Seiser C, Teixeira S, Kuhn LC. Interleukin-2-dependent transcriptional and post-transcriptional regulation of transferrin receptor mRNA. J Biol Chem. 1993;268:13074-13080.
41. Golding S, Young SP. Iron requirements of human lymphocytes: relative contributions of intra- and extra-cellular iron. Scand J Immunol. 1995;41: 229-236.
42. Zuniga-Pflucker JC, Lenardo MJ. Regulation of thymocyte development from immature progenitors. Curr Opin Immunol. 1996;8:215-224.
43. Brekelmans P, van Soest P, Voerman J, Platenburg PP, Leenen PJ, van Ewijk W. Transferrin receptor expression as a marker of immature cycling thymocytes in the mouse. Cell Immunol. 1994;159:331-339.
44. Brekelmans P, van Soest P, Leenen PJ, van Ewijk W. Inhibition of proliferation and differentiation during early T cell development by anti-transferrin receptor antibody. Eur J Immunol. 1994;24:2896-2902.
45. Rolink A, Melchers F. B-cell development in the mouse. Immunol Lett. 1996;54:157-161.
46. Osmond DG, Rolink A, Melchers F. Murine B lymphopoiesis: towards a unified model. Immunol Today. 1998;19:65-68.
47. Rolink A, ten Boekel E, Melchers F, Fearon DT, Krop I, Andersson J. A subpopulation of B220 cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors. J Exp Med. 1996;183:187-194.
48. Osmond DG. B cell development in the bone marrow. Semin Immunol. 1990;2:173-180.
49. Osmond DG. Proliferation kinetics and the lifespan of B cells in central and peripheral lymphoid organs. Curr Opin Immunol. 1991;3:179-185.
50. Park YH, Osmond DG. Dynamics of early B lymphocyte precursor cells in mouse bone marrow: proliferation of cells containing terminal deoxynucleotidyl transferase. Eur J Immunol. 1989;19: 2139-2144.
51. Djeha A, Brock JH. Uptake and intracellular handling of iron from transferrin and iron chelates by mitogen stimulated mouse lymphocytes. Biochim Biophys Acta. 1992;1133:147-152.
52. Salmeron A, Borroto A, Fresno M, Crumpton MJ, Ley SC, Alarcon B. Transferrin receptor induces tyrosine phosphorylation in T cells and is physically associated with the TCR zeta-chain. J Immunol. 1995;154:1675-1683.
53. Kitamura D, Kudo A, Schaal S, Muller W, Melchers F, Rajewsky K. A critical role of lambda 5 protein in B cell development. Cell. 1992;69:823-831.
54. Kirchner J, Forbush KA, Bevan MJ. Identification and characterization of thymus LIM protein: targeted disruption reduces thymus cellularity. Mol Cell Biol. 2001;21:8592-8604.
55. Revest JM, Suniara RK, Kerr K, Owen JJ, Dickson C. Development of the thymus requires signaling through the fibroblast growth factor receptor R2-IIIb. J Immunol. 2001;167:1954-1961.
56. Peschon JJ, Morrissey PJ, Grabstein, KH, et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med. 1994;180:1955-1960.