A novel scintillation proximity assay for fatty acid amide hydrolase compatible with inhibitor screening

Analytical Biochemistry

Volumn 354, Issue 1, 2006, Pages 35-42

  Wang, Yuren ^a   Xu, Jun ^a   Uveges, Albert ^a   Ramarao, Manjunath K ^a   Rogers, Kathryn E ^a   Jones, Philip G ^a  

^a PFIZER INC   (United States)

Author keywords

Enzyme binding assay; Enzyme inhibitors; Fatty acid amide hydrolase; Methanandamide; Scintillation proximity assay

Indexed keywords

AMIDES; HYDROLASES; SCINTILLATION;

DOSE-DEPENDENT MANNER; ENZYME BINDING; ENZYME INHIBITORS; FATTY ACID AMIDE HYDROLASE; HIGH THROUGHPUT SCREENING; INHIBITOR SCREENINGS; METHANANDAMIDE; SPECIFIC INTERACTION;

FATTY ACIDS;

FATTY ACID AMIDASE; HYDROLASE INHIBITOR; METHANANDAMIDE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CELL LINE; COMPETITIVE INHIBITION; DOSE RESPONSE; ENZYME BINDING; EVALUATION; HIGH THROUGHPUT SCREENING; HYDROLYSIS; IC 50; INCUBATION TIME; ISOTOPE LABELING; METHODOLOGY; MICROSOME; NONHUMAN; PRIORITY JOURNAL; SCINTILLATION; TECHNOLOGY; VECTORCARDIOGRAPHY;

EID: 33744518269     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2006.04.005     Document Type: Article

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