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Volumn 20, Issue 6, 2006, Pages 958-964

Genomic gain at 6p21: A new cryptic molecular rearrangement in secondary myelodysplastic syndrome and acute myeloid leukemia

Author keywords

6p rearrangements; Genomic gain; Primary and secondary myeloid malignancies

Indexed keywords

DNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETV 7; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

EID: 33744494284     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404208     Document Type: Article
Times cited : (12)

References (40)
  • 1
    • 0026780698 scopus 로고
    • The translocation (6;9)(p23;q34) shows consistent rearrangement of two genes and defines a myeloproliferative disorder with specific clinical features
    • Soekarman D, von Lindern M, Daenen S, de Jong B, Fonatch C, Heinze B et al. The translocation (6;9)(p23;q34) shows consistent rearrangement of two genes and defines a myeloproliferative disorder with specific clinical features. Blood 1992; 79: 2990-2997.
    • (1992) Blood , vol.79 , pp. 2990-2997
    • Soekarman, D.1    von Lindern, M.2    Daenen, S.3    de Jong, B.4    Fonatch, C.5    Heinze, B.6
  • 2
    • 4344608433 scopus 로고    scopus 로고
    • Acute myeloid leukemia with t(6;9)(p23;q34) is associated with dysplasia and a high frequency of FLT3 mutations
    • Oyarzo MP, Lin P, Glassman A, Bueso-Ramos CE, Luthra R, Medeiros J. Acute myeloid leukemia with t(6;9)(p23;q34) is associated with dysplasia and a high frequency of FLT3 mutations. Hematopathology 2004; 122: 348-358.
    • (2004) Hematopathology , vol.122 , pp. 348-358
    • Oyarzo, M.P.1    Lin, P.2    Glassman, A.3    Bueso-Ramos, C.E.4    Luthra, R.5    Medeiros, J.6
  • 3
    • 0031028263 scopus 로고    scopus 로고
    • A recurring translocation, t(3;6)(q27;p21), in non-Hodgkin's lymphoma results in replacement of the 5′ regulatory region of BCL-6 with a novel H4 histone gene
    • Akasaka T, Miura I, Takahashi N, Akasaka H, Yonetani N, Ohno H et al. A recurring translocation, t(3;6)(q27;p21), in non-Hodgkin's lymphoma results in replacement of the 5′ regulatory region of BCL-6 with a novel H4 histone gene. Cancer Res 1997; 57: 7-12.
    • (1997) Cancer Res , vol.57 , pp. 7-12
    • Akasaka, T.1    Miura, I.2    Takahashi, N.3    Akasaka, H.4    Yonetani, N.5    Ohno, H.6
  • 4
    • 0034797156 scopus 로고    scopus 로고
    • Splicing factor SRP20 is a novel partner of BCL6 in a t(3;6)(q27;p21) translocation in transformed follicular lymphoma
    • Chen W, Itoyama T, Chaganti RSK. Splicing factor SRP20 is a novel partner of BCL6 in a t(3;6)(q27;p21) translocation in transformed follicular lymphoma. Genes Chromosome Cancer 2001; 32: 281-284.
    • (2001) Genes Chromosome Cancer , vol.32 , pp. 281-284
    • Chen, W.1    Itoyama, T.2    Chaganti, R.S.K.3
  • 5
    • 0035525788 scopus 로고    scopus 로고
    • Cyclin D3 is a target of t(6;14)(p21.1;q32.3) of mature B-cell malignancies
    • Sonoki T, Harder L, Horsman DE, Karran L, Taniguchi I, Willis TG et al. Cyclin D3 is a target of t(6;14)(p21.1;q32.3) of mature B-cell malignancies. Blood 2001; 98: 2837-2844.
    • (2001) Blood , vol.98 , pp. 2837-2844
    • Sonoki, T.1    Harder, L.2    Horsman, D.E.3    Karran, L.4    Taniguchi, I.5    Willis, T.G.6
  • 6
    • 0035412392 scopus 로고    scopus 로고
    • Cyclin D3 at 6p21 is dysregulated by recurrent chromosomal translocations to immunoglobulin loci in multiple myeloma
    • Shaughnessy J, Gabrera A, Qi Y, Brents L, Zhan F, Tian E et al. Cyclin D3 at 6p21 is dysregulated by recurrent chromosomal translocations to immunoglobulin loci in multiple myeloma. Blood 2001; 98: 217-223.
    • (2001) Blood , vol.98 , pp. 217-223
    • Shaughnessy, J.1    Gabrera, A.2    Qi, Y.3    Brents, L.4    Zhan, F.5    Tian, E.6
  • 7
    • 84984756503 scopus 로고    scopus 로고
    • Deregulation of MUM/IRF4 by chromosomal translocation in multiple myeloma
    • Iida S, Rao PH, Butler M, Corradini P, Boccadoro M, Klein B et al. Deregulation of MUM/IRF4 by chromosomal translocation in multiple myeloma. Nat Genet 1997; 17: 226-230.
    • (1997) Nat Genet , vol.17 , pp. 226-230
    • Iida, S.1    Rao, P.H.2    Butler, M.3    Corradini, P.4    Boccadoro, M.5    Klein, B.6
  • 8
    • 0025818349 scopus 로고
    • Cytogeentics of secondary myelodysplasia (sMDS) and acute nonlymphocytic leukemia (sANLL)
    • Johansson B, Mertens F, Heim S, Kristoffersson U, Mitelman F. Cytogeentics of secondary myelodysplasia (sMDS) and acute nonlymphocytic leukemia (sANLL). Eur J Haematol 1991; 47: 17-27.
    • (1991) Eur J Haematol , vol.47 , pp. 17-27
    • Johansson, B.1    Mertens, F.2    Heim, S.3    Kristoffersson, U.4    Mitelman, F.5
  • 10
    • 0024455497 scopus 로고
    • Chromosome 6p rearrangements appear to be secondary changes in various haematological malignancies
    • Huret JL, Schoenwald M, Brizard A, Guilhot F, Vilmer E, Tanzer J. Chromosome 6p rearrangements appear to be secondary changes in various haematological malignancies. Leukemia Res 1989; 13: 819-824.
    • (1989) Leukemia Res , vol.13 , pp. 819-824
    • Huret, J.L.1    Schoenwald, M.2    Brizard, A.3    Guilhot, F.4    Vilmer, E.5    Tanzer, J.6
  • 13
    • 0029867401 scopus 로고    scopus 로고
    • Derivative (6)t(1;6)(q22;p21) revealed in bone marrow cells by FISH 9 months before diagnosis of acute T-lymphoblastic leukemia
    • Michalovà K, Lemez P, Bartsch O, Brezinova J, Zemanova Z, Jelinek J et al. Derivative (6)t(1;6)(q22;p21) revealed in bone marrow cells by FISH 9 months before diagnosis of acute T-lymphoblastic leukemia. Cancer Genet Cytogenet 1996; 86: 131-135.
    • (1996) Cancer Genet Cytogenet , vol.86 , pp. 131-135
    • Michalovà, K.1    Lemez, P.2    Bartsch, O.3    Brezinova, J.4    Zemanova, Z.5    Jelinek, J.6
  • 14
    • 0034005973 scopus 로고    scopus 로고
    • Trisomy of the long arm of chromosome 1 resulting in a dicentric derivative (6)t(1;6) chromosome in a child with myelodysplastic syndrome following treatment for a primitive neuroectodermal tumor
    • Mathew S, Head D, Rodriguez-Galindo C, Raimondi S. Trisomy of the long arm of chromosome 1 resulting in a dicentric derivative (6)t(1;6) chromosome in a child with myelodysplastic syndrome following treatment for a primitive neuroectodermal tumor. Leukemia Lymphoma 2000; 37: 213-218.
    • (2000) Leukemia Lymphoma , vol.37 , pp. 213-218
    • Mathew, S.1    Head, D.2    Rodriguez-Galindo, C.3    Raimondi, S.4
  • 17
    • 20344407088 scopus 로고    scopus 로고
    • The hypereosinophilic syndrome: Fluorescence in situ hybridization detects the del(4)(q12)-FIP1L1/PDGFRA but not genomic rearrangements of other tyrosine kinases
    • La Starza R, Specchia G, Cuneo A, Beacci D, Nozzoli C, Luciano L et al. The hypereosinophilic syndrome: Fluorescence in situ hybridization detects the del(4)(q12)-FIP1L1/PDGFRA but not genomic rearrangements of other tyrosine kinases. Haematologica 2005; 90: 596-601.
    • (2005) Haematologica , vol.90 , pp. 596-601
    • La Starza, R.1    Specchia, G.2    Cuneo, A.3    Beacci, D.4    Nozzoli, C.5    Luciano, L.6
  • 18
    • 18444390564 scopus 로고    scopus 로고
    • Interpretation of the complex karyotype and identification of a new 6p amplicon by integrated comparative genomic hybridization and fluorescence in situ hybridization investigations on the U937-I cell line
    • Matteucci C, La Starza R, Crescenzi B, Falzetti D, Romoli S, Emiliani C et al. Interpretation of the complex karyotype and identification of a new 6p amplicon by integrated comparative genomic hybridization and fluorescence in situ hybridization investigations on the U937-I cell line. Cancer Genet Cytogenet 2002; 135: 28-34.
    • (2002) Cancer Genet Cytogenet , vol.135 , pp. 28-34
    • Matteucci, C.1    La Starza, R.2    Crescenzi, B.3    Falzetti, D.4    Romoli, S.5    Emiliani, C.6
  • 19
    • 0036934475 scopus 로고    scopus 로고
    • Pooled analysis of clinical and cytogenetic features in treatment-related and de novo adult acute myeloid leukemia and myelodysplastic syndromes based on a consecutive series of 761 patients analyzed 1976-1993 and on 5098 unselected cases reported in the literature 1974-2001
    • Mauritzson N, Albin M, Rylander L, Billstrom R, Ahlgren T, Mikoczy Z et al. Pooled analysis of clinical and cytogenetic features in treatment-related and de novo adult acute myeloid leukemia and myelodysplastic syndromes based on a consecutive series of 761 patients analyzed 1976-1993 and on 5098 unselected cases reported in the literature 1974-2001. Leukemia 2002; 16: 2366-2378.
    • (2002) Leukemia , vol.16 , pp. 2366-2378
    • Mauritzson, N.1    Albin, M.2    Rylander, L.3    Billstrom, R.4    Ahlgren, T.5    Mikoczy, Z.6
  • 20
    • 0015891353 scopus 로고
    • A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents
    • Sasaki MS, Tonomura A. A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents. Cancer Res 1973; 33: 1829-1836.
    • (1973) Cancer Res , vol.33 , pp. 1829-1836
    • Sasaki, M.S.1    Tonomura, A.2
  • 21
    • 0033763360 scopus 로고    scopus 로고
    • MLL amplification in acute leukaemia: A United Kingdom Cancer Cytogenetics Group (UKCCG) study
    • Cuthbert G, Thompson K, McCullough S, Watmore A, Dickinson H, Telford N et al. MLL amplification in acute leukaemia: A United Kingdom Cancer Cytogenetics Group (UKCCG) study. Leukemia 2000; 14: 1885-1891.
    • (2000) Leukemia , vol.14 , pp. 1885-1891
    • Cuthbert, G.1    Thompson, K.2    McCullough, S.3    Watmore, A.4    Dickinson, H.5    Telford, N.6
  • 22
    • 0033934638 scopus 로고    scopus 로고
    • Double minute chromosomes and c-MYC amplification in a child with secondary myelodysplastic syndrome after treatment for acute lymphoblastic leukemia
    • Mathew S, Lorsbach RB, Shearer P, Sandlund JT, Raimondi SC. Double minute chromosomes and c-MYC amplification in a child with secondary myelodysplastic syndrome after treatment for acute lymphoblastic leukemia. Leukemia 2000; 14: 1314-1315.
    • (2000) Leukemia , vol.14 , pp. 1314-1315
    • Mathew, S.1    Lorsbach, R.B.2    Shearer, P.3    Sandlund, J.T.4    Raimondi, S.C.5
  • 24
    • 0036468807 scopus 로고    scopus 로고
    • Genome architecture, rearrangements and genomic disorders
    • Stankiewicz P, Lupski JR. Genome architecture, rearrangements and genomic disorders. Trends Genet 2002; 18: 74-82.
    • (2002) Trends Genet , vol.18 , pp. 74-82
    • Stankiewicz, P.1    Lupski, J.R.2
  • 25
    • 0034028921 scopus 로고    scopus 로고
    • Structure of chromosomal duplicons and their role in mediating human genomic disorders
    • Ji Y, Eicher EE, Schwartz S, Nicholls RD. Structure of chromosomal duplicons and their role in mediating human genomic disorders. Genome Res 2000; 10: 597-610.
    • (2000) Genome Res , vol.10 , pp. 597-610
    • Ji, Y.1    Eicher, E.E.2    Schwartz, S.3    Nicholls, R.D.4
  • 26
    • 0037162516 scopus 로고    scopus 로고
    • A 76 Kb duplicon maps close to the BCR gene on chromosome 22 and the ABL gene on chromosome 9: Possible involvement in the genesis of the philadelphia chromosome translocation
    • Saglio G, Storlazzi CT, Giugliano E, Surace C, Anelli L, Rege-Cambrin G et al. A 76 Kb duplicon maps close to the BCR gene on chromosome 22 and the ABL gene on chromosome 9: Possible involvement in the genesis of the philadelphia chromosome translocation. Proc Natl Acad Sci USA 2002; 99: 9882-9887.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 9882-9887
    • Saglio, G.1    Storlazzi, C.T.2    Giugliano, E.3    Surace, C.4    Anelli, L.5    Rege-Cambrin, G.6
  • 27
    • 0035071955 scopus 로고    scopus 로고
    • Olfactory receptor-gene clusters, genomic-inversion polymorphisms, and common chromosome rearrangements
    • Giglio S, Broman KW, Matsumoto N, Calvari V, Gimelli G, Neumann T et al. Olfactory receptor-gene clusters, genomic-inversion polymorphisms, and common chromosome rearrangements. Am J Hum Genet 2001; 68: 874-883.
    • (2001) Am J Hum Genet , vol.68 , pp. 874-883
    • Giglio, S.1    Broman, K.W.2    Matsumoto, N.3    Calvari, V.4    Gimelli, G.5    Neumann, T.6
  • 28
    • 0036071427 scopus 로고    scopus 로고
    • Heterozygous submicroscopic inversions involving olfactory receptor-gene clusters mediate the recurrent t(4;8)(p16;p23) translocation
    • Giglio S, Calvari V, gregato G, Gimelli G, Camanini S, Giorda R et al. Heterozygous submicroscopic inversions involving olfactory receptor-gene clusters mediate the recurrent t(4;8)(p16;p23) translocation. Am J Hum Genet 2002; 71: 276-285.
    • (2002) Am J Hum Genet , vol.71 , pp. 276-285
    • Giglio, S.1    Calvari, V.2    Gregato, G.3    Gimelli, G.4    Camanini, S.5    Giorda, R.6
  • 29
    • 0035011834 scopus 로고    scopus 로고
    • Alteration of chromosome arm 6p is characteristic of primary mediastinal B-cell lymphoma, as identified by genome-wide allelotyping
    • Rigaud G, Moore PS, Taruscio D, Scardoni M, Montresor M, Menestrina F et al. Alteration of chromosome arm 6p is characteristic of primary mediastinal B-cell lymphoma, as identified by genome-wide allelotyping. Genes Chromosomes Cancer 2001; 31: 191-195.
    • (2001) Genes Chromosomes Cancer , vol.31 , pp. 191-195
    • Rigaud, G.1    Moore, P.S.2    Taruscio, D.3    Scardoni, M.4    Montresor, M.5    Menestrina, F.6
  • 31
    • 0031974484 scopus 로고    scopus 로고
    • Comparison of DNA copy number changes in malignant mesothelioma, adenocarcinoma and large-cell anaplastic carcinoma of the lung
    • Bjorkqvist AM, Tammilehto L, Nordling S, Nu'minen M, Anttilla S, Mattson K et al. Comparison of DNA copy number changes in malignant mesothelioma, adenocarcinoma and large-cell anaplastic carcinoma of the lung. Br J Cancer 1998; 77: 260-269.
    • (1998) Br J Cancer , vol.77 , pp. 260-269
    • Bjorkqvist, A.M.1    Tammilehto, L.2    Nordling, S.3    Nu'minen, M.4    Anttilla, S.5    Mattson, K.6
  • 32
    • 19944430329 scopus 로고    scopus 로고
    • Candidate genes in breast cancer revealed by microarray-based comparative genomic hybridization of archived tissue
    • Nessling M, Richter K, Schwaenen C, Roerig P, Wrobel G, Wessendorf S et al. Candidate genes in breast cancer revealed by microarray-based comparative genomic hybridization of archived tissue. Cancer Res 2005; 65: 439-447.
    • (2005) Cancer Res , vol.65 , pp. 439-447
    • Nessling, M.1    Richter, K.2    Schwaenen, C.3    Roerig, P.4    Wrobel, G.5    Wessendorf, S.6
  • 33
    • 0036329794 scopus 로고    scopus 로고
    • Genetic alterations in epithelial ovarian tumors analyzed by comparative genomic hybridization
    • Hauptmann S, Denkert C, Koch I, Petersen S, Scluns K, Reles A et al. Genetic alterations in epithelial ovarian tumors analyzed by comparative genomic hybridization. Hum Pathol 2002; 33: 632-641.
    • (2002) Hum Pathol , vol.33 , pp. 632-641
    • Hauptmann, S.1    Denkert, C.2    Koch, I.3    Petersen, S.4    Scluns, K.5    Reles, A.6
  • 34
    • 0036170837 scopus 로고    scopus 로고
    • Genomic amplification in retinoblastoma narrowed to 0.6 mega-base on chromosome 6p containing a kinesin-like gene, RBKIN
    • Chen D, Pajovic S, Duckett A, Brown VD, Squire JA, Gallie BL. Genomic amplification in retinoblastoma narrowed to 0.6 mega-base on chromosome 6p containing a kinesin-like gene, RBKIN. Cancer Res 2002; 62: 967-971.
    • (2002) Cancer Res , vol.62 , pp. 967-971
    • Chen, D.1    Pajovic, S.2    Duckett, A.3    Brown, V.D.4    Squire, J.A.5    Gallie, B.L.6
  • 35
    • 0035146240 scopus 로고    scopus 로고
    • Concomitant loss of chromosome 3 and whole arm losses and gains of chromosome 1, 6, or 8 in metastasizing primary uveal melanoma
    • Aalto Y, Eriksson L, Seregard S, Larsson O, Knuutila S. Concomitant loss of chromosome 3 and whole arm losses and gains of chromosome 1, 6, or 8 in metastasizing primary uveal melanoma. Invest Ophthalmol Vis Sci 2001; 42: 313-317.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 313-317
    • Aalto, Y.1    Eriksson, L.2    Seregard, S.3    Larsson, O.4    Knuutila, S.5
  • 36
    • 4243052846 scopus 로고    scopus 로고
    • Translocations involving 6p22 in acute myeloid leukaemia at relapse: Breakpoint characterization using microarray-based comparative genomic hybridization
    • Tchinda J, Dijkhuizen T, van der Vlies P, Kok K, Horst J. Translocations involving 6p22 in acute myeloid leukaemia at relapse: Breakpoint characterization using microarray-based comparative genomic hybridization. Br J Haematol 2004; 126: 495-500.
    • (2004) Br J Haematol , vol.126 , pp. 495-500
    • Tchinda, J.1    Dijkhuizen, T.2    van der Vlies, P.3    Kok, K.4    Horst, J.5
  • 38
    • 0037108434 scopus 로고    scopus 로고
    • Overexpression of FKBP51 in idiopathic myelofibrosis regulates the growth factor independence of megakaryocyte progenitors
    • Giraudier S, Chagraoui H, Komura E, Barnache S, Blanchet B, LeCouedic JP et al. Overexpression of FKBP51 in idiopathic myelofibrosis regulates the growth factor independence of megakaryocyte progenitors. Blood 2002; 100: 2932-2940.
    • (2002) Blood , vol.100 , pp. 2932-2940
    • Giraudier, S.1    Chagraoui, H.2    Komura, E.3    Barnache, S.4    Blanchet, B.5    LeCouedic, J.P.6
  • 39
    • 0035057424 scopus 로고    scopus 로고
    • Duplication or amplification of chromosome 11q23, including the unrearranged MLL gene, is a recurrent abnormality in therapy-related MDS and AML, and is closely related to mutation of the TP53 gene and to previous therapy with alkylating agents
    • Andersen MK, Christiansen DH, Kirchhoff M, Pedersen-Bjergaard J. Duplication or amplification of chromosome 11q23, including the unrearranged MLL gene, is a recurrent abnormality in therapy-related MDS and AML, and is closely related to mutation of the TP53 gene and to previous therapy with alkylating agents. Genes Chromosomes Cancer 2001; 31: 337-349.
    • (2001) Genes Chromosomes Cancer , vol.31 , pp. 337-349
    • Andersen, M.K.1    Christiansen, D.H.2    Kirchhoff, M.3    Pedersen-Bjergaard, J.4
  • 40
    • 13544273521 scopus 로고    scopus 로고
    • Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML
    • Andersen MK, Christiansen DH, Pedersen-Bjegaard J. Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML. Leukemia 2005; 19: 197-200.
    • (2005) Leukemia , vol.19 , pp. 197-200
    • Andersen, M.K.1    Christiansen, D.H.2    Pedersen-Bjegaard, J.3


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