Interpretation of the complex karyotype and identification of a new 6p amplicon by integrated comparative genomic hybridization and fluorescence in situ hybridization on the U937-I cell line

Cancer Genetics and Cytogenetics

Volumn 135, Issue 1, 2002, Pages 28-34

  Matteucci, Caterina ^a   La Starza, Roberta ^a   Crescenzi, Barbara ^a   Falzetti, Daniela ^a   Romoli, Silvia ^a   Emiliani, Carla ^b   Orlacchio, Aldo ^b   Marynen, Peter ^a   Martelli, Massimo F ^a   Mecucci, Cristina ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMPLICON; ARTICLE; CANCER GENETICS; CELL LINE; CHROMOSOME 1; COMPARATIVE GENOMIC HYBRIDIZATION; CYTOGENETICS; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; HISTIOCYTIC LYMPHOMA; HUMAN; HUMAN CELL; KARYOTYPE; PRIORITY JOURNAL;

ANEUPLOIDY; CHROMOSOMES, HUMAN; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 6; GENE AMPLIFICATION; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; NUCLEIC ACID HYBRIDIZATION; U937 CELLS;

EID: 18444390564     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(01)00637-9     Document Type: Article

References (18)

1. Establishment and characterization of a human histiocytic lymphoma cell line (U-937)
2. Karyotypic analysis of the human monoblastic cell line U937
3. The characterization of high resolution G-banded chromosomes of man
4. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors
5. Optimization of comparative genomic hybridization using fluorochrome conjugated to dCTP and dUTP nucleotides
6. Chromosomal breakpoints and changes in DNA copy number in refractory acute myeloid leukemia
7. Successful use of the same slide for consecutive fluorescence in situ hybridization (FISH) experiments
8. The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 chlatrin assembly protein family
9. Fluorescence in situ hybridization analysis of chromosome 1 abnormalities in hematopoietic disorders; rearrangements of DNA satellite II and new recurrent translocations
10. Regions of juxtaposition in unbalanced 1q rearrangements of malignant hemopathies
11. DNA copy number amplifications in human neoplasms
12. High incidence of chromosomal imbalances and gene amplifications in classical follicular variant of follicle center lymphoma
13. Characteristic pattern of chromosomal gains and losses in marginal zone B cell lymphoma detected by comparative genomic hybridization
14. Detection of amplification of a chromosomal fragment at 6p21 including the cyclin D3 gene in a glioblastoma cell line by arbitrarily primed polymerase chain reaction
15. Levels of cyclin D1 and D3 in malignant melanoma; deregulated cyclin D3 expression is associated with poor clinical outcome in superficial melanoma
16. Comparative genomic hybridization; a comparison with molecular and cytogenetic analysis
17. Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization