Synthesis and 32P-postlabeling/high-performance liquid chromatography separation of diastereomeric 1,N2-(1,3.Propano)-2'-deoxyguanosine 3'- phosphate adducts formed from 4-hydroxy-2-nonenal

Chemical Research in Toxicology

Volumn 10, Issue 11, 1997, Pages 1259-1265

  Yi, Ping ^a   Zhan, DeJin ^a   Samokyszyn, Victor M ^b   Doerge, Daniel R ^a   Fu, Peter P ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; 1,N(2) (1,3 PROPANO) 2' DEOXYGUANOSINE; 1,N(2)-(1,3-PROPANO)-2'-DEOXYGUANOSINE; 4-HYDROXY-2-NONENAL; ALDEHYDE; CYSTEINE PROTEINASE INHIBITOR; DEOXYGUANOSINE; DIAGNOSTIC AGENT; DRUG DERIVATIVE; MUTAGENIC AGENT; PHOSPHORUS;

ARTICLE; CROSS LINKING; CYTOTOXICITY; DEPHOSPHORYLATION; DNA ADDUCT; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LABELING INDEX; LIPID PEROXIDATION; MUTAGENICITY; NONHUMAN; PROTEIN DNA INTERACTION; CHEMISTRY; CONFORMATION; ISOLATION AND PURIFICATION; ISOTOPE LABELING; NUCLEAR MAGNETIC RESONANCE IMAGING; STEREOISOMERISM; SYNTHESIS; THIN LAYER CHROMATOGRAPHY; ULTRAVIOLET SPECTROPHOTOMETRY;

ALDEHYDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; CYSTEINE PROTEINASE INHIBITORS; DEOXYGUANOSINE; DNA ADDUCTS; ISOTOPE LABELING; MAGNETIC RESONANCE IMAGING; MOLECULAR CONFORMATION; MUTAGENS; PHOSPHORUS RADIOISOTOPES; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM;

EID: 0030608833     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx970100r     Document Type: Article

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