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Volumn 16, Issue 5, 2003, Pages 265-271

Cellular utake of the Tat peptide: An endocytosis mechanism following ionic interactions

Author keywords

Cell uptake; Cell penetrating peptide; Fixation; Tat peptide

Indexed keywords

ADENOVIRIDAE;

EID: 0141907727     PISSN: 09523499     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmr.636     Document Type: Conference Paper
Times cited : (153)

References (50)
  • 1
    • 0035157971 scopus 로고    scopus 로고
    • Activation of Rhoa and ROCK are essential for detachment of migrating leukocytes
    • Alblas J, Ulfman L, Hordijk P, Koenderman L. 2001. Activation of Rhoa and ROCK are essential for detachment of migrating leukocytes. Mol. Biol. Cell 12(7): 2137-2145.
    • (2001) Mol. Biol. Cell , vol.12 , Issue.7 , pp. 2137-2145
    • Alblas, J.1    Ulfman, L.2    Hordijk, P.3    Koenderman, L.4
  • 2
    • 0026545612 scopus 로고
    • Potocytosis: Sequestration and transport of small molecules by caveolae
    • Anderson RG, Kamen BA, Rothberg KG, Lacey SW. 1992. Potocytosis: sequestration and transport of small molecules by caveolae. Science 255(5043): 410-411.
    • (1992) Science , vol.255 , Issue.5043 , pp. 410-411
    • Anderson, R.G.1    Kamen, B.A.2    Rothberg, K.G.3    Lacey, S.W.4
  • 4
    • 0034012647 scopus 로고    scopus 로고
    • Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates
    • Astriab-Fisher A, Sergueev DS, Fisher M, Shaw BR, Juliano RL. 2000. Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates. Biochem. Pharmac. 60(1): 83-90.
    • (2000) Biochem. Pharmac. , vol.60 , Issue.1 , pp. 83-90
    • Astriab-Fisher, A.1    Sergueev, D.S.2    Fisher, M.3    Shaw, B.R.4    Juliano, R.L.5
  • 5
    • 0036298282 scopus 로고    scopus 로고
    • Conjugates of antisense oligonucleotides with the Tat and antennapedia cell-penetrating peptides: Effects on cellular uptake, binding to target sequences, and biologic actions
    • Astriab-Fisher A, Sergueev D, Fisher M, Shaw BR, Juliano RL. 2002. Conjugates of antisense oligonucleotides with the Tat and antennapedia cell-penetrating peptides: effects on cellular uptake, binding to target sequences, and biologic actions. Pharm. Res. 19(6): 744-754.
    • (2002) Pharm. Res. , vol.19 , Issue.6 , pp. 744-754
    • Astriab-Fisher, A.1    Sergueev, D.2    Fisher, M.3    Shaw, B.R.4    Juliano, R.L.5
  • 6
    • 0035152487 scopus 로고    scopus 로고
    • Cell-permeable peptide inhibitors of JNK: Novel blockers of beta-cell death
    • Bonny C, Oberson A, Negri S, Sauser C, Schorderet DF. 2001. Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death. Diabetes 50(1): 77-82.
    • (2001) Diabetes , vol.50 , Issue.1 , pp. 77-82
    • Bonny, C.1    Oberson, A.2    Negri, S.3    Sauser, C.4    Schorderet, D.F.5
  • 7
    • 0028239908 scopus 로고
    • The third helix of the Antennapedia homeodomain translocates through biological membranes
    • Derossi D, Joliot AH, Chassaing G, Prochiantz A. 1994. The third helix of the Antennapedia homeodomain translocates through biological membranes. J. Biol. Chem. 269(14): 10444-10450.
    • (1994) J. Biol. Chem. , vol.269 , Issue.14 , pp. 10444-10450
    • Derossi, D.1    Joliot, A.H.2    Chassaing, G.3    Prochiantz, A.4
  • 8
    • 0029982569 scopus 로고    scopus 로고
    • Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent
    • Derossi D, Calvet S, Trembleau A, Brunissen A, Chassaing G, Prochiantz A. 1996. Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent. J. Biol. Chem. 271(30): 18188-18193.
    • (1996) J. Biol. Chem. , vol.271 , Issue.30 , pp. 18188-18193
    • Derossi, D.1    Calvet, S.2    Trembleau, A.3    Brunissen, A.4    Chassaing, G.5    Prochiantz, A.6
  • 9
    • 0031984072 scopus 로고    scopus 로고
    • Trojan peptides: The penetratin system for intracellular delivery
    • Derossi D, Chassaing G, Prochiantz A. 1998. Trojan peptides: the penetratin system for intracellular delivery. Trends Cell Biol. 8(2): 84-87.
    • (1998) Trends Cell Biol. , vol.8 , Issue.2 , pp. 84-87
    • Derossi, D.1    Chassaing, G.2    Prochiantz, A.3
  • 10
    • 0036892612 scopus 로고    scopus 로고
    • Endocytosis is a critical step in entry of subgroup B avian leukosis viruses
    • Diaz-Griffero F, Hoschander SA, Brojatsch J. 2002. Endocytosis is a critical step in entry of subgroup B avian leukosis viruses. J. Virol. 76(24): 12866-12876.
    • (2002) J. Virol. , vol.76 , Issue.24 , pp. 12866-12876
    • Diaz-Griffero, F.1    Hoschander, S.A.2    Brojatsch, J.3
  • 11
    • 0034687854 scopus 로고    scopus 로고
    • Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase 1alpha inhibit NO-induced cerebral dilation
    • Dostmann WR, Taylor MS, Nickl CK, Brayden JE, Frank R, Tegge WJ. 2000. Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase 1alpha inhibit NO-induced cerebral dilation. Proc. Natl Acad. Sci. USA 97(26): 14772-14777.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , Issue.26 , pp. 14772-14777
    • Dostmann, W.R.1    Taylor, M.S.2    Nickl, C.K.3    Brayden, J.E.4    Frank, R.5    Tegge, W.J.6
  • 12
    • 0035852797 scopus 로고    scopus 로고
    • Translocation of the pAntp peptide and its amphipathic analogue AP-2AL
    • Drin G, Demene H, Temsamani J, Brasseur R. 2001. Translocation of the pAntp peptide and its amphipathic analogue AP-2AL. Biochemistry 40(6): 1824-1834.
    • (2001) Biochemistry , vol.40 , Issue.6 , pp. 1824-1834
    • Drin, G.1    Demene, H.2    Temsamani, J.3    Brasseur, R.4
  • 15
    • 0036804013 scopus 로고    scopus 로고
    • Arginine-rich peptides: Potential for intracellular delivery of macromolecules and the mystery of the translocation mechanisms
    • Futaki S. 2002. Arginine-rich peptides: potential for intracellular delivery of macromolecules and the mystery of the translocation mechanisms. Int. J. Pharm. 245(1-2): 1-7.
    • (2002) Int. J. Pharm. , vol.245 , Issue.1-2 , pp. 1-7
    • Futaki, S.1
  • 16
    • 0035937124 scopus 로고    scopus 로고
    • Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery
    • Futaki S, Suzuki T, Ohashi W, Yagami T, Tanaka S, Ueda K, Sugiura Y. 2001. Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery. J. Biol. Chem. 276(8): 5836-5840.
    • (2001) J. Biol. Chem. , vol.276 , Issue.8 , pp. 5836-5840
    • Futaki, S.1    Suzuki, T.2    Ohashi, W.3    Yagami, T.4    Tanaka, S.5    Ueda, K.6    Sugiura, Y.7
  • 17
    • 0037172801 scopus 로고    scopus 로고
    • Translocation of branched-chain arginine peptides through cell membranes: Flexibility in the spatial disposition of positive charges in membrane-permeable peptides
    • Futaki S, Nakase I, Suzuki T, Youjun Z, Sugiura Y. 2002. Translocation of branched-chain arginine peptides through cell membranes: flexibility in the spatial disposition of positive charges in membrane-permeable peptides. Biochemistry 41(25): 7925-7930.
    • (2002) Biochemistry , vol.41 , Issue.25 , pp. 7925-7930
    • Futaki, S.1    Nakase, I.2    Suzuki, T.3    Youjun, Z.4    Sugiura, Y.5
  • 18
    • 0037349932 scopus 로고    scopus 로고
    • Cell-permeable peptides improve cellular uptake and therapeutic gene delivery of replication-deficient viruses in cells and in vivo
    • Gratton JP, Yu J, Griffith JW, Babbitt RW, Scotland RS, Hickey R, Giordano FJ, Sessa WC. 2003. Cell-permeable peptides improve cellular uptake and therapeutic gene delivery of replication-deficient viruses in cells and in vivo. Nat. Med. 9(3): 357-363.
    • (2003) Nat. Med. , vol.9 , Issue.3 , pp. 357-363
    • Gratton, J.P.1    Yu, J.2    Griffith, J.W.3    Babbitt, R.W.4    Scotland, R.S.5    Hickey, R.6    Giordano, F.J.7    Sessa, W.C.8
  • 19
    • 0034794191 scopus 로고    scopus 로고
    • Epigenetic regulation of gene structure and function with a cell- Permeable Cre recombinase
    • Jo D, Nashabi A, Doxsee C, Lin Q, Unutmaz D, Chen J, Ruley HE. 2001. Epigenetic regulation of gene structure and function with a cell- permeable Cre recombinase. Nat. Biotechnol. 19(10): 929-933.
    • (2001) Nat. Biotechnol. , vol.19 , Issue.10 , pp. 929-933
    • Jo, D.1    Nashabi, A.2    Doxsee, C.3    Lin, Q.4    Unutmaz, D.5    Chen, J.6    Ruley, H.E.7
  • 20
    • 0037474028 scopus 로고    scopus 로고
    • No entry for Tat(44-57) into liposomes and intact MDCK cells: Novel approach to study membrane permeation oc cell-penetrating peptides
    • Kramer SD, Wunderli-Allenspach H. 2003. No entry for Tat(44-57) into liposomes and intact MDCK cells: novel approach to study membrane permeation oc cell-penetrating peptides. Biochem. Biophys. Acta 1609: 161-169.
    • (2003) Biochem. Biophys. Acta , vol.1609 , pp. 161-169
    • Kramer, S.D.1    Wunderli-Allenspach, H.2
  • 21
    • 0034711454 scopus 로고    scopus 로고
    • Transduction of Cu,Zn-superoxide dismutase mediated by an HIV-1 Tat protein basic domain into mammalian cells
    • Kwon HY, Eum WS, Jang HW, Kang JH, Ryu J, Ryong Lee B, Jin LH, Park J, Choi SY. 2000. Transduction of Cu,Zn-superoxide dismutase mediated by an HIV-1 Tat protein basic domain into mammalian cells. FEBS Lett. 485(2-3): 163-167.
    • (2000) FEBS Lett. , vol.485 , Issue.2-3 , pp. 163-167
    • Kwon, H.Y.1    Eum, W.S.2    Jang, H.W.3    Kang, J.H.4    Ryu, J.5    Ryong Lee, B.6    Jin, L.H.7    Park, J.8    Choi, S.Y.9
  • 22
    • 0036846565 scopus 로고    scopus 로고
    • Full-length proteins attached to the HIV tat protein transduction domain are neither transduced between cells, nor exhibit enhanced immunogenicity
    • Leifert JA, Harkins S, Whitton JL. 2002. Full-length proteins attached to the HIV tat protein transduction domain are neither transduced between cells, nor exhibit enhanced immunogenicity. Gene Ther. 9(21): 1422-1428.
    • (2002) Gene Ther. , vol.9 , Issue.21 , pp. 1422-1428
    • Leifert, J.A.1    Harkins, S.2    Whitton, J.L.3
  • 23
    • 0025398291 scopus 로고
    • Biological activity of oligonucleotide-poly(L-lysine) conjugates: Mechanism of cell uptake
    • Leonetti JP, Degols G, Lebleu B. 1990. Biological activity of oligonucleotide-poly(L-lysine) conjugates: mechanism of cell uptake. Bioconjug. Chem. 1(2): 149-153.
    • (1990) Bioconjug. Chem. , vol.1 , Issue.2 , pp. 149-153
    • Leonetti, J.P.1    Degols, G.2    Lebleu, B.3
  • 24
    • 0034006169 scopus 로고    scopus 로고
    • Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
    • Lewin M, Carlesso N, Tung CH, Tang XW, Cory D, Scadden DT, Weissleder R. 2000. Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat. Biotechnol. 18(4): 410-414.
    • (2000) Nat. Biotechnol. , vol.18 , Issue.4 , pp. 410-414
    • Lewin, M.1    Carlesso, N.2    Tung, C.H.3    Tang, X.W.4    Cory, D.5    Scadden, D.T.6    Weissleder, R.7
  • 25
    • 0036792527 scopus 로고    scopus 로고
    • Peptide-mediated cell delivery: Application in protein target validation
    • Lindsay MA. 2002. Peptide-mediated cell delivery: application in protein target validation. Curr. Opin. Pharmac. 2(5): 587-594.
    • (2002) Curr. Opin. Pharmac. , vol.2 , Issue.5 , pp. 587-594
    • Lindsay, M.A.1
  • 26
    • 0036289650 scopus 로고    scopus 로고
    • Positively charged DNA-binding proteins cause apparent cell membrane translocation
    • Lundberg M, Johansson M. 2002. Positively charged DNA-binding proteins cause apparent cell membrane translocation. Biochem. Biophys. Res. Commun. 291(2): 367-371.
    • (2002) Biochem. Biophys. Res. Commun. , vol.291 , Issue.2 , pp. 367-371
    • Lundberg, M.1    Johansson, M.2
  • 27
    • 0025797055 scopus 로고
    • Endocytosis and targeting of exogenous HIV-1 Tat protein
    • Mann DA, Frankel AD. 1991. Endocytosis and targeting of exogenous HIV-1 Tat protein. Embo J. 10(7): 1733-1739.
    • (1991) Embo J. , vol.10 , Issue.7 , pp. 1733-1739
    • Mann, D.A.1    Frankel, A.D.2
  • 28
    • 0033794501 scopus 로고    scopus 로고
    • Polyarginine enters cells more efficiently than other polycationic homopolymers
    • Mitchell DJ, Kim DT, Steinman L, Fathman CG, Rothbard JB. 2000. Polyarginine enters cells more efficiently than other polycationic homopolymers. J. Pept. Res. 56(5): 318-325.
    • (2000) J. Pept. Res. , vol.56 , Issue.5 , pp. 318-325
    • Mitchell, D.J.1    Kim, D.T.2    Steinman, L.3    Fathman, C.G.4    Rothbard, J.B.5
  • 30
    • 0037007121 scopus 로고    scopus 로고
    • Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: A tool for efficient genetic engineering of mammalian genomes
    • Peitz M, Pfannkuche K, Rajewsky K, Edenhofer F. 2002. Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes. Proc. Natl Acad. Sci. USA 99(7): 4489-4494.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , Issue.7 , pp. 4489-4494
    • Peitz, M.1    Pfannkuche, K.2    Rajewsky, K.3    Edenhofer, F.4
  • 31
    • 0033040441 scopus 로고    scopus 로고
    • Intracellular localization of oligonucleotides: Influence of fixative protocols
    • Pichon C, Monsigny M, Roche AC. 1999. Intracellular localization of oligonucleotides: influence of fixative protocols. Anti-sense Nucl. Acid Drug Dev. 9(1): 89-93.
    • (1999) Anti-sense Nucl. Acid Drug Dev. , vol.9 , Issue.1 , pp. 89-93
    • Pichon, C.1    Monsigny, M.2    Roche, A.C.3
  • 32
    • 0030273590 scopus 로고    scopus 로고
    • Getting hydrophilic compounds into cells: Lessons from homeopeptides
    • Prochiantz A. 1996. Getting hydrophilic compounds into cells: lessons from homeopeptides. Curr. Opin. Neurobiol. 6(5): 629-634.
    • (1996) Curr. Opin. Neurobiol. , vol.6 , Issue.5 , pp. 629-634
    • Prochiantz, A.1
  • 34
    • 0037103242 scopus 로고    scopus 로고
    • Arginine-rich molecular transporters for drug delivery: Role of backbone spacing in cellular uptake
    • Rothbard JB, Kreider E, VanDeusen CL, Wright L, Wylie BL, Wender PA. 2002. Arginine-rich molecular transporters for drug delivery: role of backbone spacing in cellular uptake. J. Med. Chem. 45(17): 3612-3618.
    • (2002) J. Med. Chem. , vol.45 , Issue.17 , pp. 3612-3618
    • Rothbard, J.B.1    Kreider, E.2    VanDeusen, C.L.3    Wright, L.4    Wylie, B.L.5    Wender, P.A.6
  • 37
    • 0033520487 scopus 로고    scopus 로고
    • In vivo protein transduction: Delivery of a biologically active protein into the mouse
    • Schwarze SR, Ho A, Vocero-Akbani A, Dowdy SF. 1999. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 285(5433): 1569-1572.
    • (1999) Science , vol.285 , Issue.5433 , pp. 1569-1572
    • Schwarze, S.R.1    Ho, A.2    Vocero-Akbani, A.3    Dowdy, S.F.4
  • 38
    • 0036159271 scopus 로고    scopus 로고
    • Different mechanisms for cellular internalization of the HIV-1 Tatderived cell penetrating peptide and recombinant proteins fused to Tat
    • Silhol M, Tyagi M, Giacca M, Lebleu B, Vives E. 2002. Different mechanisms for cellular internalization of the HIV-1 Tatderived cell penetrating peptide and recombinant proteins fused to Tat. Eur. J. Biochem. 269(2): 494-501.
    • (2002) Eur. J. Biochem. , vol.269 , Issue.2 , pp. 494-501
    • Silhol, M.1    Tyagi, M.2    Giacca, M.3    Lebleu, B.4    Vives, E.5
  • 39
    • 0037169486 scopus 로고    scopus 로고
    • Possible existence of common internalization mechanisms among arginine-rich peptides
    • Suzuki T, Futaki S, Niwa M, Tanaka S, Ueda K, Sugiura Y. 2002. Possible existence of common internalization mechanisms among arginine-rich peptides. J. Biol. Chem. 277(4): 2437-2443.
    • (2002) J. Biol. Chem. , vol.277 , Issue.4 , pp. 2437-2443
    • Suzuki, T.1    Futaki, S.2    Niwa, M.3    Tanaka, S.4    Ueda, K.5    Sugiura, Y.6
  • 40
    • 0028963094 scopus 로고
    • Maturation of early endosomes and vesicular traffic to lysosomes in relation to membrane recycling
    • Thilo L, Stroud E, Haylett T. 1995. Maturation of early endosomes and vesicular traffic to lysosomes in relation to membrane recycling. J. Cell Sci. 108: 1791-1803.
    • (1995) J. Cell Sci. , vol.108 , pp. 1791-1803
    • Thilo, L.1    Stroud, E.2    Haylett, T.3
  • 41
    • 0034613057 scopus 로고    scopus 로고
    • The antennapedia peptide penetratin translocates across lipid bilayers - The first direct observation
    • Thoren PE, Persson D, Karlsson M, Norden B. 2000. The antennapedia peptide penetratin translocates across lipid bilayers - the first direct observation. FEBS Lett. 482(3): 265-268.
    • (2000) FEBS Lett. , vol.482 , Issue.3 , pp. 265-268
    • Thoren, P.E.1    Persson, D.2    Karlsson, M.3    Norden, B.4
  • 42
    • 0035902477 scopus 로고    scopus 로고
    • TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors
    • Torchilin VP, Rammohan R, Weissig V, Levchenko TS. 2001. TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors. Proc. Natl Acad. Sci. USA 98(15): 8786-8791.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.15 , pp. 8786-8791
    • Torchilin, V.P.1    Rammohan, R.2    Weissig, V.3    Levchenko, T.S.4
  • 44
    • 0035793619 scopus 로고    scopus 로고
    • Internalization of HIV-1 tat requires cell surface heparan sulfate proteoglycans
    • Tyagi M, Rusnati M, Presta M, Giacca M. 2001. Internalization of HIV-1 tat requires cell surface heparan sulfate proteoglycans. J. Biol. Chem. 276(5): 3254-3261.
    • (2001) J. Biol. Chem. , vol.276 , Issue.5 , pp. 3254-3261
    • Tyagi, M.1    Rusnati, M.2    Presta, M.3    Giacca, M.4
  • 46
    • 0021330443 scopus 로고
    • Antigens associated with a human lung adenocarcinoma defined by monoclonal antibodies
    • Varki NM, Reisfeld RA, Walker LE. 1984. Antigens associated with a human lung adenocarcinoma defined by monoclonal antibodies. Cancer Res. 44(2): 681-687.
    • (1984) Cancer Res. , vol.44 , Issue.2 , pp. 681-687
    • Varki, N.M.1    Reisfeld, R.A.2    Walker, L.E.3
  • 47
    • 0030904245 scopus 로고    scopus 로고
    • A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
    • Vives E, Brodin P, Lebleu B. 1997a. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J. Biol. Chem. 272(25): 16010-16017.
    • (1997) J. Biol. Chem. , vol.272 , Issue.25 , pp. 16010-16017
    • Vives, E.1    Brodin, P.2    Lebleu, B.3
  • 48
    • 0001610172 scopus 로고    scopus 로고
    • Structure activity relationship study of the plasma membrane translocating potential of a short peptide from HIV-1 Tat protein
    • Vives E, Granier C, Prevot P, Lebleu B. 1997b. Structure activity relationship study of the plasma membrane translocating potential of a short peptide from HIV-1 Tat protein. Lett. Peptide Sci. 4: 429-436.
    • (1997) Lett. Peptide Sci. , vol.4 , pp. 429-436
    • Vives, E.1    Granier, C.2    Prevot, P.3    Lebleu, B.4
  • 49
    • 0034700141 scopus 로고    scopus 로고
    • The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
    • Wender PA, Mitchell DJ, Pattabiraman K, Pelkey ET, Steinman L, Rothbard JB. 2000. The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proc. Natl Acad. Sci. USA 97(24): 13003-13008.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , Issue.24 , pp. 13003-13008
    • Wender, P.A.1    Mitchell, D.J.2    Pattabiraman, K.3    Pelkey, E.T.4    Steinman, L.5    Rothbard, J.B.6
  • 50
    • 0029964866 scopus 로고    scopus 로고
    • Mechanism of oligonucleotide release from cationic liposomes
    • Zelphati O, Szoka FJ. 1996. Mechanism of oligonucleotide release from cationic liposomes. Proc. Natl Acad. Sci. USA 93(21): 11493-11498.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , Issue.21 , pp. 11493-11498
    • Zelphati, O.1    Szoka, F.J.2


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