Identification of formaldehyde-induced modifications in proteins: Reactions with insulin

Bioconjugate Chemistry

Volumn 17, Issue 3, 2006, Pages 815-822

  Metz, Bernard ^a,b,d   Kersten, Gideon F A ^a   Baart, Gino J E ^a   De Jong, Ad ^a   Meiring, Hugo ^a   Ten Hove, Jan ^a   Van Steenbergen, Mies J ^b   Hennink, Wim E ^b   Crommelin, Daan J A ^b   Jiskoot, Wim ^b,c  

^a NETHERLANDS VACCINE INSTITUTE   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

^d NONE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHEMICAL MODIFICATION; FORMALDEHYDE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROTEINS;

INSULIN MOLECULES; INTRAMOLECULAR CROSS-LINKS; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; METHYLENE BRIDGE; METHYLOL; PEPTIDE FRAGMENTS; PROTEIN REACTION; REACTIVE SITE; SCHIFF-BASE; SMALL PROTEINS;

INSULIN;

ARGININE; ASPARAGINE; CARBENE; FORMALDEHYDE; GLUTAMINE; GLYCINE; HISTIDINE; IMIDAZOLIDINONE; IMIDAZOLINE DERIVATIVE; INSULIN; LYSINE; METHYLOL DERIVATIVE; PROTEIN; SCHIFF BASE; TYROSINE; UNCLASSIFIED DRUG; VACCINE;

AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION KINETICS; INSULIN BINDING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROTEIN CROSS LINKING; PROTEIN IMMOBILIZATION; PROTEIN MODIFICATION; PROTEIN STABILITY;

EID: 33646908503     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc050340f     Document Type: Article

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