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Volumn 39, Issue 1, 2006, Pages 134-142

Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats

Author keywords

Arachidonic acid; Bone remodeling; Cyclooxygenase isoforms; Osteoclasts; Phospholipase A2

Indexed keywords

CYCLOOXYGENASE 2; PHOSPHOLIPASE A2;

EID: 33646877375     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2005.12.017     Document Type: Article
Times cited : (39)

References (59)
  • 1
    • 0029998565 scopus 로고    scopus 로고
    • Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo
    • Forwood M.R. Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo. J. Bone Miner. Res. 11 (1996) 1688-1693
    • (1996) J. Bone Miner. Res. , vol.11 , pp. 1688-1693
    • Forwood, M.R.1
  • 2
    • 0036551229 scopus 로고    scopus 로고
    • Suppression of prostaglandin synthesis with NS-398 has different effects on endocortical and periosteal bone formation induced by mechanical loading
    • Li J., Burr D.B., and Turner C.H. Suppression of prostaglandin synthesis with NS-398 has different effects on endocortical and periosteal bone formation induced by mechanical loading. Calcif. Tissue Int. 70 (2002) 320-329
    • (2002) Calcif. Tissue Int. , vol.70 , pp. 320-329
    • Li, J.1    Burr, D.B.2    Turner, C.H.3
  • 3
    • 0034066978 scopus 로고    scopus 로고
    • Prostaglandin G/H synthase-2 is required for maximal formation of osteoclast-like cells in culture
    • Okada Y., Lorenzo J.A., Freeman A.M., Tomita M., Morham S.G., Raisz L.G., et al. Prostaglandin G/H synthase-2 is required for maximal formation of osteoclast-like cells in culture. J. Clin. Invest. 105 (2000) 823-832
    • (2000) J. Clin. Invest. , vol.105 , pp. 823-832
    • Okada, Y.1    Lorenzo, J.A.2    Freeman, A.M.3    Tomita, M.4    Morham, S.G.5    Raisz, L.G.6
  • 4
    • 0030479496 scopus 로고    scopus 로고
    • Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2
    • Smith W.L., Garavito R.M., and DeWitt D.L. Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. J. Biol. Chem. 271 (1996) 33157-33160
    • (1996) J. Biol. Chem. , vol.271 , pp. 33157-33160
    • Smith, W.L.1    Garavito, R.M.2    DeWitt, D.L.3
  • 6
    • 16644382118 scopus 로고    scopus 로고
    • Regulatory mechanism and physiological role of cytosolic phospholipase A2
    • Hirabayashi T., Murayama T., and Shimizu T. Regulatory mechanism and physiological role of cytosolic phospholipase A2. Biol. Pharm. Bull. 27 (2004) 1168-1173
    • (2004) Biol. Pharm. Bull. , vol.27 , pp. 1168-1173
    • Hirabayashi, T.1    Murayama, T.2    Shimizu, T.3
  • 7
    • 0029917935 scopus 로고    scopus 로고
    • Interleukin-4 inhibits prostaglandin G/H synthase-2 and cytosolic phospholipase A2 induction in neonatal mouse parietal bone cultures
    • Kawaguchi H., Nemoto K., Raisz L.G., Harrison J.R., Voznesensky O.S., Alander C.B., et al. Interleukin-4 inhibits prostaglandin G/H synthase-2 and cytosolic phospholipase A2 induction in neonatal mouse parietal bone cultures. J. Bone Miner. Res. 11 (1996) 358-366
    • (1996) J. Bone Miner. Res. , vol.11 , pp. 358-366
    • Kawaguchi, H.1    Nemoto, K.2    Raisz, L.G.3    Harrison, J.R.4    Voznesensky, O.S.5    Alander, C.B.6
  • 8
    • 0029113851 scopus 로고
    • Ovariectomy enhances and estrogen replacement inhibits the activity of bone marrow factors that stimulate prostaglandin production in cultured mouse calvariae
    • Kawaguchi H., Pilbeam C.C., Vargas S.J., Morse E.E., Lorenzo J.A., and Raisz L.G. Ovariectomy enhances and estrogen replacement inhibits the activity of bone marrow factors that stimulate prostaglandin production in cultured mouse calvariae. J. Clin. Invest. 96 (1995) 539-548
    • (1995) J. Clin. Invest. , vol.96 , pp. 539-548
    • Kawaguchi, H.1    Pilbeam, C.C.2    Vargas, S.J.3    Morse, E.E.4    Lorenzo, J.A.5    Raisz, L.G.6
  • 9
    • 0033941227 scopus 로고    scopus 로고
    • Arachidonic acid for loading induced prostacyclin and prostaglandin E2 release from osteoblasts and osteocytes is derived from the activities of different forms of phospholipase A2
    • Rawlinson S.C.F., Wheeler-Jones C.P.D., and Lanyon L.E. Arachidonic acid for loading induced prostacyclin and prostaglandin E2 release from osteoblasts and osteocytes is derived from the activities of different forms of phospholipase A2. Bone 27 (2000) 241-247
    • (2000) Bone , vol.27 , pp. 241-247
    • Rawlinson, S.C.F.1    Wheeler-Jones, C.P.D.2    Lanyon, L.E.3
  • 10
    • 0026010116 scopus 로고
    • Interleukin-1 alpha stimulates the release of prostaglandin E2 and phospholipase A2 from fetal rat calvarial cells in vitro: relationship to bone nodule formation
    • Ellies L.G., Heersche J.N., Vadas P., Pruzanski W., Stefanski E., and Aubin J.E. Interleukin-1 alpha stimulates the release of prostaglandin E2 and phospholipase A2 from fetal rat calvarial cells in vitro: relationship to bone nodule formation. J. Bone Miner. Res. 6 (1991) 843-850
    • (1991) J. Bone Miner. Res. , vol.6 , pp. 843-850
    • Ellies, L.G.1    Heersche, J.N.2    Vadas, P.3    Pruzanski, W.4    Stefanski, E.5    Aubin, J.E.6
  • 11
    • 0032924033 scopus 로고    scopus 로고
    • Signal transduction pathways involved in fluid flow-induced PGE2 production by cultured osteocytes
    • Ajubi N.E., Klein-Nulend J., Alblas M.J., Burger E.H., and Nijweide P.J. Signal transduction pathways involved in fluid flow-induced PGE2 production by cultured osteocytes. Am. J. Physiol. 276 (1999) E171-E178
    • (1999) Am. J. Physiol. , vol.276
    • Ajubi, N.E.1    Klein-Nulend, J.2    Alblas, M.J.3    Burger, E.H.4    Nijweide, P.J.5
  • 12
    • 0034257927 scopus 로고    scopus 로고
    • Secretory phospholipase A2 receptor-mediated activation of cytosolic phospholipase A2 in murine bone marrow-derived mast cells
    • Fonteh A.N., Atsumi G., LaPorte T., and Chilton F.H. Secretory phospholipase A2 receptor-mediated activation of cytosolic phospholipase A2 in murine bone marrow-derived mast cells. J. Immunol. 165 (2000) 2773-2782
    • (2000) J. Immunol. , vol.165 , pp. 2773-2782
    • Fonteh, A.N.1    Atsumi, G.2    LaPorte, T.3    Chilton, F.H.4
  • 13
    • 0031689398 scopus 로고    scopus 로고
    • Mechanisms that account for the selective release of arachidonic acid from intact cells by secretory phospholipase A2
    • Fonteh A.N., Samet J.M., Surette M., Reed W., and Chilton F.H. Mechanisms that account for the selective release of arachidonic acid from intact cells by secretory phospholipase A2. Biochim. Biophys. Acta 1393 (1998) 253-266
    • (1998) Biochim. Biophys. Acta , vol.1393 , pp. 253-266
    • Fonteh, A.N.1    Samet, J.M.2    Surette, M.3    Reed, W.4    Chilton, F.H.5
  • 14
    • 1342324060 scopus 로고    scopus 로고
    • Cytosolic phospholipase A2alpha reigns supreme in arthritis and bone resorption
    • Bonventre J. Cytosolic phospholipase A2alpha reigns supreme in arthritis and bone resorption. Trends Immunol. 25 (2004) 116-119
    • (2004) Trends Immunol. , vol.25 , pp. 116-119
    • Bonventre, J.1
  • 15
    • 0038576289 scopus 로고    scopus 로고
    • An essential role of cytosolic phospholipase A2alpha in prostaglandin E2-mediated bone resorption associated with inflammation
    • Miyaura C., Inada M., Matsumoto C., Ohshiba T., Uozumi N., Shimizu T., and Ito A. An essential role of cytosolic phospholipase A2alpha in prostaglandin E2-mediated bone resorption associated with inflammation. J. Exp. Med. 197 (2003) 1303-1310
    • (2003) J. Exp. Med. , vol.197 , pp. 1303-1310
    • Miyaura, C.1    Inada, M.2    Matsumoto, C.3    Ohshiba, T.4    Uozumi, N.5    Shimizu, T.6    Ito, A.7
  • 17
    • 0031041082 scopus 로고    scopus 로고
    • Activation of cytosolic phospholipase A2 by platelet-derived growth factor is essential for cyclooxygenase-2-dependent prostaglandin E2 synthesis in mouse osteoblasts cultured with interleukin-1
    • Chen Q.R., Miyaura C., Higashi S., Murakami M., Kudo I., Saito S., et al. Activation of cytosolic phospholipase A2 by platelet-derived growth factor is essential for cyclooxygenase-2-dependent prostaglandin E2 synthesis in mouse osteoblasts cultured with interleukin-1. J. Biol. Chem. 272 (1997) 5952-5958
    • (1997) J. Biol. Chem. , vol.272 , pp. 5952-5958
    • Chen, Q.R.1    Miyaura, C.2    Higashi, S.3    Murakami, M.4    Kudo, I.5    Saito, S.6
  • 18
    • 0037468287 scopus 로고    scopus 로고
    • Neuronal damage by secretory phospholipase A2: modulation by cytosolic phospholipase A2, platelet-activating factor, and cyclooxygenase-2 in neuronal cells in culture
    • Kolko M., Rodriguez de Turco E.B., Diemer N.H., and Bazan N.G. Neuronal damage by secretory phospholipase A2: modulation by cytosolic phospholipase A2, platelet-activating factor, and cyclooxygenase-2 in neuronal cells in culture. Neurosci. Lett. 338 (2003) 164-168
    • (2003) Neurosci. Lett. , vol.338 , pp. 164-168
    • Kolko, M.1    Rodriguez de Turco, E.B.2    Diemer, N.H.3    Bazan, N.G.4
  • 19
    • 0028399309 scopus 로고
    • Role of inducible cyclooxygenase (COX-2) in inflammation
    • Seibert K., and Masferrer J.L. Role of inducible cyclooxygenase (COX-2) in inflammation. Receptor 4 (1994) 17-23
    • (1994) Receptor , vol.4 , pp. 17-23
    • Seibert, K.1    Masferrer, J.L.2
  • 20
    • 0029033219 scopus 로고
    • Pharmacology of a selective cyclooxygenase-2 inhibitor, L-745,337: a novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and nonhuman primate stomach
    • Chan C.C., Boyce S., Brideau C., Ford-Hutchinson A.W., Gordon R., Guay D., et al. Pharmacology of a selective cyclooxygenase-2 inhibitor, L-745,337: a novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and nonhuman primate stomach. J. Pharmacol. Exp. Ther. 274 (1995) 1531-1537
    • (1995) J. Pharmacol. Exp. Ther. , vol.274 , pp. 1531-1537
    • Chan, C.C.1    Boyce, S.2    Brideau, C.3    Ford-Hutchinson, A.W.4    Gordon, R.5    Guay, D.6
  • 21
    • 0029445471 scopus 로고
    • Effect of nonsteroidal antiinflammatory drugs on fracture healing: a laboratory study in rats
    • Altman R.D., Latta L.L., Keer R., Renfree K., Hornicek F.J., and Banovac K. Effect of nonsteroidal antiinflammatory drugs on fracture healing: a laboratory study in rats. J. Orthop. Trauma 9 (1995) 392-400
    • (1995) J. Orthop. Trauma , vol.9 , pp. 392-400
    • Altman, R.D.1    Latta, L.L.2    Keer, R.3    Renfree, K.4    Hornicek, F.J.5    Banovac, K.6
  • 22
    • 0035999429 scopus 로고    scopus 로고
    • Cyclo-oxygenase 2 function is essential for bone fracture healing
    • Simon A., Manigrasso M., and O'Connor J. Cyclo-oxygenase 2 function is essential for bone fracture healing. J. Bone Miner. Res. 17 (2002) 963-976
    • (2002) J. Bone Miner. Res. , vol.17 , pp. 963-976
    • Simon, A.1    Manigrasso, M.2    O'Connor, J.3
  • 23
    • 0036259278 scopus 로고    scopus 로고
    • Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair
    • Zhang X., Schwarz E.M., Young D.A., Puzas J.E., Rosier R.N., and O'Keefe R.J. Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. J. Clin. Invest. 109 (2002) 1405-1415
    • (2002) J. Clin. Invest. , vol.109 , pp. 1405-1415
    • Zhang, X.1    Schwarz, E.M.2    Young, D.A.3    Puzas, J.E.4    Rosier, R.N.5    O'Keefe, R.J.6
  • 24
    • 0029967465 scopus 로고    scopus 로고
    • Involvement of prostaglandin endoperoxide H synthase-2 in osteoclast-like cell formation induced by interleukin-1 beta
    • Sato T., Morita I., Sakaguchi K., Nakahama K.I., Smith W.L., Dewitt D.L., et al. Involvement of prostaglandin endoperoxide H synthase-2 in osteoclast-like cell formation induced by interleukin-1 beta. J. Bone Miner. Res. 11 (1996) 392-400
    • (1996) J. Bone Miner. Res. , vol.11 , pp. 392-400
    • Sato, T.1    Morita, I.2    Sakaguchi, K.3    Nakahama, K.I.4    Smith, W.L.5    Dewitt, D.L.6
  • 25
    • 8244250135 scopus 로고    scopus 로고
    • Transcriptional induction of cyclooxygenase-2 in osteoblasts is involved in interleukin-6-induced osteoclast formation
    • Tai H., Miyaura C., Pilbeam C.C., Tamura T., Ohsugi Y., Koishihara Y., et al. Transcriptional induction of cyclooxygenase-2 in osteoblasts is involved in interleukin-6-induced osteoclast formation. Endocrinology 138 (1997) 2372-2379
    • (1997) Endocrinology , vol.138 , pp. 2372-2379
    • Tai, H.1    Miyaura, C.2    Pilbeam, C.C.3    Tamura, T.4    Ohsugi, Y.5    Koishihara, Y.6
  • 26
    • 0031789431 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and bone mineral density in older women: the Rancho Bernardo study
    • Morton D.J., Barrett-Connor E.L., and Schneider D.L. Nonsteroidal anti-inflammatory drugs and bone mineral density in older women: the Rancho Bernardo study. J. Bone Miner. Res. 13 (1998) 1924-1931
    • (1998) J. Bone Miner. Res. , vol.13 , pp. 1924-1931
    • Morton, D.J.1    Barrett-Connor, E.L.2    Schneider, D.L.3
  • 27
    • 0025066465 scopus 로고
    • Effect of naproxen on cancellous bone in ovariectomized rats
    • Lane N., Coble T., and Kimmel D.B. Effect of naproxen on cancellous bone in ovariectomized rats. J. Bone Miner. Res. 5 (1990) 1029-1035
    • (1990) J. Bone Miner. Res. , vol.5 , pp. 1029-1035
    • Lane, N.1    Coble, T.2    Kimmel, D.B.3
  • 28
    • 0030733305 scopus 로고    scopus 로고
    • Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays
    • Riendeau D., Charleson S., Cromlish W., Mancini J.A., Wong E., and Guay J. Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays. Can. J. Physiol. Pharmacol. 75 (1997) 1088-1095
    • (1997) Can. J. Physiol. Pharmacol. , vol.75 , pp. 1088-1095
    • Riendeau, D.1    Charleson, S.2    Cromlish, W.3    Mancini, J.A.4    Wong, E.5    Guay, J.6
  • 29
    • 0037416464 scopus 로고    scopus 로고
    • d-Tyrosine as a chiral precursor to potent inhibitors of human nonpancreatic secretory phospholipase A2 (IIa) with antiinflammatory activity
    • Hansford K.A., Reid R.C., Clark C.I., Tyndall J.D., Whitehouse M.W., Guthrie T., et al. d-Tyrosine as a chiral precursor to potent inhibitors of human nonpancreatic secretory phospholipase A2 (IIa) with antiinflammatory activity. ChemBioChem 4 (2003) 181-185
    • (2003) ChemBioChem , vol.4 , pp. 181-185
    • Hansford, K.A.1    Reid, R.C.2    Clark, C.I.3    Tyndall, J.D.4    Whitehouse, M.W.5    Guthrie, T.6
  • 30
    • 0141730388 scopus 로고    scopus 로고
    • Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist
    • Arumugam T.V., Arnold N., Proctor L.M., Newman M., Reid R.C., Hansford K.A., et al. Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist. Br. J. Pharmacol. 140 (2003) 71-80
    • (2003) Br. J. Pharmacol. , vol.140 , pp. 71-80
    • Arumugam, T.V.1    Arnold, N.2    Proctor, L.M.3    Newman, M.4    Reid, R.C.5    Hansford, K.A.6
  • 31
    • 33744831263 scopus 로고    scopus 로고
    • R.C. Reid, C.I. Clark, K. Hansford, M.J. Stoermer, R.P. McGeary, K. Schafer, D.P. Fairlie, New amino acid derivatives useful for the treatment of inflammatory disease or condition. WO Patent 200208189, 2001; filed Jul 24, 2001: issued Jan 31, 2002.
  • 32
    • 0023488581 scopus 로고
    • Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee
    • Parfitt A.M., Drezner M.K., Glorieux F.H., Kanis J.A., Malluche H., Meunier P.J., et al. Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J. Bone Miner. Res. 2 (1987) 595-610
    • (1987) J. Bone Miner. Res. , vol.2 , pp. 595-610
    • Parfitt, A.M.1    Drezner, M.K.2    Glorieux, F.H.3    Kanis, J.A.4    Malluche, H.5    Meunier, P.J.6
  • 33
    • 0025210639 scopus 로고
    • Adaptation of cancellous bone to aging and immobilization in the rat: a single photon absorptiometry and histomorphometry study
    • Li X.J., Jee W.S., Chow S.Y., and Woodbury D.M. Adaptation of cancellous bone to aging and immobilization in the rat: a single photon absorptiometry and histomorphometry study. Anat. Rec. 227 (1990) 12-24
    • (1990) Anat. Rec. , vol.227 , pp. 12-24
    • Li, X.J.1    Jee, W.S.2    Chow, S.Y.3    Woodbury, D.M.4
  • 34
    • 0002043349 scopus 로고
    • The physiologic and clinical significance of bone histomorphometric data
    • CRC Press, Boca Raton, Florida U.S.A.
    • Parfitt A.M. The physiologic and clinical significance of bone histomorphometric data. Recker RR Recker RRs. Bone Histomorphometry: Techniques and Interpretation (1983), CRC Press, Boca Raton, Florida U.S.A. 143-224
    • (1983) Recker RR Recker RRs. Bone Histomorphometry: Techniques and Interpretation , pp. 143-224
    • Parfitt, A.M.1
  • 35
    • 0033759918 scopus 로고    scopus 로고
    • Structure, function, and regulation of tartrate-resistant acid phosphatase
    • Oddie G.W., Schenk G., Angel N.Z., Walsh N., Guddat L.W., de Jersey J., et al. Structure, function, and regulation of tartrate-resistant acid phosphatase. Bone 27 (2000) 575-584
    • (2000) Bone , vol.27 , pp. 575-584
    • Oddie, G.W.1    Schenk, G.2    Angel, N.Z.3    Walsh, N.4    Guddat, L.W.5    de Jersey, J.6
  • 36
    • 0032784494 scopus 로고    scopus 로고
    • Discordance between bone turnover and bone loss: effects of aging and ovariectomy in the rat
    • Baldock P.A., Need A.G., Moore R.J., Durbridge T.C., and Morris H.A. Discordance between bone turnover and bone loss: effects of aging and ovariectomy in the rat. J. Bone Miner. Res. 14 (1999) 1442-1448
    • (1999) J. Bone Miner. Res. , vol.14 , pp. 1442-1448
    • Baldock, P.A.1    Need, A.G.2    Moore, R.J.3    Durbridge, T.C.4    Morris, H.A.5
  • 37
    • 12544251402 scopus 로고    scopus 로고
    • Drugs used to treat osteoporosis: the critical need for a uniform nomenclature based on their action on bone remodeling
    • Riggs B.L., and Parfitt A.M. Drugs used to treat osteoporosis: the critical need for a uniform nomenclature based on their action on bone remodeling. J. Bone Miner. Res. 20 (2005) 177-184
    • (2005) J. Bone Miner. Res. , vol.20 , pp. 177-184
    • Riggs, B.L.1    Parfitt, A.M.2
  • 38
    • 0030993372 scopus 로고    scopus 로고
    • Estrogen regulates the rate of bone turnover but bone balance in ovariectomized rats is modulated by prevailing mechanical strain
    • Westerlind K.C., Wronski T.J., Ritman E.L., Luo Z.P., An K.N., Bell N.H., et al. Estrogen regulates the rate of bone turnover but bone balance in ovariectomized rats is modulated by prevailing mechanical strain. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 4199-4204
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 4199-4204
    • Westerlind, K.C.1    Wronski, T.J.2    Ritman, E.L.3    Luo, Z.P.4    An, K.N.5    Bell, N.H.6
  • 40
    • 15044352645 scopus 로고    scopus 로고
    • A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis
    • Woodruff T.M., Arumugam T.V., Shiels I.A., Newman M.L., Ross P.A., Reid R.C., et al. A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis. Int. Immunopharmacol. 5 (2005) 883-892
    • (2005) Int. Immunopharmacol. , vol.5 , pp. 883-892
    • Woodruff, T.M.1    Arumugam, T.V.2    Shiels, I.A.3    Newman, M.L.4    Ross, P.A.5    Reid, R.C.6
  • 41
    • 0034284215 scopus 로고    scopus 로고
    • Type IIA secretory phospholipase A2 up-regulates cyclooxygenase-2 and amplifies cytokine-mediated prostaglandin production in human rheumatoid synoviocytes
    • Bidgood M.J., Jamal O.S., Cunningham A.M., Brooks P.M., and Scott K.F. Type IIA secretory phospholipase A2 up-regulates cyclooxygenase-2 and amplifies cytokine-mediated prostaglandin production in human rheumatoid synoviocytes. J. Immunol. 165 (2000) 2790-2797
    • (2000) J. Immunol. , vol.165 , pp. 2790-2797
    • Bidgood, M.J.1    Jamal, O.S.2    Cunningham, A.M.3    Brooks, P.M.4    Scott, K.F.5
  • 43
    • 0343145699 scopus 로고    scopus 로고
    • Long-term effects of ovariectomy on the mechanical properties and chemical composition of rat bone
    • Peng Z.Q., Vaananen H.K., Zhang H.X., and Tuukkanen J. Long-term effects of ovariectomy on the mechanical properties and chemical composition of rat bone. Bone 20 (1997) 207-212
    • (1997) Bone , vol.20 , pp. 207-212
    • Peng, Z.Q.1    Vaananen, H.K.2    Zhang, H.X.3    Tuukkanen, J.4
  • 44
    • 0021345057 scopus 로고
    • Evidence of sequential remodeling in rat trabecular bone: morphology, dynamic histomorphometry, and changes during skeletal maturation
    • Baron R., Tross R., and Vignery A. Evidence of sequential remodeling in rat trabecular bone: morphology, dynamic histomorphometry, and changes during skeletal maturation. Anat. Rec. 208 (1984) 137-145
    • (1984) Anat. Rec. , vol.208 , pp. 137-145
    • Baron, R.1    Tross, R.2    Vignery, A.3
  • 45
    • 0023803311 scopus 로고
    • Temporal relationship between bone loss and increased bone turnover in ovariectomized rats
    • Wronski T.J., Cintron M., and Dann L.M. Temporal relationship between bone loss and increased bone turnover in ovariectomized rats. Calcif. Tissue Int. 43 (1988) 179-183
    • (1988) Calcif. Tissue Int. , vol.43 , pp. 179-183
    • Wronski, T.J.1    Cintron, M.2    Dann, L.M.3
  • 46
    • 0031689662 scopus 로고    scopus 로고
    • Preadministration of incadronate disodium can prevent bone loss in rat proximal tibial metaphysis when induced by hindlimb immobilization by bandage
    • Li J., Mori S., Mashiba T., Kaji Y., Taki M., Komatsubara S., et al. Preadministration of incadronate disodium can prevent bone loss in rat proximal tibial metaphysis when induced by hindlimb immobilization by bandage. Bone 23 (1998) 459-463
    • (1998) Bone , vol.23 , pp. 459-463
    • Li, J.1    Mori, S.2    Mashiba, T.3    Kaji, Y.4    Taki, M.5    Komatsubara, S.6
  • 47
    • 0026749055 scopus 로고
    • Long-term effect of naproxen on cancellous bone in ovariectomized rats
    • Kimmel D.B., Coble T., and Lane N. Long-term effect of naproxen on cancellous bone in ovariectomized rats. Bone 13 (1992) 167-172
    • (1992) Bone , vol.13 , pp. 167-172
    • Kimmel, D.B.1    Coble, T.2    Lane, N.3
  • 48
    • 0023665454 scopus 로고
    • Trabecular bone architecture in the pathogenesis and prevention of fracture
    • Parfitt A.M. Trabecular bone architecture in the pathogenesis and prevention of fracture. Am. J. Med. 82 (1987) 68-72
    • (1987) Am. J. Med. , vol.82 , pp. 68-72
    • Parfitt, A.M.1
  • 49
    • 0015685641 scopus 로고
    • A structural model for the mechanical behavior of trabecular bone
    • Pugh J.W., Rose R.M., and Radin E.L. A structural model for the mechanical behavior of trabecular bone. J. Biomech. 6 (1973) 657-670
    • (1973) J. Biomech. , vol.6 , pp. 657-670
    • Pugh, J.W.1    Rose, R.M.2    Radin, E.L.3
  • 50
    • 0015667763 scopus 로고
    • Elastic and viscoelastic properties of trabecular bone: dependence on structure
    • Pugh J.W., Rose R.M., and Radin E.L. Elastic and viscoelastic properties of trabecular bone: dependence on structure. J. Biomech. 6 (1973) 475-485
    • (1973) J. Biomech. , vol.6 , pp. 475-485
    • Pugh, J.W.1    Rose, R.M.2    Radin, E.L.3
  • 51
    • 0345305727 scopus 로고    scopus 로고
    • Interrelationships between structural parameters of cancellous bone reveal accelerated structural change at low bone volume
    • Parkinson I.H., and Fazzalari N.L. Interrelationships between structural parameters of cancellous bone reveal accelerated structural change at low bone volume. J. Bone Miner. Res. 18 (2003) 2200-2205
    • (2003) J. Bone Miner. Res. , vol.18 , pp. 2200-2205
    • Parkinson, I.H.1    Fazzalari, N.L.2
  • 52
    • 0022406116 scopus 로고
    • The role of three-dimensional trabecular microstructure in the pathogenesis of vertebral compression fractures
    • Kleerekoper M., Villanueva A.R., Stanciu J., Rao D.S., and Parfitt A.M. The role of three-dimensional trabecular microstructure in the pathogenesis of vertebral compression fractures. Calcif. Tissue Int. 37 (1985) 594-597
    • (1985) Calcif. Tissue Int. , vol.37 , pp. 594-597
    • Kleerekoper, M.1    Villanueva, A.R.2    Stanciu, J.3    Rao, D.S.4    Parfitt, A.M.5
  • 54
    • 0030941730 scopus 로고    scopus 로고
    • Protein kinase C-independent activation of a novel nonspecific phospholipase C pathway by phorbol myristate acetate releases arachidonic acid for prostaglandin synthesis in MC3T3-E1 osteoblasts
    • Rapuano B.E., and Bockman R.S. Protein kinase C-independent activation of a novel nonspecific phospholipase C pathway by phorbol myristate acetate releases arachidonic acid for prostaglandin synthesis in MC3T3-E1 osteoblasts. Prostaglandins 53 (1997) 163-186
    • (1997) Prostaglandins , vol.53 , pp. 163-186
    • Rapuano, B.E.1    Bockman, R.S.2
  • 55
    • 0031027796 scopus 로고    scopus 로고
    • Involvement of phospholipase D activation in endothelin-1-induced release of arachidonic acid in osteoblast-like cells
    • Kozawa O., Suzuki A., Shinoda J., Ozaki N., Oiso Y., and Uematsu T. Involvement of phospholipase D activation in endothelin-1-induced release of arachidonic acid in osteoblast-like cells. J. Cell. Biochem. 64 (1997) 376-381
    • (1997) J. Cell. Biochem. , vol.64 , pp. 376-381
    • Kozawa, O.1    Suzuki, A.2    Shinoda, J.3    Ozaki, N.4    Oiso, Y.5    Uematsu, T.6
  • 57
    • 0033625346 scopus 로고    scopus 로고
    • Augmented prostaglandin E2 generation resulting from increased activities of cytosolic and secretory phospholipase A2 and induction of cyclooxygenase-2 in interleukin-1 beta-stimulated rat calvarial cells during the mineralizing phase
    • Higashi S., Ohishi H., and Kudo I. Augmented prostaglandin E2 generation resulting from increased activities of cytosolic and secretory phospholipase A2 and induction of cyclooxygenase-2 in interleukin-1 beta-stimulated rat calvarial cells during the mineralizing phase. Inflamm. Res. 49 (2000) 102-111
    • (2000) Inflamm. Res. , vol.49 , pp. 102-111
    • Higashi, S.1    Ohishi, H.2    Kudo, I.3
  • 58
    • 0029657888 scopus 로고    scopus 로고
    • Leukotriene B4 stimulates osteoclastic bone resorption both in vitro and in vivo
    • Garcia C., Boyce B.F., Gilles J., Dallas M., Qiao M., Mundy G.R., et al. Leukotriene B4 stimulates osteoclastic bone resorption both in vitro and in vivo. J. Bone Miner. Res. 11 (1996) 1619-1627
    • (1996) J. Bone Miner. Res. , vol.11 , pp. 1619-1627
    • Garcia, C.1    Boyce, B.F.2    Gilles, J.3    Dallas, M.4    Qiao, M.5    Mundy, G.R.6
  • 59
    • 85047692769 scopus 로고    scopus 로고
    • Absence of platelet-activating factor receptor protects mice from osteoporosis following ovariectomy
    • Hikiji H., Ishii S., Shindou H., Takato T., and Shimizu T. Absence of platelet-activating factor receptor protects mice from osteoporosis following ovariectomy. J. Clin. Invest. 114 (2004) 85-93
    • (2004) J. Clin. Invest. , vol.114 , pp. 85-93
    • Hikiji, H.1    Ishii, S.2    Shindou, H.3    Takato, T.4    Shimizu, T.5


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