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Volumn 24, Issue 6, 2006, Pages 547-555

Role of endogenous and exogenous ligands for the peroxisome proliferator-activated receptor α in the development of bleomycin-induced lung injury

Author keywords

Bleomycin; Cytokines; Inflammation; Lung injury; Neutrophil infiltration; Signal transduction

Indexed keywords

BLEOMYCIN; CELL NUCLEUS RECEPTOR; INTERLEUKIN 1BETA; LIGAND; MYELOPEROXIDASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIRINIXIC ACID; POLY(ADENOSINE DIPHOSPHATE RIBOSE); RETINOIC ACID RECEPTOR; STEROID RECEPTOR; THYROID HORMONE RECEPTOR; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA; ANTINEOPLASTIC ANTIBIOTIC; PEROXISOME PROLIFERATOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PYRIMIDINE DERIVATIVE;

EID: 33646799831     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.shk.0000190825.28783.a4     Document Type: Article
Times cited : (35)

References (46)
  • 1
    • 0035099112 scopus 로고    scopus 로고
    • PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis
    • Krishna G, Liu K, Shigemitsu H, Gao M, Raffin TA, Rosen GD: PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis. Am J Pathol 158:997-1004, 2001.
    • (2001) Am J Pathol , vol.158 , pp. 997-1004
    • Krishna, G.1    Liu, K.2    Shigemitsu, H.3    Gao, M.4    Raffin, T.A.5    Rosen, G.D.6
  • 2
    • 0034133548 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Diagnosis and treatment. International consensus statement
    • American Thoracic Society (ATS), and the European Respiratory Society (ERS)
    • American Thoracic Society: Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am J Respir Crit Care Med 161:646-664, 2000.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 646-664
  • 3
    • 0029995678 scopus 로고    scopus 로고
    • Corticosteroids and the treatment of idiopathic pulmonary fibrosis. Past, present, and future
    • Mapel DW, Samet JM, Coultas DB: Corticosteroids and the treatment of idiopathic pulmonary fibrosis. Past, present, and future. Chest 110:1058-1067, 1996.
    • (1996) Chest , vol.110 , pp. 1058-1067
    • Mapel, D.W.1    Samet, J.M.2    Coultas, D.B.3
  • 5
    • 0026389762 scopus 로고
    • Azathioprine combined with prednisone in the treatment of idiopathic pulmonary fibrosis: A prospective double-blind, randomized, placebo-controlled clinical trial
    • Raghu G, Depaso WJ, Cain K, Hammar SP, Wetzel CE, Dreis DF, Hutchinson J, Pardee NE, Winterbauer RH: Azathioprine combined with prednisone in the treatment of idiopathic pulmonary fibrosis: a prospective double-blind, randomized, placebo-controlled clinical trial. Am Rev Respir Dis 144:291-296, 1991.
    • (1991) Am Rev Respir Dis , vol.144 , pp. 291-296
    • Raghu, G.1    Depaso, W.J.2    Cain, K.3    Hammar, S.P.4    Wetzel, C.E.5    Dreis, D.F.6    Hutchinson, J.7    Pardee, N.E.8    Winterbauer, R.H.9
  • 6
    • 0024547095 scopus 로고
    • Randomised controlled trial comparing prednisolone alone with cyclophosphamide and low-dose prednisolone in combination in cryptogenic fibrosing alveolitis
    • Johnson MA, Kwan S, Snell NJ, Nunn AJ, Darbyshire JH, Turner-Warwick M: Randomised controlled trial comparing prednisolone alone with cyclophosphamide and low-dose prednisolone in combination in cryptogenic fibrosing alveolitis. Thorax 44:280-288, 1989.
    • (1989) Thorax , vol.44 , pp. 280-288
    • Johnson, M.A.1    Kwan, S.2    Snell, N.J.3    Nunn, A.J.4    Darbyshire, J.H.5    Turner-Warwick, M.6
  • 8
    • 0023913120 scopus 로고
    • The steroid and thyroid hormone receptor superfamily
    • Evans RM: The steroid and thyroid hormone receptor superfamily. Science 240:889-895, 1988.
    • (1988) Science , vol.240 , pp. 889-895
    • Evans, R.M.1
  • 9
    • 0034406481 scopus 로고    scopus 로고
    • PPAR-γ agonists: Therapeutic role in diabetes, inflammation and cancer
    • Murphy GJ, Holder JC: PPAR-γ agonists: therapeutic role in diabetes, inflammation and cancer. Trends Pharmacol Sci 21:469-474, 2000.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 469-474
    • Murphy, G.J.1    Holder, J.C.2
  • 10
    • 0035955411 scopus 로고    scopus 로고
    • 5-Amino isoquinolinone, a potent inhibitor of poly (adenosine 5′-diphosphate ribose) polymerase, reduces myocardial infarct size
    • Wayman N, McDonald MC, Thompson AS, Threadgill MD, Thiemermann C: 5-Amino isoquinolinone, a potent inhibitor of poly (adenosine 5′-diphosphate ribose) polymerase, reduces myocardial infarct size. Eur J Pharmacol 430:93-100, 2001.
    • (2001) Eur J Pharmacol , vol.430 , pp. 93-100
    • Wayman, N.1    McDonald, M.C.2    Thompson, A.S.3    Threadgill, M.D.4    Thiemermann, C.5
  • 11
    • 0027191040 scopus 로고
    • cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor
    • Sher T, Yi HF, Gonzalez FJ: cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor. Biochemistry 32:5598-5604, 1993.
    • (1993) Biochemistry , vol.32 , pp. 5598-5604
    • Sher, T.1    Yi, H.F.2    Gonzalez, F.J.3
  • 13
    • 7944235591 scopus 로고    scopus 로고
    • WY 14643, a potent exogenous PPAR-α ligand, reduces intestinal injury associated with splanchnic artery occlusion shock
    • Cuzzocrea S, Di Paola R, Mazzon E, Genovese T, Muia C, Caputi AP: WY 14643, a potent exogenous PPAR-α ligand, reduces intestinal injury associated with splanchnic artery occlusion shock. Shock 22:340-346, 2004.
    • (2004) Shock , vol.22 , pp. 340-346
    • Cuzzocrea, S.1    Di Paola, R.2    Mazzon, E.3    Genovese, T.4    Muia, C.5    Caputi, A.P.6
  • 14
    • 10044243883 scopus 로고    scopus 로고
    • Role of endogenous and exogenous ligands for the peroxisome proliferator-activated receptor α (PPAR-α) in the development of inflammatory bowel disease in mice
    • Cuzzocrea S, Di Paola R, Mazzon E, Genovese T, Muia C, Centorrino T, Caputi AP: Role of endogenous and exogenous ligands for the peroxisome proliferator-activated receptor α (PPAR-α) in the development of inflammatory bowel disease in mice. Lab Invest 84:1643-1654, 2004.
    • (2004) Lab Invest , vol.84 , pp. 1643-1654
    • Cuzzocrea, S.1    Di Paola, R.2    Mazzon, E.3    Genovese, T.4    Muia, C.5    Centorrino, T.6    Caputi, A.P.7
  • 15
    • 0031898610 scopus 로고    scopus 로고
    • PPAR-γ: Adipogenic regulator and thiazolidinedione receptor
    • Spiegelman BM: PPAR-γ: adipogenic regulator and thiazolidinedione receptor. Diabetes 47:507-514, 1998.
    • (1998) Diabetes , vol.47 , pp. 507-514
    • Spiegelman, B.M.1
  • 19
    • 0023914820 scopus 로고
    • Simple method of estimating severity of pulmonary fibrosis on a numerical scale
    • Ashcroft T, Simpson JM, Timbrell V: Simple method of estimating severity of pulmonary fibrosis on a numerical scale. J Clin Pathol 41:467-470, 1988.
    • (1988) J Clin Pathol , vol.41 , pp. 467-470
    • Ashcroft, T.1    Simpson, J.M.2    Timbrell, V.3
  • 20
    • 0032585497 scopus 로고    scopus 로고
    • Annexin V binding assay as a tool to measure apoptosis in differentiated neuronal cells
    • Schutte B, Nuydens R, Geerts H, Ramaekers F: Annexin V binding assay as a tool to measure apoptosis in differentiated neuronal cells. J Neurosci Methods 86:63-69, 1998.
    • (1998) J Neurosci Methods , vol.86 , pp. 63-69
    • Schutte, B.1    Nuydens, R.2    Geerts, H.3    Ramaekers, F.4
  • 21
    • 0021998590 scopus 로고
    • Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium
    • Mullane KM, Kraemer R, Smith B: Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. J Pharmacol Methods 14:157-167, 1985.
    • (1985) J Pharmacol Methods , vol.14 , pp. 157-167
    • Mullane, K.M.1    Kraemer, R.2    Smith, B.3
  • 22
    • 0033870127 scopus 로고    scopus 로고
    • Dextran sulfate sodium-induced colonic histopathology, but not altered epithelial ion transport, is reduced by inhibition of phosphodiesterase activity
    • Diaz-Granados N, Howe K, Lu J, McKay DM: Dextran sulfate sodium-induced colonic histopathology, but not altered epithelial ion transport, is reduced by inhibition of phosphodiesterase activity. Am J Pathol 156:2169-2177, 2000.
    • (2000) Am J Pathol , vol.156 , pp. 2169-2177
    • Diaz-Granados, N.1    Howe, K.2    Lu, J.3    McKay, D.M.4
  • 23
    • 0037438377 scopus 로고    scopus 로고
    • Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFκ B-C/EBP-β complex formation
    • Kleemann R, Gervois PP, Verschuren L, Staels B, Princen HM, Kooistra T: Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFκ B-C/EBP-β complex formation. Blood 101:545-551, 2003.
    • (2003) Blood , vol.101 , pp. 545-551
    • Kleemann, R.1    Gervois, P.P.2    Verschuren, L.3    Staels, B.4    Princen, H.M.5    Kooistra, T.6
  • 24
    • 0035823551 scopus 로고    scopus 로고
    • Negative regulation of human fibrinogen gene expression by peroxisome proliferator-activated receptor α agonists via inhibition of CCAAT box/enhancer-binding protein β
    • Gervois P, Vu-Dac N, Kleemann R, Kockx M, Dubois G, Laine B, Kosykh V, Fruchart JC, Kooistra T, Staels B: Negative regulation of human fibrinogen gene expression by peroxisome proliferator-activated receptor α agonists via inhibition of CCAAT box/enhancer-binding protein β. J Biol Chem 276:33471-33477, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 33471-33477
    • Gervois, P.1    Vu-Dac, N.2    Kleemann, R.3    Kockx, M.4    Dubois, G.5    Laine, B.6    Kosykh, V.7    Fruchart, J.C.8    Kooistra, T.9    Staels, B.10
  • 26
    • 0029952585 scopus 로고    scopus 로고
    • Coexpression of TNFα and IL-1β in human acute pulmonary fibrotic diseases: An immunohistochemical analysis
    • Pan LH, Ohtani H, Yamauchi K, Nagura H: Coexpression of TNFα and IL-1β in human acute pulmonary fibrotic diseases: an immunohistochemical analysis. Pathol Int 46:91-99, 1996.
    • (1996) Pathol Int , vol.46 , pp. 91-99
    • Pan, L.H.1    Ohtani, H.2    Yamauchi, K.3    Nagura, H.4
  • 27
    • 0029155678 scopus 로고
    • Potential therapeutic initiatives for fibrogenic lung diseases
    • Goldstein RH, Fine A: Potential therapeutic initiatives for fibrogenic lung diseases. Chest 108:848-855, 1995.
    • (1995) Chest , vol.108 , pp. 848-855
    • Goldstein, R.H.1    Fine, A.2
  • 29
    • 0029152375 scopus 로고
    • Isolation of the human peroxisome proliferator-activated receptor γ cDNA: Expression in hematopoietic cells and chromosomal mapping
    • Greene ME, Blumberg B, McBride OW, Yi HF, Kronquist K, Kwan K, Hsieh L, Greene G, Nimer SD: Isolation of the human peroxisome proliferator-activated receptor γ cDNA: expression in hematopoietic cells and chromosomal mapping. Gene Expr 4:281-299, 1995.
    • (1995) Gene Expr , vol.4 , pp. 281-299
    • Greene, M.E.1    Blumberg, B.2    McBride, O.W.3    Yi, H.F.4    Kronquist, K.5    Kwan, K.6    Hsieh, L.7    Greene, G.8    Nimer, S.D.9
  • 30
    • 7944235591 scopus 로고    scopus 로고
    • WY 14643, a potent exogenous PPAR-α ligand, reduces intestinal injury associated with splanchnic artery occlusion shock
    • Cuzzocrea S, Di Paola R, Mazzon E, Genovese T, Muia C, Caputi AP: WY 14643, a potent exogenous PPAR-α ligand, reduces intestinal injury associated with splanchnic artery occlusion shock. Shock 22:340-346, 2004.
    • (2004) Shock , vol.22 , pp. 340-346
    • Cuzzocrea, S.1    Di Paola, R.2    Mazzon, E.3    Genovese, T.4    Muia, C.5    Caputi, A.P.6
  • 33
    • 0027163384 scopus 로고
    • Cardiac stress protein elevation 24 hours after brief ischaemia or heat stress is associated with resistance to myocardial infarction
    • Marber MS, Latchman DS, Walker JM, Yellon DM: Cardiac stress protein elevation 24 hours after brief ischaemia or heat stress is associated with resistance to myocardial infarction. Circulation 88:1264-1272, 1993.
    • (1993) Circulation , vol.88 , pp. 1264-1272
    • Marber, M.S.1    Latchman, D.S.2    Walker, J.M.3    Yellon, D.M.4
  • 36
    • 0030854951 scopus 로고    scopus 로고
    • Endothelial dysfunction in endotoxic shock: Importance of the activation of poly (ADP ribose) synthetase (PARS) by peroxynitrite
    • Szabo C, Cuzzocrea S, Zingarelli B, O'Connor M, Salzman AL: Endothelial dysfunction in endotoxic shock: importance of the activation of poly (ADP ribose) synthetase (PARS) by peroxynitrite. J Clin Invest 94:723-735, 1997.
    • (1997) J Clin Invest , vol.94 , pp. 723-735
    • Szabo, C.1    Cuzzocrea, S.2    Zingarelli, B.3    O'Connor, M.4    Salzman, A.L.5
  • 37
    • 0031822063 scopus 로고    scopus 로고
    • Peroxynitrite-induced thymocyte apoptosis: The role of caspases and poly (ADP-ribose) synthetase (PARS) activation
    • Virag L, Scott GS, Cuzzocrea S, Marmer D, Salzman AL, Szabo C: Peroxynitrite-induced thymocyte apoptosis: the role of caspases and poly (ADP-ribose) synthetase (PARS) activation. Immunology 94:345-355, 1998.
    • (1998) Immunology , vol.94 , pp. 345-355
    • Virag, L.1    Scott, G.S.2    Cuzzocrea, S.3    Marmer, D.4    Salzman, A.L.5    Szabo, C.6
  • 38
  • 39
    • 0345707635 scopus 로고    scopus 로고
    • Essential roles for angiotensin receptor AT1a in bleomycin-induced apoptosis and lung fibrosis in mice
    • Li X, Rayford H, Uhal BD: Essential roles for angiotensin receptor AT1a in bleomycin-induced apoptosis and lung fibrosis in mice. Am J Pathol 163:2523-2530, 2003.
    • (2003) Am J Pathol , vol.163 , pp. 2523-2530
    • Li, X.1    Rayford, H.2    Uhal, B.D.3
  • 40
    • 0030638505 scopus 로고    scopus 로고
    • Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice
    • Hagimoto N, Kuwano K, Nomoto Y, Kunitake R, Hara N: Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice. Am J Respir Cell Mol Biol 16:91-101, 1997.
    • (1997) Am J Respir Cell Mol Biol , vol.16 , pp. 91-101
    • Hagimoto, N.1    Kuwano, K.2    Nomoto, Y.3    Kunitake, R.4    Hara, N.5
  • 42
    • 0033546190 scopus 로고    scopus 로고
    • Endothelial cell apoptosis induced by the peroxisome proliferator- activated receptor (PPAR) ligand 15-deoxy-δ12, 14-prostaglandin J2
    • Bishop-Bailey D, Hla T: Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-δ12, 14-prostaglandin J2. J Biol Chem 274:17042-17048, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 17042-17048
    • Bishop-Bailey, D.1    Hla, T.2
  • 44
    • 0031819433 scopus 로고    scopus 로고
    • Evidence for the suppression of apoptosis by the peroxisome proliferator-activated receptor α (PPAR α)
    • Roberts RA, James NH, Woodyatt NJ, Macdonald N, Tugwood JD: Evidence for the suppression of apoptosis by the peroxisome proliferator-activated receptor α (PPAR α). Carcinogenesis 19:43-48, 1998.
    • (1998) Carcinogenesis , vol.19 , pp. 43-48
    • Roberts, R.A.1    James, N.H.2    Woodyatt, N.J.3    Macdonald, N.4    Tugwood, J.D.5


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