-
1
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
Friedman JM, Halaas JL: Leptin and the regulation of body weight in mammals. Nature 395:763-770, 1998.
-
(1998)
Nature
, vol.395
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
2
-
-
0141737573
-
Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
-
Ducy P, Amling M, Takeda S, Priemel M, Schilling AF, Beil FT, Shen J, Vinson C, Rueger JM, Karsenty G: Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 100:197-207, 2000.
-
(2000)
Cell
, vol.100
, pp. 197-207
-
-
Ducy, P.1
Amling, M.2
Takeda, S.3
Priemel, M.4
Schilling, A.F.5
Beil, F.T.6
Shen, J.7
Vinson, C.8
Rueger, J.M.9
Karsenty, G.10
-
3
-
-
0030965884
-
Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion
-
Emilsson V, Liu YL, Cawthorne MA, Morton NM, Davenport M: Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. Diabetes 46:313-316, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 313-316
-
-
Emilsson, V.1
Liu, Y.L.2
Cawthorne, M.A.3
Morton, N.M.4
Davenport, M.5
-
4
-
-
0029952911
-
Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells
-
Gainsford T, Willson TA, Metcalf D, Handman E, McFarlane C, Ng A, Nicola NA, Alexander WS, Hilton DJ: Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells. Proc Natl Acad Sci U S A 93:14564-14568, 1996.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 14564-14568
-
-
Gainsford, T.1
Willson, T.A.2
Metcalf, D.3
Handman, E.4
McFarlane, C.5
Ng, A.6
Nicola, N.A.7
Alexander, W.S.8
Hilton, D.J.9
-
5
-
-
0030007116
-
Novel B219/OB receptor isoforms: Possible role of leptin in hematopoiesis and reproduction
-
Cioffi JA, Shafer AW, Zupancic TJ, Smith-Gbur J, Mikhail A, Platika D, Snodgrass HR: Novel B219/OB receptor isoforms: possible role of leptin in hematopoiesis and reproduction. Nat Med 2:585-589, 1996.
-
(1996)
Nat Med
, vol.2
, pp. 585-589
-
-
Cioffi, J.A.1
Shafer, A.W.2
Zupancic, T.J.3
Smith-Gbur, J.4
Mikhail, A.5
Platika, D.6
Snodgrass, H.R.7
-
6
-
-
0032572722
-
Leptin modulates the T-cell immune response and reverses starvation- induced immunosuppression
-
Lord GM, Matarese G, Howard JK, Baker RJ, Bloom SR, Lechler RI: Leptin modulates the T-cell immune response and reverses starvation- induced immunosuppression. Nature 394:897-901, 1998.
-
(1998)
Nature
, vol.394
, pp. 897-901
-
-
Lord, G.M.1
Matarese, G.2
Howard, J.K.3
Baker, R.J.4
Bloom, S.R.5
Lechler, R.I.6
-
7
-
-
0034628016
-
Human leptin enhances activation and proliferation of human circulating T lymphocytes
-
Martin-Romero C, Santos-Alvarez J, Goberna R, Sanchez-Margalet V: Human leptin enhances activation and proliferation of human circulating T lymphocytes. Cell Immunol 199:15-24, 2000.
-
(2000)
Cell Immunol
, vol.199
, pp. 15-24
-
-
Martin-Romero, C.1
Santos-Alvarez, J.2
Goberna, R.3
Sanchez-Margalet, V.4
-
8
-
-
0032508682
-
Biological action of leptin as an angiogenic factor
-
Sierra-Honigmann MR, Nath AK, Murakami C, Garcia-Cardena G, Papapetropoulos A, Sessa WC, Madge LA, Schechner JS, Schwabb MB, Polverini PJ, Flores-Riveros JR: Biological action of leptin as an angiogenic factor. Science 281:1683-1686, 1998.
-
(1998)
Science
, vol.281
, pp. 1683-1686
-
-
Sierra-Honigmann, M.R.1
Nath, A.K.2
Murakami, C.3
Garcia-Cardena, G.4
Papapetropoulos, A.5
Sessa, W.C.6
Madge, L.A.7
Schechner, J.S.8
Schwabb, M.B.9
Polverini, P.J.10
Flores-Riveros, J.R.11
-
9
-
-
0030942844
-
The leptin receptor
-
Tartaglia LA: The leptin receptor. J Biol Chem 272(10):6093-6096, 1997.
-
(1997)
J Biol Chem
, vol.272
, Issue.10
, pp. 6093-6096
-
-
Tartaglia, L.A.1
-
10
-
-
0030250892
-
A role for leptin and its cognate receptor in hematopoiesis
-
Bennett BD, Solar GP, Yuan JQ, Mathias J, Thomas GR, Matthews W: A role for leptin and its cognate receptor in hematopoiesis. Curr Biol 6:1170-1180, 1996.
-
(1996)
Curr Biol
, vol.6
, pp. 1170-1180
-
-
Bennett, B.D.1
Solar, G.P.2
Yuan, J.Q.3
Mathias, J.4
Thomas, G.R.5
Matthews, W.6
-
11
-
-
0033782028
-
Leptin in the regulation of immunity, inflammation, and hematopoiesis
-
Fantuzzi G, Faggioni R: Leptin in the regulation of immunity, inflammation, and hematopoiesis. J Leukoc Biol 68:437-446, 2000.
-
(2000)
J Leukoc Biol
, vol.68
, pp. 437-446
-
-
Fantuzzi, G.1
Faggioni, R.2
-
12
-
-
2442618838
-
The weight of leptin in immunity
-
Cava AL, Matarese G: The weight of leptin in immunity. Nat Rev Immunol 4:371-379, 2004.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 371-379
-
-
Cava, A.L.1
Matarese, G.2
-
13
-
-
17344384196
-
Multiple cytokines and acute inflammation raise mouse leptin levels: Potential role in inflammatory anorexia
-
Sarraf P, Frederich RC, Turner EM, Ma G, Jaskowiak NT, Rivet DJ 3rd, Flier JS, Lowell BB, Fraker DL, Alexander HR: Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia. J Exp Med 185:171-175, 1997.
-
(1997)
J Exp Med
, vol.185
, pp. 171-175
-
-
Sarraf, P.1
Frederich, R.C.2
Turner, E.M.3
Ma, G.4
Jaskowiak, N.T.5
Rivet III, D.J.6
Flier, J.S.7
Lowell, B.B.8
Fraker, D.L.9
Alexander, H.R.10
-
14
-
-
0029863684
-
Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters
-
Grunfeld C, Zhao C, Fuller J, Pollack A, Moser A, Friedman J, Feingold KR: Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters. J Clin Invest 97:2152-2157, 1996.
-
(1996)
J Clin Invest
, vol.97
, pp. 2152-2157
-
-
Grunfeld, C.1
Zhao, C.2
Fuller, J.3
Pollack, A.4
Moser, A.5
Friedman, J.6
Feingold, K.R.7
-
15
-
-
0037338955
-
Endotoxin stimulates leptin in the human and nonhuman primate
-
Landman RE, Puder JJ, Xiao E, Freda PU, Ferin M, Wardlaw SL: Endotoxin stimulates leptin in the human and nonhuman primate. J Clin Endocrinol Metab 88:1285-1291, 2003.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 1285-1291
-
-
Landman, R.E.1
Puder, J.J.2
Xiao, E.3
Freda, P.U.4
Ferin, M.5
Wardlaw, S.L.6
-
16
-
-
0032917633
-
Leptin deficiency enhances sensitivity to endotoxin-induced lethality
-
Faggioni R, Fantuzzi G, Gabay C, Moser A, Dinarello CA, Feingold KR, Grunfeld C: Leptin deficiency enhances sensitivity to endotoxin-induced lethality. Am J Physiol 276(1 Pt 2):R136-R142, 1999.
-
(1999)
Am J Physiol
, vol.276
, Issue.1 PART 2
-
-
Faggioni, R.1
Fantuzzi, G.2
Gabay, C.3
Moser, A.4
Dinarello, C.A.5
Feingold, K.R.6
Grunfeld, C.7
-
17
-
-
0032866142
-
Relationship of plasma leptin to plasma cytokines and human survivalin sepsis and septic shock
-
Arnalich F, Lopez J, Codoceo R, Jim nez M, Madero R, Montiel C: Relationship of plasma leptin to plasma cytokines and human survivalin sepsis and septic shock. J Infect Dis 180:908-911, 1999.
-
(1999)
J Infect Dis
, vol.180
, pp. 908-911
-
-
Arnalich, F.1
Lopez, J.2
Codoceo, R.3
Jim Nez, M.4
Madero, R.5
Montiel, C.6
-
18
-
-
0031769566
-
Plasma leptin levels are increased in survivors of acute sepsis: Associated loss of diurnal rhythm, in cortisol and leptin secretion
-
Bornstein SR, Licinio J, Tauchnitz R, Engelmann L, Negrao AB, Gold P, Chrousos GP: Plasma leptin levels are increased in survivors of acute sepsis: associated loss of diurnal rhythm, in cortisol and leptin secretion. J Clin Endocrinol Metab 83:280-283, 1998.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 280-283
-
-
Bornstein, S.R.1
Licinio, J.2
Tauchnitz, R.3
Engelmann, L.4
Negrao, A.B.5
Gold, P.6
Chrousos, G.P.7
-
19
-
-
17344392147
-
Relation of leptin and tumor necrosis factor alpha to body weight changes in patients with pulmonary tuberculosis
-
Cakir B, Yonem A, Guler S, Odabasi E, Demirbas B, Gursoy G, Aral Y: Relation of leptin and tumor necrosis factor alpha to body weight changes in patients with pulmonary tuberculosis. Horm Res 52:279-283, 1999.
-
(1999)
Horm Res
, vol.52
, pp. 279-283
-
-
Cakir, B.1
Yonem, A.2
Guler, S.3
Odabasi, E.4
Demirbas, B.5
Gursoy, G.6
Aral, Y.7
-
20
-
-
0033304576
-
Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects
-
Ozata M, Ozdemir IC, Licinio J: Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects. J Clin Endocrinol Metab 84:3686-3695, 1999.
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 3686-3695
-
-
Ozata, M.1
Ozdemir, I.C.2
Licinio, J.3
-
21
-
-
0034097825
-
Leptin and the immune system: How nutritional status influences the immune response
-
Matarese G: Leptin and the immune system: how nutritional status influences the immune response. Eur Cytokine Netw 11:7-14, 2000.
-
(2000)
Eur Cytokine Netw
, vol.11
, pp. 7-14
-
-
Matarese, G.1
-
22
-
-
0032741972
-
Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice
-
Howard JK, Lord GM, Matarese G, Vendetti S, Ghatei MA, Ritter MA, Lechler RI, Bloom SR: Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice. J Clin Invest 104:1051-1059, 1999.
-
(1999)
J Clin Invest
, vol.104
, pp. 1051-1059
-
-
Howard, J.K.1
Lord, G.M.2
Matarese, G.3
Vendetti, S.4
Ghatei, M.A.5
Ritter, M.A.6
Lechler, R.I.7
Bloom, S.R.8
-
23
-
-
0037090316
-
Leptin-deficient mice exhibit impaired host defense in Gram-negative pneumonia
-
Mancuso P, Gottschalk A, Phare SM, Peters-Golden M, Lukacs NW, Huffnagle GB: Leptin-deficient mice exhibit impaired host defense in Gram-negative pneumonia. J Immunol 168:4018-4024, 2002.
-
(2002)
J Immunol
, vol.168
, pp. 4018-4024
-
-
Mancuso, P.1
Gottschalk, A.2
Phare, S.M.3
Peters-Golden, M.4
Lukacs, N.W.5
Huffnagle, G.B.6
-
24
-
-
0029643776
-
Community-acquired pneumonia
-
Bartlett JG, Mundy LM: Community-acquired pneumonia. N Engl J Med 333: 1618-1624, 1995.
-
(1995)
N Engl J Med
, vol.333
, pp. 1618-1624
-
-
Bartlett, J.G.1
Mundy, L.M.2
-
25
-
-
0032541830
-
Community-acquired pneumonia
-
Brzown PD, Lerner SA: Community-acquired pneumonia. Lancet 352: 1295-1302, 1998.
-
(1998)
Lancet
, vol.352
, pp. 1295-1302
-
-
Brzown, P.D.1
Lerner, S.A.2
-
26
-
-
1342324587
-
Toll-like receptor 2 plays a role in the early immune reponse to murine pneumococcal pneumonia but does not contribute to antibacterial host defense
-
Knapp S, Wieland CW, van 't Veer C, Takeuchi O, Akira S, Florquin S, van der Poll T: Toll-like receptor 2 plays a role in the early immune reponse to murine pneumococcal pneumonia but does not contribute to antibacterial host defense. J Immunol 172:3132-3138, 2004.
-
(2004)
J Immunol
, vol.172
, pp. 3132-3138
-
-
Knapp, S.1
Wieland, C.W.2
Van 'T Veer, C.3
Takeuchi, O.4
Akira, S.5
Florquin, S.6
Van Der Poll, T.7
-
27
-
-
8344285803
-
LPS-binding protein-deficient mice have an impaired defense against Gram-negative but not Gram-positive pneumonia
-
Branger J, Florquin S, Knapp S, Leemans JC, Pater JM, Speelman P, Golenbock DT, van der Poll T: LPS-binding protein-deficient mice have an impaired defense against Gram-negative but not Gram-positive pneumonia. Int Immunol 16:1605-1611, 2004.
-
(2004)
Int Immunol
, vol.16
, pp. 1605-1611
-
-
Branger, J.1
Florquin, S.2
Knapp, S.3
Leemans, J.C.4
Pater, J.M.5
Speelman, P.6
Golenbock, D.T.7
Van Der Poll, T.8
-
28
-
-
9644289520
-
Platelet-activating factor receptor-deficient mice show an unaltered clearance of nontypeable haemophilus influenzae from their respiratory tract
-
Branger J, Wieland CW, Florquin S, Maris NA, Pater JM, Speelman P, Shimizu T, Ishii S, van der Poll T: Platelet-activating factor receptor-deficient mice show an unaltered clearance of nontypeable haemophilus influenzae from their respiratory tract. Shock 22:543-547, 2004.
-
(2004)
Shock
, vol.22
, pp. 543-547
-
-
Branger, J.1
Wieland, C.W.2
Florquin, S.3
Maris, N.A.4
Pater, J.M.5
Speelman, P.6
Shimizu, T.7
Ishii, S.8
Van Der Poll, T.9
-
29
-
-
10844285293
-
Non-mannose-capped lipoarabinomannan induces lung inflammation via toll-like receptor 2
-
Wieland CW, Knapp S, Florquin S, de Vos AF, Takeda K, Akira S, Golenbock DT, Verbon A, van der Poll T: Non-mannose-capped lipoarabinomannan induces lung inflammation via toll-like receptor 2. Am J Respir Crit Care Med 170: 1367-1374, 2004.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 1367-1374
-
-
Wieland, C.W.1
Knapp, S.2
Florquin, S.3
De Vos, A.F.4
Takeda, K.5
Akira, S.6
Golenbock, D.T.7
Verbon, A.8
Van Der Poll, T.9
-
30
-
-
0033965560
-
Innate immunity and pulmonary host defense
-
Zhang P, Summer WR, Bagby GJ, Nelson S: Innate immunity and pulmonary host defense. Immunol Rev 173:39-51, 2000.
-
(2000)
Immunol Rev
, vol.173
, pp. 39-51
-
-
Zhang, P.1
Summer, W.R.2
Bagby, G.J.3
Nelson, S.4
-
32
-
-
2142726023
-
Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: Increased mortality in the absence of liver injury
-
Moore TA, Lau HY, Cogen AL, Monteleon CL, Standiford TJ: Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury. Shock 20:309-315, 2003.
-
(2003)
Shock
, vol.20
, pp. 309-315
-
-
Moore, T.A.1
Lau, H.Y.2
Cogen, A.L.3
Monteleon, C.L.4
Standiford, T.J.5
-
33
-
-
0036533493
-
Balancing susceptibility to infection and autoimmunity: A role for leptin?
-
Matarese G, La Cava A, Sanna V, Lord GM, Lechler RI, Fontana S, Zappacosta S: Balancing susceptibility to infection and autoimmunity: a role for leptin? Trends Immunol 23:182-187, 2002.
-
(2002)
Trends Immunol
, vol.23
, pp. 182-187
-
-
Matarese, G.1
La Cava, A.2
Sanna, V.3
Lord, G.M.4
Lechler, R.I.5
Fontana, S.6
Zappacosta, S.7
-
34
-
-
0018861450
-
Cell-mediated immunity in genetically obese C57BL/6J ob/ob mice
-
Chandra RK: Cell-mediated immunity in genetically obese C57BL/6J ob/ob) mice. Am J Clin Nutr 33:13-16, 1980.
-
(1980)
Am J Clin Nutr
, vol.33
, pp. 13-16
-
-
Chandra, R.K.1
-
35
-
-
27744512148
-
Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice
-
Wieland CW, Florquin S, Chan ED, Leemans JC, Weijer S, Verbon A, Fantuzzi G, van der Poll T: Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice. Int Immunol 17:1399-1408, 2005.
-
(2005)
Int Immunol
, vol.17
, pp. 1399-1408
-
-
Wieland, C.W.1
Florquin, S.2
Chan, E.D.3
Leemans, J.C.4
Weijer, S.5
Verbon, A.6
Fantuzzi, G.7
Van Der Poll, T.8
-
36
-
-
0037972324
-
Leptin modulates neutrophil phagocytosis of Klebsiella pneumoniae
-
Moore SI, Huffnagle GB, Chen GH, White ES, Mancuso P: Leptin modulates neutrophil phagocytosis of Klebsiella pneumoniae. Infect Immun 71:4182-4185, 2003.
-
(2003)
Infect Immun
, vol.71
, pp. 4182-4185
-
-
Moore, S.I.1
Huffnagle, G.B.2
Chen, G.H.3
White, E.S.4
Mancuso, P.5
-
37
-
-
0029804213
-
The importance of neutrophils in resistance to pneumococcal pneumonia in adult and neonatal mice
-
Garvy BA, Harmsen AG: The importance of neutrophils in resistance to pneumococcal pneumonia in adult and neonatal mice. Inflammation 20:499-512, 1996.
-
(1996)
Inflammation
, vol.20
, pp. 499-512
-
-
Garvy, B.A.1
Harmsen, A.G.2
|