메뉴 건너뛰기




Volumn 147, Issue 6, 2006, Pages 3085-3092

Induction of autoimmune thyroiditis and hypothyroidism by immunization of immunoactive T cell epitope of thyroid peroxidase

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; EPITOPE; RECOMBINANT ENZYME; THYROID PEROXIDASE; THYROXINE;

EID: 33646777755     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2005-1130     Document Type: Article
Times cited : (26)

References (37)
  • 1
    • 0030960547 scopus 로고    scopus 로고
    • The epidemiology of thyroid disease and implication for screening
    • Wang C, Crapo LM 1997 The epidemiology of thyroid disease and implication for screening. Endocrinol Metab Clin North Am 26:189-218
    • (1997) Endocrinol Metab Clin North Am , vol.26 , pp. 189-218
    • Wang, C.1    Crapo, L.M.2
  • 2
    • 0001669919 scopus 로고
    • Zur Kenntnis der lymphomaosen veranderung der schild-druse (strume lymphomatosa)
    • Hashimoto H 1912 Zur Kenntnis der lymphomaosen veranderung der schild-druse (strume lymphomatosa). Arch Klin Chir 97:219-248
    • (1912) Arch Klin Chir , vol.97 , pp. 219-248
    • Hashimoto, H.1
  • 3
    • 0022182334 scopus 로고
    • Purification of the human thyroid peroxidase and its identification as the microsomal antigen involved in autoimmune thyroid diseases
    • Czarnocka B, Ruf J, Ferrand M, Carayon P, Lissitzky S 1985 Purification of the human thyroid peroxidase and its identification as the microsomal antigen involved in autoimmune thyroid diseases. FEBS Lett 190:147-152
    • (1985) FEBS Lett , vol.190 , pp. 147-152
    • Czarnocka, B.1    Ruf, J.2    Ferrand, M.3    Carayon, P.4    Lissitzky, S.5
  • 4
    • 0023576002 scopus 로고
    • Isolation of a complementary DNA clone for thyroid microsomal antigen. Homology with the gene for thyroid peroxidase
    • Seto P, Hirayu H, Magnusson RP, Gestautas J, Portmann L, DeGroot LJ, Rapoport B 1987 Isolation of a complementary DNA clone for thyroid microsomal antigen. Homology with the gene for thyroid peroxidase. J Clin Invest 80:1205-1208
    • (1987) J Clin Invest , vol.80 , pp. 1205-1208
    • Seto, P.1    Hirayu, H.2    Magnusson, R.P.3    Gestautas, J.4    Portmann, L.5    DeGroot, L.J.6    Rapoport, B.7
  • 5
    • 0023661371 scopus 로고
    • Thyroperoxidase, an auto-antigen with a mosaic structure made of nuclear and mitochondrial gene modules
    • Libert F, Ruel J, Lufgate M, Swillens S, Alexander N, Vassart G, Dinsart C 1987 Thyroperoxidase, an auto-antigen with a mosaic structure made of nuclear and mitochondrial gene modules. EMBO J 6:4193-4196
    • (1987) EMBO J , vol.6 , pp. 4193-4196
    • Libert, F.1    Ruel, J.2    Lufgate, M.3    Swillens, S.4    Alexander, N.5    Vassart, G.6    Dinsart, C.7
  • 6
    • 0002360558 scopus 로고
    • Thyroid peroxidase as an autoantigen in autoimmune thyroid disease: Update
    • Rapoport B, McLachlan S 1994 Thyroid peroxidase as an autoantigen in autoimmune thyroid disease: update. Endocr Rev 3:96-102
    • (1994) Endocr Rev , vol.3 , pp. 96-102
    • Rapoport, B.1    McLachlan, S.2
  • 7
    • 0031793728 scopus 로고    scopus 로고
    • Thyroid peroxidase: Developments in our understanding of its structure and the relevance of these findings to autoimmunity
    • Banga JP 1998 Thyroid peroxidase: developments in our understanding of its structure and the relevance of these findings to autoimmunity. Curr Opin Endocrinol Diabetes 5:275-281
    • (1998) Curr Opin Endocrinol Diabetes , vol.5 , pp. 275-281
    • Banga, J.P.1
  • 8
    • 0029896946 scopus 로고    scopus 로고
    • Chronic autoimmune thyroiditis
    • Dayan CM, Daniels GH 1996 Chronic autoimmune thyroiditis. N Engl J Med 335:99-107
    • (1996) N Engl J Med , vol.335 , pp. 99-107
    • Dayan, C.M.1    Daniels, G.H.2
  • 9
    • 7944239762 scopus 로고
    • Cytotoxic effects of Hashimoto serum and thyroid cells in tissue culture
    • Pulvertaft RJV, Doniach D, Roitt IM, Hudson RV 1959 Cytotoxic effects of Hashimoto serum and thyroid cells in tissue culture. Lancet 2:214-216
    • (1959) Lancet , vol.2 , pp. 214-216
    • Pulvertaft, R.J.V.1    Doniach, D.2    Roitt, I.M.3    Hudson, R.V.4
  • 10
    • 0022645294 scopus 로고
    • Association between thyroid microsomal antibodies of subclass IgG-1 and hypothyroidism in autoimmune postpartum thyroiditis
    • Jansson R, Thompson PM, Clark F, McLachlan SM 1986 Association between thyroid microsomal antibodies of subclass IgG-1 and hypothyroidism in autoimmune postpartum thyroiditis. Clin Exp Immunol 63:80-86
    • (1986) Clin Exp Immunol , vol.63 , pp. 80-86
    • Jansson, R.1    Thompson, P.M.2    Clark, F.3    McLachlan, S.M.4
  • 11
    • 0021211312 scopus 로고
    • Antibody-dependent cell-mediated cytotoxicity against human thyroid cells in Hashimoto's thyroiditis but not Graves' disease
    • Bogner U, Schleusener H, Wall JR 1984 Antibody-dependent cell-mediated cytotoxicity against human thyroid cells in Hashimoto's thyroiditis but not Graves' disease. J Clin Endocrinol Metab 59:734-738
    • (1984) J Clin Endocrinol Metab , vol.59 , pp. 734-738
    • Bogner, U.1    Schleusener, H.2    Wall, J.R.3
  • 12
    • 0023083181 scopus 로고
    • The thyroid microenvironment in autoimmune thyroid disease: Effects of TSH and lymphokines on thyroid lymphocytes and thyroid cells
    • Copenh
    • McLachlan SM, Pegg CAS, Atherton MC, Middleton SL, Dickinson A, Clark F, Rees Smith B 1987 The thyroid microenvironment in autoimmune thyroid disease: effects of TSH and lymphokines on thyroid lymphocytes and thyroid cells. Acta Endocrinol (Copenh) 281:125-132
    • (1987) Acta Endocrinol , vol.281 , pp. 125-132
    • McLachlan, S.M.1    Pegg, C.A.S.2    Atherton, M.C.3    Middleton, S.L.4    Dickinson, A.5    Clark, F.6    Rees Smith, B.7
  • 13
    • 0029943281 scopus 로고    scopus 로고
    • Antibody-dependent cell-mediated cytotoxicity in autoimmune thyroid disease: Relationship to antithyroid antibodies
    • Rodien P, Madec. A-M, Ruf J, Rajas F, Bornet H, Carayon P, Orgiazzi J 1996 Antibody-dependent cell-mediated cytotoxicity in autoimmune thyroid disease: relationship to antithyroid antibodies. J Clin Endocrinol Metab 81:2595-2600
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2595-2600
    • Rodien, P.1    Madec, A.-M.2    Ruf, J.3    Rajas, F.4    Bornet, H.5    Carayon, P.6    Orgiazzi, J.7
  • 14
    • 0031029105 scopus 로고    scopus 로고
    • Recombinant thyroid peroxidase-specific Fab converted to immunoglobulin (IgG) molecules: Evidence for thyroid cell damage by IgG1 but not IgG4 autoantibodies
    • Guo J, Jaume JC, Rapoport B, McLachlan SM 1997 Recombinant thyroid peroxidase-specific Fab converted to immunoglobulin (IgG) molecules: evidence for thyroid cell damage by IgG1 but not IgG4 autoantibodies. J Clin Endocrinol Metab 82:925-931
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 925-931
    • Guo, J.1    Jaume, J.C.2    Rapoport, B.3    McLachlan, S.M.4
  • 15
    • 0030576932 scopus 로고    scopus 로고
    • Autoantibody-mediated capture and presentation of autoantigen to T cells via the Fc epsilon receptor by a recombinant human autoantibody Fab converted to IgE
    • Guo J, Quaratino S, Jaume JC, Costante G, Londei M, McLachlan SM, Rapoport B 1996 Autoantibody-mediated capture and presentation of autoantigen to T cells via the Fc epsilon receptor by a recombinant human autoantibody Fab converted to IgE. J Immunol Methods 195:81-92
    • (1996) J Immunol Methods , vol.195 , pp. 81-92
    • Guo, J.1    Quaratino, S.2    Jaume, J.C.3    Costante, G.4    Londei, M.5    McLachlan, S.M.6    Rapoport, B.7
  • 16
    • 10844266513 scopus 로고    scopus 로고
    • Human autoantibodies modulate the T cell epitope repertoire but fail to unmask a pathogenic cryptic epitope
    • Quaratino S, Osman M, Ruf J, McLachlan SM, Rapoport B, Londei M 2005 Human autoantibodies modulate the T cell epitope repertoire but fail to unmask a pathogenic cryptic epitope. J Immunol 174:557-563
    • (2005) J Immunol , vol.174 , pp. 557-563
    • Quaratino, S.1    Osman, M.2    Ruf, J.3    McLachlan, S.M.4    Rapoport, B.5    Londei, M.6
  • 17
    • 0037646537 scopus 로고    scopus 로고
    • Localization of the discontinuous immunodominant region recognized by human anti-thyroperoxidase autoantibodies in autoimmune thyroid diseases
    • Bresson D, Cerutti M, Devauchelle G, Pugniere M, Roquet F, Bes C, Bossard C, Chardes T, Peraldi-Roux S 2003 Localization of the discontinuous immunodominant region recognized by human anti-thyroperoxidase autoantibodies in autoimmune thyroid diseases. J Biol Chem 278:9560-9569
    • (2003) J Biol Chem , vol.278 , pp. 9560-9569
    • Bresson, D.1    Cerutti, M.2    Devauchelle, G.3    Pugniere, M.4    Roquet, F.5    Bes, C.6    Bossard, C.7    Chardes, T.8    Peraldi-Roux, S.9
  • 18
    • 0024430122 scopus 로고
    • Relationship between immunological structure and biochemical properties of human thyroid peroxidase
    • Ruf J, Toubert M, Czarnocka B, Durand-Gorde J, Ferrand M, Carayon P 1989 Relationship between immunological structure and biochemical properties of human thyroid peroxidase. Endocrinology 125:1211-1218
    • (1989) Endocrinology , vol.125 , pp. 1211-1218
    • Ruf, J.1    Toubert, M.2    Czarnocka, B.3    Durand-Gorde, J.4    Ferrand, M.5    Carayon, P.6
  • 19
    • 0027169311 scopus 로고
    • Human organ-specific autoimmune disease: Molecular cloning and expression of an autoantibody gene repertoire for a major autoantigen reveals an antigenic dominant region and restricted immunoglobulin gene usage in the target organ
    • Chazenbalk GD, Portolano S, Russo D, Hutchison JS, Rapoport B, McLachlan SM 1993 Human organ-specific autoimmune disease: molecular cloning and expression of an autoantibody gene repertoire for a major autoantigen reveals an antigenic dominant region and restricted immunoglobulin gene usage in the target organ. J Clin Invest 92:62-74
    • (1993) J Clin Invest , vol.92 , pp. 62-74
    • Chazenbalk, G.D.1    Portolano, S.2    Russo, D.3    Hutchison, J.S.4    Rapoport, B.5    McLachlan, S.M.6
  • 20
    • 18844414550 scopus 로고    scopus 로고
    • New insights into the conformational dominant epitopes on thyroid peroxidase recognized by human autoantibodies
    • Bresson D, Rebuffat SA, Nguyen B, Banga JP, Gardas A, Peraldi-Roux S 2005 New insights into the conformational dominant epitopes on thyroid peroxidase recognized by human autoantibodies. Endocrinology 146:2834-2844
    • (2005) Endocrinology , vol.146 , pp. 2834-2844
    • Bresson, D.1    Rebuffat, S.A.2    Nguyen, B.3    Banga, J.P.4    Gardas, A.5    Peraldi-Roux, S.6
  • 22
    • 0020586664 scopus 로고
    • Thyroid autoantibody synthesis by cultures of thyroid and peripheral blood lymphocytes: I. Lymphocyte makers and response to pokeweed mitogen
    • McLachlan SM, Dickinson AM, Malcolm A, Farndon JR, Young E, Proctor SJ, Smith BR 1983 Thyroid autoantibody synthesis by cultures of thyroid and peripheral blood lymphocytes: I. Lymphocyte makers and response to pokeweed mitogen. Clin Exp Immunol 52:45-53
    • (1983) Clin Exp Immunol , vol.52 , pp. 45-53
    • McLachlan, S.M.1    Dickinson, A.M.2    Malcolm, A.3    Farndon, J.R.4    Young, E.5    Proctor, S.J.6    Smith, B.R.7
  • 23
    • 0036514975 scopus 로고    scopus 로고
    • Autoimmune thyroid disease: New models of cell death in autoimmunity
    • Stassi G, De Maria R 2002 Autoimmune thyroid disease: new models of cell death in autoimmunity. Nat Rev Immunol 2:195-204
    • (2002) Nat Rev Immunol , vol.2 , pp. 195-204
    • Stassi, G.1    De Maria, R.2
  • 25
    • 0034513553 scopus 로고    scopus 로고
    • Autoimmune response to the thyroid in humans: Thyroid peroxidase: the common autoantigenic denominator
    • McLachlan SM, Rapoport B 2000 Autoimmune response to the thyroid in humans: thyroid peroxidase: the common autoantigenic denominator. Int Rev Immunol 19:587-618
    • (2000) Int Rev Immunol , vol.19 , pp. 587-618
    • McLachlan, S.M.1    Rapoport, B.2
  • 27
    • 0026049253 scopus 로고
    • T cell responses to synthetic thyroid peroxidase peptides in autoimmune thyroid disease
    • Tandon N, Freeman M, Weetman AP 1991 T cell responses to synthetic thyroid peroxidase peptides in autoimmune thyroid disease. Clin Exp Immunol 86:56-60
    • (1991) Clin Exp Immunol , vol.86 , pp. 56-60
    • Tandon, N.1    Freeman, M.2    Weetman, A.P.3
  • 28
    • 0026697394 scopus 로고
    • Proliferative responses of peripheral blood mononuclear cells from patients with autoimmune thyroid diseases to synthetic peptide epitopes of human thyroid peroxidase
    • Kawakami Y, Fisfalen ME, DeGroot LJ 1992 Proliferative responses of peripheral blood mononuclear cells from patients with autoimmune thyroid diseases to synthetic peptide epitopes of human thyroid peroxidase. Autoimmunity 13:17-26
    • (1992) Autoimmunity , vol.13 , pp. 17-26
    • Kawakami, Y.1    Fisfalen, M.E.2    DeGroot, L.J.3
  • 29
    • 0023891685 scopus 로고    scopus 로고
    • Microsomal antigen-reactive lymphocyte lines and clones derived from thyroid tissue of patients with Graves' disease
    • Fisfalen ME, DeGroot LJ, Quintans J, Franklin WA, Soltani K 1998 Microsomal antigen-reactive lymphocyte lines and clones derived from thyroid tissue of patients with Graves' disease. J Clin Endocrinol Metab 66:776-784
    • (1998) J Clin Endocrinol Metab , vol.66 , pp. 776-784
    • Fisfalen, M.E.1    DeGroot, L.J.2    Quintans, J.3    Franklin, W.A.4    Soltani, K.5
  • 31
    • 0842291558 scopus 로고    scopus 로고
    • Development of a murine model of autoimmune thyroiditis induced with homologous mouse thyroid peroxidase
    • Ng HP, Banga JP, Kung AW 2004 Development of a murine model of autoimmune thyroiditis induced with homologous mouse thyroid peroxidase. Endocrinology 145:809-816
    • (2004) Endocrinology , vol.145 , pp. 809-816
    • Ng, H.P.1    Banga, J.P.2    Kung, A.W.3
  • 32
    • 0026536671 scopus 로고
    • Mapping epitope specificities of monoclonal antibodies to thyroid peroxidase using recombinant antigen preparations
    • Ewins DL, Barnett PS, Tomlinson RW, McGregor AM, Banga JP 1992 Mapping epitope specificities of monoclonal antibodies to thyroid peroxidase using recombinant antigen preparations. Autoimmunity 11:1141-1149
    • (1992) Autoimmunity , vol.11 , pp. 1141-1149
    • Ewins, D.L.1    Barnett, P.S.2    Tomlinson, R.W.3    McGregor, A.M.4    Banga, J.P.5
  • 33
    • 0036840428 scopus 로고    scopus 로고
    • Delineation of five thyroglobulin T cell epitopes with pathogenic potential in experimental autoimmune thyroiditis
    • Panayotis V, Marianne MS, Carayanniotis G 2002 Delineation of five thyroglobulin T cell epitopes with pathogenic potential in experimental autoimmune thyroiditis. J Immunol 169:5332-5337
    • (2002) J Immunol , vol.169 , pp. 5332-5337
    • Panayotis, V.1    Marianne, M.S.2    Carayanniotis, G.3
  • 35
    • 1842454981 scopus 로고    scopus 로고
    • Evaluation of conformational epitopes on thyroid peroxidase by antipeptide antibody binding and mutagenesis
    • Gora M, Gardas A, Wiktorowicz W, Hobby P, Watson PF, Weetman AP 2004 Evaluation of conformational epitopes on thyroid peroxidase by antipeptide antibody binding and mutagenesis. Clin Exp Immunol 136:137-144
    • (2004) Clin Exp Immunol , vol.136 , pp. 137-144
    • Gora, M.1    Gardas, A.2    Wiktorowicz, W.3    Hobby, P.4    Watson, P.F.5    Weetman, A.P.6
  • 36
    • 18944363944 scopus 로고    scopus 로고
    • Tolerogenic semimature dendritic cells suppress experimental autoimmune thyroiditis by activation of thyroglobulin-specific CD4+CD25+ T cells
    • Verginis P, Li HS, Carayanniotis G 2005 Tolerogenic semimature dendritic cells suppress experimental autoimmune thyroiditis by activation of thyroglobulin-specific CD4+CD25+ T cells. J Immunol 174:7433-7439
    • (2005) J Immunol , vol.174 , pp. 7433-7439
    • Verginis, P.1    Li, H.S.2    Carayanniotis, G.3
  • 37
    • 17044364732 scopus 로고    scopus 로고
    • High incidence of spontaneous autoimmune thyroiditis in immunocompetent self-reactive human T cell receptor transgenic mice
    • Badami E, Maiuri L, Quaratino S 2005 High incidence of spontaneous autoimmune thyroiditis in immunocompetent self-reactive human T cell receptor transgenic mice. J Autoimmunity 24:85-91
    • (2005) J Autoimmunity , vol.24 , pp. 85-91
    • Badami, E.1    Maiuri, L.2    Quaratino, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.