The expression of xenobiotic-metabolizing enzymes in human prostate and in prostate epithelial cells (PECs) derived from primary cultures

Prostate

Volumn 66, Issue 8, 2006, Pages 876-885

  Al Buheissi, S Z ^a,b   Cole, K J ^a   Hewer, A ^a   Kumar, V ^a   Bryan, R L ^b   Hudson, D L ^a   Patel, H R ^b,c   Nathan, S ^b   Miller, R A ^b   Phillips, D H ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b WHITTINGTON HOSPITAL   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cytochrome P450; N acetyltransferase; Primary cultures; Prostate cancer; Prostate epithelial cells

Indexed keywords

2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; ACYLTRANSFERASE; CARCINOGEN; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; HETEROCYCLIC AMINE; PHOSPHORUS 32;

ARTICLE; AUTORADIOGRAPHY; CARCINOGENICITY; CELL VIABILITY; CONTROLLED STUDY; CYTOPLASM; DIET; DNA ADDUCT; DNA DAMAGE; DNA ISOLATION; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; METABOLIC ACTIVATION; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE EPITHELIUM; PROTEIN EXPRESSION; WESTERN BLOTTING; XENOBIOTIC METABOLISM;

ARYLAMINE N-ACETYLTRANSFERASE; BIOTRANSFORMATION; BLOTTING, WESTERN; CARCINOGENS; CELLS, CULTURED; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; DNA ADDUCTS; DNA, NEOPLASM; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; IMIDAZOLES; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MALE; PROSTATE; QUINOLINES; XENOBIOTICS;

EID: 33646749758     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.20400     Document Type: Article

References (51)

1. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005;55(2):74-108.
2. Cook LS, Goldoft M, Schwartz SM, Weiss NS. Incidence of adenocarcinoma of the prostate in Asian immigrants to the United States and their descendants. J Urol 1999;161(1):152-155.
3. Shibata A, Whittemore AS, Imai K, Kolonel LN, Wu AH, John EM, Stamey TA, Paffenbarger RS. Serum levels of prostate-specific antigen among Japanese-American and native Japanese men. J Natl Cancer Inst 1997;89(22):1716-1720.
4. Zheng W, Gustafson DR, Sinha R, Cerhan JR, Moore D, Hong CP, Anderson KE, Kushi LH, Sellers TA, Folsom AR. Well-done meat intake and the risk of breast cancer. J Natl Cancer Inst 1998;90(22):1724-1729.
5. Sinha R, Gustafson DR, Kulldorff M, Wen WQ, Cerhan JR, Zheng W. 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, a carcinogen in high-temperature-cooked meat, and breast cancer risk. J Natl Cancer Inst 2000;92(16):1352-1354.
6. Felton JS, Knize MG. New mutagens from cooked food. [Review] [49 refs]. Prog Clin Biol Res 1990;347:19-38.
7. Sinha R, Rothman N, Brown ED, Salmon CP, Knize MG, Swanson CA, Rossi SC, Mark SD, Levander OA, Felton JS. High concentrations of the carcinogen 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP) occur in chicken but are dependent on the cooking method. Cancer Res 1995;55(20):4516-4519.
8. Gross GA, Gruter A. Quantitation of mutagenic/carcinogenic heterocyclic aromatic amines in food products. J Chromatogr 1992;592(1-2):271-278.
9. Felton JS, Knize MG, Shen NH, Lewis PR, Andresen BD, Happe J, Hatch FT. The isolation and identification of a new mutagen from fried ground beef: 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Carcinogenesis 1986;7(7):1081-1086.
10. Ito N, Hasegawa R, Sano M, Tamano S, Esumi H, Takayama S, Sugimura T. A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine (PhIP). Carcinogenesis 1991;12(8):1503-1506.
11. Shirai T, Sano M, Tamano S, Takahashi S, Hirose M, Futakuchi M, Hasegawa R, Imaida K, Matsumoto K, Wakabayashi K, Sugimura T, Ito N. The prostate: A target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) derived from cooked foods. Cancer Res 1997;57(2):195-198.
12. Augustsson K, Skog K, Jagerstad M, Steineck G. Assessment of the human exposure to heterocyclic amines. Carcinogenesis 1997;18(10):1931-1935.
13. McManus ME, Burgess WM, Veronese ME, Huggett A, Quattrochi LC, Tukey RH. Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450. Cancer Res 1990;50(11):3367-3376.
14. Lin DX, Lang NP, Kadlubar FF. Species differences in the biotransformation of the food-borne carcinogen 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine by hepatic microsomes and cytosols from humans, rats, and mice. Drug Metab Dispos 1995;23(4):518-524.
15. Lin D, Meyer DJ, Ketterer B, Lang NP, Kadlubar FF. Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: A possible mechanism of organ specificity in their cardnogenesis. Cancer Res 1994;54(18):4920-4926.
16. Nowell SA, Massengill JS, Williams S, Radominska Pandya A, Tephly TR, Cheng Z, Strassburg CP, Tukey RH, MacLeod SL, Lang NP, Kadlubar FF. Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human microsomal UDP-glucuronosyltransferases: Identification of specific UGT1A family isoforms involved. Carcinogenesis 1999;20(6):1107-1114.
17. Finnstrom N, Bjelfman C, Soderstrom TG, Smith G, Egevad L, Norlen BJ, Wolf CR, Rane A. Detection of cytochrome P450 mRNA transcripts in prostate samples by RT-PCR. Eur J Clin Invest 2001;31(10):880-886.
18. Nishimura M, Yaguti H, Yoshitsugu H, Naito S, Satoh T. Tissue distribution of mRNA expression of human cytochrome P450 isoforms assessed by high-sensitivity real-time reverse transcription PCR. Yakugaku Zasshi 2003;123(5):369-375.
19. Williams JA, Martin FL, Muir GH, Hewer A, Grover PL, Phillips DH. Metabolic activation of carcinogens and expression of various cytochromes P450 in human prostate tissue. Carcinogenesis 2000;21(9):1683-1689.
20. Wang CY, Debiec-Rychter M, Schut HA, Morse P, Jones RF, Archer C, et al. N-Acetyltransferase expression and DNA binding of N-hydroxyheterocyclic amines in human prostate epithelium. Carcinogenesis 1999;20(8):1591-1595.
21. Hein DW. Acetylator genotype and arylamine-induced carcinogenesis. Biochim Biophys Acta 1988;948(1):37-66.
22. Fry PM, Hudson DL, O'Hare MJ, Masters JR. Comparison of marker protein expression in benign prostatic hyperplasia in vivo and in vitro. BJU Int 2000;85(4):504-513.
23. Adams DJ, Seilman S, Amelizad Z, Oesch F, Wolf CR. Identification of human cytochromes P-450 analogous to forms induced by phenobarbital and 3-methylcholanthrene in the rat. Biochem J 1985;232(3):869-876.
24. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-254.
25. Gupta RC, Reddy MV, Randerath K. 32P-postlabeling analysis of non-radioactive aromatic carcinogen-DNA adducts. Carcinogenesis 1982;3(9):1081-1092.
26. Hall M, She MN, Wild D, Fasshauer I, Hewer A, Phillips DH. Tissue distribution of DNA adducts in CDF1 mice fed 2-amino-3-methylimidazo[4,5-f] quinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ). Carcinogenesis 1990;11(6):1005-1011.
27. Hudson DL, O'Hare M, Watt FM, Masters JR. Proliferative heterogeneity in the human prostate: Evidence for epithelial stem cells. Lab Invest 2000;80(8):1243-1250.
28. McNeal JE. Origin and evolution of benign prostatic enlargement. Invest Urol 1978;15(4):340-345.
29. Ragavan N, Hewitt R, Cooper LJ, Ashton KM, Hindley AC, Nicholson CM, Fullwood NJ, Matanhelia SS, Martin FL. CYP1B1 expression in prostate is higher in the peripheral than in the transition zone. Cancer Lett 2004;215(1):69-78.
30. Gonzalez FJ, Gelboin HV. Human cytochromes P450: Evolution and cDNA-directed expression. Environ Health Perspect 1992;98:81-85.
31. Wolf CR, Smith CA, Forman D. Metabolic polymorphisms in carcinogen metabolising enzymes and cancer susceptibility. Br Med Bull 1994;50(3):718-731.
32. Guengerich FP. Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy. Cancer Res 1988;48(11):2946-2954.
33. Kawajiri K, Fujii-Kuriyama Y. P450 and human cancer. Jpn J Cancer Res 1991;82(12):1325-1335.
34. Pacifici GM, Bencini C, Rane A. Acetyltransferase in humans: Development and tissue distribution. Pharmacology 1986;32(5):283-291.
35. Grant DM, Lottspeich F, Meyer UA. Evidence for two closely related isozymes of arylamine N-acetyltransferase in human liver. FEBS Lett 1989;244(1):203-207.
36. Coroneos E, Sim E. N-acetyltransferase in human urothelium and bladder cell lines. Biochem Soc Trans 1991;19(2):129S.
37. Kloth MT, Gee RL, Messing EM, Swaminathan S. Expression of N-acetyltransferase (NAT) in cultured human uroepithelial cells. Carcinogenesis 1994;15(12):2781-2787.
38. Hickman D, Pope J, Patil SD, Fakis G, Smelt V, Stanley LA, Payton M, Unadkat JD, Sim E. Expression of arylamine N-acetyltransferase in human intestine. Gut 1998;42(3):402-409.
39. Stanley LA, Coroneos E, Cuff R, Hickman D, Ward A, Sim E. Immunochemical detection of arylamine N-acetyltransferase in normal and neoplastic bladder. J Histochem Cytochem 1996;44(9):1059-1067.
40. Williams JA, Stone EM, Fakis G, Johnson N, Cordell JA, Meinl W, Glatt H, Sim E, Phillips DH. N-Acetyltransferases, sulfotransferases and heterocyclic amine activation in the breast. Pharmacogenetics 2001;11(5):373-388.
41. Peehl DM. Culture of human prostatic epithelial cells. In: Fretland AJ, editor. Culture of epithelial cells. New York: Wiley-Liss; 1992. pp 159-180.
42. Kassen A, Sutkowski DM, Ahn H, Sensibar JA, Kozlowski JM, Lee C. Stromal cells of the human prostate: Initial isolation and characterization. Prostate 1996;28(2):89-97.
43. Lechner JF. Replicative cultures of human prostatic epithelial cells. [Review] [58 refs]. Prog Clin Biol Res 1987;239:497-509.
44. McKeehan WL, Adams PS, Rosser MP. Direct mitogenic effects of insulin, epidermal growth factor, glucocorticoid, cholera toxin, unknown pituitary factors and possibly prolactin, but not androgen, on normal rat prostate epithelial cells in serum-free, primary cell culture. Cancer Res 1984;44(5):1998-2010.
45. Peehl DM, Stamey TA. Serum-free growth of adult human prostatic epithelial cells. In Vitro 1986;22(2):82-90.
46. McKeehan WL, Adams PS, Rosser MP. Modified nutrient medium MCDB 151, defined growth factors, cholera toxin, pituitary factors, and horse sérum support epithelial cell and suppress fibroblast proliferation in primary cultures of rat ventral prostate cells. In Vitro 1982;18(2):87-91.
47. Sharma P, Schreiber-Agus N. Mouse models of prostate cancer. Oncogene 1999;18(38):5349-5355.
48. Sterling KM Jr, Cutroneo KR. Constitutive and inducible expression of cytochromes P4501A (CYP1A1 and CYP1A2) in normal prostate and prostate cancer cells. J Cell Biochem 2004;91(2):423-429.
49. Martin FL, Cole KJ, Muir GH, Kooiman GG, Williams JA, Sherwood RA, Grover PL, Phillips DH. Primary cultures of prostate cells and their ability to activate carcinogens. Prostate Cancer Prostatic Dis 2002;5(2):96-104.
50. Phillips DH, Martin FL, Williams JA, Wheat LM, Nolan L, Cole KJ, Grover PL. Mutagens in human breast lipid and milk: The search for environmental agents that initiate breast cancer. Environ Mol Mutagen 2002;39(2-3):143-149.
51. Peehl DM, Sellers RG. Epithelial cell culture: Prostate. In: Atala A, Lanza R, editors. Methods of tissue engineering. San Diego, CA: Academic Press; 2002. pp 247-261.