Identification of a terphenyl derivative that blocks the cell cycle in the G0-G1 phase and induces differentiation in leukemia cells

Journal of Medicinal Chemistry

Volumn 49, Issue 10, 2006, Pages 3012-3018

  Roberti, Marinella ^a   Pizzirani, Daniela ^a   Recanatini, Maurizio ^a   Simoni, Daniele ^b   Grimaudo, Stefania ^c   Di Cristina, Antonietta ^c   Abbadessa, Vincenzo ^c   Gebbia, Nicola ^c   Tolomeo, Manlio ^c  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c UNIVERSITY OF PALERMO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; PHYTOALEXIN; RESVERATROL; STILBENE DERIVATIVE; TERPHENYL DERIVATIVE;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DIFFERENTIATION; CELL STRAIN HL 60; DERIVATIZATION; DRUG IDENTIFICATION; LEUKEMIA CELL; MULTIDRUG RESISTANCE; NONHUMAN; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION; TARGET CELL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DIFFERENTIATION; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; FUSION PROTEINS, BCR-ABL; G0 PHASE; G1 PHASE; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; P-GLYCOPROTEIN; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; TERPHENYL COMPOUNDS;

EID: 33646737506     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm060253o     Document Type: Article

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