Optical imaging of lymph nodes

European Journal of Radiology

Volumn 58, Issue 3, 2006, Pages 390-393

  Wunderbaldinger, Patrick ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

Lymph node; Near infrared flourescence; Optical imaging

Indexed keywords

ENZYME KINETICS; FLUORESCENCE; INFRARED IMAGING; OPTICAL SYSTEMS;

LYMPH NODE; NEAR INFRARED FLOURESCENCE; OPTICAL IMAGING;

MEDICAL IMAGING;

ARTICLE; FLUORESCENCE; HUMAN; IMAGING; LYMPH NODE; LYMPHOGRAPHY; NONHUMAN; OPTICS; PRIORITY JOURNAL; RADIODIAGNOSIS; TECHNIQUE;

ANIMALS; FLUORESCENCE; HUMANS; LYMPH NODES; MICE; SPECTROSCOPY, NEAR-INFRARED;

EID: 33646594149     PISSN: 0720048X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejrad.2005.12.043     Document Type: Article

References (52)

1. Bremer C., Ntziachristos V., and Weissleder R. Optical-based molecular imaging: contrast agents and potential medical applications. Eur Radiol 13 2 (2003) 231-243
2. Ntziachristos V., Bremer C., Graves E.E., Ripoll J., and Weissleder R. In vivo tomographic imaging of near-infrared fluorescent probes. Mol Imaging 1 2 (2002) 82-88
3. Weissleder R., Tung C.H., Mahmood U., and Bogdanov Jr. A. In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol 17 4 (1999) 375-378
4. Weissleder R. Molecular imaging: exploring the next frontier. Radiology 212 3 (1999) 609-614
5. Mahmood U., Tung C.H., Bogdanov Jr. A., and Weissleder R. Near-infrared optical imaging of protease activity for tumor detection. Radiology 213 3 (1999) 866-870
6. Ntziachristos V., Bremer C., and Weissleder R. Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging. Eur Radiol 13 1 (2003) 195-208
7. Weissleder R., and Mahmood U. Molecular imaging. Radiology 219 2 (2001) 316-333
8. Tung C.H., Bredow S., Mahmood U., and Weissleder R. Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging. Bioconjug Chem 10 5 (1999) 892-896
9. Mahmood U., and Weissleder R. Near-infrared optical imaging of proteases in cancer. Mol Cancer Ther 2 5 (2003) 489-496
10. Becker A., Hessenius C., Licha K., et al. Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands. Nat Biotechnol 19 (2001) 327-331
11. Chen J., Tung C.H., Mahmood U., et al. In vivo imaging of proteolytic activity in atherosclerosis. Circulation 105 23 (2002) 2766-2771
12. Wunder A., Schellenberger E., Mahmood U., et al. Methotrexate-induced accumulation of fluorescent annexin V in collagen-induced arthritis. Mol Imaging 4 1 (2005) 1-6
13. Bremer C., Ntziachristos V., Weitkamp B., Theilmeier G., Heindel W., and Weissleder R. Optical imaging of spontaneous breast tumors using protease sensing 'smart' optical probes. Invest Radiol 40 6 (2005) 321-327
14. Chen J., Tung C.H., Allport J.R., Chen S., Weissleder R., and Huang P.L. Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction. Circulation 111 14 (2005) 1800-1805
15. Chen WT, Mahmood U, Weissleder R, Tung CH. Arthritis imaging using a near-infrared fluorescence folate-targeted probe. Arthritis Res Ther 2005;7(2):R310-7.
16. Wunder A., Tung C.H., Muller-Ladner U., Weissleder R., and Mahmood U. In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response. Arthritis Rheum 50 8 (2004) 2459-2465
17. Ntziachristos V., Schellenberger E.A., Ripoll J., et al. Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate. Proc Natl Acad Sci USA 101 33 (2004) 12294-12299
18. Shah K., Jacobs A., Breakefield X.O., and Weissleder R. Molecular imaging of gene therapy for cancer. Gene Ther 11 15 (2004) 1175-1187
19. Kircher M.F., Weissleder R., and Josephson L. A dual fluorochrome probe for imaging proteases. Bioconjug Chem 15 2 (2004) 242-248
20. Josephson L., Mahmood U., Wunderbaldinger P., Tang Y., and Weissleder R. Pan and sentinel lymph node visualization using a near-infrared fluorescent probe. Mol Imaging 2 1 (2003) 18-23
21. Bremer C., Tung C.H., Bogdanov Jr. A., and Weissleder R. Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes. Radiology 222 3 (2002) 814-818
22. Marten K., Bremer C., Khazaie K., et al. Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice. Gastroenterology 122 2 (2002) 406-414
23. Bremer C., Bredow S., Mahmood U., Weissleder R., and Tung C.H. Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model. Radiology 221 2 (2001) 523-529
24. Bremer C., Tung C.H., and Weissleder R. In vivo molecular target assessment of matrix metalloproteinase inhibition. Nat Med 7 6 (2001) 743-748
25. Wunderbaldinger P., Turetschek K., and Bremer C. Near-infrared fluorescence imaging of lymph nodes using a new enzyme sensing activatable macromolecular optical probe. Eur Radiol 13 9 (2003) 2206-2211
26. Tung C.H., Mahmood U., Bredow S., and Weissleder R. In vivo imaging of proteolytic enzyme activity using a novel molecular reporter. Cancer Res 60 17 (2000) 4953-4958
27. Montet X., Ntziachristos V., Grimm J., and Weissleder R. Tomographic fluorescence mapping of tumor targets. Cancer Res 65 14 (2005) 6330-6336
28. Graves E.E., Weissleder R., and Ntziachristos V. Fluorescence molecular imaging of small animal tumor models. Curr Mol Med 4 4 (2004) 419-430
29. Ntziachristos V., Bremer C., Tung C., and Weissleder R. Imaging cathepsin B up-regulation in HT-1080 tumor models using fluorescence-mediated molecular tomography (FMT). Acad Radiol 9 Suppl. 2 (2002) S323-S325
30. Jaffer F.A., and Weissleder R. Molecular imaging in the clinical arena. JAMA 293 7 (2005) 855-862
31. Kelly K., Alencar H., Funovics M., Mahmood U., and Weissleder R. Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide. Cancer Res 64 17 (2004) 6247-6251
32. Godavarty A., Thompson A.B., Roy R., et al. Diagnostic imaging of breast cancer using fluorescence-enhanced optical tomography: phantom studies. J Biomed Opt 9 3 (2004) 488-496
33. Sosnovik D.E., Schellenberger E.A., Nahrendorf M., et al. Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle. Magn Reson Med 54 3 (2005) 718-724
34. Zacharakis G., Ripoll J., Weissleder R., and Ntziachristos V. Fluorescent protein tomography scanner for small animal imaging. IEEE Trans Med Imaging 24 7 (2005) 878-885
35. Ntziachristos V., Bremer C., Graves E.E., Ripoll J., and Weissleder R. In vivo tomographic imaging of near-infrared fluorescent probes. Mol Imaging 1 2 (2002) 82-88
36. Ntziachristos V., Yodh A.G., Schnall M., and Chance B. Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement. Proc Natl Acad Sci USA 97 6 (2000) 2767-2772
37. Schellenberger E.A., Sosnovik D., Weissleder R., and Josephson L. Magneto/optical annexin V, a multimodal protein. Bioconjug Chem 15 5 (2004) 1062-1067
38. Funovics M.A., Weissleder R., and Mahmood U. Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice. Radiology 231 3 (2004) 659-666
39. Josephson L., Kircher M.F., Mahmood U., Tang Y., and Weissleder R. Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes. Bioconjug Chem 13 3 (2002) 554-560
40. Licha K., Debus N., Emig-Vollmer S., et al. Optical molecular imaging of lymph nodes using a targeted vascular contrast agent. J Biomed Opt 10 4 (2005) 41205
41. Soltesz E.G., Kim S., Laurence R.G., et al. Intraoperative sentinel lymph node mapping of the lung using near-infrared fluorescent quantum dots. Ann Thorac Surg 79 1 (2005) 269-277
42. Kim S., Lim Y.T., Soltesz E.G., et al. Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping. Nat Biotechnol 22 1 (2004) 93-97
43. Ntziachristos V., Tung C.H., Bremer C., and Weissleder R. Fluorescence molecular tomography resolves protease activity in vivo. Nat Med 8 7 (2002) 757-760
44. Parungo C.P., Colson Y.L., Kim S.W., et al. Sentinel lymph node mapping of the pleural space. Chest 127 5 (2005) 1799-1804
45. Parungo C.P., Ohnishi S., Kim S.W., et al. Intraoperative identification of esophageal sentinel lymph nodes with near-infrared fluorescence imaging. J Thorac Cardiovasc Surg 129 4 (2005) 844-850
46. Howie A.J., Burnett D., and Crocker J. The distribution of cathepsin B in human tissues. J Pathol 145 (1985) 307-314
47. Qian F., Chan S.J., Gong Q.M., Bajkowski A.S., Steiner D.F., and Frankfarter A. The expression of cathepsin B and other lysosomal proteinases in normal tissue and tumors. Biomed Biochim Acta 50 (1991) 531-540
48. Funovics M.A., Alencar H., Su H.S., Khazaie K., Weissleder R., and Mahmood U. Miniaturized multichannel near infrared endoscope for mouse imaging. Mol Imaging 2 4 (2003) 350-357
49. Luo W., Nguyen F.T., Zysk A.M., et al. Optical biopsy of lymph node morphology using optical coherence tomography. Technol Cancer Res Treat 4 5 (2005) 539-548
50. Wang L., and Shen Q. Optical tomography for biological applications. IEEE Eng Med Biol 17 (1998) 45-56
51. Vargas G., Chan E.K., Barton J.K., Rylander H.G., and Welch A.J. Use of an agent to reduce scattering in skin. Lasers Surg Med 24 (1999) 133-141
52. Tromberg B.J., Shah N., Lanning R., et al. Non-invasive in vivo characterization of breast tumors using photon migration spectroscopy. Neoplasia 2 (2000) 26-40