A functional genomics approach to the mode of action of apratoxin A

Nature Chemical Biology

Volumn 2, Issue 3, 2006, Pages 158-167

  Luesch, Hendrik ^a,e   Chanda, Sumit K ^b   Raya, R Marina ^c,d   DeJesus, Paul D ^b   Orth, Anthony P ^b   Walker, John R ^b   Izpisúa Belmonte, Juan Carlos ^c   Schultz, Peter G ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^d CENTER OF REGENERATIVE MEDICINE IN BARCELONA   (Spain)

^e UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; APRATOXIN A; COMPLEMENTARY DNA; FIBROBLAST GROWTH FACTOR RECEPTOR; STAT3 PROTEIN; UNCLASSIFIED DRUG; DEPSIPEPTIDE; FIBROBLAST GROWTH FACTOR; MESSENGER RNA;

ANGIOGENESIS; APOPTOSIS; ARTICLE; CELL ACTIVITY; CELL CYCLE; CELL CYCLE G1 PHASE; CYTOTOXICITY; DNA DETERMINATION; DRUG ANTAGONISM; GENOMICS; HUMAN; MAMMAL CELL; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ZEBRA FISH; ANIMAL; CELL CULTURE; CELL PROLIFERATION; CONFORMATION; DRUG EFFECT; DRUG RESISTANCE; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; IN VITRO STUDY; METABOLISM; METHODOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PRENATAL DEVELOPMENT; STRUCTURE ACTIVITY RELATION;

CYANOBACTERIA; DANIO RERIO;

ANIMALS; APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; DEPSIPEPTIDES; DRUG RESISTANCE, NEOPLASM; ENDOTHELIAL CELLS; FIBROBLAST GROWTH FACTORS; G1 PHASE; GENE EXPRESSION REGULATION; GENOMICS; HUMANS; MOLECULAR CONFORMATION; PHOSPHORYLATION; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; ZEBRAFISH;

EID: 33646572869     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio769     Document Type: Article

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