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Volumn 40, Issue 11, 2006, Pages 1971-1980

Early thymic T cell development in young transgenic mice overexpressing human Cu/Zn superoxide dismutase, a model of Down syndrome

Author keywords

Cu Zn superoxide dismutase; Down syndrome; Free radicals; Lymph nodes; Reactive oxygen species; Spleen; T lymphocytes; Thymus; Transgenic

Indexed keywords

BROXURIDINE; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOKINE; LIPOCORTIN 5; REACTIVE OXYGEN METABOLITE;

EID: 33646568473     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2006.01.029     Document Type: Article
Times cited : (5)

References (61)
  • 3
    • 0025618405 scopus 로고
    • Precocious aging of the immune system in Down syndrome: alteration of B lymphocytes, T-lymphocyte subsets, and cells with natural killer markers
    • Cossarizza A., Monti D., Montagnani G., Ortolani C., Masi M., Zannotti M., and Franceschi C. Precocious aging of the immune system in Down syndrome: alteration of B lymphocytes, T-lymphocyte subsets, and cells with natural killer markers. Am. J. Med. Genet. Suppl. 7 (1990) 213-218
    • (1990) Am. J. Med. Genet. Suppl. , vol.7 , pp. 213-218
    • Cossarizza, A.1    Monti, D.2    Montagnani, G.3    Ortolani, C.4    Masi, M.5    Zannotti, M.6    Franceschi, C.7
  • 5
    • 0023492605 scopus 로고
    • Altered T-cell subsets and defective T-cell function in young children with Down syndrome (trisomy-21)
    • Noble R.L., and Warren R.P. Altered T-cell subsets and defective T-cell function in young children with Down syndrome (trisomy-21). Immunol. Invest. 16 (1987) 371-382
    • (1987) Immunol. Invest. , vol.16 , pp. 371-382
    • Noble, R.L.1    Warren, R.P.2
  • 8
    • 0034074882 scopus 로고    scopus 로고
    • Partial impairment of immune functions in peripheral blood leukocytes from aged men with Down's syndrome
    • Park E., Alberti J., Mehta P., Dalton A., Sersen E., and Schuller-Levis G. Partial impairment of immune functions in peripheral blood leukocytes from aged men with Down's syndrome. Clin. Immunol. 95 (2000) 62-69
    • (2000) Clin. Immunol. , vol.95 , pp. 62-69
    • Park, E.1    Alberti, J.2    Mehta, P.3    Dalton, A.4    Sersen, E.5    Schuller-Levis, G.6
  • 13
    • 0034578448 scopus 로고    scopus 로고
    • Longevity and the immune response
    • Aspinall R. Longevity and the immune response. Biogerontology 1 (2000) 273-278
    • (2000) Biogerontology , vol.1 , pp. 273-278
    • Aspinall, R.1
  • 16
    • 0031466825 scopus 로고    scopus 로고
    • Thymic aging and T-cell regeneration
    • Mackall C.L., and Gress R.E. Thymic aging and T-cell regeneration. Immunol. Rev. 160 (1997) 91-102
    • (1997) Immunol. Rev. , vol.160 , pp. 91-102
    • Mackall, C.L.1    Gress, R.E.2
  • 17
    • 0031205689 scopus 로고    scopus 로고
    • Thymic involution
    • Turke P.W. Thymic involution. Immunol. Today 18 (1997) 407
    • (1997) Immunol. Today , vol.18 , pp. 407
    • Turke, P.W.1
  • 18
    • 0036253339 scopus 로고    scopus 로고
    • Role of thymic stromal cell dysfunction in the thymic involution of mammary tumor-bearing mice
    • Sun Q.L., Charyulu V., Lobo D., and Lopez D.M. Role of thymic stromal cell dysfunction in the thymic involution of mammary tumor-bearing mice. Anticancer Res. 22 (2002) 91-96
    • (2002) Anticancer Res. , vol.22 , pp. 91-96
    • Sun, Q.L.1    Charyulu, V.2    Lobo, D.3    Lopez, D.M.4
  • 20
    • 0029983348 scopus 로고    scopus 로고
    • Transgenic mice overexpressing the human Cu/Zn-SOD gene: ultrastructural studies of a premature thymic involution model of Down's syndrome (trisomy 21)
    • Nabarra B., Casanova M., Paris D., Nicole A., Toyama K., Sinet P.M., Ceballos I., and London J. Transgenic mice overexpressing the human Cu/Zn-SOD gene: ultrastructural studies of a premature thymic involution model of Down's syndrome (trisomy 21). Lab. Invest. 74 (1996) 617-626
    • (1996) Lab. Invest. , vol.74 , pp. 617-626
    • Nabarra, B.1    Casanova, M.2    Paris, D.3    Nicole, A.4    Toyama, K.5    Sinet, P.M.6    Ceballos, I.7    London, J.8
  • 21
    • 0031011194 scopus 로고    scopus 로고
    • Premature thymic involution, observed at the ultrastructural level, in two lineages of human-SOD-1 transgenic mice
    • Nabarra B., Casanova M., Paris D., Paly E., Toyoma K., Ceballos I., and London J. Premature thymic involution, observed at the ultrastructural level, in two lineages of human-SOD-1 transgenic mice. Mech. Ageing Dev. 96 (1997) 59-73
    • (1997) Mech. Ageing Dev. , vol.96 , pp. 59-73
    • Nabarra, B.1    Casanova, M.2    Paris, D.3    Paly, E.4    Toyoma, K.5    Ceballos, I.6    London, J.7
  • 22
    • 0028839912 scopus 로고
    • Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: implications for Down syndrome
    • Peled-Kamar M., Lotem J., Okon E., Sachs L., and Groner Y. Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: implications for Down syndrome. EMBO J. 14 (1995) 4985-4993
    • (1995) EMBO J. , vol.14 , pp. 4985-4993
    • Peled-Kamar, M.1    Lotem, J.2    Okon, E.3    Sachs, L.4    Groner, Y.5
  • 23
  • 24
    • 0036776370 scopus 로고    scopus 로고
    • Regulation of thymocyte differentiation: pre-TCR signals and beta-selection
    • Michie A.M., and Zuniga-Pflucker J.C. Regulation of thymocyte differentiation: pre-TCR signals and beta-selection. Semin. Immunol. 14 (2002) 311-323
    • (2002) Semin. Immunol. , vol.14 , pp. 311-323
    • Michie, A.M.1    Zuniga-Pflucker, J.C.2
  • 26
    • 0031111907 scopus 로고    scopus 로고
    • Age-associated thymic atrophy in the mouse is due to a deficiency affecting rearrangement of the TCR during intrathymic T cell development
    • Aspinall R. Age-associated thymic atrophy in the mouse is due to a deficiency affecting rearrangement of the TCR during intrathymic T cell development. J. Immunol. 158 (1997) 3037-3045
    • (1997) J. Immunol. , vol.158 , pp. 3037-3045
    • Aspinall, R.1
  • 27
    • 0041819789 scopus 로고    scopus 로고
    • Development of thymic microenvironments in vitro is oxygen-dependent and requires permanent presence of T-cell progenitors
    • Germeraad W.T., Kawamoto H., Itoi M., Jiang Y., Amagai T., Katsura Y., and van Ewijk W. Development of thymic microenvironments in vitro is oxygen-dependent and requires permanent presence of T-cell progenitors. J. Histochem. Cytochem. 51 (2003) 1225-1235
    • (2003) J. Histochem. Cytochem. , vol.51 , pp. 1225-1235
    • Germeraad, W.T.1    Kawamoto, H.2    Itoi, M.3    Jiang, Y.4    Amagai, T.5    Katsura, Y.6    van Ewijk, W.7
  • 28
    • 3242747324 scopus 로고    scopus 로고
    • Regulation of thymus size by competition for stromal niches among early T cell progenitors
    • Prockop S.E., and Petrie H.T. Regulation of thymus size by competition for stromal niches among early T cell progenitors. J. Immunol. 173 (2004) 1604-1611
    • (2004) J. Immunol. , vol.173 , pp. 1604-1611
    • Prockop, S.E.1    Petrie, H.T.2
  • 29
    • 0031570746 scopus 로고    scopus 로고
    • Early steps in T cell development are affected by aging
    • Thoman M.L. Early steps in T cell development are affected by aging. Cell. Immunol. 178 (1997) 117-123
    • (1997) Cell. Immunol. , vol.178 , pp. 117-123
    • Thoman, M.L.1
  • 30
    • 0036582215 scopus 로고    scopus 로고
    • T-cell development and the CD4-CD8 lineage decision
    • Germain R.N. T-cell development and the CD4-CD8 lineage decision. Nat. Rev. Immunol. 2 (2002) 309-322
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 309-322
    • Germain, R.N.1
  • 32
    • 0027375226 scopus 로고
    • T cell development: new approaches
    • Merkenschlager M., and Fisher A.G. T cell development: new approaches. Leukemia 7 Suppl. 2 (1993) S40-S44
    • (1993) Leukemia , vol.7 , Issue.SUPPL. 2
    • Merkenschlager, M.1    Fisher, A.G.2
  • 34
    • 0033120586 scopus 로고    scopus 로고
    • CD69 expression discriminates MHC-dependent and-independent stages of thymocyte positive selection
    • Hare K.J., Jenkinson E.J., and Anderson G. CD69 expression discriminates MHC-dependent and-independent stages of thymocyte positive selection. J. Immunol. 162 (1999) 3978-3983
    • (1999) J. Immunol. , vol.162 , pp. 3978-3983
    • Hare, K.J.1    Jenkinson, E.J.2    Anderson, G.3
  • 36
    • 0016272750 scopus 로고
    • Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase
    • Marklund S., and Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem. 47 (1974) 469-474
    • (1974) Eur. J. Biochem. , vol.47 , pp. 469-474
    • Marklund, S.1    Marklund, G.2
  • 37
    • 0020332460 scopus 로고
    • Thymus morphology in Down's syndrome
    • Medvedev N., and Popova E.D. Thymus morphology in Down's syndrome. Arkh. Patol. 44 (1982) 27-30
    • (1982) Arkh. Patol. , vol.44 , pp. 27-30
    • Medvedev, N.1    Popova, E.D.2
  • 38
    • 0036373780 scopus 로고    scopus 로고
    • CuZn-superoxide dismutase in human thymus: immunocytochemical localisation and secretion in thymus-derived epithelial and fibroblast cell lines
    • Cimini V., Ruggiero G., Buonomo T., Seru R., Sciorio S., Zanzi C., Santangelo F., and Mondola P. CuZn-superoxide dismutase in human thymus: immunocytochemical localisation and secretion in thymus-derived epithelial and fibroblast cell lines. Histochem. Cell. Biol. 118 (2002) 163-169
    • (2002) Histochem. Cell. Biol. , vol.118 , pp. 163-169
    • Cimini, V.1    Ruggiero, G.2    Buonomo, T.3    Seru, R.4    Sciorio, S.5    Zanzi, C.6    Santangelo, F.7    Mondola, P.8
  • 39
    • 0025810875 scopus 로고
    • Hypothesis: involution of the thymus with aging-Programmed and beneficial
    • Aronson M. Hypothesis: involution of the thymus with aging-Programmed and beneficial. Thymus 18 (1991) 7-13
    • (1991) Thymus , vol.18 , pp. 7-13
    • Aronson, M.1
  • 40
    • 0028059474 scopus 로고
    • Understanding the mechanism of the age-change of thymic function to promote T cell differentiation
    • Hirokawa K., Utsuyama M., Kasai M., Kurashima C., Ishijima S., and Zeng Y.X. Understanding the mechanism of the age-change of thymic function to promote T cell differentiation. Immunol. Lett. 40 (1994) 269-277
    • (1994) Immunol. Lett. , vol.40 , pp. 269-277
    • Hirokawa, K.1    Utsuyama, M.2    Kasai, M.3    Kurashima, C.4    Ishijima, S.5    Zeng, Y.X.6
  • 41
    • 0034120175 scopus 로고    scopus 로고
    • Early block in maturation is associated with thymic involution in mammary tumor-bearing mice
    • Adkins B., Charyulu V., Sun Q.L., Lobo D., and Lopez D.M. Early block in maturation is associated with thymic involution in mammary tumor-bearing mice. J. Immunol. 164 (2000) 5635-5640
    • (2000) J. Immunol. , vol.164 , pp. 5635-5640
    • Adkins, B.1    Charyulu, V.2    Sun, Q.L.3    Lobo, D.4    Lopez, D.M.5
  • 43
    • 0030827915 scopus 로고    scopus 로고
    • Ontogeny of the immune system: gamma/delta and alpha/beta T cells migrate from thymus to the periphery in alternating waves
    • Dunon D., Courtois D., Vainio O., Six A., Chen C.H., Cooper M.D., Dangy J.P., and Imhof B.A. Ontogeny of the immune system: gamma/delta and alpha/beta T cells migrate from thymus to the periphery in alternating waves. J. Exp. Med. 186 (1997) 977-988
    • (1997) J. Exp. Med. , vol.186 , pp. 977-988
    • Dunon, D.1    Courtois, D.2    Vainio, O.3    Six, A.4    Chen, C.H.5    Cooper, M.D.6    Dangy, J.P.7    Imhof, B.A.8
  • 44
    • 0032790221 scopus 로고    scopus 로고
    • - thymocytes and its implication in the late stage of thymocyte development
    • - thymocytes and its implication in the late stage of thymocyte development. Immunology 97 (1999) 665-671
    • (1999) Immunology , vol.97 , pp. 665-671
    • Ge, Q.1    Chen, W.F.2
  • 45
    • 0035371529 scopus 로고    scopus 로고
    • Effect of overexpression of human Cu/Zn-SOD on activation-induced lymphocyte proliferation and apoptosis
    • Pahlavani M.A., Mele J.F., and Richardson A. Effect of overexpression of human Cu/Zn-SOD on activation-induced lymphocyte proliferation and apoptosis. Free Radic. Biol. Med. 30 (2001) 1319-1327
    • (2001) Free Radic. Biol. Med. , vol.30 , pp. 1319-1327
    • Pahlavani, M.A.1    Mele, J.F.2    Richardson, A.3
  • 47
    • 0037415559 scopus 로고    scopus 로고
    • + thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection
    • + thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection. J. Exp. Med. 197 (2003) 363-373
    • (2003) J. Exp. Med. , vol.197 , pp. 363-373
    • Liu, X.1    Adams, A.2    Wildt, K.F.3    Aronow, B.4    Feigenbaum, L.5    Bosselut, R.6
  • 48
    • 0035889887 scopus 로고    scopus 로고
    • Inefficient ZAP-70 phosphorylation and decreased thymic selection in vivo result from inhibition of NF-kappaB/Rel
    • Mora A.L., Stanley S., Armistead W., Chan A.C., and Boothby M. Inefficient ZAP-70 phosphorylation and decreased thymic selection in vivo result from inhibition of NF-kappaB/Rel. J. Immunol. 167 (2001) 5628-5635
    • (2001) J. Immunol. , vol.167 , pp. 5628-5635
    • Mora, A.L.1    Stanley, S.2    Armistead, W.3    Chan, A.C.4    Boothby, M.5
  • 49
    • 0035122043 scopus 로고    scopus 로고
    • SOD1 down-regulates NF-kappaB and c-Myc expression in mice after transient focal cerebral ischemia
    • Huang C.Y., Fujimura M., Noshita N., Chang Y.Y., and Chan P.H. SOD1 down-regulates NF-kappaB and c-Myc expression in mice after transient focal cerebral ischemia. J. Cereb. Blood Flow Metab. 21 (2001) 163-173
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , pp. 163-173
    • Huang, C.Y.1    Fujimura, M.2    Noshita, N.3    Chang, Y.Y.4    Chan, P.H.5
  • 50
    • 0036892743 scopus 로고    scopus 로고
    • Oxidative modulation of nuclear factor-kappaB in human cells expressing mutant fALS-typical superoxide dismutases
    • Casciati A., Ferri A., Cozzolino M., Celsi F., Nencini M., Rotilio G., and Carri M.T. Oxidative modulation of nuclear factor-kappaB in human cells expressing mutant fALS-typical superoxide dismutases. J. Neurochem. 83 (2002) 1019-1029
    • (2002) J. Neurochem. , vol.83 , pp. 1019-1029
    • Casciati, A.1    Ferri, A.2    Cozzolino, M.3    Celsi, F.4    Nencini, M.5    Rotilio, G.6    Carri, M.T.7
  • 51
    • 2942529066 scopus 로고    scopus 로고
    • Reactive oxygen species in immune responses
    • Grisham M.B. Reactive oxygen species in immune responses. Free Radic. Biol. Med. 36 (2004) 1479-1480
    • (2004) Free Radic. Biol. Med. , vol.36 , pp. 1479-1480
    • Grisham, M.B.1
  • 52
    • 2942588874 scopus 로고    scopus 로고
    • Regulation of T-cell apoptosis by reactive oxygen species
    • Hildeman D.A. Regulation of T-cell apoptosis by reactive oxygen species. Free Radic. Biol. Med. 36 (2004) 1496-1504
    • (2004) Free Radic. Biol. Med. , vol.36 , pp. 1496-1504
    • Hildeman, D.A.1
  • 54
    • 0037107997 scopus 로고    scopus 로고
    • Copper/zinc superoxide dismutase overexpression promotes survival of cortical neurons exposed to neurotoxins in vitro
    • Borg J., and London J. Copper/zinc superoxide dismutase overexpression promotes survival of cortical neurons exposed to neurotoxins in vitro. J. Neurosci. Res. 70 (2002) 180-189
    • (2002) J. Neurosci. Res. , vol.70 , pp. 180-189
    • Borg, J.1    London, J.2
  • 55
    • 0035074278 scopus 로고    scopus 로고
    • Astrocytes overexpressing Cu,Zn superoxide dismutase have increased resistance to oxidative injury
    • Chen Y., Chan P.H., and Swanson R.A. Astrocytes overexpressing Cu,Zn superoxide dismutase have increased resistance to oxidative injury. Glia 33 (2001) 343-347
    • (2001) Glia , vol.33 , pp. 343-347
    • Chen, Y.1    Chan, P.H.2    Swanson, R.A.3
  • 56
    • 0037335444 scopus 로고    scopus 로고
    • Overexpression of copper/zinc superoxide dismutase in transgenic mice protects against neuronal cell death after transient focal ischemia by blocking activation of the Bad cell death signaling pathway
    • Saito A., Hayashi T., Okuno S., Ferrand-Drake M., and Chan P.H. Overexpression of copper/zinc superoxide dismutase in transgenic mice protects against neuronal cell death after transient focal ischemia by blocking activation of the Bad cell death signaling pathway. J. Neurosci. 23 (2003) 1710-1718
    • (2003) J. Neurosci. , vol.23 , pp. 1710-1718
    • Saito, A.1    Hayashi, T.2    Okuno, S.3    Ferrand-Drake, M.4    Chan, P.H.5
  • 57
    • 0031661220 scopus 로고    scopus 로고
    • Copper/zinc superoxide dismutase transgenic brain accumulates hydrogen peroxide after perinatal hypoxia ischemia
    • Fullerton H.J., Ditelberg J.S., Chen S.F., Sarco D.P., Chan P.H., Epstein C.J., and Ferriero D.M. Copper/zinc superoxide dismutase transgenic brain accumulates hydrogen peroxide after perinatal hypoxia ischemia. Ann. Neurol. 44 (1998) 357-364
    • (1998) Ann. Neurol. , vol.44 , pp. 357-364
    • Fullerton, H.J.1    Ditelberg, J.S.2    Chen, S.F.3    Sarco, D.P.4    Chan, P.H.5    Epstein, C.J.6    Ferriero, D.M.7
  • 58
    • 0033955710 scopus 로고    scopus 로고
    • Differing effects of copper,zinc superoxide dismutase overexpression on neurotoxicity elicited by nitric oxide, reactive oxygen species, and excitotoxins
    • Ying W., Anderson C.M., Chen Y., Stein B.A., Fahlman C.S., Copin J.C., Chan P.H., and Swanson R.A. Differing effects of copper,zinc superoxide dismutase overexpression on neurotoxicity elicited by nitric oxide, reactive oxygen species, and excitotoxins. J. Cereb. Blood Flow Metab. 20 (2000) 359-368
    • (2000) J. Cereb. Blood Flow Metab. , vol.20 , pp. 359-368
    • Ying, W.1    Anderson, C.M.2    Chen, Y.3    Stein, B.A.4    Fahlman, C.S.5    Copin, J.C.6    Chan, P.H.7    Swanson, R.A.8
  • 59
    • 0036407338 scopus 로고    scopus 로고
    • The modulation of cellular susceptibility to oxidative stress: protective and destructive actions of Cu, Zn-superoxide dismutase
    • Xing J., Yu Y., and Rando T.A. The modulation of cellular susceptibility to oxidative stress: protective and destructive actions of Cu, Zn-superoxide dismutase. Neurobiol. Dis. 10 (2002) 234-246
    • (2002) Neurobiol. Dis. , vol.10 , pp. 234-246
    • Xing, J.1    Yu, Y.2    Rando, T.A.3
  • 60
    • 0026444321 scopus 로고
    • Defects in thymocyte differentiation and thymocyte-stromal interactions in the trisomy 16 mouse
    • Ewart J.L., and Auerbach R. Defects in thymocyte differentiation and thymocyte-stromal interactions in the trisomy 16 mouse. Dev. Immunol. 2 (1992) 215-226
    • (1992) Dev. Immunol. , vol.2 , pp. 215-226
    • Ewart, J.L.1    Auerbach, R.2


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