Host defence peptides from invertebrates - emerging antimicrobial strategies

Immunobiology

Volumn 211, Issue 4, 2006, Pages 315-322

  Hancock, Robert E W ^a   Brown, Kelly L ^a   Mookherjee, Neeloffer ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Antibiotics; Antimicrobial peptides; Cationic peptides; Innate immunity; Invertebrate immunity

Indexed keywords

ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; CATHELICIDIN; CATION; DEFENSIN; HELIOMYCIN DERIVATIVE; IMMUNOMODULATING AGENT; PATTERN RECOGNITION RECEPTOR; PEPTIDE DERIVATIVE; POLYPEPTIDE ANTIBIOTIC AGENT; POLYPHEMUSIN; SAPECIN B DERIVATIVE; SERINE PROTEINASE; SYNTHETIC PEPTIDE; TACHYCITIN; TACHYPLESIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTIVIRAL ACTIVITY; CANDIDIASIS; HOST PATHOGEN INTERACTION; HOST RESISTANCE; IMMUNOMODULATION; INFECTION; INVERTEBRATE; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECONDARY STRUCTURE; REVIEW; SEPSIS;

EID: 33646532402     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2005.10.017     Document Type: Review

References (56)

1. Bachère E., Gueguen Y., Gonzalez M., De Lorgeril J., Garnier J., and Romestand B. Insights into the antimicrobial defense of marine invertebrates: the penaeid shrimps and the oyster Crassostrea gigas. Immunol. Rev. 198 (2004) 149-168
2. Belvin M.P., and Anderson K.V. A conserved signalling pathway: the Drosophila Toll-dorsal pathway. Annu. Rev. Cell Dev. Biol. 12 (1996) 393-416
3. Bowdish D.M., Davidson D.J., Lau Y.E., Lee K., Scott M.G., and Hancock R.E.W. Impact of LL-37 on anti-infective immunity. J. Leukoc. Biol. 77 (2005) 451-459
4. Bulet P., Stocklin R., and Menin L. Antimicrobial peptides: from invertebrates to vertebrates. Immunol. Rev. 198 (2004) 169-184
5. Cho J.H., Homma K., Kanegasaki S., and Nato S. Activation of human neutrophils by a synthetic antimicrobial peptide, KLKLLLLLKLK-NH2, via cell surface calreticulin. Eur. J. Biochem. 266 (1999) 878-885
6. Dimarcq J.L., Keppi E., Dunbar B., Lambert J., Reicchart J.M., and Hoffmann D. Insect immunity. Purification and characterization of a family of novel inducible antibacterial proteins from immunized larvae of dipteran Phormia terranovae and complete amino acid sequence. Eur. J. Biochem. 171 (1988) 17-22
7. Engstrom Y. Insect immune gene regulation. In: Brey P.T., and Hultmark D. (Eds). Molecular Mechanism of Immune Responses In Insects (1998), Chapman and Hall, London 211-244
8. Finlay B.B., and Hancock R.E.W. Can innate immunity be enhanced to treat microbial infections?. Nat. Rev. Microbiol. 2 (2004) 497-504
9. Gough M., Hancock R.E.W., and Kelly N.M. Antiendotoxin activity of cationic peptide antimicrobial agents. Infect. Immun. 64 (1996) 4922-4927
10. Hancock R.E.W., and Chapple D.S. Peptide antibiotics. Antimicrob. Agents Chemother. 43 (1999) 1317-1323
11. Hancock R.E.W., and Diamond G. The role of cationic antimicrobial peptides in innate host defences. Trends Microbiol 9 (2000) 402-410
12. Hancock R.E.W., and Patrzykat A. Clinical development of cationic antimicrobial peptides: from natural to novel antibiotics. Curr. Drug Targets 2 (2002) 79-83
13. Hancock R.E.W., and Rozek A. Role of membranes in the activities of antimicrobial cationic peptides. FEMS Microbiol. Lett. 206 (2002) 143-149
14. Hetru C., Hoffmann J.A., and Hancock R.E.W. Insect cationic antimicrobial peptides. In: Dutton C., Haxell M., McArthur H.I., and Wax R. (Eds). Peptide Antibiotics: Discovery, Modes of Action and Applications (2000), Marcel Dekker, NY I 1
15. Hilpert K., Volkmer-Engert R., Walter T., and Hancock R.E.W. High-throughput generation of small antibacterial peptides with improved activity. Nat. Biotech. 23 (2005) 1008-1012
16. Hirakura Y., Kobayashi S., and Matsuzaki M. Specific interactions of the antimicrobial peptide cyclic B-sheet tachyplesin I with lipopolysaccharides. Biochim. Biophys. Acta 1562 (2002) 32-36
17. Hoffmann J.A. The immune response of Drosophila. Nature 426 (2003) 33-38
18. Hoffmann J.A. Primitive immune systems. Immunol. Rev. 198 (2004) 5-9
19. Hoffmann J.A., and Reichhart J. Drosophila innate immunity: an evolutionary perspective. Nat. Immunol 3 (2002) 121-126
20. Hong R.W., Shchepetov M., Weiser J.N., and Axelsen P.H. Transcriptional profile of the Escherichia coli response to the antimicrobial insect peptide cecropin A. Antimicrob. Agents Chemother. 47 (2003) 1-6
21. Imler J.L., and Hoffmann J.A. Signaling mechanism in the antimicrobial defense of Drosophila. Curr. Opin. Microbiol. 3 (2000) 16-22
22. Iwanaga S., and Kawabata S. Evolution and phylogeny of defense molecules associated with innate immunity in horseshoe crab. Front. Biosci. 3 (1998) D973-D984
23. Iwanaga S., and Lee B.L. Recent advances in the innate immunity of invertebrate animals. J. Biochem. Mol. Biol. 38 (2005) 128-150
24. Iwanaga S., Kawabata S., and Muta T. New types of clotting factors and defense molecules found in horseshoe crab hemolymph: their structure and functions. J. Biochem. 123 (1998) 1-15
25. Kragol G., Lovas S., Varadi G., Condie B.A., Hoffmann R., and Otvos Jr. L. The antibacterial peptide pyrrhocoricin inhibits the ATPase actions of DnaK and prevents chaperone-assisted protein folding. Biochemistry 40 (2001) 3016-3026
26. Lamberty M., Caille A., Landon C., Tassin-Moindrot S., Hetru C., Bulet P., and Vovelle F. Solution structures of the antifungal heliomicin and a selected variant with both antibacterial and antifungal activities. Biochemistry 40 (2001) 11995-12003
27. Lee Y.J., Chung T.J., Park C.W., Hanh Y.S., Chung J.H., Lee B.L., Han D.M., Jung Y.H., Kim S., and Lee Y.H. Structure and expression of the tenecin 3 gene in Tenebrio molitor. Biochem. Biophys. Res. Commun. 218 (1996) 6-11
28. Lehrer R.I., and Ganz T. Antimicrobial peptides in mammalian and insect host defense. Curr. Opin. Immunol. 11 (1999) 23-27
29. Lemaitre B., Nicholas E., Michaut L., Reichhart J.M., and Hoffmann J.A. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86 (1996) 973-983
30. Luders T., Birkemo G.A., Fimland G., Nissen-Meyer J., and Nes I.F. Strong synergy between a eukaryotic antimicrobial peptide and bacteriocins from lactic acid bacteria. Appl. Environ. Microbiol. 69 (2003) 1797-1799
31. Masuda M., Nakashima H., Ueda T., Naba H., Ikoma R., Otaka A., Terakawa Y., Tamamura H., Ibuka T., and Murakami T. A novel anti-HIV synthetic peptide, T-22 ([Tyr5,12,Lys7]-polyphemusin II). Biochem. Biophys. Res. Commun. 189 (1992) 845-850
32. Mitta G., Hubert F., Noel T., and Roch P. Myticin a novel cysteine-rich antimicrobial peptide isolated from hemocytes and plasma of mussel Mytilus galloprovincialis. Eur. J. Biochem. 264 (1999) 1-9
33. Mookherjee N., Brown K.L., Bowdish D.M., Doria S., Falsafi R., Hokamp K., Roche F.M., Mu R., Doho G.H., Pistolic J., Powers J.P., Bryan J., Brinkman F.S., and Hancock R.E. Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37. J. Immunol. 176 (2006) 2455-2464
34. Morvan A., Iwanaga S., Comps M., and Bachere E. In vitro activity of the Limulus antimicrobial peptide tachyplesin I on marine bivalve pathogens. J. Invertebr. Pathol. 69 (1997) 177-182
35. Nakajima Y., Alvarez-Bravo J., Cho J.H., Homma K.I., Kanegasaki S., and Natori S. Chemotherapeutic activity of synthetic antimicrobial peptides: correlation between chemotherapeutic activity and neutrophil-activating activity. FEBS Lett 415 (1997) 64-66
36. Nakamura T., Furunaka H., Miyata T., Tokunaga F., Muta T., and Iwanaga S. Tachyplesin, a class of antimicrobial peptide from the hemocytes of the horseshoe crab (Tachypleus tridentatus). J. Biol. Chem. 263 (1988) 16709-16713
37. Ohashi M.K., Niwa T., Nakamura T., Morita T., and Iwanaga S. Anti-LPS factor in the horseshoe crab, Tachypleus tridentatus: its hemolytic activity on the red blood cell sensitized with lipopolysaccharide. FEBS Lett 176 (1984) 207-210
38. Patrzykat A., Friedrich C.L., Zhang L., Mendoza V., and Hancock R.E.W. Sublethal Concentrations of pleurocidin-derived antimicrobial peptides inhibit macromolecular synthesis in E. coli. Antimicrob. Agents Chemother. 46 (2002) 605-614
39. Powers J.P., and Hancock R.E.W. The relationship between peptide structure and antibacterial activity. Peptides 24 (2004) 1681-1691
40. Reed W.A., Elzer P.H., Enright F.M., Jaynes J.M., Morrey J.D., and White K.L. Interleukin 2 promoter/enhancer controlled expression of a synthetic cecropin-class lytic peptide in transgenic mice and subsequent resistance to Brucella abortus. Transgenic Res 6 (1997) 337-347
41. Salzet M. Vertebrate innate immunity resembles a mosaic of invertebrate immune responses. Trends Immunol 22 (2001) 285-288
42. Salzet M. Neuroimmunology of opioids from invertebrates to humans. Neuroendocrinol. Letts. 22 (2001) 467-474
43. Salzet M. Antimicrobial peptides are signaling molecules. Trends Immunol 23 (2002) 283-284
44. Scott M.G., Rosenberger C.M., Gold M.R., Finlay B.B., and Hancock R.E.W. An α-helical cationic antimicrobial peptide selectively modulates macrophage response to LPS and directly alters macrophage gene expression. J. Immunol. 165 (2000) 3358-3365
45. Scott M.G., Davidson D.J., Gold M.R., Bowdish D.M., and Hancock R.E.W. The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses. J. Immunol. 169 (2002) 3883-3891
46. Steiner H., Hultmark D., Engstrom A., Bennich H., and Boman H.G. Sequence and specificity of two antimicrobial proteins in insect immunity. Nature 292 (1981) 246-248
47. Tan N.S., Ho B., and Ding J.L. High affinity LPS binding domain(s) in recombinant Factor C of a horseshoe crab neutralizes LPS-induced lethality. FASEB J 14 (2000) 859-887
48. Tan N.S., Ng M.L.P., Yau Y.H., Chong P.K.W., Ho B., and Ding J.L. Definition of endotoxin binding sites in horseshoe crab Factor C recombinant sushi proteins and neutralization of endotoxin by sushi peptides. FASEB J 14 (2000) 1801-1813
49. Tanaka S.T., Nakamura T., Morita T., and Iwanaga S. Limulus anti-LPS factor: an anticoagulant which inhibits the endotoxin-mediated activation of Limulus coagulation system. Biochem. Biophys. Res. Commun. 105 (1982) 717-723
50. Tincu J.A., and Taylor S.W. Antimicrobial peptides from marine invertebrate. Antimicrob. Agents Chemother. 48 (2004) 3645-3654
51. Vallespi M.G., Glaria L.A., Reyes O., Garray H.E., Ferrero J., and Araña M.J. A Limulus antilipopolysaccharide factor-derived peptide exhibits a new immunological activity with potential applicability in infectious diseases. Clin. Diagn. Lab. Immunol. 7 (2000) 669-675
52. Vallespi M.G., Alvarez-Obregon J.C., Rodriguez-Alonso I., Montero T., Garay H., Reyes O., and Arana M.J. A Limulus anti-LPS factor-derived peptide modulates cytokine gene expression and promotes resolution of bacterial acute infection in mice. Int. Immunopharmacol. 3 (2003) 247-256
53. Wang R., Lee S.Y., Cerenius L., and Söderhäll K. Properties of the prophenoloxidase activating enzyme of the freshwater crayfish, Pacifastacus leniusculus. Eur. J. Biochem. 268 (2001) 895-902
54. Zasloff M. Antimicrobial peptides of multicellular organisms. Nature 415 (2002) 389-395
55. Zhang L., and Falla T.J. Cationic antimicrobial peptides - an update. Expert Opin. Invest Drugs 9 (2004) 1723-1729
56. Zhang L., Scott M.G., Yan H., Mayer L.D., and Hancock R.E.W. Interaction of polyphemusin I and structural analogs with bacterial membranes, lipopolysaccharide, and lipid monolayers. Biochemistry 39 (2000) 14504-14514