High-throughput generation of small antibacterial peptides with improved activity

Nature Biotechnology

Volumn 23, Issue 8, 2005, Pages 1008-1012

  Hilpert, Kai ^a   Volkmer Engert, Rudolf ^b   Walter, Tess ^a   Hancock, Robert E W ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBIOTICS; ENZYMES; ESCHERICHIA COLI; OPTIMIZATION; SYNTHESIS (CHEMICAL);

ANTIBACTERIAL PEPTIDES; HIGH-THROUGHPUT METHODS; MINIMAL INHIBITORY CONCENTRATIONS (MIC); SPECTRUM ACITIVTY;

POLYPEPTIDES;

ANTIBIOTIC AGENT; BACTENECIN; CELLULOSE; DALFOPRISTIN PLUS QUINUPRISTIN; DAPTOMYCIN; GLYCOLIPID; LINEZOLID; LUCIFERASE; OXAZOLIDINONE DERIVATIVE; PROTEIN BAC2A; PROTEIN BAC8A; PROTEIN BAC8B; PROTEIN BAC8C; PROTEIN BAC8D; PROTEIN G1; PROTEIN G12; PROTEIN G2; PROTEIN K7; PROTEIN P7; PROTEIN R11; PROTEIN R2; PROTEIN R3; PROTEIN R5; PROTEIN SUB2; PROTEIN SUB3; PROTEIN SUB5; PROTEIN W10; PROTEIN W3; STREPTOGRAMIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AMINO ACID SUBSTITUTION; ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG DEVELOPMENT; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HIGH THROUGHPUT SCREENING; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BIOLOGICAL ASSAY; CELL CULTURE TECHNIQUES; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PEPTIDES, CYCLIC; PSEUDOMONAS AERUGINOSA; RECOMBINANT PROTEINS;

BOVINAE; ESCHERICHIA COLI; NEGIBACTERIA; POSIBACTERIA; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

EID: 23444451770     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt1113     Document Type: Article

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