Definition of endotoxin binding sites in horseshoe crab Factor C recombinant sushi proteins and neutralization of endotoxin by sushi peptides

FASEB Journal

Volumn 14, Issue 12, 2000, Pages 1801-1813

  Tan, N S ^a   Ng, M L P ^a   Yau, Y H ^a   Chong, P K W ^a   Ho, B ^a   Ding, J L ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Drosophila S2 cells; Limulus amebocyte lysate; Lipid A; LPS

Indexed keywords

ENDOTOXIN; GLYCOPROTEIN; LIPID A; LIPOPOLYSACCHARIDE; PEPTIDE DERIVATIVE; RECOMBINANT FACTOR C; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONFORMATIONAL TRANSITION; CYTOKINE RELEASE; DISULFIDE BOND; HUMAN; HUMAN CELL; LIMULUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN STRUCTURE;

DECAPODA (CRUSTACEA); LIMULUS; MEROSTOMATA;

EID: 0033813364     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.99-0866com     Document Type: Article

References (35)

1. The molecular pathogenesis of endotoxic shock and organ failure
2. Molecular basis for structural diversity in the core regions of the lipopolysaccharides of Escherichia coli and Salmonella enterica
3. Molecular structure of lipid A, the endotoxic center of bacterial lipopolysaccharides
4. Clotting and immune defense in Limulidae
5. Molecular cloning and sequence analysis of Factor C cDNA from the Singapore horseshoe crab. Carcinoscorpius rotundicauda
6. Limulus factor C. An endotoxin-sensitive serine protease zymogen with a mosaic structure of complement-like, epidermal growth factor-like, and lectin-like domains
7. High affinity LPS binding domain(s) in recombinant Factor C of a horseshoe crab neutralizes LPS-induced lethality
8. Improved green fluorescent protein by molecular evolution using DNA shuffling
9. Cell lines derived from late embryonic stages of Drosophila melanogaster
10. CLAMP: A biosensor kinetic data analysis program
11. The solution structure of the active domain of CAP18 - A lipopolysaccharide binding protein from rabbit leukocytes
12. The combinations of haemoglobin with oxygen and with carbon monoxide
13. Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester
14. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture
15. Comparison of MTT, XTT, and a novel tetrazolium compound MTS for in vitro proliferation and chemosensitivity assays
16. Galactosamine-induced sensitization to the lethal effects of endotoxin
17. Nonparametric estimation from incomplete observations
18. Agents that increase the permeability of the outer membrane
19. Lipopolysaccharide-sensitive serine-protease zymogen (factor C) found in Limulus hemocytes. Isolation and characterization
20. Molecular mechanism of hemolymph clotting system in Limulus
21. The limulus clotting reaction
22. Cloning of the cDNA of a human neutrophil bactericidal protein
23. Isolation and biological activities of Limulus anticoagulant (anti-LPS factor) which interacts with lipopolysaccharide (LPS)
24. Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14
25. Intracellular serine-protease zymogen, Factor C, from horseshoe crab hemocytes: Its activation by synthetic lipid A analogues and acidic phospholipids
26. Identification and characterization of novel antimicrobial decapeptides generated by combinatorial chemistry
27. Competition between rBPI23, a recombinant fragment of bactericidal/permeability-increasing protein, and lipopolysaccharide (LPS)-binding protein for binding to LPS and gram-negative bacteria
28. Preferential binding of the neutrophil cytoplasmic granule-derived bactericidal/permeability increasing protein to target bacteria. Implications and use as a means of purification
29. Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14
30. Lipopolysaccharide (LPS) binding protein, truncated at Ile-197, binds LPS but does not transfer LPS to CD14
31. Purification and characterization of an endotoxin-binding protein with protease inhibitory activity from Limulus amebocytes
32. Affinities of different proteins and peptides for lipopolysaccharide as determined by biosensor technology
33. Binding of polymyxin B nonapeptide to gram-negative bacteria
34. Interaction between lipopolysaccharide and intracellular serine protease zymogen, Factor C, from horseshoe crab (Tachypleus tridentatus) hemocytes