Crystal structure and catalytic mechanism of the LPS 3-O-deacylase PagL from Pseudomonas aeruginosa

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 18, 2006, Pages 7071-7076

  Rutten, Lucy ^a   Geurtsen, Jeroen ^b,c   Lambert, Wietske ^a   Smolenaers, Jeroen J M ^a   Bonvin, Alexandre M ^a   De Haan, Alex ^c   Van Der Ley, Peter ^c   Egmond, Maarten R ^a   Gros, Piet ^a   Tommassen, Jan ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c NETHERLANDS VACCINE INSTITUTE   (Netherlands)

Author keywords

Lipopolysaccharide; Outer membrane protein; Serine hydrolase

Indexed keywords

ASPARAGINE; GLUTAMIC ACID; HISTIDINE; LIPID A; LIPID X; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE 3 O DEACYLASE; PHENYLALANINE; PHOSPHOLIPASE A; PROTEIN PAGL; SERINE; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; GRAM NEGATIVE BACTERIUM; IMMUNE RESPONSE; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA;

BACTERIAL OUTER MEMBRANE PROTEINS; BINDING SITES; CARBOXYLIC ESTER HYDROLASES; CRYSTALLOGRAPHY, X-RAY; LIPID A; LIPOPOLYSACCHARIDES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA; RECOMBINANT PROTEINS;

NEGIBACTERIA; PSEUDOMONAS AERUGINOSA;

EID: 33646490988     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0509392103     Document Type: Article

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