Dissemination of lipid A deacylases (PagL) among gram-negative bacteria: Identification of active-site histidine and serine residues

Journal of Biological Chemistry

Volumn 280, Issue 9, 2005, Pages 8248-8259

  Geurtsen, Jeroen ^a,b   Steeghs, Liana ^c   Hove, Jan Ten ^d   Van Der Ley, Peter ^b   Tommassen, Jan ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b NETHERLANDS VACCINE INSTITUTE   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOCHEMISTRY; BIOLOGICAL MEMBRANES; CATALYSIS; ENZYMES; GENES; LIPIDS; OLIGOMERS; POLYSACCHARIDES; YEAST;

DEACYLATION; GRAM-NEGATIVE BACTERIA; LIPOPOLYSACCHARIDES (LPS); PATHOGENECITY;

ENZYME KINETICS;

AMIDASE; BACTERIAL ENZYME; HISTIDINE; LIPID A; LIPID A DEACYLASE; O ANTIGEN; OLIGOSACCHARIDE; SERINE; SERINE DEHYDRATASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; BORDETELLA BRONCHISEPTICA; CARBOXY TERMINAL SEQUENCE; CATALYSIS; DEACYLATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; NONHUMAN; NUCLEOTIDE SEQUENCE; PAGL GENE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PSEUDOMONAS AERUGINOSA; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANTIBODIES; BACTERIAL PROTEINS; BINDING SITES; BORDETELLA BRONCHISEPTICA; CARBOHYDRATE SEQUENCE; CARBOXYLIC ESTER HYDROLASES; CENTRIFUGATION; CLONING, MOLECULAR; DISACCHARIDES; DNA; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLYCINE; HISTIDINE; IMMUNOBLOTTING; LIPID A; LIPIDS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PLASMIDS; PSEUDOMONAS AERUGINOSA; SALMONELLA ENTERICA; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 14844316639     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M414235200     Document Type: Article

References (49)

1. Raetz, C. R. H., and Whitfield, C. (2002) Annu. Rev. Biochem. 71, 635-700
2. Loppnow, H., Brade, H., Durrbaum, I., Dinarello, C. A., Kusumoto, S., Rietschel, E. T., and Flad, H. D. (1989) J. Immunol. 142, 3229-3238
3. Steeghs, L., Berns, M., ten Hove, J., de Jong, A., Roholl, P., van Alphen, L., Tommassen, J., and van der Ley, P. (2002) Cell. Microbiol. 4, 599-611
4. Nikaido, H., and Vaara, M. (1987) in Escherichia coli and Salmonella: Cellular and Molecular Biology (Neidhardt, F. C., ed) Vol. 1, pp. 7-22, American Society for Microbiology, Washington, D. C.
5. Caroff, M., Karibian, D., Cavaillon, J.-M., and Haeffner-Cavaillon, N. (2002) Microbes Infect. 4, 915-926
6. Guo, L., Lim, K. B., Gunn, J. S., Bainbridge, B., Darveau, R. P., Hackett, M., and Miller, S. I. (1997) Science 276, 250-253
7. Guo, L., Lim, K. B., Poduje, C. M., Daniel, M., Gunn, J. S., Hackett, M., and Miller, S. I. (1998) Cell 95, 189-198
8. Gunn, J. S., Belden, W. J., and Miller, S. I. (1998) Microb. Pathog. 25, 77-90
9. Gunn, J. S., Lim, K. B., Krueger, J., Kim, K., Guo, L., Hackett, M., and Miller, S. I. (1998) Mol. Microbiol. 27, 1171-1182
10. Gunn, J. S., Ryan, S. S., Van Velkinburgh, J. C., Ernst, R. K., and Miller, S. I. (2000) Infect. Immun. 68, 6139-6146
11. Miller, S. I., Kukral, A. M., and Mekalanos, J. J. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 5054-5058
12. Gunn, J. S., and Miller, S. I. (1996) J. Bacteriol. 178, 6857-6864
13. Ernst, R. K., Guina, T., and Miller, S. I. (1999) J. Infect. Dis. 179, (Suppl. 2) 326-330
14. Ernst, R. K., Yi, E. C., Guo, L., Lim, K. B., Burns, J. L., Hackett, M., and Miller, S. I. (1999) Science 286, 1561-1565
15. Trent, M. S., Ribeiro, A. A., Lin, S., Cotter, R. J., and Raetz, C. R. H. (2001) J. Biol. Chem. 276, 43122-43131
16. Lee, H., Hsu, F. F., Turk, J., and Groisman, E. A. (2004) J. Bacteriol. 186, 4124-4133
17. Gibbons, H. S., Lin, S., Cotter, R. J., and Raetz, C. R. H. (2000) J. Biol. Chem. 275, 32940-32949
18. Karbarz, M. J., Kalb, S. R., Cotter, R. J., and Raetz, C. R. H. (2003) J. Biol. Chem. 278, 39269-39279
19. Bishop, R. E., Gibbons, H. S., Guina, T., Trent, M. S., Miller, S. I., and Raetz, C. R. H. (2000) EMBO J. 19, 5071-5080
20. Tanamoto, K., and Azumi, S. (2000) J. Immunol. 164, 3149-3156
21. Robey, M., O'Connell, W., and Cianciotto, N. P. (2001) Infect. Immun. 69, 4276-4286
22. Trent, M. S., Pabich, W., Raetz, C. R. H., and Miller, S. I. (2001) J. Biol. Chem. 276, 9083-9092
23. Bhat, U. R., Forsberg, L. S., and Carlson, R. W. (1994) J. Biol. Chem. 269, 14402-14410
24. Moran, A. P., Lindner, B., and Walsh, E. J. (1997) J. Bacteriol. 179, 6453-6463
25. Kumada, H., Haishima, Y., Umemoto, T., and Tanamoto, K. (1995) J. Bacteriol. 177, 2098-2106
26. Tommassen, J., van Tol, H., and Lugtenberg, B. (1983) EMBO J. 2, 1275-1279
27. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) in Molecular Cloning: A Laboratory Manual, 2nd Ed., pp. 1.82-1.84, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
28. Laemmli, U. K. (1970) Nature 227, 680-685
29. Dekker, N., Merck, K., Tommassen, J., and Verheij, H. M. (1995) Eur. J. Biochem. 232, 214-219
30. Lesse, A. J., Campagnari, A. A., Bittner, W. E., and Apicella, M. A. (1990) J. Immunol. Methods 126, 109-117
31. Tsai, C. M., and Frasch, C. E. (1982) Anal. Biochem. 119, 115-119
32. Westphal, O., and Jann, J. K. (1965) Methods Carbohydr. Chem. 5, 83-91
33. Wilm, M., and Mann, M. (1996) Anal. Chem. 68, 1-8
34. Altschul, S. F., Gish, W., Miller, W., Myers, E. W., and Lipman, D. J. (1990) J. Mol. Biol. 215, 403-410
35. Nielsen, H., Brunak, S., and von Heijne, G. (1999) Protein Eng. 12, 3-9
36. Parkhill, J., Sebaihia, M., Preston, A., Murphy, L. D., Thomson, N., Harris, D. E., Holden, M. T., Churcher, C. M., Bentley, S. D., Mungall, K. L., Cerdeno-Tarraga, A. M., Temple, L., James, K., Harris, B., Quail, M. A., Achtman, M., Atkin, R., Baker, S., Basham, D., Bason, N., Cherevach, I., Chillingworth, T., Collins, M., Cronin, A., Davis, P., Doggett, J., Feltwell, T., Goble, A., Hamlin, N., Hauser, H., Holroyd, S., Jagels, K., Leather, S., Moule, S., Norberczak, H., O'Neil, S., Ormond, D., Price, C., Rabbinowitsch, E., Rutter, S., Sanders, M., Saunders, D., Seeger, K., Sharp, S., Simmonds, M., Skelton, J., Squares, R., Squares, S., Stevens, K., Unwin, L., Whitehead, S., Barrell, B. G., and Maskell, D. J. (2003) Nat. Genet. 35, 32-40
37. Snijder, H. J., Ubarretxena-Belandia, I., Blaauw, M., Kalk, K. H., Verheij, H. M., Egmond, M. R., Dekker, N., and Dijkstra, B. W. (1999) Nature 401, 717-721
38. McClelland, M., Sanderson, K. E., Spieth, J., Clifton, S. W., Latreille, P., Courtney, L., Porwollik, S., Ali, J., Dante, M., Du, F., Hou, S., Layman, D., Leonard, S., Nguyen, C., Scott, K., Holmes, A., Grewal, N., Mulvaney, E., Ryan, E., Sun, H., Florea, L., Miller, W., Stoneking, T., Nhan, M., Waterston, R., and Wilson, R. K. (2001) Nature 413, 852-856
39. Basu, S. S., White, K. A., Que, N. L., and Raetz, C. R. H. (1999) J. Biol. Chem. 274, 11150-11158
40. Kulshin, V. A., Zahringer, U., Lindner, B., Jager, K. E., Dmitriev, B. A., and Rietschel, E. T. (1991) Eur. J. Biochem. 198, 697-704
41. Hwang, P. M., Choy, W. Y., Lo, E. I., Chen, L., Forman-Kay, J. D., Raetz, C. R., Prive, G. G., Bishop, R. E., and Kay, L. E. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 13560-13565
42. Kol, M. A., van Dalen, A., de Kroon, A. I., and de Kruijff, B. (2003) J. Biol. Chem. 278, 24586-24593
43. von Heijne, G. (1983) Eur. J. Biochem. 133, 17-21
44. Tommassen, J. (1988) in Membrane Biogenesis (Op den Kamp, J. A. F., ed) NATO ASI series, Vol. H16, pp. 351-373. Springer Verlag, Berlin
45. Jacobs, M. A., Alwood, A., Thaipisuttikul, I., Spencer, D., Haugen, E., Ernst, S., Will, O., Kaul, R., Raymond, C., Levy, R., Chun-Rong, L., Guenthner, D., Bovee, D., Olson, M. V., and Manoil, C. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 14339-14344
46. Haas, D., and Holloway, B. W. (1976) Mol. Gen. Genet. 144, 243-251
47. Pace, J., Hayman, M. J., and Galan, J. E. (1993) Cell 72, 505-514
48. Hanahan, D. (1983) J. Mol. Biol. 166, 557-580
49. Winkler, K. C., and de Haan, P. G. (1948) Arch. Biochem. 18, 97-107