Decoupling of normal CD40/interleukin-4 immunoglobulin heavy chain switch signal leads to genomic instability in SGH-MM5 and RPMI 8226 multiple myeloma cell lines

Leukemia

Volumn 20, Issue 4, 2006, Pages 715-723

  Hwang, W Y K ^a,b   Gullo, C A ^a,c   Shen, J ^a,c   Poh, C K ^a,b   Tham, S C ^a,c   Cow, G ^a   Au, M ^a,c   Chan, E W E ^d   Teoh, G ^a,b,d  

^a Singapore Health Services   (Singapore)

^b SINGAPORE GENERAL HOSPITAL   (Singapore)

^c SGH   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Activation induced cytidine deaminase; DNA double stand breaks; DNA protein kinase; DNA repair; Ku proteins

Indexed keywords

CD40 ANTIGEN; CYTIDINE DEAMINASE; DOUBLE STRANDED RNA; IMMUNOGLOBULIN HEAVY CHAIN; INTERLEUKIN 4;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELL GROWTH; CONTROLLED STUDY; GENE REARRANGEMENT; GENE SWITCHING; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; KARYOTYPING; MOLECULAR CLONING; MULTIPLE MYELOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

EID: 33646488658     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404099     Document Type: Article

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