Subtoxic concentrations of allergenic haptens induce LC migration and maturation in a human organotypic skin explant culture model: A novel method for identifying potential contact allergens

Experimental Dermatology

Volumn 15, Issue 6, 2006, Pages 421-431

  Lehé, Cynthia L ^a   Jacobs, John J L ^a,b,c   Hua, Chi Mei ^a   Courtellemont, P ^d   Elliott, Graham R ^b,e   Das, Pranab K ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b TNO   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

^d Parfums Christian Dior   (France)

^e Derphartox   (Netherlands)

Author keywords

Activation markers; Allergen; HOSEC; Langerhans cell; Migration

Indexed keywords

CD83 ANTIGEN; CONTACT ALLERGEN; HAPTEN; HLA DR ANTIGEN; IRRITANT AGENT; T6 ANTIGEN;

ALLERGENICITY; ANTIGEN EXPRESSION; ARTICLE; CELL MATURATION; CELL MIGRATION; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; EPIDERMIS; EPIDERMIS CELL; EXPLANT; FLOW CYTOMETRY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LANGERHANS CELL; QUANTITATIVE ANALYSIS; SKIN BIOPSY; SKIN CULTURE; UPREGULATION;

ALLERGENS; ANTIGENS, CD; CELL DIFFERENTIATION; CELL MOVEMENT; DERMATITIS, ALLERGIC CONTACT; HAPTENS; HUMANS; IMMUNOGLOBULINS; LANGERHANS CELLS; MEMBRANE GLYCOPROTEINS; MODELS, BIOLOGICAL; SKIN; TISSUE CULTURE TECHNIQUES;

EID: 33646473016     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.0906-6705.2006.00415.x     Document Type: Article

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