An in vitro model for detecting skin irritants: Methyl green-pyronine staining of human skin explant cultures

Toxicology in Vitro

Volumn 16, Issue 5, 2002, Pages 581-588

  Jacobs, J J L ^a,b,c   Lehe C ^b   Cammans, K D A ^a   Das, P K ^b   Elliott, G R ^a  

^a TNO   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Alternative method; Human skin; Irritant testing; Methyl green pyronine; Pig skin

Indexed keywords

IRRITANT AGENT; METHYL GREEN; PYRONINE;

ANIMAL TISSUE; ARTICLE; CLASSIFICATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; EXPLANT; HAZARD ASSESSMENT; HUMAN; HUMAN TISSUE; IN VITRO STUDY; KERATINOCYTE; NONHUMAN; PREDICTION; RISK ASSESSMENT; SCORING SYSTEM; SKIN IRRITATION; SWINE; TOXICITY TESTING;

ANIMAL TESTING ALTERNATIVES; ANIMALS; CELLS, CULTURED; COLORING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IRRITANTS; METHYL GREEN; PYRONINE; RABBITS; REPRODUCIBILITY OF RESULTS; RNA; SKIN; STAINING AND LABELING; SWINE; TOXICITY TESTS;

ORYCTOLAGUS CUNICULUS; SUIDAE; SUS SCROFA;

EID: 0036773245     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(02)00039-5     Document Type: Article

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