Irritant threshold and histological response of epidermis to irritant application

Contact Dermatitis

Volumn 51, Issue 5-6, 2004, Pages 227-230

  Smith, H R ^a,c   Orchard, G E ^a   Calonje, E ^a   Basketter, D A ^b   McFadden, J P ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b UNILEVER RESEARCH   (United Kingdom)

^c ROYAL HOSPITAL HASLAR   (United Kingdom)

Author keywords

Epidermis; Irritant threshold; Keratinocyte; Sodium lauryl sulfate

Indexed keywords

CYTOKINE; DODECYL SULFATE SODIUM; EOSIN; HEMATOXYLIN; IRRITANT AGENT; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ERYTHEMA; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LANGERHANS CELL; SKIN BIOPSY; SKIN IRRITATION; TOXICITY TESTING;

ANTIGENS, CD1; BIOPSY; CELL NUCLEUS; COLORING AGENTS; CYTOPLASM; EOSINE YELLOWISH-(YS); FLUORESCENT DYES; HEMATOXYLIN; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION MEDIATORS; IRRITANTS; LANGERHANS CELLS; SKIN; SODIUM DODECYL SULFATE; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 11144291500     PISSN: 01051873     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0105-1873.2004.00388.x     Document Type: Article

References (18)

1. Judge M R, Griffiths H A, Basketter D A et al. Variation in response of human skin to irritant challenge. Contact Dermatitis 1996: 34: 115-117.
2. Basketer D. Contact irritation models. In: Toxicology of Contact Dermatitis, Basketer D, Gerbrick F, Kimber I, Willis C (eds): Chichester, John Wiley & Sons, 1999: 39-56.
3. Willis C M, Stephens C J M, Wilkinson J D. Epidermal damage induced by irritants in man: a light and electron microscopic study. J Invest Dermatol 1989: 93: 695-699.
4. Lindberg M, Färm G, Scheynius A. Differential effects of sodium lauryl sulphate and nonanoic acid on the expression of CD1a and ICAM-1 in human epidermis. Acta Derm Venereol (Stockh) 1991: 71: 384-388.
5. Lisby S, Baadsgaard O, Cooper K D, Vejlsgaard G L. Decreased number and function of antigen-presenting cells in the skin following application of irritant agents: relevance for skin cancer? J Invest Dermatol 1989: 92: 842-847.
6. Ferguson J, Gibbs J H, Beck J S. Lymphocyte subsets and Langerhans cells in allergic and irritant patch test reactions: histometric studies. Contact Dermatitis 1985: 13: 166-174.
7. Mikulowska A, Andersson A. Sodium lauryl sulphate effect on the density of epidermal Langerhans cells. Evaluation of different test models. Contact Dermatitis 1996: 34: 397-401.
8. Brand C U, Hunziker T, Limat A, Braathen L R. Large increase of Langerhans cells in human skin lymph derived from irritant contact dermatitis. Br J Dermatol 1993: 128: 184-188.
9. Cumberbatch M, Dearman R J, Griffiths C E M et al. Langerhans cell migration. Clin Exp Dermatol 2000: 25: 413-418.
10. Conti A, Di Nardo A, Seidenari S. No alteration of biophysical parameters in the skin of subjects with respiratory atopy. Dermatology 1996: 192(4): 317-320.
11. Bieber T, Ring J, Braun-Falco O. Comparison of different methods for enumeration of Langerhans cells in vertical cryosections of human skin. Br J Dermatol 1988: 118: 385-392.
12. Allen M H, Wakelin S H, Holloway D et al. Association of TNFA gene polymorphism at position -308 with susceptibility to irritant contact dermatitis. Immunogenetics 2000: 51: 201-205.
13. Barker J N W N, Mitra R S, Griffiths C E M et al. Keratinocytes as initiators of inflammation. Lancet 1991: 337: 211-214.
14. Wilmer J L, Burleson F G, Kayama F et al. Cytokine induction in human epidermal keratinocytes exposed to contact irritants and its relation to chemical-induced inflammation in mouse skin. J Invest Dermatol 1994: 102: 915-922.
15. Kock A, Schwarz T, Kirnbauer R et al. Human keratinocytes are a source for tumour necrosis factor α: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light. J Exp Med 1990: 172: 1609-1614.
16. Hunziker T, Brand C U, Kapp A et al. Increased levels of inflammatory cytokines in human skin lymph derived from sodium lauryl sulphate-induced contact dermatitis. Br J Dermatol 1992: 127: 254-257.
17. Nickoloff B J, Naidu Y. Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin. J Am Acad Dermatol 1994: 30: 535-546.
18. Brand C U, Braathen L R. Investigation of skin-derived lymph: an approach to get insight into the skin immune system. Dermatology 1996: 193: 283-288.