Surfactant as an airway smooth muscle relaxant

American Journal of Respiratory Cell and Molecular Biology

Volumn 34, Issue 5, 2006, Pages 609-615

  Koetzler, Rommy ^a   Saifeddine, Mahmoud ^a   Yu, Zhenguo ^a   Schürch, F Samuel ^a   Hollenberg, Morley D ^a   Green, Francis H Y ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Asthma; Nitric oxide; Prostaglandins; Smooth muscle; Surfactant

Indexed keywords

ALBUMIN; BERACTANT; CHOLESTEROL; DIPALMITOYLPHOSPHATIDYLCHOLINE; INDOMETACIN; ISOPRENALINE; LUNG SURFACTANT; LUNG SURFACTANT EXTRACT; LYSOPHOSPHATIDYLCHOLINE; METHACHOLINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLGLYCEROL; PHOSPHOLIPID; PROSTAGLANDIN SYNTHASE; PROSTANOID; SUBSTANCE P; SURFACTANT ASSOCIATED PROTEIN; SURFACTANT PROTEIN A; SURFACTANT PROTEIN D;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; BIOASSAY; BRONCHOSPASM; BRONCHUS MUSCLE; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; MALE; NONHUMAN; RAT; RESPIRATORY EPITHELIUM; SMOOTH MUSCLE RELAXATION; SMOOTH MUSCLE TONE;

ANIMALS; BRONCHI; CATTLE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; LIPIDS; MALE; MUSCLE RELAXATION; MUSCLE, SMOOTH; PROTEINS; PULMONARY SURFACTANTS; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY MUCOSA; RESPIRATORY SYSTEM;

ANIMALIA; BOVINAE;

EID: 33646456741     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2005-0228OC     Document Type: Article

References (45)

1. Griese M. Pulmonary surfactant in health and human lung diseases: state of the art. Eur Respir J 1999;13:1455-1476.
2. Bernhard W, Haagsman HP, Tschernig T, Poets CF, Postle AD, van Eijk ME, von der Hardt H. Conductive airway surfactant: surface-tension function, biochemical composition, and possible alveolar origin. Am J Respir Cell Mol Biol 1997;17:41-50.
3. Orgeig S, Daniels CB, Johnston SD, Sullivan LC. The pattern of surfactant cholesterol during vertebrate evolution and development: does ontogeny recapitulate phylogeny? Reprod Fertil Dev 2003;15:55-73.
4. Creuwels LA, van Golde LM, Haagsman HP. The pulmonary surfactant system: biochemical and clinical aspects. Lung 1997;175:1-39.
5. Geiser M, Schürch S, Gehr P. Influence of surface chemistry and topography of particles on their immersion into the lung's surface-lining layer. J Appl Physiol 2003;94:1793-1801.
6. Wright JR. Immunomodulatory functions of surfactant. Physiol Rev 1997;77:931-962.
7. Hohlfeld JM. The role of surfactant in asthma. Respir Res 2002;3:4.
8. Gehr P, Green FH, Geiser M, Im Hof V, Lee MM, Schürch S. Airway surfactant, a primary defense barrier: mechanical and immunological aspects. J Aerosol Med 1996;9:163-181.
9. Baritussio A. Lung surfactant, asthma and allergens. Am J Respir Crit Care Med 2004;169:550-551.
10. Wright SM, Hockey PM, Enhorning G, Strong P, Reid KB, Holgate ST, Djukanovic R, Postle AD. Altered airway surfactant phospholipid composition and reduced lung function in asthma. J Appl Physiol 2000;89:1283-1292.
11. Haczku A, Atochina EN, Tomer Y, Cao Y, Campbell C, Scanlon ST, Russo SJ, Enhorning G, Beers MF. The late asthmatic response is linked with increased surface tension and reduced surfactant protein B in mice. Am J Physiol Lung Cell Mol Physiol 2002;283:L755-L765.
12. Cheng G, Ueda T, Sugiyama K, Toda M, Fukuda T. Compositional and functional changes of pulmonary surfactant in a guinea-pig model of chronic asthma. Respir Med 2001;95:180-186.
13. Lee MM, Green FH, Schürch S, Cheng S, Bjarnason SG, Leonard S, Wallace W, Possmayer F, Vallyathan V. Comparison of inhibitory effects of oxygen radicals and calf serum protein on surfactant activity. Mol Cell Biochem 2004;259:15-22.
14. Hohlfeld JM, Schmiedl A, Erpenbeck VJ, Venge P, Krug N. Eosinophil cationic protein alters pulmonary surfactant structure and function in asthma. J Allergy Clin Immunol 2004;113:496-502.
15. Nobata K, Kurashima K, Fujimura M, Abo M, Ishiura Y, Kasahara K, Nakao S. Inhaled lysophosphatidylcholine provokes bronchoconstriction in guinea pigs in vivo. Eur J Pharmacol 2005;520:150-155.
16. Liu M, Wang L, Li E, Enhorning G. Pulmonary surfactant given prophylactically alleviates an asthma attack in guinea-pigs. Clin Exp Allergy 1996;26:270-275.
17. Babu KS, Woodcock DA, Smith SE, Staniford JN, Holgate ST, Conway JH. Inhaled synthetic surfactant abolishes the early allergen-induced response in asthma. Eur Respir J 2003;153:1148-1152.
18. Kurashima K, Ogawa H, Ohka T. A pilot study of surfactant inhalation for the treatment of asthmatic attack. Arerugi 1991;40:160-163.
19. Erpenbeck VJ, Hagenberg A, Dulkys Y, Elsner J, Balder R, Krentel H, Discher M, Braun A, Krug N, Hohlfeld JM. Natural porcine surfactant augments airway inflammation after allergen challenge in patients with asthma. Am J Respir Crit Care Med 2004;169:578-586.
20. Puligandla PS, Gill T, McCaig LA, Yao LJ, Veldhuizen RA, Possmayer F, Lewis JF. Alveolar environment influences the metabolic and physical properties of exogenous surfactants. J Appl Physiol 2000;88:1061-1071.
21. Bartlett GR. Phosphorus assay in column chromatography. J Biol Chem 1959;234:466-468.
22. Saifeddine M, Al-Ani B, Sandhu S, Wijesuriya SJ, Hollenberg MD. Contractile actions of proteinase-activated receptor-derived polypeptides in guinea-pig gastric and lung parenchymal strips: evidence for distinct receptor systems. Br J Pharmacol 2001;132:556-566.
23. Uhlig S, Nusing R, von Bethmann A, Featherstone RL, Klein T, Brasch F, Muller KM, Ullrich V, Wendel A. Cyclooxygenase-2-dependent bronchoconstriction in perfused rat lungs exposed to endotoxin. Mol Med 1996;2:373-383.
24. Zheng XL, Gui Y, Sharkey KA, Hollenberg MD. Differential induction of nitric oxide synthase in rat gastric and vascular smooth muscle tissue: distinct tissue distribution and distinctive signaling pathways. J Pharmacol Exp Ther 1999;289:632-640.
25. Wagner EM, Jacoby DB. Methacholine causes reflex bronchoconstriction. J Appl Physiol 1999;86:294-297.
26. Hohlfeld J, Hoymann HG, Molthan J, Fabel H, Heinrich U. Aerosolized surfactant inhibits acetylcholine-induced airway obstruction in rats. Eur Respir J 1997;10:2198-2203.
27. Hills BA, Chen Y, Hills YC. Adsorption of surfactant to bronchial epithelium: possible role of receptor 'unmasking' in asthma. J Asthma 2003;40:445-450.
28. Gunasekara L, Schüren S, Schoel WM, Nag K, Leonenko Z, Hauts M, Amrein M. Pulmonary surfactant function is abolished by an elevated proportion of cholesterol. Biochim Biophys Acta 2005;1737:27-35.
29. Bernhard W, Mottaghian J, Gebert A, Rau GA, von der Hardt H, Poets CF. Commercial versus native surfactants. Am J Respir Crit Care Med 2000;162:1524-1533.
30. Palmer D, Schürch S, Belik J. Effect of budesonide and salbutamol on surfactant properties. J Appl Physiol 2000;89:884-890.
31. Yu SH, Chung W, Possmayer F. Structural relationship between the two small hydrophobic apoproteins in bovine pulmonary surfactant. Biochim Biophys Acta 1989;1005:93-96.
32. 2. Am J Physiol Lung Cell Mol Physiol 2001;281:L469-L474.
33. Brindley DN, Waggoner DW. Phosphatidate phosphohydrolase and signal transduction. Chem Phys Lipids 1996;80:45-57.
34. Luo SF, Wang CC, Chien CS, Hsiao LD, Yang CM. Induction of cyclooxygenase-2 by lipopolysaccharide in canine tracheal smooth muscle cells: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kappaB pathways. Cell Signal 2003;15:497-509.
35. Riento K, Ridley AJ. Rocks: multifunctional kinases in cell behaviour. Nat Rev Mol Cell Biol 2003;4:446-456.
36. Auten RL, Watkins RH, Shapiro DL, Horowitz S. Surfactant apoprotein A (SP-A) is synthesized in airway cells. Am J Respir Cell Mol Biol 1990;3:491-496.
37. Mehta D, Gupta S, Gaur SN, Gangal SV, Agrawal KP. Increased leukocyte phospholipase A2 activity and plasma lysophosphatidylcholine levels in asthma and rhinitis and their relationship to airway sensitivity to histamine. Am Rev Respir Dis 1990;142:157-161.
38. Holm BA, Wang Z, Notter RH. Multiple mechanisms of lung surfactant inhibition. Pediatr Res 1999;46:85-93.
39. Tino MJ, Wright JR. Interactions of surfactant protein A with epithelial cells and phagocytes. Biochim Biophys Acta 1998;1408:241-263.
40. Wang JY, Shieh CC, Yu CK, Lei HY. Allergen-induced bronchial inflammation is associated with decreased levels of surfactant proteins A and D in a murine model of asthma. Clin Exp Allergy 2001;31:652-662.
41. van de Graaf EA, Jansen HM, Lutter R, Alberts C, Kobesen J, de Vries IJ, Out TA. Surfactant protein A in bronchoalveolar lavage fluid. J Lab Clin Med 1992;120:252-263.
42. McCormack FX, Whitsett JA. The pulmonary collectins, SP-A and SP-D, orchestrate innate immunity in the lung. J Clin Invest 2002;109:707-712.
43. 2 regulation of arachidonic acid mobilization. FEBS Lett 2002;531:2-6.
44. Nanjundan M, Possmayer F. Pulmonary phosphatidic acid phosphatase and lipid phosphate phosphohydrolase. Am J Physiol Lung Cell Mol Physiol 2003;264:L1-L23.
45. Becher G. Lung surfactant prevents allergic bronchial constriction in ovalbumin sensitized guinea pigs. Biomed Biochim Acta 1985;44:K57-K61.