Nitric oxide attenuates IGF-I-induced aortic smooth muscle cell motility by decreasing Rac1 activity: Essential role of PTP-PEST and p130cas

American Journal of Physiology - Cell Physiology

Volumn 290, Issue 4, 2006, Pages

  Ceacareanu, Alice Corina ^a   Ceacareanu, Bogdan ^a   Zhuang, Daming ^a   Chang, Yingzi ^a   Ray, Ramesh M ^a   Desai, Leena ^a   Chapman, Kenneth E ^a   Waters, Christopher M ^a   Hassid, Aviv ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Hydrogen peroxide; p130cas; Protein tyrosine phosphatase proline, glutamate, serine, and threonine sequence protein

Indexed keywords

1 [2 (2 AMINOETHYL) N (2 AMMONIOETHYL)AMINO]DIAZEN 1 IUM 1,2 DIOLATE; GUANOSINE TRIPHOSPHATASE; HYDROGEN PEROXIDE; NITRIC OXIDE; NITRIC OXIDE DONOR; PROTEIN P130; PROTEIN TYROSINE PHOSPHATASE; RAC1 PROTEIN; SOMATOMEDIN C; TYROSINE PHOSPHATASE PROLYLGLUTAMYLSERYLTHREONINE SEQUENCE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; AORTA MEDIA; ARTICLE; CELL MOTILITY; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER;

ANIMALS; AORTA; CELL MOVEMENT; CRK-ASSOCIATED SUBSTRATE PROTEIN; ENZYME ACTIVATION; FEMALE; HYDROGEN PEROXIDE; INSULIN-LIKE GROWTH FACTOR I; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NITRIC OXIDE; NITRIC OXIDE DONORS; OXIDANTS; PHOSPHOTYROSINE; PROTEIN-TYROSINE-PHOSPHATASE; RAC1 GTP-BINDING PROTEIN; RATS; RATS, SPRAGUE-DAWLEY; TRIAZENES;

ANIMALIA;

EID: 33646413397     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00241.2005     Document Type: Article

References (44)

1. Albertinazzi C, Cattelino A, and de Curtis I. Rac GTPases localize at sites of actin reorganization during dynamic remodeling of the cytoskeleton of normal embryonic fibroblasts. J Cell Sci 112: 3821-3831, 1999.
2. Anderson RD, Haskell RE, Xia H, Roessler BJ, and Davidson BL. A simple method for the rapid generation of recombinant adenovirus vectors. Gene Ther 7: 1034-1038, 2000.
3. Bengtsson SH, Gulluyan LM, Dusting GJ, and Drummond GR. Novel isoforms of NADPH oxidase in vascular physiology and pathophysiology. Clin Exp Pharmacol Physiol 30: 849-854, 2003.
4. Chang Y, Ceacareanu B, Dixit M, Sreejayan N, and Hassid A. Nitric oxide-induced motility in aortic smooth muscle cells: role of protein tyrosine phosphatase SHP-2 and GTP-binding protein Rho. Circ Res 91: 390-397, 2002.
5. Clancy RM, Leszczynska-Piziak J, and Abramson SB. Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase. J Clin Invest 90: 1116-1121, 1992.
6. Clerk A, Pham FH, Fuller SJ, Sahai E, Aktories K, Marais R, Marshall C, and Sugden PH. Regulation of mitogen-activated protein kinases in cardiac myocytes through the small G protein Rac1. Mol Cell Biol 21: 1173-1184, 2001.
7. Delafontaine P and Ku L. Reactive oxygen species stimulate insulin-like growth factor I synthesis in vascular smooth muscle cells. Cardiovasc Res 33: 216-222, 1997.
8. De Meyer GR, Bult H, Üstünes L, Kockx MM, Feelisch M, and Herman AG. Effect of nitric oxide donors on neointima formation and vascular reactivity in the collared carotid artery of rabbits. J Cardiovasc Pharmacol 26: 272-279, 1995.
9. Doanes AM, Irani K, Goldschmidt-Clermont PJ, and Finkel T. A requirement for rac1 in the PDGF-stimulated migration of fibroblasts and vascular smooth cells. Biochem Mol Biol Int 45: 279-287, 1998.
10. Fujii H, Ichimori K, Hoshiai K, and Nakazawa H. Nitric oxide inactivates NADPH oxidase in pig neutrophils by inhibiting its assembling process. J Biol Chem 272: 32773-32778, 1997.
11. Garg UC and Hassid A. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest 83: 1774-1777, 1989.
12. Griendling KK, Sorescu D, and Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 86: 494-501, 2000.
13. Guzik TJ, West NE, Pillai R, Taggart DP, and Channon KM. Nitric oxide modulates superoxide release and peroxynitrite formation in human blood vessels. Hypertension 39: 1088-1094, 2002.
14. Hassid A, Yao J, and Huang S. NO alters cell shape and motility in aortic smooth muscle cells via protein tyrosine phosphatase 1B activation. Am J Physiol Heart Circ Physiol 277: H1014-H1026, 1999.
15. Heyworth PG, Knaus UG, Xu X, Uhlinger DJ, Conroy L, Bokoch GM, and Curnutte JT. Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase. Mol Biol Cell 4: 261-269, 1993.
16. Hultgårdh-Nilsson A, Krondahl U, Jiang WQ, Nilsson J, and Ringertz NR. Endogenous activation of c-myc expression and DNA synthesis in serum-starved neonatal rat smooth muscle cells. Differentiation 52: 161-168, 1993.
17. Janssens S, Flaherty D, Nong Z, Varenne O, van Pelt N, Haustermans C, Zoldhelyi P, Gerard R, and Collen D. Human endothelial nitric oxide synthase gene transfer inhibits vascular smooth muscle cell proliferation and neointima formation after balloon injury in rats. Circulation 97: 1274-1281, 1998.
18. Khorsandi MJ, Fagin JA, Giannella-Neto D, Forrester JS, and Cercek B. Regulation of insulin-like growth factor-I and its receptor in rat aorta after balloon denudation: evidence for local bioactivity. J Clin Invest 90: 1926-1931, 1992.
19. Cas tyrosine phosphorylated substrate domain decoy disrupts v-Crk signaling. BMC Cell Biol 3: 18, 2002.
20. Klemke RL, Leng J, Molander R, Brooks PC, Vuori K, and Cheresh DA. CAS/Crk coupling serves as a "molecular switch" for induction of cell migration. J Cell Biol 140: 961-972, 1998.
21. Li H, Dimayuga P, Yamashita M, Yano J, Fournier M, Lewis M, and Cercek B. Arterial injury in mice with severe insulin-like growth factor-1 (IGF-1) deficiency. J Cardiovasc Pharmacol Ther 7: 227-233, 2002.
22. cas and Crk. Am J Physiol Heart Circ Physiol 285: H710-H721, 2003.
23. Nickenig G and Harrison DG. The AT1-type angiotensin receptor in oxidative stress and atherogenesis. Part I: oxidative stress and atherogenesis. Circulation 105: 393-396, 2002.
24. Offermann MK and Medford RM. Antioxidants and atherosclerosis: a molecular perspective. Heart Dis Stroke 3: 52-57, 1994.
25. Olson MF, Ashworth A, and Hall A. An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1. Science 269: 1270-1272, 1995.
26. Patil S, Bunderson M, Wilham J, and Black SM. Important role for Rac1 in regulating reactive oxygen species generation and pulmonary arterial smooth muscle cell growth. Am J Physiol Lung Cell Mol Physiol 287: L1314-L1322, 2004.
27. Ross R. Cell biology of atherosclerosis. Annu Rev Physiol 57: 791-804, 1995.
28. Rubanyi GM, Ho EH, Cantor EH, Lumma WC, and Botelho LH. Cytoprotective function of nitric oxide: inactivation of superoxide radicals produced by human leukocytes. Biochem Biophys Res Commun 181: 1392-1397, 1991.
29. Rudic RD, Shesely EG, Maeda N, Smithies O, Segal SS, and Sessa WC. Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling. J Clin Invest 101: 731-736, 1998.
30. Sastry SK, Lyons PD, Schaller MD, and Burridge K. PTP-PEST controls motility through regulation of Rac1. J Cell Sci 115: 4305-4316, 2002.
31. Seshiah PN, Weber DS, Rocic P, Valppu L, Taniyama Y, and Griendling KK. Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators. Circ Res 91: 406-413, 2002.
32. Soulet C, Gendreau S, Missy K, Benard V, Plantavid M, and Payrastre B. Characterisation of Rac activation in thrombin- and collagen-stimulated human blood platelets. FEBS Lett 507: 253-258, 2001.
33. Sreejayan N, Lin Y, and Hassid A. NO attenuates insulin signaling and motility in aortic smooth muscle cells via protein tyrosine phosphatase 1B-mediated mechanism. Arterioscler Thromb Vasc Biol 22: 1086-1092, 2002.
34. Szöcs K, Lassègue B, Sorescu D, Hilenski LL, Valppu L, Couse TL, Wilcox JN, Quinn MT, Lambeth JD, and Griendling KK. Upregulation of nox-based NAD(P)H oxidases in restenosis after carotid injury. Arterioscler Thromb Vasc Biol 22: 21-27, 2002.
35. Takeya R and Sumimoto H. Molecular mechanism for activation of superoxide-producing NADPH oxidases. Mol Cells 16: 271-277, 2003.
36. Tzima E, Del Pozo MA, Kiosses WB, Mohamed SA, Li S, Chien S, and Schwartz MA. Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression. EMBO J 21: 6791-6800, 2002.
37. Vermeersch P, Nong Z, Stabile E, Varenne O, Gillijns H, Pellens M, Van Pelt N, Hoylaerts M, De Scheerder I, Collen D, and Janssens S. L-Arginine administration reduces neointima formation after stent injury in rats by a nitric oxide-mediated mechanism. Arterioscler Thromb Vasc Biol 21: 1604-1609, 2001.
38. Von der Leyen HE, Gibbons GH, Morishita R, Lewis NP, Zhang L, Nakajima M, Kaneda Y, Cooke JP, and Dzau VJ. Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene. Proc Natl Acad Sci USA 92: 1137-1141, 1995.
39. Weintraub NL. Nox response to injury. Arterioscler Thromb Vasc Biol 22: 4-5, 2002.
40. 4 stimulates Rac-ERK cascade to generate reactive oxygen species that mediates chemotaxis. J Biol Chem 277: 8572-8578, 2002.
41. Yin ZL and Dusting GJ. A nitric oxide donor (spermine-NONOate) prevents the formation of neointima in rabbit carotid artery. Clin Exp Pharmacol Physiol 24: 436-438, 1997.
42. Yumi K, Fagin JA, Yamashita M, Fishbein MC, Shah PK, Kaul S, Niu W, Nilsson J, and Cercek B. Direct effects of somatostatin analog octreotide on insulin-like growth factor-I in the arterial wall. Lab Invest 76: 329-338, 1997.
43. Zhu B, Zhao G, Witte DP, Hui DY, and Fagin JA. Targeted overexpression of IGF-I in smooth muscle cells of transgenic mice enhances neointimal formation through increased proliferation and cell migration after intraarterial injury. Endocrinology 142: 3598-3606, 2001.
44. 2 levels: essential role of cGMP. Am J Physiol Heart Circ Physiol 286: H2103-H2112, 2004.