Transplantation of Cryopreserved Human Bone Marrow-derived Multipotent Adult Progenitor Cells for Neonatal Hypoxic-Ischemic Injury: Targeting the Hippocampus

Reviews in the Neurosciences

Volumn 17, Issue 1-2, 2006, Pages 215-226

  Yasuhara, Takao ^a   Matsukawa, Noriyuki ^a   Yu, Guolong ^a   Xu, Lin ^a   Mays, Robert W ^b   Kovach, Jim ^b   Deans, Robert ^b   Hess, David C ^c   Carroll, James E ^a   Borlongan, Cesar V ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b ATHERSYS INC   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

allogeneic grafts; motor behavior; neurogenesis; neurotrophic factor; progenitor cells; stem cells; syngeneic grafts

Indexed keywords

DRUG VEHICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; BRAIN ISCHEMIA; CELL DIFFERENTIATION; COMMON CAROTID ARTERY; CONTROLLED STUDY; CRYOPRESERVATION; GRAFT SURVIVAL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MOTOR PERFORMANCE; MULTIPOTENT STEM CELL; NONHUMAN; PRIORITY JOURNAL; RAT; STEM CELL TRANSPLANTATION; SURVIVAL TIME;

ANIMALS; ANIMALS, NEWBORN; ASPHYXIA NEONATORUM; CRYOPRESERVATION; DISEASE MODELS, ANIMAL; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HIPPOCAMPUS; HUMANS; HYPOXIA-ISCHEMIA, BRAIN; IMMUNOSUPPRESSION; INFANT, NEWBORN; MOTOR ACTIVITY; RATS; RATS, INBRED F344; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME;

EID: 33646408761     PISSN: 03341763     EISSN: None     Source Type: Journal    
DOI: 10.1515/revneuro.2006.17.1-2.215     Document Type: Article

References (40)

1. Ader M, Schachner M, Bartsch U. Integration and differentiation of neural stem cells after transplantation into the dysmyelinated central nervous system of adult mice. Eur J Neurosci 2004; 20: 1205-1210.
2. Baez JC, Gajavelli S, Thomas CK, Grumbles RM, Aparicio B, Byer D, et al. Embryonic cerebral cortex cells retain CNS phenotypes after transplantation into peripheral nerve. Exp Neurol 2004; 189: 422-425.
3. Borolongan CV, Emerich DF, Hoffer BJ, Bartus RT. Bradykinin receptor agonist facilitates low-dose cyclosporine-A protection against 6- hydroxydopamine neurotoxicity. Brain Res 2002; 956: 211-220.
4. Borlongan CV, Hadman M, Sanberg CD, Sanberg PR. Central nervous system entry of peripherally injected umbilical cord blood cells is not required for neuroprotection in stroke. Stroke 2004; 35: 2385-2389.
5. Borlongan CV, Lind JG, Dillon-Carter O, Yu G, Hadman M, Cheng C, et al. Bone marrow grafts restore cerebral blood flow and blood brain barrier in stroke rats. Brain Res 2004; 1010: 108-116.
6. Borlongan CV, Saporta S, Poulos SG, Othberg A, Sanberg PR. Viability and survival of hNT neurons determine degree of functional recovery in grafted ischemic rats. NeuroReport 1998; 9: 2837-2842.
7. Borlongan CV, Skinner SJ, Geaney M, Vasconcellos AV, Elliott RB, Emerich DF. Intracerebral transplantation of porcine choroid plexus provides structural and functional neuroprotection in a rodent model of stroke. Stroke 2004; 35: 2206-2210.
8. Borlongan CV, Tajima, Y, Trojanowski JQ, Lee VM, Sanberg PR. Cerebral ischemia and CNS transplantation: differential effects of grafted fetal rat striatal cells and human neurons derived from a clonal cell line. NeuroReport 1998; 9: 3703-3709.
9. Cai Z, Xiao F, Lee B, Paul IA, Rhodes PG. Prenatal hypoxia-ischemia alters expression and activity of nitric oxide synthase in the young rat brain and causes learning deficits. Brain Res Bull 1999; 49: 359-365.
10. Chu K, Kim M, Jung KH, Jeon D, Lee ST, Kim J, et al. Human neural stem cell transplantation reduces spontaneous recurrent seizures following pilocarpine-induced status epilepticus in adult rats. Brain Res 2004; 1023: 213-221.
11. Chu K, Kim M, Park KI, Jeong SW, Park HK, Jung KH, et al. Human neural stem cells improve sensorimotor deficits in the adult rat brain with experimental focal ischemia. Brain Res 2004; 1016: 145-153.
12. Davenport R, Dennis M. Neurological emergencies: acute stroke. J Neurol Neurosurg Psychiatry 2000; 68: 277-288.
13. Friedman WJ, Olson L, Persson H. Cells that express brain-derived neurotrophic factor mRNA in the developing postnatal rat brain. Eur J Neurosci 1991; 3: 688-697.
14. Fujiwara Y, Tanaka N, Ishida O, Fujimoto Y, Murakami T, Kajihara H, et al. Intravenously injected neural progenitor cells of transgenic rats can migrate to the injured spinal cord and differentiate into neurons, astrocytes and oligodendrocytes. Neurosci Lett 2004; 366: 287-291.
15. Hess DC, Hill WD, Martin-Studdard A, Carothers J, Brailer J, Carroll J. Blood into brain after stroke. Trends Mol Med 2002; 8: 452-453.
16. Hossain MA, Russell JC, O'Brien R, Laterra J. Neuronal pentraxin 1: a novel mediator of hypoxicischemic injury in neonatal brain. J Neurosci 2004; 24: 4187-4196.
17. Jansen EM, Low WC. Long-term effects of neonatal ischemic-hypoxic brain injury on sensorimotor and locomotor tasks in rats. Behav Brain Res 1996; 78: 189-194.
18. Jansen EM, Solberg L, Underhill S, Wilson S, Cozzari C, Hartman BK, et al. Transplantation of fetal neocortex ameliorates sensorimotor and locomotor deficits following neonatal ischemic-hypoxic brain injury in rats. Exp Neurol 1997; 147: 487-497.
19. Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418: 41-49.
20. Keene CD, Ortiz-Gonzalez XR, Jiang Y, Largaespada DA, Verfaillie CM, Low WC. Neural differentiation and incorporation of bone marrow-derived multipotent adult progenitor cells after single cell transplantation into blastocyst stage mouse embryos. Cell Transplant 2003; 12: 201-213.
21. Keep M, Elmer E, Fong KS, Csiszar K. Intrathecal cyclosporin prolongs survival of late-stage ALS mice. Brain Res 2001; 894: 327-331.
22. Kelly S, Bliss TM, Shah AK, Sun GH, Ma M, Foo WC, et al. Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. Proc Natl Acad Sci USA 2004; 101: 11839-11844.
23. Kim DW. Efficient induction of dopaminergic neurons from embryonic stem cells for application to Parkinson's disease. Yonsei Med J 2004; 45 (Suppl): 23-27.
24. Kim JH, Auerbach JM, Rodriguez-Gomez JA, Velasco I, Gavin D, Lumelsky N, et al. Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. Nature 2002; 418: 50-56.
25. Kogler G, Sensken S, Airey JA, Trapp T, Muschen M, Feldhahn N, et al. A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential. J Exp Med 2004; 200: 123-135.
26. Kokaia Z, Nawa H, Uchino H, Elmer K, Kokaia M, Carnahan J, Smith ML, Siesjo BK, Lindvall O. Brain Res Mol Brain Res 1996; 38: 139-144.
27. Kumral A, Uysal N, Tugyan K, Sonmez A, Yilmaz O, Gokmen N, et al. Erythropoietin improves long-term spatial memory deficits and brain injury following neonatal hypoxia-ischemia in rats. Behav Brain Res 2004; 153: 77-86.
28. Lindvall O, Kokaia Z, Martinez-Serrano A. Stem cell therapy for human neurodegenerative disorders-how to make it work. Nat Med 2004; 10 (Suppl): S42-50.
29. Marchionini DM, Collier TJ, Camargo M, McGuire S, Pitzer M, Sortwell CE. Interference with anoikis-induced cell death of dopamine neurons: implications for augmenting embryonic graft survival in a rat model of Parkinson's disease. J Comp Neurol 2003; 464: 172-179.
30. Marchionini DM, Collier TJ, Pitzer MR, Sortwell CE. Reassessment of caspase inhibition to augment grafted dopamine neuron survival. Cell Transplant 2004; 13: 273-282.
31. Mishima K, Ikeda T, Yoshikawa T, Aoo N, Egashira N, Xia YX, et al. Effects of hypothermia and hyperthermia on attentional and spatial learning deficits following neonatal hypoxia-ischemic insult in rats. Behav Brain Res 2004; 151: 209-217.
32. Olson EE, McKeon RJ. Characterization of cellular and neurological damage following unilateral hypoxia/ischemia. J Neurol Sci 2004; 227: 7-19.
33. Rice JEI, Vannucci RC, Brierley JB. The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann Neurol 1981; 9: 131-141.
34. Silani V, Cova L, Corbo M, A. Ciammola A, Polli E. Stem-cell therapy for amyotrophic lateral sclerosis. Lancet 2004; 364: 200-202.
35. Sortwell CE, Camargo MD, Pitzer MR, Gyawali S, Collier TJ. Diminished survival of mesencephalic dopamine neurons grafted into aged hosts occurs during the immediate postgrafting interval. Exp Neurol 2001; 169: 23-29.
36. Sortwell CE. Strategies for the augmentation of grafted dopamine neuron survival. Front Biosci 2003; 8: 522-532.
37. Szentirmai O, Carter BS. Genetic and cellular therapies for cerebral infarction. Neurosurgery 2004; 55: 283-286.
38. Tsukahara T, Iihara K, Hashimoto N, Nishijima T, Taniguchi T. Increases in levels of brain-derived neurotrophic factor mRNA and its promoters after transient forebrain ischemia in the rat brain. Neurochem Int 1998; 33: 201-207.
39. Uchino H, Minamikawa-Tachino R, Kristian T, Perkins G, Narazaki M, Siesjo BK, et al. Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition. Neurobiol Dis 2002; 10: 219-233.
40. Wang X, Lu Y, Zhang H, Wang K, He Q, Wang Y, et al. Distinct efficacy of pre-differentiated versus intact fetal mesencephalon-derived human neural progenitor cells in alleviating rat model of Parkinson's disease. Int J Dev Neurosci 2004; 22: 175-183.