-
1
-
-
0031755148
-
Nuclear factor κ B: A pivotal role in the systemic inflammatory response syndrome and new target for therapy
-
Christman JW, Lancaster LH, Blackwell TS (1998) Nuclear factor κ B: a pivotal role in the systemic inflammatory response syndrome and new target for therapy. Intensive Care Med 24:1131-1138
-
(1998)
Intensive Care Med
, vol.24
, pp. 1131-1138
-
-
Christman, J.W.1
Lancaster, L.H.2
Blackwell, T.S.3
-
2
-
-
0037247748
-
Nuclear factor-κB as a therapeutic target in critical care medicine
-
Zingarelli B, Sheehan M, Wong HR (2003) Nuclear factor-κB as a therapeutic target in critical care medicine. Crit Care Med 31:S105-S111
-
(2003)
Crit Care Med
, vol.31
-
-
Zingarelli, B.1
Sheehan, M.2
Wong, H.R.3
-
3
-
-
0031593456
-
Nuclear factor κ B - A new therapeutic approach?
-
Böhrer H, Nawroth PP (1998) Nuclear factor κ B - a new therapeutic approach? Intensive Care Med 24:1129-1130
-
(1998)
Intensive Care Med
, vol.24
, pp. 1129-1130
-
-
Böhrer, H.1
Nawroth, P.P.2
-
5
-
-
0036275030
-
Inhibition of nuclear factor-kappaB actication by IRFI 042 protects against endotoxin-induced shock
-
Altavilla D, Squadrito G, Minutoli L, Deodato B, Bova A, Sardella A, Seminara P, Passaniti M, Urna G, Venuti SF, Caputi AP, Squadrito F (2002) Inhibition of nuclear factor-kappaB actication by IRFI 042 protects against endotoxin-induced shock. Cardiovasc Res 54:684-693
-
(2002)
Cardiovasc Res
, vol.54
, pp. 684-693
-
-
Altavilla, D.1
Squadrito, G.2
Minutoli, L.3
Deodato, B.4
Bova, A.5
Sardella, A.6
Seminara, P.7
Passaniti, M.8
Urna, G.9
Venuti, S.F.10
Caputi, A.P.11
Squadrito, F.12
-
6
-
-
18344370479
-
2, attenuates the development of acute and chronic inflammation
-
2, attenuates the development of acute and chronic inflammation. Mol Pharmacol 61:997-1007
-
(2002)
Mol Pharmacol
, vol.61
, pp. 997-1007
-
-
Cuzzocrea, S.1
Wayman, N.S.2
Mazzon, E.3
Dugo, L.4
Di Paola, R.5
Serraino, I.6
Britti, D.7
Chatterjee, P.K.8
Caputi, A.P.9
Thiemermann, C.10
-
7
-
-
10744221054
-
Pyrrolidine dithiocarbamate attenuates the development of organ failure induced by zymosan in mice
-
Cuzzocrea S, Rossi A, Pisano B, Di Paola R, Genovese T, Patel NS, Cuzzocrea E, Iananro A, Sautebin L, Fulia F, Chatterjee PK, Caputi AP, Thiemermann C (2003) Pyrrolidine dithiocarbamate attenuates the development of organ failure induced by zymosan in mice. Intensive Care Med 29:2016-2025
-
(2003)
Intensive Care Med
, vol.29
, pp. 2016-2025
-
-
Cuzzocrea, S.1
Rossi, A.2
Pisano, B.3
Di Paola, R.4
Genovese, T.5
Patel, N.S.6
Cuzzocrea, E.7
Iananro, A.8
Sautebin, L.9
Fulia, F.10
Chatterjee, P.K.11
Caputi, A.P.12
Thiemermann, C.13
-
8
-
-
18844454813
-
2 attenuates development of zymosan-induced shock
-
2 attenuates development of zymosan-induced shock. Intensive Care Med 31:693-700
-
(2005)
Intensive Care Med
, vol.31
, pp. 693-700
-
-
Marzocco, S.1
Di Paola, R.2
Mazzon, E.3
Genovese, T.4
Britti, D.5
Pinto, A.6
Autore, G.7
Cuzzocrea, S.8
-
9
-
-
18844380247
-
Blockade of nuclear factor-κB activation prevents hypodynamic shock and gastric hypoperfusion induced by endotoxin in anesthetized dogs
-
Mitaka C, Hirata Y, Narumi Y, Yokoyama K, Makita K, Katsuyama K, Imai T (2005) Blockade of nuclear factor-κB activation prevents hypodynamic shock and gastric hypoperfusion induced by endotoxin in anesthetized dogs. Intensive Care Med 31:718-723
-
(2005)
Intensive Care Med
, vol.31
, pp. 718-723
-
-
Mitaka, C.1
Hirata, Y.2
Narumi, Y.3
Yokoyama, K.4
Makita, K.5
Katsuyama, K.6
Imai, T.7
-
10
-
-
0033163393
-
Is NF-κ B the sensor of oxidative stress?
-
Li N, Karin M (1999) Is NF-κ B the sensor of oxidative stress? FASEB J 12:1137-1143
-
(1999)
FASEB J
, vol.12
, pp. 1137-1143
-
-
Li, N.1
Karin, M.2
-
11
-
-
0036779617
-
Anti-inflammatory lipid mediators and insights into the resolution of inflammation
-
Lawrence T, Willoughby DA, Gilroy DW (2002) Anti-inflammatory lipid mediators and insights into the resolution of inflammation. Nat Rev Immunol 2:787-795
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 787-795
-
-
Lawrence, T.1
Willoughby, D.A.2
Gilroy, D.W.3
-
12
-
-
0344825796
-
NF-κB in critical diseases: A bad guy?
-
Senftleben U (2003) NF-κB in critical diseases: a bad guy? Intensive Care Med 29:1873-1876
-
(2003)
Intensive Care Med
, vol.29
, pp. 1873-1876
-
-
Senftleben, U.1
-
13
-
-
0037561557
-
12,14-PGJ2 and 2-cyclotenten-1-one: Role of the heat shock proteins
-
12,14-PGJ2 and 2-cyclotenten-1-one: role of the heat shock proteins. Mol Pharmacol 64:85-93
-
(2003)
Mol Pharmacol
, vol.64
, pp. 85-93
-
-
Ianaro, A.1
Ialenti, A.2
Maffia, P.3
Di Meglio, P.4
Di Rosa, M.5
Santoro, M.G.6
-
14
-
-
0034610759
-
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase
-
Rossi A, Kapahi P, Natoli G, Takahashi T, Chen Y, Karin M, Santoro MG (2000) Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase. Nature 403:103-108
-
(2000)
Nature
, vol.403
, pp. 103-108
-
-
Rossi, A.1
Kapahi, P.2
Natoli, G.3
Takahashi, T.4
Chen, Y.5
Karin, M.6
Santoro, M.G.7
-
15
-
-
0033000906
-
Inducible cyclooxygenase may have anti-inflammatory properties
-
Gilroy DW, Colville-Nash PR, Chivers WJ, Paul-Clark MJ, Willoughby DA (1999) Inducible cyclooxygenase may have anti-inflammatory properties. Nat Med 5:698-701
-
(1999)
Nat Med
, vol.5
, pp. 698-701
-
-
Gilroy, D.W.1
Colville-Nash, P.R.2
Chivers, W.J.3
Paul-Clark, M.J.4
Willoughby, D.A.5
-
16
-
-
10744223174
-
2, ligands of the peroxisome proliferator-activated receptor-g (PPAR-g), reduce ischemia/reperfusion injury of the gut
-
2, ligands of the peroxisome proliferator-activated receptor-g (PPAR-g), reduce ischemia/reperfusion injury of the gut. Br J Pharmacol 140:366-376
-
(2003)
Br J Pharmacol
, vol.140
, pp. 366-376
-
-
Cuzzocrea, S.1
Pisano, B.2
Dugo, L.3
Ianaro, A.4
Patel, N.S.5
Di Paola, R.6
Genovese, T.7
Chatterjee, P.K.8
Di Rosa, M.9
Caputi, A.P.10
Thiemermann, C.11
-
19
-
-
10744231560
-
2 ameliorates ischemic acute renal failure
-
2 ameliorates ischemic acute renal failure. Cardiovasc Res 61:630-643
-
(2004)
Cardiovasc Res
, vol.61
, pp. 630-643
-
-
Chatterjee, P.K.1
Patel, N.S.2
Cuzzocrea, S.3
Brown, P.A.4
Stewart, K.N.5
Mota-Filipe, H.6
Britti, D.7
Eberhardt, W.8
Pfeilschifter, J.9
Thiermermann, C.10
-
21
-
-
4444351825
-
2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria
-
2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria. Eur J Pharmacol 498:295-301
-
(2004)
Eur J Pharmacol
, vol.498
, pp. 295-301
-
-
Dugo, L.1
Collin, M.2
Cuzzocrea, S.3
Thiemermann, C.4
-
23
-
-
17644405062
-
Peroxisome proliferator-activated receptor-g is a new therapeutic target in sepsis and inflammation
-
Zingarelli B, Cook JA (2005) Peroxisome proliferator-activated receptor-g is a new therapeutic target in sepsis and inflammation. Shock 23:393-399
-
(2005)
Shock
, vol.23
, pp. 393-399
-
-
Zingarelli, B.1
Cook, J.A.2
-
24
-
-
0014607250
-
1; their actions on smooth muscle and their inactivation on passage through the pulmonary and hepatic portal vascular beds
-
1; their actions on smooth muscle and their inactivation on passage through the pulmonary and hepatic portal vascular beds. Br J Pharmacol 37:705-722
-
(1969)
Br J Pharmacol
, vol.37
, pp. 705-722
-
-
Horton, E.W.1
Jones, R.L.2
-
25
-
-
0017167573
-
Effects of prostaglandins in canine endotoxin shock
-
Shatney CH, Lillehei RC (1976) Effects of prostaglandins in canine endotoxin shock. Acta Biol Med Ger 35:1141-1149
-
(1976)
Acta Biol Med Ger
, vol.35
, pp. 1141-1149
-
-
Shatney, C.H.1
Lillehei, R.C.2
-
26
-
-
2442522508
-
HMR1402, a potassium ATP channel blocker during hyperdynamic porcine endotoxemia: Effects on hepato-splanchnic oxygen exchange and metabolism
-
Asfar P, Iványi Z, Bracht H, Hauser B, Pittner A, Vassilev D, Nalos M, Leverve XM, Brückner UB, Radermacher P, Fröba G (2004) HMR1402, a potassium ATP channel blocker during hyperdynamic porcine endotoxemia: effects on hepato-splanchnic oxygen exchange and metabolism. Intensive Care Med 30:957-964
-
(2004)
Intensive Care Med
, vol.30
, pp. 957-964
-
-
Asfar, P.1
Iványi, Z.2
Bracht, H.3
Hauser, B.4
Pittner, A.5
Vassilev, D.6
Nalos, M.7
Leverve, X.M.8
Brückner, U.B.9
Radermacher, P.10
Fröba, G.11
-
27
-
-
10744230633
-
Systemic, pulmonary, and hepatosplanchnic effects of N-acetylcysteine during long-term porcine endotoxemia
-
Vassilev D, Hauser B, Bracht H, Iványi Z, Schoaff M, Asfar P, Vogt J, Wachter U, Schelzig H, Georgieff M, Brückner UB, Radermacher P, Fröba G (2004) Systemic, pulmonary, and hepatosplanchnic effects of N-acetylcysteine during long-term porcine endotoxemia. Crit Care Med 32:525-532
-
(2004)
Crit Care Med
, vol.32
, pp. 525-532
-
-
Vassilev, D.1
Hauser, B.2
Bracht, H.3
Iványi, Z.4
Schoaff, M.5
Asfar, P.6
Vogt, J.7
Wachter, U.8
Schelzig, H.9
Georgieff, M.10
Brückner, U.B.11
Radermacher, P.12
Fröba, G.13
-
28
-
-
0034057069
-
Peroxisome proliferators-activated receptors in the cardiovascular systems
-
Bishop-Bailey D (2000) Peroxisome proliferators-activated receptors in the cardiovascular systems. Br J Pharmacol 129:823-834
-
(2000)
Br J Pharmacol
, vol.129
, pp. 823-834
-
-
Bishop-Bailey, D.1
-
29
-
-
0034975025
-
Overexpression of cardiac I-κ Bα prevents endotoxin-induced myocardial dysfunction
-
Haudek SB, Spencer E, Bryant DD, White DJ, Maass D, Horton JW, Chen ZJ, Giroir BP (2001) Overexpression of cardiac I-κ Bα prevents endotoxin-induced myocardial dysfunction. Am J Physiol Heart Circ Physiol 280:H962-H968
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.280
-
-
Haudek, S.B.1
Spencer, E.2
Bryant, D.D.3
White, D.J.4
Maass, D.5
Horton, J.W.6
Chen, Z.J.7
Giroir, B.P.8
-
30
-
-
0036314839
-
Ligands of the peroxisome proliferators-activated receptors (PPAR-γ and PPAR-α ) reduce myocardial infarct size
-
Wayman NS, Hattori Y, McDonald MC, Mota-Filipe H, Cuzzocrea S, Pisano B, Chatterjee PK, Thiemermann C (2002) Ligands of the peroxisome proliferators-activated receptors (PPAR-γ and PPAR-α ) reduce myocardial infarct size. FASEB J 16:1027-1040
-
(2002)
FASEB J
, vol.16
, pp. 1027-1040
-
-
Wayman, N.S.1
Hattori, Y.2
McDonald, M.C.3
Mota-Filipe, H.4
Cuzzocrea, S.5
Pisano, B.6
Chatterjee, P.K.7
Thiemermann, C.8
-
31
-
-
2942576050
-
Inhibition of the activation of nuclear factor kappa B to reduce myocardial reperfusion injury and infarct size
-
Thiemermann C (2004) Inhibition of the activation of nuclear factor kappa B to reduce myocardial reperfusion injury and infarct size. Cardiovasc Res 63:8-10
-
(2004)
Cardiovasc Res
, vol.63
, pp. 8-10
-
-
Thiemermann, C.1
-
32
-
-
2942547578
-
Inhibition of IkappaB phosphorylation in cardiomyocytes attenuates myocardial ischemia/reperfusion injury
-
Onai Y, Suzuki J, Kakuta T, Maejima Y, Haraguchi G, Fukasawa H, Muto S, Itai A, Isobe M (2004) Inhibition of IkappaB phosphorylation in cardiomyocytes attenuates myocardial ischemia/reperfusion injury. Cardiovasc Res 63:51-59
-
(2004)
Cardiovasc Res
, vol.63
, pp. 51-59
-
-
Onai, Y.1
Suzuki, J.2
Kakuta, T.3
Maejima, Y.4
Haraguchi, G.5
Fukasawa, H.6
Muto, S.7
Itai, A.8
Isobe, M.9
-
33
-
-
0034650330
-
Activation of peroxisome proliferator-activated receptor g does not inhibit IL-6 or TNF-a responses of macrophages to lipolysaccharide in vitro or in vivo
-
Thieringer R, Fenyk-Melody JE, Le Grand CB, Shelton BA, Detmers PA, Somers EP, Carbin L, Moller DA, Wroght SD, Berger J (2000) Activation of peroxisome proliferator-activated receptor g does not inhibit IL-6 or TNF-a responses of macrophages to lipolysaccharide in vitro or in vivo. J Immunol 164:1046-1054
-
(2000)
J Immunol
, vol.164
, pp. 1046-1054
-
-
Thieringer, R.1
Fenyk-Melody, J.E.2
Le Grand, C.B.3
Shelton, B.A.4
Detmers, P.A.5
Somers, E.P.6
Carbin, L.7
Moller, D.A.8
Wroght, S.D.9
Berger, J.10
-
34
-
-
0036784066
-
Alveolar macrophage activation after trauma-hemorrhage and sepsis is dependent on NF-κB and MAPK/ERK mechanisms
-
Jarrar D, Kuebler JF, Rue LW, Matalon S, Wang P, Bland KI, Chaudry IH (2002) Alveolar macrophage activation after trauma-hemorrhage and sepsis is dependent on NF-κB and MAPK/ERK mechanisms. Am J Physiol 283:L799-L805
-
(2002)
Am J Physiol
, vol.283
-
-
Jarrar, D.1
Kuebler, J.F.2
Rue, L.W.3
Matalon, S.4
Wang, P.5
Bland, K.I.6
Chaudry, I.H.7
-
35
-
-
0041568647
-
LPS induces pulmonary intravascular macrophages producing inflammatory mediators via activating NF-κB
-
Chen ZT, Li SL, Cai EQ, Wu WL, Jin JS, Zhu B (2003) LPS induces pulmonary intravascular macrophages producing inflammatory mediators via activating NF-κB. J Cell Biochem 89:1206-1214
-
(2003)
J Cell Biochem
, vol.89
, pp. 1206-1214
-
-
Chen, Z.T.1
Li, S.L.2
Cai, E.Q.3
Wu, W.L.4
Jin, J.S.5
Zhu, B.6
-
36
-
-
0042736093
-
Amplification of the proinflammatory transcription factor cascade increases with severity of uncontrolled hemorrhage in swine
-
Brundage SI, Schreiber MA, Holcomb JB, Zautke N, Mastrangelo MA, Xq X, Macaitis J, Tweardy DJ (2003) Amplification of the proinflammatory transcription factor cascade increases with severity of uncontrolled hemorrhage in swine. J Surg Res 113:74-80
-
(2003)
J Surg Res
, vol.113
, pp. 74-80
-
-
Brundage, S.I.1
Schreiber, M.A.2
Holcomb, J.B.3
Zautke, N.4
Mastrangelo, M.A.5
Xq, X.6
Macaitis, J.7
Tweardy, D.J.8
-
37
-
-
22044450541
-
Exogenous nitric oxide modulates the systemic inflammatory response and improves kidney function after risk-situation abdomnial aortic surgery
-
Lozano FS, Lopez-Novoa JM, Rodriguez JM, Barros MB, Garcia-Criado FJ, Nicolas JL, Parreno A, Revilla J, Gomez-Alonso A (2005) Exogenous nitric oxide modulates the systemic inflammatory response and improves kidney function after risk-situation abdomnial aortic surgery. J Vasc Surg 42:129-129
-
(2005)
J Vasc Surg
, vol.42
, pp. 129-129
-
-
Lozano, F.S.1
Lopez-Novoa, J.M.2
Rodriguez, J.M.3
Barros, M.B.4
Garcia-Criado, F.J.5
Nicolas, J.L.6
Parreno, A.7
Revilla, J.8
Gomez-Alonso, A.9
-
38
-
-
0035853707
-
Cyclopentenone prostaglandins as potential inducers of oxidative stress
-
Kondo M, Oya-Ito T, Kumagai T, Toshihiko O, Uchida K (2001) Cyclopentenone prostaglandins as potential inducers of oxidative stress. J Biol Chem 276:12076-12083
-
(2001)
J Biol Chem
, vol.276
, pp. 12076-12083
-
-
Kondo, M.1
Oya-Ito, T.2
Kumagai, T.3
Toshihiko, O.4
Uchida, K.5
-
39
-
-
0037093959
-
A proinflammatory role for the cyclopentenone prostaglandins at low micromolar concentrations: Oxidative stress-induced extracellular signal-regulated kinase activation without NF-κB inhibition
-
Bureau F, Desmet C, Mélotte D, Jaspar F, Volanti C, Vanderplasschen A, Pastoret PP, Piette J, Lekeux P (2002) A proinflammatory role for the cyclopentenone prostaglandins at low micromolar concentrations: oxidative stress-induced extracellular signal-regulated kinase activation without NF-κB inhibition. J Immunol 168:5318-5325
-
(2002)
J Immunol
, vol.168
, pp. 5318-5325
-
-
Bureau, F.1
Desmet, C.2
Mélotte, D.3
Jaspar, F.4
Volanti, C.5
Vanderplasschen, A.6
Pastoret, P.P.7
Piette, J.8
Lekeux, P.9
|