Amplification of the proinflammatory transcription factor cascade increases with severity of uncontrolled hemorrhage in swine

Journal of Surgical Research

Volumn 113, Issue 1, 2003, Pages 74-80

  Brundage, Susan I ^a   Schreiber, Martin A ^b   Holcomb, John B ^c   Zautke, Nathan ^a   Mastrangelo, Mary Ann ^d   Xq, Xu ^d   Macaitis, Joe ^c   Tweardy, David J ^d  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Hemorrhage; Inflammatory cascade; Interleukin 6; Nuclear factor B; Proinflammatory cytokines; Shock, ischemia reperfusion injury; Signal transducer and activator of transcription 3 (Stat3); Signal transduction; Transcription factors; Trauma

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MESSENGER RNA; STAT3 PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BLEEDING; CONFERENCE PAPER; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DISEASE SEVERITY; EUTHANASIA; GEL MOBILITY SHIFT ASSAY; HEMORRHAGIC SHOCK; HYPOTHERMIA; LIVER INJURY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN ISOLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SPLENECTOMY; SWINE;

EID: 0042736093     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-4804(03)00129-X     Document Type: Conference Paper

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