Antisense oligonucleotides-induced local blockade of T-bet expression leads to airway inflammation in rats

Acta Pharmacologica Sinica

Volumn 27, Issue 5, 2006, Pages 561-567

  Wang, Gang ^a   Liu, Chun Tao ^a   Wang, Zeng Li ^a   Jiang, Li Li ^a   Yan, Cun Liang ^b   Luo, Feng Min ^a  

^a SICHUAN UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

Airway inflammation; Antisense oligonucleotides; GATA3 transcription factor; Interferon type II; Interleukin 4; Interleukin 5; T box expressed in T cells

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; GAMMA INTERFERON; INTERLEUKIN 4; INTERLEUKIN 5; OVALBUMIN; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC INFLAMMATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; LUNG LAVAGE; LYMPHOCYTIC INFILTRATION; NONHUMAN; PNEUMONIA; PROTEIN EXPRESSION; RAT; RECEPTOR BLOCKING; T LYMPHOCYTE ACTIVATION; WESTERN BLOTTING;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; FEMALE; GATA3 TRANSCRIPTION FACTOR; INTERFERON TYPE II; INTERFERON-GAMMA; INTERLEUKIN-4; INTERLEUKIN-5; LUNG; OLIGONUCLEOTIDES, ANTISENSE; OVALBUMIN; PNEUMONIA; RANDOM ALLOCATION; RATS; RATS, WISTAR; RNA, MESSENGER; T-BOX DOMAIN PROTEINS;

EID: 33646272202     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2006.00323.x     Document Type: Article

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