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Volumn 12, Issue 7 I, 2006, Pages 2216-2223

Antisense suppression of pygopus2 results in growth arrest of epithelial ovarian cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; PROTEIN PYGOPUS 2; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 33646258514     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-05-2433     Document Type: Article
Times cited : (60)

References (38)
  • 1
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • Reya T, Clevers H. Wnt signalling in stem cells and cancer. Nature 2005;434:843-50.
    • (2005) Nature , vol.434 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 2
    • 14944357138 scopus 로고    scopus 로고
    • Wnt, stem cells and cancer in the intestine
    • Pinto D, Clevers H. Wnt, stem cells and cancer in the intestine. Biol Cell 2005;97:185-96.
    • (2005) Biol Cell , vol.97 , pp. 185-196
    • Pinto, D.1    Clevers, H.2
  • 3
    • 12544252343 scopus 로고    scopus 로고
    • β-Catenin: A pivot between cell adhesion and Wnt signalling
    • Bienz M. β-Catenin: a pivot between cell adhesion and Wnt signalling. Curr Biol 2005;15:R64-7.
    • (2005) Curr Biol , vol.15
    • Bienz, M.1
  • 4
    • 0036713566 scopus 로고    scopus 로고
    • Pygopus encodes a nuclear protein essential for wingless/Wnt signaling
    • Belenkaya TY, Han C, Standley HJ, et al. Pygopus encodes a nuclear protein essential for wingless/Wnt signaling. Development 2002;129:4089-101.
    • (2002) Development , vol.129 , pp. 4089-4101
    • Belenkaya, T.Y.1    Han, C.2    Standley, H.J.3
  • 5
    • 0037023584 scopus 로고    scopus 로고
    • Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear β-catenin-TCF complex
    • Kramps T, Peter O, Brunner E, et al. Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear β-catenin-TCF complex. Cell 2002;109:47-60.
    • (2002) Cell , vol.109 , pp. 47-60
    • Kramps, T.1    Peter, O.2    Brunner, E.3
  • 6
    • 0036333382 scopus 로고    scopus 로고
    • Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila
    • Parker DS, Jemison J, Cadigan KM. Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila. Development 2002;129:2565-76.
    • (2002) Development , vol.129 , pp. 2565-2576
    • Parker, D.S.1    Jemison, J.2    Cadigan, K.M.3
  • 7
    • 0036097733 scopus 로고    scopus 로고
    • A new nuclear component of the Wnt signalling pathway
    • Thompson B, Townsley F, Rosin-Arbesfeld R, et al. A new nuclear component of the Wnt signalling pathway. Nat Cell Biol 2002;4:367-73.
    • (2002) Nat Cell Biol , vol.4 , pp. 367-373
    • Thompson, B.1    Townsley, F.2    Rosin-Arbesfeld, R.3
  • 8
    • 3242706980 scopus 로고    scopus 로고
    • Pygopus and Legless target Armadillo/β-catenin to the nucleus to enable its transcriptional co-activator function
    • Townsley FM, Cliffe A, Bienz M. Pygopus and Legless target Armadillo/β-catenin to the nucleus to enable its transcriptional co-activator function. Nat Cell Biol 2004;6:626-33.
    • (2004) Nat Cell Biol , vol.6 , pp. 626-633
    • Townsley, F.M.1    Cliffe, A.2    Bienz, M.3
  • 9
    • 4644290995 scopus 로고    scopus 로고
    • Identification and in vivo role of the Armadillo-Legless interaction
    • Hoffmans R, Basler K. Identification and in vivo role of the Armadillo-Legless interaction. Development 2004;131:4393-400.
    • (2004) Development , vol.131 , pp. 4393-4400
    • Hoffmans, R.1    Basler, K.2
  • 10
    • 21844437361 scopus 로고    scopus 로고
    • Pygopus and legless provide essential transcriptional coactivator functions to armadillo/β-catenin
    • Hoffmans R, Stadeli R, Basler K. Pygopus and legless provide essential transcriptional coactivator functions to armadillo/β-catenin. Curr Biol 2005;15:1207-11.
    • (2005) Curr Biol , vol.15 , pp. 1207-1211
    • Hoffmans, R.1    Stadeli, R.2    Basler, K.3
  • 11
    • 1242317058 scopus 로고    scopus 로고
    • Pygopus residues required for its binding to legless are critical for transcription and development
    • Townsley FM, Thompson B, Bienz M. Pygopus residues required for its binding to legless are critical for transcription and development. J Biol Chem 2004;279:5177-83.
    • (2004) J Biol Chem , vol.279 , pp. 5177-5183
    • Townsley, F.M.1    Thompson, B.2    Bienz, M.3
  • 12
    • 0037388638 scopus 로고    scopus 로고
    • Small interfering RNAs directed against β-catenin inhibit the in vitro and in vivo growth of colon cancer cells
    • Verma UN, Surabhi RM, Schmaltieg A, et al. Small interfering RNAs directed against β-catenin inhibit the in vitro and in vivo growth of colon cancer cells. Clin Cancer Res 2003;9:1291-300.
    • (2003) Clin Cancer Res , vol.9 , pp. 1291-1300
    • Verma, U.N.1    Surabhi, R.M.2    Schmaltieg, A.3
  • 13
    • 9144269759 scopus 로고    scopus 로고
    • Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells
    • U S A
    • Li Y, Welm B, Podsypanina K, et al. Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells. Proc Natl Acad Sci U S A 2003;100:15853-8.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 15853-15858
    • Li, Y.1    Welm, B.2    Podsypanina, K.3
  • 14
    • 19444384545 scopus 로고    scopus 로고
    • β-catenin expression, DNA ploidy and clinicopathological features in ovarian cancer: A study in 253 patients
    • Kildal W, Risberg B, Abeler VM, et al. β-catenin expression, DNA ploidy and clinicopathological features in ovarian cancer: a study in 253 patients. Eur J Cancer 2005;41:1127-34.
    • (2005) Eur J Cancer , vol.41 , pp. 1127-1134
    • Kildal, W.1    Risberg, B.2    Abeler, V.M.3
  • 15
    • 0032054206 scopus 로고    scopus 로고
    • Mutations in the β-catenin gene (CTNNB1) in endometrioid ovarian carcinomas
    • Palacios J, Gamallo C. Mutations in the β-catenin gene (CTNNB1) in endometrioid ovarian carcinomas. Cancer Res 1998;58:1344-7.
    • (1998) Cancer Res , vol.58 , pp. 1344-1347
    • Palacios, J.1    Gamallo, C.2
  • 16
    • 0035890615 scopus 로고    scopus 로고
    • Diverse mechanisms of β-catenin deregulation in ovarian endometrioid adenocarcinomas
    • Wu R, Zhai Y, Fearon ER, et al. Diverse mechanisms of β-catenin deregulation in ovarian endometrioid adenocarcinomas. Cancer Res 2001;61:8247-55.
    • (2001) Cancer Res , vol.61 , pp. 8247-8255
    • Wu, R.1    Zhai, Y.2    Fearon, E.R.3
  • 17
    • 0036107888 scopus 로고    scopus 로고
    • Role of β-catenin/ T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas
    • Zhai Y, Wu R, Schwartz DR, et al. Role of β-catenin/ T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas. Am J Pathol 2002;160:1229-38.
    • (2002) Am J Pathol , vol.160 , pp. 1229-1238
    • Zhai, Y.1    Wu, R.2    Schwartz, D.R.3
  • 18
    • 0021740843 scopus 로고
    • Human ovarian surface epithelium in primary culture
    • Auersperg N, Siemens CH, Myrdal SE. Human ovarian surface epithelium in primary culture. In Vitro 1984;20:743-55.
    • (1984) In Vitro , vol.20 , pp. 743-755
    • Auersperg, N.1    Siemens, C.H.2    Myrdal, S.E.3
  • 19
    • 0041661953 scopus 로고    scopus 로고
    • Pygopus is required for embryonic brain patterning in Xenopus
    • Lake BB, Kao KR. Pygopus is required for embryonic brain patterning in Xenopus. Dev Biol 2003;261:132-48.
    • (2003) Dev Biol , vol.261 , pp. 132-148
    • Lake, B.B.1    Kao, K.R.2
  • 20
    • 0028893078 scopus 로고
    • Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation
    • Ju ST, Panka DJ, Cui H, et al. Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 1995;373:444-8.
    • (1995) Nature , vol.373 , pp. 444-448
    • Ju, S.T.1    Panka, D.J.2    Cui, H.3
  • 21
    • 0030039568 scopus 로고    scopus 로고
    • Developmental expression of functional GABAA receptors containing the γ2 subunit in neurons derived from embryonal carcinoma (P19) cells
    • Reynolds JN, Prasad A, Gillespie LL, et al. Developmental expression of functional GABAA receptors containing the γ2 subunit in neurons derived from embryonal carcinoma (P19) cells. Mol Brain Res 1996;35:11-8.
    • (1996) Mol Brain Res , vol.35 , pp. 11-18
    • Reynolds, J.N.1    Prasad, A.2    Gillespie, L.L.3
  • 22
    • 0035922110 scopus 로고    scopus 로고
    • Prognostic significance of BAG-1 expression in nonsmall cell lung cancer
    • Rorke S, Murphy, S, Khalifa, M, et al. Prognostic significance of BAG-1 expression in nonsmall cell lung cancer. lnt J Cancer 2001;95:317-22.
    • (2001) lnt J Cancer , vol.95 , pp. 317-322
    • Rorke, S.1    Murphy, S.2    Khalifa, M.3
  • 23
    • 0036931997 scopus 로고    scopus 로고
    • A human ovarian carcinoma murine xenograft model useful for preclinical trials
    • Elkas JC, Baldwin RL, Pegram M, et al. A human ovarian carcinoma murine xenograft model useful for preclinical trials. Gynecol Oncol 2002;87:200-6.
    • (2002) Gynecol Oncol , vol.87 , pp. 200-206
    • Elkas, J.C.1    Baldwin, R.L.2    Pegram, M.3
  • 24
    • 0037343163 scopus 로고    scopus 로고
    • β-catenin nuclear localization is associated with grade in ovarian serous carcinoma
    • Lee CM, Shvartsman H, Deavers MT, et al. β-catenin nuclear localization is associated with grade in ovarian serous carcinoma. Gynecol Oncol 2003;88:363-8.
    • (2003) Gynecol Oncol , vol.88 , pp. 363-368
    • Lee, C.M.1    Shvartsman, H.2    Deavers, M.T.3
  • 25
    • 13244256870 scopus 로고    scopus 로고
    • Origins and molecular pathology of ovarian cancer
    • Bell DA Origins and molecular pathology of ovarian cancer. Mod Pathol 2005;18 Suppl 2:S19-32.
    • (2005) Mod Pathol , vol.18 , Issue.2 SUPPL.
    • Bell, D.A.1
  • 27
    • 4644352441 scopus 로고    scopus 로고
    • Loss of β-catenin is associated with poor survival in ovarian carcinomas
    • Faleiro-Rodrigues C, Macedo-Pinto I, Pereira D, et al. Loss of β-catenin is associated with poor survival in ovarian carcinomas. Int J Gynecol Pathol 2004;23:337-46.
    • (2004) Int J Gynecol Pathol , vol.23 , pp. 337-346
    • Faleiro-Rodrigues, C.1    Macedo-Pinto, I.2    Pereira, D.3
  • 28
    • 23844452045 scopus 로고    scopus 로고
    • Biological relevance of E-cadherin-catenin complex proteins in primary epithelial ovarian tumors
    • Faleiro-Rodrigues C, Macedo-Pinto IM, Maia SS, et al. Biological relevance of E-cadherin-catenin complex proteins in primary epithelial ovarian tumors. Gynecol Obstet Invest 2005;60:75-83.
    • (2005) Gynecol Obstet Invest , vol.60 , pp. 75-83
    • Faleiro-Rodrigues, C.1    Macedo-Pinto, I.M.2    Maia, S.S.3
  • 29
    • 0036270763 scopus 로고    scopus 로고
    • The subcellular destinations of APC proteins
    • Bienz M. The subcellular destinations of APC proteins. Nat Rev Mol Cell Biol 2002;3:328-38.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 328-338
    • Bienz, M.1
  • 30
    • 1642499116 scopus 로고    scopus 로고
    • A divergent canonical WNT-signaling pathway regulates microtubule dynamics: Dishevelled signals locally to stabilize microtubules
    • Ciani L, Krylova O, Smalley MJ, et al. A divergent canonical WNT-signaling pathway regulates microtubule dynamics: dishevelled signals locally to stabilize microtubules. J Cell Biol 2004;164:243-53.
    • (2004) J Cell Biol , vol.164 , pp. 243-253
    • Ciani, L.1    Krylova, O.2    Smalley, M.J.3
  • 31
    • 1242339608 scopus 로고    scopus 로고
    • Targeted therapy for epithelial ovarian cancer: Current status and future prospects
    • See HT, Kavanagh JJ, Hu W, Bast RC. Targeted therapy for epithelial ovarian cancer: current status and future prospects. Int J Gynecol Cancer 2003;13:701-34.
    • (2003) Int J Gynecol Cancer , vol.13 , pp. 701-734
    • See, H.T.1    Kavanagh, J.J.2    Hu, W.3    Bast, R.C.4
  • 32
    • 20344371233 scopus 로고    scopus 로고
    • Antisense therapy for cancer
    • Gleave ME, Monia BP. Antisense therapy for cancer. Nat Rev Cancer 2005;5:468-79.
    • (2005) Nat Rev Cancer , vol.5 , pp. 468-479
    • Gleave, M.E.1    Monia, B.P.2
  • 33
    • 0030044172 scopus 로고    scopus 로고
    • p53 gene mutation analysis and antisense-mediated growth inhibition of human ovarian carcinoma cell lines
    • Skilling JS, Squatrito RC, Connor JP, et al. p53 gene mutation analysis and antisense-mediated growth inhibition of human ovarian carcinoma cell lines. Gynecol Oncol 1996;60:72-80.
    • (1996) Gynecol Oncol , vol.60 , pp. 72-80
    • Skilling, J.S.1    Squatrito, R.C.2    Connor, J.P.3
  • 34
    • 24644436544 scopus 로고    scopus 로고
    • Induction of apoptosis in human ovarian epithelial cancer cells by antisurvivin oligonucleotides
    • Ma X, Wang S, Zhou J, et al. Induction of apoptosis in human ovarian epithelial cancer cells by antisurvivin oligonucleotides. Oncol Rep 2005;14:275-9.
    • (2005) Oncol Rep , vol.14 , pp. 275-279
    • Ma, X.1    Wang, S.2    Zhou, J.3
  • 35
    • 1642296647 scopus 로고    scopus 로고
    • Antisense oligonucleotide targeting of Raf-1: Importance of raf-1 mRNA expression levels and raf-1-dependent signaling in determining growth response in ovarian cancer
    • Mullen P, McPhillips F, MacLeod K, et al. Antisense oligonucleotide targeting of Raf-1: importance of raf-1 mRNA expression levels and raf-1-dependent signaling in determining growth response in ovarian cancer. Clin Cancer Res 2004;10:2100-8.
    • (2004) Clin Cancer Res , vol.10 , pp. 2100-2108
    • Mullen, P.1    McPhillips, F.2    MacLeod, K.3
  • 36
    • 0034104017 scopus 로고    scopus 로고
    • Apoptosis and chemoresistance in human ovarian cancer: Is Xiap a determinant?
    • Li J, Sasaki H, Sheng YL, et al. Apoptosis and chemoresistance in human ovarian cancer: is Xiap a determinant? Biol Signals Recept 2000;9:122-30.
    • (2000) Biol Signals Recept , vol.9 , pp. 122-130
    • Li, J.1    Sasaki, H.2    Sheng, Y.L.3
  • 37
    • 0036528184 scopus 로고    scopus 로고
    • Antisense oligodeoxynucleotides of human telomerse catalytic sub-unit inhibits telomerase activity and proliferation in SKOV3 and COC1
    • Yuan B, Mi R. [Antisense oligodeoxynucleotides of human telomerse catalytic sub-unit inhibits telomerase activity and proliferation in SKOV3 and COC1]. Zhonghua Fu Chan Ke Za Zhi 2002;37:198-201.
    • (2002) Zhonghua Fu Chan Ke Za Zhi , vol.37 , pp. 198-201
    • Yuan, B.1    Mi, R.2
  • 38
    • 0033980773 scopus 로고    scopus 로고
    • 2-5A antisense directed against telomerase RNA produces apoptosis in ovarian cancer cells
    • Kushner DM, Paranjape JM, Bandyopadhyay B, et al. 2-5A antisense directed against telomerase RNA produces apoptosis in ovarian cancer cells. Gynecol Oncol 2000;76:183-92.
    • (2000) Gynecol Oncol , vol.76 , pp. 183-192
    • Kushner, D.M.1    Paranjape, J.M.2    Bandyopadhyay, B.3


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