Benzo[b]thiophene-2-carboxamides and benzo[b]furan-2-carboxamides are potent antagonists of the human H3-receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 12, 2006, Pages 3162-3165

  Peschke, Bernd ^a   Bak, Sonja ^a   Hohlweg, Rolf ^a   Nielsen, Rita ^a   Viuff, Dorthe ^a   Rimvall, Karin ^a  

^a NOVO NORDISK A S   (Denmark)

Author keywords

Benzo b furan; Benzo b thiophene; hH3 receptor; Histamine 3 receptor

Indexed keywords

AMIDE; FURAN DERIVATIVE; HISTAMINE H3 RECEPTOR; THIOPHENE DERIVATIVE;

ARTICLE; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; RING CLOSING METATHESIS; SUBSTITUTION REACTION;

AMIDES; BENZENE; FURANS; HISTAMINE ANTAGONISTS; HUMANS; MOLECULAR STRUCTURE; RECEPTORS, HISTAMINE H3; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

EID: 33646183062     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.03.074     Document Type: Article

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