Aplysamine-1 and related analogs as histamine H3 receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 4, 2006, Pages 897-900

  Swanson, Devin M ^a   Wilson, Sandy J ^a   Boggs, Jamin D ^a   Xiao, Wei ^a   Apodaca, Richard ^a   Barbier, Ann J ^a   Lovenberg, Timothy W ^a   Carruthers, Nicholas I ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Aplysamine 1; H3 ligand; Histamine; Histamine H3 receptor; Histamine H3 receptor antagonists; Marine natural product; Neurotransmitter

Indexed keywords

APLYSAMINE 1; DES BROMOAPLYSAMINE 1; DIMETHYL (2 (4 (3 PIPERIDIN 1 YLPROPOXY)PHENYL)ETHYL)AMINE; HISTAMINE H3 RECEPTOR; HISTAMINE H3 RECEPTOR ANTAGONIST; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING KINETICS; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; DRUG EVALUATION, PRECLINICAL; HUMANS; LIGANDS; MOLECULAR STRUCTURE; RATS; RECEPTORS, HISTAMINE H3; STRUCTURE-ACTIVITY RELATIONSHIP; TYROSINE;

ANIMALIA;

EID: 30344458497     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.11.003     Document Type: Article

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