Design, synthesis, and structure-activity relationships of novel non- imidazole histamine H3 receptor antagonists

Journal of Medicinal Chemistry

Volumn 43, Issue 12, 2000, Pages 2362-2370

  Linney, Ian D ^a   Buck, Ildiko M ^a   Harper, Elaine A ^a   Kalindjian, S Barret ^a   Pether, Michael J ^a   Shankley, Nigel P ^a   Watt, Gillian F ^a   Wright, Paul T ^a  

^a James Black Foundation   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIMAPRIT; HISTAMINE H3 RECEPTOR; HISTAMINE H3 RECEPTOR ANTAGONIST; N (4 CHLOROBENZYL) N (6 PYRROLIDIN 1 YLHEXYL)GUANIDINE; N (4 CHLOROBENZYL) N (7 PYRROLIDIN 1 YLHEPTYL)GUANIDINE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; GUINEA PIG; NONHUMAN; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ANIMALS; BINDING, COMPETITIVE; CEREBRAL CORTEX; DIMAPRIT; DRUG DESIGN; GUANIDINES; GUINEA PIGS; HISTAMINE ANTAGONISTS; ILEUM; LIGANDS; MUSCLE CONTRACTION; PYRROLIDINES; RADIOLIGAND ASSAY; RECEPTORS, HISTAMINE H1; RECEPTORS, HISTAMINE H2; RECEPTORS, HISTAMINE H3; RECEPTORS, SIGMA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033918980     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990952j     Document Type: Article

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