The effects of albumin-coated microbubbles in DNA delivery mediated by therapeutic ultrasound

Journal of Controlled Release

Volumn 112, Issue 2, 2006, Pages 156-166

  Duvshani Eshet, Maayan ^a   Adam, Dan ^a   Machluf, Marcelle ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Bioeffects; Cavitation; Gene delivery; Optison; Therapeutic ultrasound

Indexed keywords

ACOUSTICS; BIODIVERSITY; CELL CULTURE; DNA; HIGH RESOLUTION ELECTRON MICROSCOPY; SURFACE ROUGHNESS; ULTRASONICS;

BIOEFFECTS; GENE DELIVERY; OPTISON; THERAPEUTIC ULTRASOUND;

PROTEINS;

ECHO CONTRAST MEDIUM; FS 069; HUMAN ALBUMIN; PLASMID DNA;

ACOUSTICS; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL VIABILITY; CONTROLLED STUDY; CYTOPLASM; DNA TRANSFECTION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG DNA INTERACTION; DRUG EFFECT; DRUG EFFICACY; DRUG UPTAKE; GENE DELIVERY SYSTEM; GENE TARGETING; MICROBUBBLE; NONHUMAN; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; ULTRASOUND;

ALBUMINS; ANIMALS; CELL LINE; CRICETINAE; DNA; DRUG CARRIERS; GREEN FLUORESCENT PROTEINS; LUCIFERASES, FIREFLY; MICROBUBBLES; MICROSCOPY, ELECTRON, SCANNING; TRANSFECTION; ULTRASONICS;

EID: 33646154009     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.02.013     Document Type: Article

References (52)

1. Kim H.J., Greenleaf J.F., Kinnick R.R., Bronk J.T., and Bolander M.E. Ultrasound mediated transfection of mammalian cells. Hum. Gene Ther. 7 11 (1996) 1339-1346
2. Tata D.B., Dunn F., and Tindall D.J. Selective clinical ultrasound signals mediate differential gene transfer and expression in two human prostate cancer cell lines: LnCap and PC-3. Biochem. Biophys. Res. Commun. 234 1 (1997) 64-67
3. Bao S., Thrall B.D., and Miller D.L. Transfection of a reporter plasmid into cultured cells by sonoporation in vitro. Ultrasound Med. Biol. 23 6 (1997) 953-959
4. Taniyama Y., Tachibana K., Hiraoka K., Aoki M., Yamamoto S., Matsumoto K., Nakamura T., Ogihara T., Kaneda Y., and Morishita R. Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle. Gene Ther. 9 6 (2002) 372-380
5. Joersbo M., and Brunstedt J. Protein synthesis stimulated in sonicated sugar beet cells and protoplasts. Ultrasound Med. Biol. 16 7 (1990) 719-724
6. Guzman H.R., Nguyen D.X., Khan S., and Prausnitz M.R. Ultrasound-mediated disruption of cell membranes. I. Quantification of molecular uptake and cell viability. J. Acoust. Soc. Am. 110 1 (2001) 588-596
7. Apfel R.E., and Holland C.K. Gauging the likelihood of cavitation from short-pulls, low-duty cycle diagnostic ultrasound. Ultrasound Med. Biol. 17 (1991) 179-185
8. Greenleaf W.J., Bolander M.E., Sarkar G., Goldring M.B., and Greenleaf J.F. Artificial cavitation nuclei significantly enhance acoustically induced cell transfection. Ultrasound Med. Biol. 24 4 (1998) 587-595
9. Ng K.Y., and Liu Y. Therapeutic ultrasound: its application in drug delivery. Med. Res. Rev. 22 2 (2002) 204-223
10. Miller M.W., Miller D.L., and Brayman A.A. A review of in vitro bioeffects of inertial ultrasonic cavitation from a mechanistic perspective. Ultrasound Med. Biol. 22 9 (1996) 1131-1154
11. Unger E.C., Hersh E., Vannan M., and McCreery T. Gene delivery using ultrasound contrast agents. Echocardiography 18 4 (2001) 355-361
12. Koch S., Pohl P., Cobet U., and Rainov N.G. Ultrasound enhancement of liposome-mediated cell transfection is caused by cavitation effects. Ultrasound Med. Biol. 26 5 (2000) 897-903
13. Liu J., Lewis T.N., and Prausnitz M.R. Non-invasive assessment and control of ultrasound-mediated membrane permeabilization. Pharm. Res. 15 6 (1998) 918-924
14. Ward M., Wu J., and Chiu J.F. Ultrasound-induced cell lysis and sonoporation enhanced by contrast agents. J. Acoust. Soc. Am. 105 5 (1999) 2951-2957
15. Lawrie A., Brisken A.F., Francis S.E., Tayler D.I., Chamberlain J., Crossman D.C., Cumberland D.C., and Newman C.M. Ultrasound enhances reporter gene expression after transfection of vascular cells in vitro. Circulation 99 20 (1999) 2617-2620
16. Unger E.C., McCreery T.P., and Sweitzer R.H. Ultrasound enhances gene expression of liposomal transfection. Invest. Radiol. 32 12 (1997) 723-727
17. Duvshani-Eshet M., and Machluf M. Therapeutic ultrasound optimization for gene delivery: a key factor achieving nuclear DNA localization. J. Control. Release 108 2-3 (2005) 513-528
18. Anwer K., Kao G., Proctor B., Anscombe I., Florack V., Earls R., Wilson E., McCreery T., Unger E., Rolland A., and Sullivan S.M. Ultrasound enhancement of cationic lipid-mediated gene transfer to primary tumors following systemic administration. Gene Ther. 7 21 (2000) 1833-1839
19. Lawrie A., Brisken A.F., Francis S.E., Cumberland D.C., Crossman D.C., and Newman C.M. Microbubble-enhanced ultrasound for vascular gene delivery. Gene Ther. 7 23 (2000) 2023-2027
20. Pislaru S.V., Pislaru C., Kinnick R.R., Singh R., Gulati R., Greenleaf J.F., and Simari R.D. Optimization of ultrasound-mediated gene transfer: comparison of contrast agents and ultrasound modalities. Eur. Heart J. 24 18 (2003) 1690-1698
21. Porter T.R., Oberdorfer J., Rafter P., Lof J., and Xie F. Microbubble responses to a similar mechanical index with different real-time perfusion imaging techniques. Ultrasound Med. Biol. 29 8 (2003) 1187
22. Stride E., and Saffari N. Microbubble ultrasound contrast agents: a review. Proc. Inst. Mech. Eng. 217 6 (2003) 429-447
23. Mehier-Humbert S., and Guy R.H. Physical methods for gene transfer: improving the kinetics of gene delivery into cells. Adv. Drug Deliv. Rev. 57 5 (2005) 733-753
24. Lawrie A., Brisken A.F., Francis S.E., Wyllie D., Kiss-Toth E., Qwarnstrom E.E., Dower S.K., Crossman D.C., and Newman C.M. Ultrasound-enhanced transgene expression in vascular cells is not dependent upon cavitation-induced free radicals. Ultrasound Med. Biol. 29 10 (2003) 1453-1461
25. Lu Q.L., Liang H.D., Partridge T., and Blomley M.J. Microbubble ultrasound improves the efficiency of gene transduction in skeletal muscle in vivo with reduced tissue damage. Gene Ther. 10 5 (2003) 396-405
26. Huber P.E., Mann M.J., Melo L.G., Ehsan A., Kong D., Zhang L., Rezvani M., Peschke P., Jolesz F., Dzau V.J., and Hynynen K. Focused ultrasound (HIFU) induces localized enhancement of reporter gene expression in rabbit carotid artery. Gene Ther. 10 18 (2003) 1600-1607
27. Endoh M., Koibuchi N., Sato M., Morishita R., Kanzaki T., Murata Y., and Kaneda Y. Fetal gene transfer by intrauterine injection with microbubble-enhanced ultrasound. Molec. Ther. 5 5 Pt 1 (2002) 501-508
28. Hashiya N., Aoki M., Tachibana K., Taniyama Y., Yamasaki K., Hiraoka K., Makino H., Yasufumi K., Ogihara T., and Morishita R. Local delivery of E2F decoy oligodeoxynucleotides using ultrasound with microbubble agent (Optison) inhibits intimal hyperplasia after balloon injury in rat carotid artery model. Biochem. Biophys. Res. Commun. 317 2 (2004) 508-514
29. Sakakima Y., Hayashi S., Yagi Y., Hayakawa A., Tachibana K., and Nakao A. Gene therapy for hepatocellular carcinoma using sonoporation enhanced by contrast agents. Cancer Gene Ther. 12 11 (2005) 884-889
30. Taniyama Y., Tachibana K., Hiraoka K., Namba T., Yamasaki K., Hashiya N., Aoki M., Ogihara T., Yasufumi K., and Morishita R. Local delivery of plasmid DNA into rat carotid artery using ultrasound. Circulation 105 (2002) 1233-1239
31. Miller D.L., and Song J. Lithotripter shock waves with cavitation nucleation agents produce tumor growth reduction and gene transfer in vivo. Ultrasound Med. Biol. 28 10 (2002) 1343-1348
32. Miller D.L., and Song J. Tumor growth reduction and DNA transfer by cavitation-enhanced high-intensity focused ultrasound in vivo. Ultrasound Med. Biol. 29 6 (2003) 887-893
33. Porter T.R., Iversen P.L., Li S., and Xie F. Interaction of diagnostic ultrasound with synthetic oligonucleotide-labeled perfluorocarbon-exposed sonicated dextrose albumin microbubbles. J. Ultrasound Med. 15 8 (1996) 577-584
34. Sundaram J., Mellein B.R., and Mitragotri S. An experimental and theoretical analysis of ultrasound-induced permeabilization of cell membranes. Biophys. J. 84 5 (2003) 3087-3101
35. Wang X., Liang H.D., Dong B., Lu Q.L., and Blomley M.J. Gene transfer with microbubble ultrasound and plasmid DNA into skeletal muscle of mice: comparison between commercially available microbubble contrast agents. Radiology 237 1 (2005) 224-229
36. Mehier-Humbert S., Bettinger T., Yan F., and Guy R.H. Ultrasound-mediated gene delivery: kinetics of plasmid internalization and gene expression. J. Control. Release 104 1 (2005) 203-211
37. Duvshani-Eshet M., Baruch L., Kesselman E., Shimoni E., and Machluf M. Therapeutic ultrasound-mediated DNA to cell and nucleus: bioeffects revealed by confocal and atomic force microscopy. Gene Ther. 13 2 (2006) 163-172
38. Zelphati O., Liang X., Hobart P., and Felgner P.L. Gene chemistry: functionally and conformationally intact fluorescent plasmid DNA. Hum. Gene Ther. 10 1 (1999) 15-24
39. Skyba D.M., Price R.J., Linka A.Z., Skalak T.C., and Kaul S. Direct in vivo visualization of intravascular destruction of microbubbles by ultrasound and its local effects on tissue. Circulation 98 4 (1998) 290-293
40. Frenkel P.A., Chen S., Thai T., Shohet R.V., and Grayburn P.A. DNA-loaded albumin microbubbles enhance ultrasound-mediated transfection in vitro. Ultrasound Med. Biol. 28 6 (2002) 817-822
41. Kamaev P.P., Hutcheson J.D., Wilson M.L., and Prausnitz M.R. Quantification of optison bubble size and lifetime during sonication dominant role of secondary cavitation bubbles causing acoustic bioeffects. J. Acoust. Soc. Am. 115 4 (2004) 1818-1825
42. Mestas J.L., Lenz P., and Cathignol D. Long-lasting stable cavitation. J. Acoust. Soc. Am. 113 3 (2003) 1426-1430
43. Husseini G.A., Diaz de la Rosa M.A., Richardson E.S., Christensen D.A., and Pitt W.G. The role of cavitation in acoustically activated drug delivery. J. Control. Release 107 2 (2005) 253-261
44. Ward M., Wu J., and Chiu J.F. Experimental study of the effects of Optison concentration on sonoporation in vitro. Ultrasound Med. Biol. 26 7 (2000) 1169-1175
45. Flynn H.G., and Church C.C. Transient pulsations of small gas bubbles in water. J. Acoust. Soc. Am. 84 5 (1988) 1863-1876
46. Li T., Tachibana K., and Kuroki M. Gene transfer with echo-enhanced contrast agents: comparison between Albunex, Optison, and Levovist in mice-initial results. Radiology 229 2 (2003) 423-428
47. Brayman A.A., and Miller M.W. Acoustic cavitation nuclei survive the apparent ultrasonic destruction of Albunex microspheres. Ultrasound Med. Biol. 23 5 (1997) 793-796
48. Miller D.L. Frequency relationships for ultrasonic activation of free microbubbles, encapsulated microbubbles, and gas-filled micropores. J. Acoust. Soc. Am. 104 4 (1998) 2498-2505
49. ter Haar G. Therapeutic ultrasound. Eur. J. Ultrasound 9 1 (1999) 3-9
50. Mehier-Humbert S., Bettinger T., Yan F., and Guy R.H. Plasma membrane poration induced by ultrasound exposure: implication for drug delivery. J. Control. Release 104 1 (2005) 213-222
51. Brayman A.A., Coppage M.L., Vaidya S., and Miller M.W. Transient poration and cell surface receptor removal from human lymphocytes in vitro by 1 MHz ultrasound. Ultrasound Med. Biol. 25 6 (1999) 999-1008
52. Deng C.X., Sieling F., Pan H., and Cui J. Ultrasound-induced cell membrane porosity. Ultrasound Med. Biol. 30 4 (2004) 519-526