Direct in vivo visualization of intravascular destruction of microbubbles by ultrasound and its local effects on tissue

Circulation

Volumn 98, Issue 4, 1998, Pages 290-293

  Skyba, Danny M ^a   Price, Richard J ^b   Linka, Andre Z ^a   Skalak, Thomas C ^b   Kaul, Sanjiv ^a,b,c  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF VIRGINIA MEDICAL CENTER   (United States)

Author keywords

Microspheres; Tissue; Ultrasonics

Indexed keywords

MICROSPHERE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL INJURY; CAPILLARY; CELL DAMAGE; CONTROLLED STUDY; ECHOGRAPHY; FEMALE; NONHUMAN; PRIORITY JOURNAL; RADIOBIOLOGY; RAT; ULTRASOUND;

EID: 0032575349     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.98.4.290     Document Type: Article

References (12)

1. Wei K, Skyba DM, Firschke C, Jayaweera AR, Lindner J, Kaul S. Interactions between microbubbles and ultrasound: in vitro and in vivo observations. J Am Coll Cardiol. 1997;29:1081-1088.
2. Dayton P, Morgan K, Allietta M, Klibanov A, Brandenberg G, Ferrara K. Simultaneous optical and acoustical observations of contrast agents. IEEE Ultrasonics Symposium. 1997;1583-1591.
3. Skyba DM, Camarano G, Goodman NC, Price RJ, Skalak TC, Kaul S. Hemodynamic characteristics, myocardial kinetics and microvascular rheology of FS-069, a second-generation echocardiographic contrast agent capable of producing myocardial opacification from a venous injection. J Am Coll Cardiol. 1996;28:1292-1300.
4. Harris AG, Skalak TC. Effects of leukocyte plugging in skeletal muscle ischemia-reperfusion injury. Am J Physiol. 1996;271:H2653-H2660.
5. Apfel RE. Acoustic cavitation: a possible consequence of biomedical uses of ultrasound. Br J Cancer. 1982;45(suppl):140-146.
6. Flynn H. Physics of acoustic cavitation in liquids. In: Mason WP, ed. Physical Acoustics. New York: Academic Press; 1964:57.
7. Neppiras EA, Noltingk BE. Cavitation produced by ultrasonics: theoretical conditions for the onset of cavitation. Proc Phys Soc. 1951; 664:1032.
8. Miller MW, Miller DL, Brayman AA. A review of in vitro bioeffects of inertial ultrasonic cavitation from a mechanistic perspective. Ultrasound Med Biol. 1996;22:1131-1154.
9. Dalecki D, Child SZ, Raeman CH, Cox C, Penney DP, Carstensen EL. Age-dependence of ultrasonically-induced lung hemorrhage in mice. Ultrasound Med Biol. 1996;23:917-925.
10. Dalecki D, Raeman CH, Child SZ, Cox C, Meltzer R, Carstensen EL. Hemolysis in vivo from exposure to pulsed ultrasound. Ultrasound Med Biol. 1997;23:307-313.
11. Hsiung HH, Skalak TC. Three-dimensional reconstruction of capillary networks in skeletal muscle. FASEB J. 1990;4:A1256. Abstract.
12. Meltzer RS, Adsumelli R, Risher WH, Hicks GL, Stern DH, Shah PM, Wojtczak JA, Lustik SJ, Gayeski TE, Shapiro JR, Carstensen EL. Lack of lung hemorrhage in humans after intraoperative transesophageal echocardiography with ultrasound exposure conditions similar to those causing lung hemorrhage in humans. J Am Soc Echocardiogr. 1998;11:57-60.