메뉴 건너뛰기




Volumn 106, Issue 8, 2006, Pages 1730-1738

t(3;21)(q26;q22) in myeloid leukemia: An aggressive syndrome of blast transformation associated with hydroxyurea or antimetabolite therapy

Author keywords

5 fluorouracil; Chronic myeloid leukemia; Etoposide; Fludarabine; Hydroxyurea; Therapy related leukemia

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ANAGRELIDE; BUSULFAN; CD34 ANTIGEN; CD7 ANTIGEN; CD9 ANTIGEN; CYCLOPHOSPHAMIDE; CYTARABINE; DASATINIB; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; FLUDARABINE; FLUOROURACIL; HYDROXYUREA; IDARUBICIN; IFOSFAMIDE; INTERFERON; MESNA; METHOTREXATE; MITOXANTRONE; NILOTINIB; PREDNISONE; THALIDOMIDE; TIPIFARNIB; TOPOTECAN; TRANSCRIPTION FACTOR RUNX1; TROXACITABINE; UNINDEXED DRUG; VINCRISTINE;

EID: 33646075159     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.21797     Document Type: Article
Times cited : (48)

References (28)
  • 1
    • 0036814971 scopus 로고    scopus 로고
    • Molecular genetics of human leukemias: New insights into therapy
    • Gilliland DG. Molecular genetics of human leukemias: new insights into therapy. Semin Hematol. 2002;39:6-11.
    • (2002) Semin Hematol , vol.39 , pp. 6-11
    • Gilliland, D.G.1
  • 2
    • 0037309377 scopus 로고    scopus 로고
    • The core-binding factor leukemias: Lessons learned from murine models
    • Downing JR. The core-binding factor leukemias: lessons learned from murine models. Curr Opin Genet Dev. 2003;13:48-54.
    • (2003) Curr Opin Genet Dev , vol.13 , pp. 48-54
    • Downing, J.R.1
  • 3
    • 0036636857 scopus 로고    scopus 로고
    • Core-binding factors in haematopoiesis and leukaemia
    • Speck NA, Gilliland DG. Core-binding factors in haematopoiesis and leukaemia. Nat Rev Cancer. 2002;2:502-513.
    • (2002) Nat Rev Cancer , vol.2 , pp. 502-513
    • Speck, N.A.1    Gilliland, D.G.2
  • 4
    • 0027183945 scopus 로고
    • The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1
    • Nucifora G, Begy CR, Erickson P, Drabkin HA, Rowley JD. The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1. Proc Natl Acad Sci U S A. 1993;90:7784-7788.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 7784-7788
    • Nucifora, G.1    Begy, C.R.2    Erickson, P.3    Drabkin, H.A.4    Rowley, J.D.5
  • 5
    • 0028069226 scopus 로고
    • Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia
    • Mitani K, Ogawa S, Tanaka T, et al. Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia. EMBO J. 1994;13:504-510.
    • (1994) EMBO J , vol.13 , pp. 504-510
    • Mitani, K.1    Ogawa, S.2    Tanaka, T.3
  • 6
    • 0028270494 scopus 로고
    • Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3; 21)(q26;q22) translocations
    • Nucifora G, Begy CR, Kobayashi H, et al. Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3; 21)(q26;q22) translocations. Proc Natl Acad Sci U S A. 1994;91:4004-4008.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 4004-4008
    • Nucifora, G.1    Begy, C.R.2    Kobayashi, H.3
  • 8
    • 18744408734 scopus 로고    scopus 로고
    • Mantle cell lymphoma with 8q24 chromosomal abnormalities: A report of 5 cases with blastoid features
    • Hao S, Sanger W, Onciu M, Lai R, Schlette EJ, Medeiros LJ. Mantle cell lymphoma with 8q24 chromosomal abnormalities: a report of 5 cases with blastoid features. Mod Pathol. 2002;15:1266-1272.
    • (2002) Mod Pathol , vol.15 , pp. 1266-1272
    • Hao, S.1    Sanger, W.2    Onciu, M.3    Lai, R.4    Schlette, E.J.5    Medeiros, L.J.6
  • 9
    • 2442653867 scopus 로고    scopus 로고
    • t(8;21)(q22;q22) in blast phase of chronic myelogenous leukemia
    • Yin CC, Medeiros LJ, Glassman AB, Lin P. t(8;21)(q22;q22) in blast phase of chronic myelogenous leukemia. Am J Clin Pathol. 2004;121:836-842.
    • (2004) Am J Clin Pathol , vol.121 , pp. 836-842
    • Yin, C.C.1    Medeiros, L.J.2    Glassman, A.B.3    Lin, P.4
  • 10
    • 0030053576 scopus 로고    scopus 로고
    • Rearrangement of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: Expression of co-existing multiple chimeric genes with similar functions as transcriptional repressors, but with opposite tumorigenic properties
    • Zent C, Kim N, Hiebert S, et al. Rearrangement of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: expression of co-existing multiple chimeric genes with similar functions as transcriptional repressors, but with opposite tumorigenic properties. Curr Top Microbiol Immunol. 1996;211:243-252,
    • (1996) Curr Top Microbiol Immunol , vol.211 , pp. 243-252
    • Zent, C.1    Kim, N.2    Hiebert, S.3
  • 11
    • 85047695549 scopus 로고    scopus 로고
    • The leukemia-associated transcription repressor AML1/MDS1/EVI1 requires CtBP to induce abnormal growth and differentiation of murine hematopoietic cells
    • Senyuk V, Chakraborty S, Mikhail FM, Zhao R, Chi Y, Nucifora G. The leukemia-associated transcription repressor AML1/MDS1/EVI1 requires CtBP to induce abnormal growth and differentiation of murine hematopoietic cells. Oncogene. 2002;21:3232-3240,
    • (2002) Oncogene , vol.21 , pp. 3232-3240
    • Senyuk, V.1    Chakraborty, S.2    Mikhail, F.M.3    Zhao, R.4    Chi, Y.5    Nucifora, G.6
  • 13
    • 4444254797 scopus 로고    scopus 로고
    • The leukemic fusion gene AML1-MDS1-EVI1 suppresses CEBPA in acute myeloid leukemia by activation of calreticulin
    • Helbling D, Mueller BU, Timchenko NA, et al. The leukemic fusion gene AML1-MDS1-EVI1 suppresses CEBPA in acute myeloid leukemia by activation of calreticulin. Proc Natl Acad Sci U S A. 2004;101:13312-13317.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13312-13317
    • Helbling, D.1    Mueller, B.U.2    Timchenko, N.A.3
  • 14
    • 0029867018 scopus 로고    scopus 로고
    • Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family
    • Fears S, Mathieu C, Zelezni-Le N, Huang S, Rowley JD, Nucifora G. Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family. Proc Natl Acad Sci U S A. 1996;93:1642-1647.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 1642-1647
    • Fears, S.1    Mathieu, C.2    Zelezni-Le, N.3    Huang, S.4    Rowley, J.D.5    Nucifora, G.6
  • 15
    • 0033014867 scopus 로고    scopus 로고
    • Nucifora G. MDS1/EVI1 enhances TGF-beta1 signaling and strengthens its growth-inhibitory effect but the leukemia-associated fusion protein AML1/MDS1/EVI1, product of the t(3;21), abrogates growth-inhibition in response to TGF-beta1
    • Sood R, Talwar-Trikha A, Chakrabarti SR., Nucifora G. MDS1/EVI1 enhances TGF-beta1 signaling and strengthens its growth-inhibitory effect but the leukemia-associated fusion protein AML1/MDS1/EVI1, product of the t(3;21), abrogates growth-inhibition in response to TGF-beta1. Leukemia. 1999;13:348-357.
    • (1999) Leukemia , vol.13 , pp. 348-357
    • Sood, R.1    Talwar-Trikha, A.2    Chakrabarti, S.R.3
  • 16
    • 0029017631 scopus 로고
    • EVI-1 zinc finger protein works as a transcriptional activator via binding to a consensus sequence of GACAAGATAA-GATAAN1-28 CTCATCTTC
    • Morishita K, Suzukawa K, Taki T, Ihle JN, Yokota J. EVI-1 zinc finger protein works as a transcriptional activator via binding to a consensus sequence of GACAAGATAA-GATAAN1-28 CTCATCTTC. Oncogene. 1995;10:1961-1967.
    • (1995) Oncogene , vol.10 , pp. 1961-1967
    • Morishita, K.1    Suzukawa, K.2    Taki, T.3    Ihle, J.N.4    Yokota, J.5
  • 17
    • 2942602707 scopus 로고    scopus 로고
    • Molecular mechanisms of leukemogenesis by AML1/EVI-1
    • Mitani K. Molecular mechanisms of leukemogenesis by AML1/EVI-1. Oncogene. 2004;23:4263-4269.
    • (2004) Oncogene , vol.23 , pp. 4263-4269
    • Mitani, K.1
  • 19
    • 3242800443 scopus 로고    scopus 로고
    • Clonal evolution in chronic myelogenous leukemia
    • Cortes J, O'Dwyer ME. Clonal evolution in chronic myelogenous leukemia. Hematol Oncol Clin North Am. 2004;18:671-684.
    • (2004) Hematol Oncol Clin North Am , vol.18 , pp. 671-684
    • Cortes, J.1    O'Dwyer, M.E.2
  • 20
    • 0842329808 scopus 로고    scopus 로고
    • Both AML1 and EVI1 oncogenic components are required for the cooperation of AML1/MDS1/EVI1 with BCR/ABL in the induction of acute myelogenous leukemia in mice
    • Cuenco GM, Ren R, Both AML1 and EVI1 oncogenic components are required for the cooperation of AML1/MDS1/EVI1 with BCR/ABL in the induction of acute myelogenous leukemia in mice. Oncogene. 2004;23:569-579.
    • (2004) Oncogene , vol.23 , pp. 569-579
    • Cuenco, G.M.1    Ren, R.2
  • 21
    • 13544273521 scopus 로고    scopus 로고
    • Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML
    • Andersen MK, Christiansen DH, Pedersen-Bjergaard J. Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML. Leukemia. 2005;19:197-200.
    • (2005) Leukemia , vol.19 , pp. 197-200
    • Andersen, M.K.1    Christiansen, D.H.2    Pedersen-Bjergaard, J.3
  • 22
    • 0036197484 scopus 로고    scopus 로고
    • 21q22 balanced chromosome aberrations in therapy-related hematopoietic disorders: Report from an international workshop
    • Slovak ML, Bedell V, Popplewell L, Arber DA, Schoch C, Slater R. 21q22 balanced chromosome aberrations in therapy-related hematopoietic disorders: report from an international workshop. Genes Chromosomes Cancer. 2002;33:379-394.
    • (2002) Genes Chromosomes Cancer , vol.33 , pp. 379-394
    • Slovak, M.L.1    Bedell, V.2    Popplewell, L.3    Arber, D.A.4    Schoch, C.5    Slater, R.6
  • 23
    • 0025949901 scopus 로고
    • Balanced translocations involving chromosome bands 11q23 and 21q22 are highly characteristic of myelodysplasia and leukemia following therapy with cytostatic agents targeting at DNA-topoisomerase 11
    • Pedersen-Bjergaard J, Philip P. Balanced translocations involving chromosome bands 11q23 and 21q22 are highly characteristic of myelodysplasia and leukemia following therapy with cytostatic agents targeting at DNA-topoisomerase 11. Blood. 1991;78:1147-1148.
    • (1991) Blood , vol.78 , pp. 1147-1148
    • Pedersen-Bjergaard, J.1    Philip, P.2
  • 24
    • 0042925574 scopus 로고    scopus 로고
    • Acute leukemia and myelodysplasia in patients with a Philadelphia chromosome negative chronic myeloproliferative disorder treated with hydroxyurea alone or with hydroxyurea after busulphan
    • Nielsen I, Hasselbalch HC. Acute leukemia and myelodysplasia in patients with a Philadelphia chromosome negative chronic myeloproliferative disorder treated with hydroxyurea alone or with hydroxyurea after busulphan. Am J Hematol. 2003;74:26-31.
    • (2003) Am J Hematol , vol.74 , pp. 26-31
    • Nielsen, I.1    Hasselbalch, H.C.2
  • 25
    • 0036797010 scopus 로고    scopus 로고
    • Acute myeloid leukemia (AML) having evolved from essential thrombocythemia (ET): Distinctive chromosome abnormalities in patients treated with pipobroman or hydroxyurea
    • Bernasconi P, Boni M, Cavigliano PM, et al. Acute myeloid leukemia (AML) having evolved from essential thrombocythemia (ET): distinctive chromosome abnormalities in patients treated with pipobroman or hydroxyurea. Leukemia. 2002;16:2078-2083.
    • (2002) Leukemia , vol.16 , pp. 2078-2083
    • Bernasconi, P.1    Boni, M.2    Cavigliano, P.M.3
  • 26
    • 0027235886 scopus 로고
    • The cytogenetic scenario of chronic myeloid leukemia
    • Mitelman F. The cytogenetic scenario of chronic myeloid leukemia. Leak Lymphoma. 1993;11(Suppl 1):11-15.
    • (1993) Leak Lymphoma , vol.11 , Issue.SUPPL. 1 , pp. 11-15
    • Mitelman, F.1
  • 27
    • 0030032110 scopus 로고    scopus 로고
    • t(3;21)(q26;q22) with AML1 rearrangement in a de novo childhood acute monoblastic leukaemia
    • Johansson B, Fioretos T, Garwicz S, Heim S, Mitelman F. t(3;21)(q26;q22) with AML1 rearrangement in a de novo childhood acute monoblastic leukaemia. Br J Haematol. 1996;92:429-431.
    • (1996) Br J Haematol , vol.92 , pp. 429-431
    • Johansson, B.1    Fioretos, T.2    Garwicz, S.3    Heim, S.4    Mitelman, F.5
  • 28
    • 0026503441 scopus 로고
    • Activation of EVI1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26
    • Morishita K, Parganas E, William CL, et al. Activation of EVI1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26. Proc Natl Acad Sci U S A. 1992;89:3937-3941.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 3937-3941
    • Morishita, K.1    Parganas, E.2    William, C.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.