Mantle cell lymphoma with 8q24 chromosomal abnormalities: A report of 5 cases with blastoid features

Modern Pathology

Volumn 15, Issue 12, 2002, Pages 1266-1272

  Hao, Suyang ^a   Sanger, Warren ^b   Onciu, Mihaela ^a   Lai, Raymond ^a   Schlette, Ellen J ^a   Medeiros, L Jeffrey ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

8q24; Blastoid variant; C myc; Cytogenetics; Fluorescence in situ hybridization; Mantle cell lymphoma

Indexed keywords

CYCLIN D1; MYC PROTEIN;

ADULT; AGED; ARTICLE; BLAST CELL; CHROMOSOME 8Q; CHROMOSOME ABERRATION; CHROMOSOME TRANSLOCATION 11; CHROMOSOME TRANSLOCATION 14; CLINICAL ARTICLE; CYTOGENETICS; DISEASE ASSOCIATION; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE OVEREXPRESSION; HUMAN; KARYOTYPE; LEUKEMIA CELL; MALE; MANTLE CELL LYMPHOMA; ONCOGENE C MYC; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AGED; ANTIGENS, CD; ANTIGENS, CD43; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 14; CHROMOSOMES, HUMAN, PAIR 2; CHROMOSOMES, HUMAN, PAIR 8; CYCLIN D1; FEMALE; GENES, MYC; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; IN SITU HYBRIDIZATION, FLUORESCENCE; KI-67 ANTIGEN; LEUKEMIA; LYMPHOMA, MANTLE-CELL; MALE; MIDDLE AGED; SIALOGLYCOPROTEINS; TRANSLOCATION, GENETIC;

EID: 18744408734     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.MP.0000037310.82136.99     Document Type: Article

References (27)

1. Swerdlow SH, Nathwani BN, Berger F, Piris MA, Isaacson PI, Harris NL, et al. Mantle cell lymphoma. In: Jaffe ES, Harris NL, Stein H, Vardiman JW, editors. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. World Health Organization classification of tumours. Lyon, France: IARC Press; 2001. p. 168-70.
2. Lai R, Medeiros LJ. Pathologic diagnosis of mantle cell lymphoma. Clin Lymphoma 2000;1:197-206.
3. Swerdlow SH, Williams ME. From centrocytic to mantle cell lymphoma: A clinicopathologic and molecular review of 3 decades. Hum Pathol 2002;33:7-20.
4. Bodrug SE, Warner BJ, Bath ML, Lindeman GJ, Harris AW, Adams JM. Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene. EMBO J 1994;13:2124-30.
5. Lovec H, Grzeschiczek A, Kowalski M, Moroy T. Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice. EMBO J 1994;13:3487-95.
6. Bigoni R, Cuneo A, Milani R, Roberti MG, Bardi A, Rigolin GM, et al. Secondary chromosome changes in mantle cell lymphoma: Cytogenetic and fluorescence in situ hybridization studies. Leuk Lymphoma 2001;40:581-90.
7. Bentz M, Plesch A, Bullinger L, Stilgenbauer S, Ott G, Muller-Hermelink HK, et al. t(11;14)-positive mantle cell lymphomas exhibit complex karyotypes and share similarities with B-cell chronic lymphocytic leukemia. Genes Chromosomes Cancer 2000;27:285-94.
8. Cuneo A, Bigoni R, Rigolin GM, Roberti MG, Bardi A, Piva N, et al. Cytogenetic profile of lymphoma of follicle mantle lineage: Correlation with clinicobiologic features. Blood 1999;93:1372-80.
9. Espinet B, Sole F, Woessner S, Bosch F, Florensa L, Campo E, et al. Translocation (11;14)(q13;q32) and preferential involvement of chromosomes 1, 2, 9, 13, and 17 in mantle cell lymphoma. Cancer Genet Cytogenet 1999;111:92-8.
10. Johansson B, Mertens F, Mitelman F. Cytogenetic evolution patterns in non-Hodgkin's lymphoma. Blood 1995;86:3905-14.
11. Khokhar MT, Brito-Bapapulle V, Matutes E, Catovsky D. Cytogenetic abnormalities in the leukemic phase of non-Hodgkin's lymphoma. Cancer Genet Cytogenet 1995;83:18-24.
12. Wlodarska I, Pittaluga S, Hagemeijer A, De Wolf-Peeters C, Van den Berghe H. Secondary chromosome changes in mantle cell lymphoma. Haematologica 1999;84:594-9.
13. Onciu M, Schlette E, Medeiros LJ, Abruzzo LV, Keating M, Lai R. Cytogenetic findings in mantle cell lymphoma. Cases with a high level of peripheral blood involvement have a distinct pattern of abnormalities. Am J Clin Pathol 2001;116:886-92.
14. Kaneko Y, Rowley JD, Variakojis D, Haren JM, Ueshima Y, Daly K, et al. Prognostic implications of karyotype and morphology in patients with non-Hodgkin's lymphoma. Int J Cancer 1983;32:683-92.
15. Bloomfield CD, Arthur DC, Frizzera G, Levine EG, Peterson BA, Gajl-Peczalska KJ. Nonrandom chromosome abnormalities in lymphoma. Cancer Res 1983;43:2975-84.
16. Leroux D, Le Marc'Hadour F, Gressin R, Jacob MC, Keddari E, Monteil M, et al. Non-Hodgkin's lymphoma with t(11;14)(q13;q32): A subset of mantle zone/intermediate lymphocytic lymphoma? Br J Haematol 1991;77:346-53.
17. Tirier C, Zhang Y, Plendl H, Weber-Matthiesen K, Langer W, Heit W, et al. Simultaneous presence of t(11;14) and a variant Burkitt's translocation in the terminal phase of a mantle cell lymphoma. Leukemia 1996;10:346-50.
18. Au W, Horsman D, Viswanatha DS, Connors JM, Klasa RJ, Gascoyne RD. 8q24 translocations in blastic transformation of mantle cell lymphoma. Haematologica 2000;85:1225-7.
19. Vaishampayan UV, Mohamed AN, Dugan MC, Bloom RE, Palutke M. Blastic mantle cell lymphoma associated with Burkitt's-type translocation and hyperploidy. Br J Haematol 2001;115:66-8.
20. Schlette E, Bueso-Ramos C, Giles F, Glassman A, Hayes K, Medeiros LJ. Mature B-cell leukemias with more than 55% prolymphocytes. A heterogeneous group that includes an unusual variant of mantle cell lymphoma. Am J Clin Pathol 2001;115:571-81.
21. Borowitz MJ, Guenther KL, Shults KE, Stelzer GT. Immunophenotyping of acute leukemia by flow cytometric analysis: use of CD 45 and right-angle light scatter to gate on leukemia blasts in three-color analysis. Am J Clin Pathol 1993;100:534-40.
22. Mitelman F, editor. ISCN 1995: An International System for Human Cytogenetic Nomenclature 1995. Basel, Switzerland: Karger, 1995.
23. Medeiros LJ, Van Krieken J, Jaffe ES, Raffeld M. Association of bcl-1 rearrangements with lymphocytic lymphoma of intermediate differentiation. Blood 1990;76:2086-90.
24. Hernandez L, Hernandez S, Bea S, Pinyol M, Ferrer A, Bosch F, et al. c-myc mRNA expression and genomic alteration in mantle cell lymphomas and other nodal non-Hodgkin's lymphomas. Leukemia 1999;13:2087-93.
25. Martinez-Climent JA, Vizcarra E, Sanchez D, Blesa D, Marugan I, Benet I, et al. Loss of a novel tumor suppressor gene locus at chromosome 8p is associated with leukemic mantle cell lymphoma. Blood 2001;98:3479-82.
26. Boxer LM, Dang CV. Translocations involving c-myc and c-myc function. Oncogene 2001;20:5595-610.
27. Hecht JL, Aster JC. Molecular biology of Burkitt's lymphoma. J Clin Oncol 2000;18:3707-721.