Expression of the chloride channel CLC-K in human airway epithelial cells

Canadian Journal of Physiology and Pharmacology

Volumn 83, Issue 12, 2005, Pages 1123-1128

  Mummery, Jennifer L ^a,b   Killey, Jennifer ^a,c   Linsdell, Paul ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b INSTITUTE OF MOLECULAR BIOTECHNOLOGY   (Austria)

^c UNIVERSITY OF HUDDERSFIELD   (United Kingdom)

Author keywords

Airway; Chloride channel; Cystic fibrosis; Epithelial transport

Indexed keywords

CALCIUM ION; CHLORIDE CHANNEL; CHLORIDE CHANNEL K TYPE; MESSENGER RNA; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

APICAL MEMBRANE; ARTICLE; CELL PH; CHLORIDE CURRENT; CYSTIC FIBROSIS; HUMAN; HUMAN CELL; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; RESPIRATORY EPITHELIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUBMUCOSA;

BLOTTING, WESTERN; CELL LINE; CHLORIDE CHANNELS; CYTOKINES; ELECTROPHYSIOLOGY; EPITHELIAL CELLS; HUMANS; PATCH-CLAMP TECHNIQUES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

EID: 33645983340     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y05-112     Document Type: Article

References (37)

1. - currents. Neurosci. Lett. 284: 171-174. doi: 10.1016/S0304-3940(00)01021-1. PMID: 10773426.
2. Ballard, S.T., and Inglis, S.K. 2004. Liquid secretion properties of airway submucosal glands. J. Physiol. 556: 1-10. PMID: 14660706.
3. Basbaum, C.B., Jany, B., and Finkbeiner, W.E. 1990. The serous cell. Annu. Rev. physiol. 52: 97-113. doi: 10.1146/annurev.ph. 52.030190.000525. PMID: 2158772.
4. Catalán, M., Cornejo, I., Figueroa, C.D., Niemeyer, M.I., Sepúlveda, F.V., and Cid, L.P. 2002. ClC-2 in guinea-pig colon: mRNA, immunolabeling, and functional evidence for surface epithelium localization. Am. J. physiol. 283: G1004-G1013. PMID: 12223361.
5. + channels underlying anion secretion in the human airway cell line Calu-3. J. physiol. 538: 747-757. doi: 10.1113/jphysiol. 2001.013300. PMID: 11826162.
6. Cowley, E.A., and Linsdell, p. 2002b. Oxidant stress stimulates anion secretion from the human airway epithelial cell line Calu-3: implications for cystic fibrosis lung disease. J. physiol. 543: 201-209. doi: 10.1113/jphysiol.2002.022400. PMID: 12181292.
7. - channels: implications in cystic fibrosis. Clin. Exp. pharmacol. physiol. 27: 896-900. doi: 10.1046/j.1440-1681. 2000.03357.x. PMID: 11071306.
8. + secretion. Nature (London), 414: 558-561. PMID: 11734858.
9. Finkbeiner, W.E. 1999. physiology and pathology of tracheobronchial glands. Respir. physiol. 118: 77-83. doi: 10.1016/80034-5687(99)00080-8. PMID: 10647853.
10. Friedrich, T., Briederhoff, T., and Jentsch, T.J. 1999. Mutational analysis demonstrates that ClC-4 and ClC-5 directly mediate plasma membrane currents. J. Biol. Chem. 274: 896-902. doi: 10.1074/jbc.274.2.896. PMID: 9873029.
11. - channels: a newly emerging anion transport family. pflugers Arch. 443: S107-S110. doi: 10.1007/s004240100655. PMID: 11845314.
12. Gibson, R.L., Burns, J.L., and Ramsey, B.W. 2003. Pathophysiology and management of pulmonary infections in cystic fibrosis. Am. J. Respir. Crit. Care Med. 168: 918-951. doi: 10.1164/rccm.200304-505SO. PMID: 14555458.
13. Gyömörey, K., Yeger, H., Ackerley, C., Garami, E., and Bear, C.E. 2000. Expression of the chloride channel ClC-2 in the murine small intestine epithelium. Am. J. physiol. 279: C1787-C1794. PMID: 11078693.
14. - conductance. Am. J. physiol. 266: L502-L512. PMID: 7515579.
15. 2+/calmodulin-dependent protein kinase. J. Biol. Chem. 276: 20093-20100. doi: 10.1074/jbc. M009376200. PMID: 11274166.
16. Hug, M.J., Tamada, T., and Bridges, R.J. 2003. CFTR and bicarbonate secretion to epithelial cells. News Physiol. Sci. 18: 38-42. PMID: 12531931.
17. Illek, B., Tam, A.W.-K., Fischer, H., and Machen, T.E. 1999. Anion selectivity of apical membrane conductance of Calu 3 human airway epithelium. Pflugers Arch. 437: 812-822. doi: 10. 1007/s004240050850. PMID: 10370058.
18. Jeck, N., Waldegger, P., Doroszewicz, J., Seyberth, H., and Waldegger, S. 2004. A common sequence variation of the CLCNKB gene strongly activates ClC-Kb chloride channel activity. Kidney Int. 65: 190-197. doi: 10.1111/j.1523-1755. 2004.00363.x. PMID: 14675050.
19. Jentsch, T.J., Stein, V., Weinreich, F., and Zdebik, A.A. 2002. Molecular structure and physiological function of chloride channels. Physiol. Rev. 82: 503-568. PMID: 11917096.
20. Jiang, Q., and Engelhardt, J.F. 1998. Cellular heterogeneity of CFTR expression and function in the lung: implications for gene therapy of cystic fibrosis. Eur. J. Hum. Genet. 6: 12-31. doi: 10.1038/sj.ejhg.5200158. PMID: 9781011.
21. Lourdel, S., Paulais, M., Marvao, P., Nissant, A., and Teulon, J. 2003. A chloride channel at the basolateral membrane of the distal-convoluted tubule: a candidate ClC-K channel. J. Gen. Physiol. 121: 287-300. doi: 10.1085/jgp.200208737. PMID: 12668733.
22. Mohammad-Panah, R., Gyomorey, K., Rommens, J., Choudhury, M., Li, C., Wang, Y., and Bear, C.E. 2001. ClC-2 contributes to native chloride secretion by a human intestinal cell line, Caco-2. J. Biol. Chem. 276: 8306-8313. doi: 10.1074/jbc.M006764200. PMID: 11096079.
23. Mohammad-Panah, R., Ackerley, C., Rommens, J., Choudhury, M., Wang, Y., and Bear, C.E. 2002. The chloride channel ClC-4 colocalizes with cystic fibrosis transmembrane conductance regulator and may mediate chloride flux across the apical membrane of intestinal epithelia. J. Biol. Chem. 277: 566-574. PMID: 11675385.
24. Nilius, B., and Droogmans, G. 2003. Amazing chloride channels: an overview. Acta Physiol. Scand. 177: 119-147. doi: 10.1046/j.1365-201X.2003. 01060.x. PMID: 12558550.
25. Picollo, A., Liantonio, A., Didonna, M.P., Elia, L., Conte Camerino, D., and Pusch, M. 2004. Molecular determinants of differential pore blocking of kidney CLC-K chloride channels. EMBO Rep. 5: 584-589. doi: 10.1038/sj.embor. 7400169. PMID: 15167890.
26. Pilewski, J.M., and Frizzell, R.A. 1999. Role of CFTR in airway disease. Physiol. Rev. 79: S215-S255. PMID: 9922383.
27. - channel in kidney distal tubule. Biochim. Biophys. Acta, 1509: 73-85. PMID: 11118519.
28. - secretion. Am. J. Physiol. 266: L493-L501. PMID: 7515578. PMID: 9922375.
29. Sheppard, D.N., and Welsh, M.J. 1999. Structure and function of the CFTR chloride channel. Physiol. Rev. 79: S23-S45. PMID: 9922375.
30. Szkotak, A.I., Man, S.F.P., and Duszyk, M. 2003. The role of the basolateral outwardly rectifying chloride channel in human airway epithelial anion secretion. Am. J. Respir. Cell Mol. Biol. 29: 710-720. doi: 10.1165/rcmb.2003-0109OC. PMID: 12777250.
31. Uchida, S., and Sasaki, S. 2005. Function of chloride channels in the kidney. Annu. Rev. Physiol. 67: 759-778. PMID: 15709977.
32. Uyekubo, S.N., Fischer, H., Maminishkis, A., Illek, B., Miller, S.S., and Widdicombe, J.H. 1998. cAMP-dependent absorption of chloride across airway epithelium. Am. J. Physiol. 275: L1219-L1227. PMID: 9843860.
33. Verkman, A.S., Song, Y., and Thiagarajah, J.R. 2003. Role of airway surface liquid and submucosal glands in cystic fibrosis lung disease. Am. J. Physiol. 284: C2-C15. PMID: 12475759.
34. Cl,swell in rabbit nonpigmented ciliary epithelial cells involves increased ClC-3 trafficking to the plasma membrane. Biochem. Cell Biol. 82: 708-718. PMID: 15674438.
35. Waldegger, S., Jeck, N., Barth, P., Peters, M., Vitzthum, H., Wolf, K., et al. 2002. Barttin increases surface expression and changes current properties of ClC-K channels. Pflugers Arch. 444: 411-418. doi: 10.1007/s00424-002-0819-8. PMID: 12111250.
36. Wang, G.-X., Hatton, W.J., Wang, G.L., Zhong, J., Yamboliev, I., Duan, D., and Hume, J.R. 2003. Functional effects of novel anti-ClC-3 antibodies on native volume-sensitive osmolyte and anion channels in cardiac and smooth muscle cells. Am. J. Physiol. 285: H1453-H1463. PMID: 12816749.
37. Wills, N.K., and Fong, P. 2001. ClC chloride channels in epithelia: recent progress and remaining puzzles. News Physiol. Sci. 16: 161-166. PMID: 11479365.