Anion selectivity of apical membrane conductance of Calu 3 human airway epithelium

Pflugers Archiv European Journal of Physiology

Volumn 437, Issue 6, 1999, Pages 812-822

  Illek, Beate ^a,b   Tam, Albert W K ^a   Fischer, Horst ^a,b   Machen, Terry E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CHILDREN S HOSPITAL OAKLAND   (United States)

Author keywords

Anion permeation; CFTR; Cystic fibrosis; Pore size; Tight junction

Indexed keywords

ACETIC ACID; ADENOSINE TRIPHOSPHATE; BICARBONATE; BROMIDE; BUTYRIC ACID; CHLORIDE; CYCLIC AMP; FLUORIDE; FORMIC ACID; NITRATE; PHOSPHATE; PROPIONIC ACID; SODIUM CYANATE; SULFATE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANION TRANSPORT; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; MEMBRANE CONDUCTANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; RESPIRATORY EPITHELIUM;

ADENOCARCINOMA; ANIONS; BICARBONATES; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CYCLIC AMP; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ELECTRIC CONDUCTIVITY; EPITHELIAL CELLS; FATTY ACIDS; HUMANS; LUNG; LUNG NEOPLASMS; NITRATES; PHOSPHATES; PROPIONATES; THIOCYANATES; TUMOR CELLS, CULTURED;

EID: 0032950904     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050850     Document Type: Article

References (37)

1. 1. Anderson MP, Gregory RJ, Thompson S, Souza DW, Paul S, Mulligan RC, Smith AE, Welsh MJ (1991) Demonstration that CFTR is a chloride channel by alteration of its anion selectivity. Science 253:202-205
2. 2. Bell CL, Quinton PM (1992) T84 cells: anion selectivity demonstrates expression of C1 conductance affected in cystic fibrosis. Am J Physiol 262:C555-C562
3. 3. Borman J, Hamill OP, Sakmann B (1987) Mechanism of anion permeation through channels gated by glycine and gamma-aminobutyric acid in mouse cultured spinal neurones. J Physiol (Lond) 385:243-286
4. --secreting epithelial cells. Proc Natl Acad Sci USA 87:4956-4960
5. 5. Cliff WH, Schoumacher RA, Frizzell RA (1992) cAMP-activated C1 channels in CFTR-transfected cystic fibrosis pancreatic epithelial cells. Am J Physiol 262:C1154-C1160
6. 6. Eisenman G, Horn R (1983) Ionic selectivity revisited: the role of kinetic and equilibrium processes in ion permeation through channels. J Membr Biol 76:197-225
7. 7. Gray MA, Pollard CE, Harris A, Coleman L, Greenwell JR, Argent BE (1990) Anion selectivity and block of the small-conductance chloride channel on pancreatic duct cells. Am J Physiol 259:C752-C761
8. 8. Gray MA, Plant S, Argent BE (1993) cAMP-regulated whole cell chloride currents in pancreatic duct cells. Am J Physiol 264:C591-C602
9. 9. Grygorczyk R, Tabcharani JA, Hanrahan JW (1996) CFTR channels expressed in CHO cells do not have detectable ATP conductance. Am J Physiol 272:C1058-C1066
10. 10. Halm DR, Frizzell RA (1992) Anion permeation in an apical membrane chloride channel of a secretory epithelial cell. J Gen Physiol 99:339-366
11. 11. Haws C, Finkbeiner WE, Widdicombe JH, Wine JJ (1994) CFTR in Calu-3 human airway cells: channel properties and role in cAMP-activated C1 conductance. Am J Physiol 266: L692-L707
12. 12. Hipper A, Mall M, Greger R, Kunzelmann K (1995) Mutations in the putative pore-forming domain of CFTR do not change anion selectivity of the cAMP-activated C1 conductance. FEBS Lett 374:312-316
13. 2+-activated duodenal epithelial HCO3 secretion. Am J Physiol 262:G872-G878
14. 3 conductance through CFTR in human airway epithelia. Am J Physiol 272:L752-L761
15. 15. Li C, Ramjeesingh M, Bear CE (1996) Purified cystic fibrosis transmembrane conductance regulator (CFTR) does not function as an ATP channel. J Biol Chem 271:11623-11626
16. 16. Linsdell P, Tabcharani JA, Hanrahan JW (1997) Multi-ion mechanism for ion permeation and block in the cystic fibrosis transmembrane conductance regulator chloride channel. J Gen Physiol 110:365-377
17. 17. Linsdell P, Tabcharani JA, Rommens JM, Hou YX, Chang XB, Tsui LC, Riordan JR, Hanrahan JW (1997) Permeability of wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride channel to polyatomic anions. J Gen Physiol 110:355-364
18. 18. Mansoura MK, Smith SS, Choi AD, Richards NW, Strong TV, Drumm ML, Collins FS, Dawson DC (1998) Cystic fibrosis transmembrane conductance regulator (CFTR). Anion binding as a probe of the pore. Biophys J 74:1320-1332
19. 19. Ohrui T, Skach W, Thompson M, Matsumoto-Pon J, Calayag C, Widdicombe JH (1994) Radiotracer studies of cystic fibrosis transmembrane conductance regulator expressed in Xenopus oocytes. Am J Physiol 266:C1586-C1593
20. 20. Pasyk EA, Foskett JK (1997) Cystic fibrosis transmembrane conductance regulator-associated ATP and adenosine 3′-phosphate 5′-phosphosulfate channels in endoplasmic reticulum and plasma membranes. J Biol Chem 272:7746-7751
21. 21. Poulsen JH, Fischer H, Illek B, Machen TE (1994) Bicarbonate conductance and pH regulatory capability of cystic fibrosis transmembrane conductance regulator. Proc Natl Acad Sci USA 91:5340-5344
22. 22. Quinton PM (1990) Cystic fibrosis: a disease in electrolyte transport. FASEB J 4:2709-2717
23. 23. Quinton PM, Reddy MM (1989) C1 conductance and acid secretion in the human sweat duct. Ann NY Acad Sci 574: 438-446
24. 24. Reddy MM, Quinton PM, Haws C, Wine JJ, Grygorczyk R, Tabcharani JA, Hanrahan JW, Gunderson KL, Kopito RR (1996) Failure of the cystic fibrosis transmembrane conductance regulator to conduct ATP. Science 271:1876-1879
25. 25. Reisin IL, Prat AG, Abraham EH, Amara JF, Gregory RJ, Ausiello DA, Cantiello HF (1994) The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel. J Biol Chem 269:20584-20591
26. 26. Schwiebert EM, Egan ME, Hwang FH, Fulmer SB, Allen SA, Cutting GR, Guggino WB (1995) CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP. Cell 81:1063-1073
27. 27. Shen BQ, Finkbeiner WE, Wine JJ, Mrsny RJ, Widdicombe JH (1994) Calu-3: a human airway epithelial cell line that shows cAMP-dependent C1 secretion. Am J Physiol 266: L493-L501
28. 28. Sheppard DN, Rich DP, Ostedgaard LS, Gregory RJ, Smith AE, Welsh MJ (1993) Mutations in CFTR associated with mild-disease form C1-channels with altered pore properties. Nature 362:160-164
29. 29. Sheppard DN, Travis SM, Ishihara H, Welsh MJ (1996) Contribution of proline residues in the membrane-spanning domains of cystic fibrosis transmembrane conductance regulator to chloride channel function. J Biol Chem 271:14995-15001
30. 30. Song L, Hobaugh MR, Shustak C, Cheley S, Bayley H, Gouaux JE (1996) Structure of Staphylococcal α-hemolysin, a heptameric transmembrane pore. Science 274:1859-1866
31. 31. Tabcharani JA, Hanrahan JW (1993) Permeation in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel (abstract). Biophys J 64:A17
32. 32. Tabcharani JA, Rommens JM, Hou YX, Chang XB, Tsui LC, Riordan JR, Hanrahan JW (1993) Multi-ion pore behavior in the CFTR chloride channel. Nature 366:79-82
33. 33. Tabcharani JA, Linsdell P, Hanrahan JW (1997) Halide permeation in wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride channels. J Gen Physiol 110: 341-354
34. 34. Tsien RW, Hess P, McCleskey EW, Rosenberg RL (1987) Calcium channels: mechanisms of selectivity, permeation and block. Annu Rev Biophys Biol Chem 16:262-290
35. 35. Von Engelhardt W, Rechkemmer G (1992) Segmental differences of short-chain fatty acid transport across guinea pig large intestine. Exp Physiol 77:491-509
36. 36. Widdicombe JH, Welsh MJ (1980) Anion selectivity of the chloride-transport process in dog tracheal epithelium. Am J Physiol 239:C112-C117
37. 37. Wright EM, Diamond JM (1977) Anion selectivity in biological systems. Physiol Rev 57:109-156