Genetic polymorphism in T-cell epitopes of the circumsporozoite protein of Plasmodium falciparum clones and isolates from India

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 93, Issue 2, 1999, Pages 204-207

  Bhattacharya, Pramatha R ^a  

^a NATIONAL INSTITUTE OF MALARIA RESEARCH   (India)

Author keywords

Circumsporozoite protein; India; Plasmodium falciparum; Polymerase chain reaction; T helper cell epitope

Indexed keywords

EPITOPE; MALARIA VACCINE; PROTOZOAL PROTEIN;

ARTICLE; DNA SEQUENCE; GENETIC POLYMORPHISM; HELPER CELL; HUMAN; IMMUNE RESPONSE; INDIA; MALARIA; OLIGONUCLEOTIDE PROBE; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; SPOROZOITE;

PLASMODIUM FALCIPARUM;

EID: 0032927097     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0035-9203(99)90308-5     Document Type: Article

References (26)

1. Ballou, W. R., Hoffman, S. L., Sherwood, J. A., Hollingdale, M. R., Neva, F. A., Hockmeyer, W. I., Shneider, L, Wirtz, R. A., Young, J. F., Wasserman, G. F., Reeve, P., Diggs, C. L. & Chulay, J. D. (1987). Safety and efficacy of a recombinant DNA Plasmodium falciparum sporozoite vaccine. Lancet, i, 1277-1281.
2. Bhattacharya, P. R., Biswas, S. & Kabilan, L. (1997). Alleles of the Plasmodium falciparum pfmdr1 gene appear not to be associated with chloroquine resistance in India. Transactions of the Royal Society of Tropical Medicine and Hygiene, 91, 454-455.
3. Caspers, P., Gentz, R., Matile, H., Pink, J. R. & Sinigaglia, F. (1989). The circumsporozoite protein gene from NF54, a Plasmodium falciparum isolate used in malaria vaccine trials. Molecular and Biochemical Parasitology, 35, 185-190.
4. Dame, J. B., Williams, J. L., McCutchan, T. F., Weber, J. L., Wirth, R. A., Hockmeyer, W. A., Maloy, W. L., Haynes, J. D., Xcheneider, I., Roberts, D., Sanders, G. S., Reddy, E. P., Diggs, C. L. & Miller, L. H. (1984). Structure of the gene encoding the immunodominant surface antigen on the sporozoite of the human malaria parasite Plasmodium falciparum. Science, 225, 593-599.
5. De Groot, A. S., Johnson, A. H., Maloy, W. L., Quaki, I. A., Riley, E. M., Menon, A., Banks, S. M., Berzofsky, J. A. & Good, M. F. (1989). Human T cell recognition of polymorphic epitopes from malaria circumsporozoite protein. Journal of Immunology, 142, 4000-4005.
6. de la Cruz, V. F., Lal, A. A. & McCutchan, T. F. (1987). Sequence variation in putative functional domains of the circumsporozoite protein of Plasmodium falciparum: implications for vaccine development. Journal of Biological Chemistry, 262, 11935-11939.
7. de la Cruz, V. F., Maloy, W. L., Lal, A. A., Good, M. F. & McCutchan, T. F. (1988). Lack of cross-reactivity between variant T cell determinants from malaria circumsporozoite protein. Journal of Immunology, 141, 2456-2460.
8. de la Cruz, V. F., Maloy, W. L., Miller, L. H., Good, M. F. & McCutchan, T. F. (1989). The immunological significance of variation within malaria circumsporozoite protein sequences. Journal of Immunology, 142, 3568-3575.
9. Del Portillo, H. A., Nussenzweig, R. S. & Enea, V. (1987). Circumsporozoite gene of a Plasmodium falciparum strain from Thailand. Molecular and Biochemical Parasitology, 24, 289-294.
10. Doolan, D. L., Houghten, R. A. & Good, M. F. (1991). Location of human cytotoxic T cell epitopes within a polymorphic domain of the Plasmodium falciparum circumsporozoite protein. International Immunology, 3, 511-516.
11. Doolan, D. L., Saul, A. J. & Good, M. F. (1992). Geographically restricted heterogeneity of the Plasmodium falciparum circumsporozoite protein: relevance for vaccine development. Infection and Immunity, 60, 675-682.
12. Etlinger, H. M., Telix, A. M., Gillessen, D., Heimer, E. P., Just, J., Pink, J. R. L., Sinigaglia, F., Sturchler, D., Takacs, B., Trzeciak, A. & Matile, H. (1988). Assessment in humans of a synthetic peptide-based vaccine against the sporozoite stage of the human malaria parasite, Plasmodiumfalciparum. Journal of Immunology, 140, 626-633.
13. Foley, M., Ranford-Cartwright, L. C. & Babiker, H. A. (1992). Rapid and simple method for isolating malaria DNA from finger prick samples of blood. Molecular and Biochemical Parasitohgy, 53, 241-244.
14. Good, M. F., Maloy, W. L., Lunde, M. N., Margalit, H., Cornette, J. L., Smith, G. L., Moss, B., Miller, L. H. & Berzofsky, J. A. (1987). Construction of synthetic immunogen: use of new T helper epitope on malaria circumsporozoite protein. Science, 235, 1059-1062.
15. Good, M. F., Berzofsky, J. A. & Miller, L. H. (1988a). The T cell response to the malaria circumsporozoite protein: an immunological approach to vaccine development. Annual Review of Immunology, 6, 663-688.
16. Good, M. F., Pombo, D., Quakyi, I. A., Piley, E. M., Houghten, R. A., Menon, A., Alling, D. W., Berzofsky, J. A. & Miller, L. H. (1988b). Human T cell recognition of the circumsporozoite protein of Plasmodiumfalciparum. Immunodominant T cell domains map to the polymorphic regions of the molecule. Proceedings of the National Academy of Sciences of the USA, 85, 1199-1203.
17. Harrington, D. A., Clyde, D. F., Losonsky, G., Cortesia, M., Murphy, F. R., Davis, J., Baqar, A., Felix, A. M., Heimer, E. P., Gillessen, D., Nardin, E., Nussenzweig, R. S., Nussenzweig, V., Hollingdale, M. R. & Levine, M. M. (1987). Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoite. Nature, 328, 257-259.
18. Lockyer, M. J. & Schwartz, R. T. (1987). Strain variation in the circumsporozoite protein gene of Plasmodium falciparum. Molecular and Biochemical Parasitology, 22, 101-108.
19. Lockyer, M. J., Marsh, K. & Newbold, C. I. (1989). Wild isolates of Plasmodium falciparum show extensive polymorphism in T cell epitopes of the circumsporozoite protein. Molecular and Biochemical Parasitology, 37, 275-280.
20. Malik, A., Egan, J. E., Houghton, R. A., Sadoff, J. C. & Hoffmann, S. L. (1991). Human cytotoxic T lymphocytes against the Plasmodiumfalciparum circumsporozoite protein. Proceedings of the National Academy of Sciences of the USA, 88, 3300-3304.
21. Nussenzweig, V. & Nussenzweig, R. S. (1985). Circumsporozoite proteins of malaria parasites. Cell, 42, 401-403.
22. Rich, S. M., Hudson, R. R. & Ayala, F. J. (1997). Plasmodium falciparum antigenic diversity: evidence of clonal population structure. Proceedings of the National Academy of Sciences of the USA, 94, 13040-13045.
23. Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharb, S. J., Higuchi, R., Horn, G. T., Mullis, K. B. & Erlich, H. A. (1988). Primerdirected enzymatic amplification of DNA with a thermostable DNA polymerase. Science, 239, 487-491.
24. Sanger, F., Niklen, S. & Coulson, A. R. (1977). DNA sequencing with chain terminating inhibitors. Proceedings of the National Academy of Sciences of the USA, 74, 5463-5467.
25. Stout, J. A., Slaoui, M., Heppner, D. G., Momin, P., Kester, K. E., Desmons, P., Wellde, B. T., Garcon, N., Krzych, V., Marchand, M., Ballou, R. & Cohen, J. D. (1997). A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. New England Journal of Medicine, 336, 86-91.
26. Zevering, Y., Houghten, R. A., Frazer, I. H. & Good, M. F. (1990). Major population differences in T cell response to a malaria vaccine candidate. International Immunology, 2, 945-955.