Sequence diversity in the amino-terminal region of the malaria-vaccine candidate serine repeat antigen in natural Plasmodium falciparum populations

Parasitology International

Volumn 52, Issue 2, 2003, Pages 117-131

  Safitri, Indri ^a   Jalloh, Amadu ^b   Tantular, Indah S ^a   Pusarawati, Suhintam ^a   Win, Thin Thida ^b   Liu, Qing ^c   Ferreira, Marcelo U ^d   Dachlan, Yoes P ^a   Horii, Toshihiro ^e   Kawamoto, Fumihiko ^b  

^a AIRLANGGA UNIVERSITY   (Indonesia)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

^e OSAKA UNIVERSITY   (Japan)

Author keywords

Genetic diversity; Plasmodium falciparum; Serine repeat antigen; Southeast Asia

Indexed keywords

ANTIGEN; MALARIA VACCINE; SERINE;

AFRICA; ALLELE; ALLELISM; ALLOTYPE; AMINO TERMINAL SEQUENCE; ARTICLE; BRAZIL; GENE DELETION; GENE INSERTION; GENE SEQUENCE; GENETIC VARIABILITY; INDONESIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE; PARASITE ISOLATION; PLASMODIUM FALCIPARUM; POPULATION; PRIORITY JOURNAL; PROTEIN MOTIF; PUBLISHING; SOLOMON ISLANDS; THAILAND; VIET NAM; WILD TYPE;

PLASMODIUM FALCIPARUM;

EID: 0037528888     PISSN: 13835769     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5769(02)00088-0     Document Type: Article

References (36)

1. Kemp D.J., Cowman A.F., Walliker D. Genetic diversity in Plasmodium falciparum. Adv Parasitol. 29:1990;75-139.
2. Li W.B., Bzik D.J., Horii T., Inselburg J. Structure and expression of the Plasmodium falciparum SERA gene. Mol Biochem Parasitol. 33:1989;13-26.
3. Delplace P., Fortier B., Tronchin G., Dubremetz J.F., Vernes A. Localization, biosynthesis, processing and isolation of a major 126 kDa antigen of parasitophorous vacuole of Plasmodium falciparum. Mol Biochem Parasitol. 23:1987;193-201.
4. Debrabant A., Delplace P. Leupeptin alters the proteolytic processing of P126, the major parasitophorous vacuole antigen of Plasmodium falciparum. Mol Biochem Parasitol. 33:1989;151-158.
5. Knapp B., Hundt E., Nau U., Kupper H.A. Molecular cloning, genomic structure and localization of a blood-stage antigen of Plasmodium falciparum characterized by a serine stretch. Mol Biochem Parasitol. 32:1989;73-84.
6. Debrabant A., Maes P., Dalplace P., Dubremetz J.F., Tartar A., Camus D. Intramolecular maping of Plasmodium falciparum p126 proteolytic fragments by N-terminal amino acid sequencing. Mol Biochem Parasitol. 53:1992;89-96.
7. Li J., Mitamura T., Pang X.L., Fox B.A., Bzik D.J., Horii T. Differential localization of processed fragments of Plasmodium falciparum serine repeat antigen (SERA). Parasitol Int. 51:2002;343-352.
8. Fox B.A., Xing-Li P., Suzue K., Horii T., Bzik D.J. Plasmodium falciparum: an epitope within a highly conserved region of the 47-kDa amino terminal domain of the serine repeat antigen is a target of parasite-inhibitory antibodies. Exp Parasitol. 85:1997;121-134.
9. Fox B.A., Horii T., Bzik D.J. Plasmodium falciparum: Fine-mapping of an epitope of the serine repeat antigen that is a target of parasite-inhibitory antibodies. Exp Parasitol. 101:2002;69-72.
10. Perrin L.H., Merkli B., Loche M., Chizzolini C., Smart J., Richle R. Antimalarial immunity in Saimiri monkeys. Immunization with surface components of asexual blood stages. J Exp Med. 160:1984;441-451.
11. Inselburg J., Bzik D.J., Li W.B., et al. Protective immunity induced in Aotus monkeys by recombinant SERA proteins of Plasmodium falciparum. Infect Immunol. 59:1991;1247-1250.
12. Suzue K., Ito M., Matsumoto Y., Tanioka Y., Horii T. Protective immunity induced in squirrel monkeys with recombinant serine repeat antigen (SERA) of Plasmodium falciparum. Parasitol Int. 46:1997;17-25.
13. Sugiyama T., Suzue K., Okamoto M., Inselburg J., Tai K., Horii T. Production of recombinant SERA proteins of Plasmodium falciparum in E. coli by using synthetic genes. Vaccine. 14:1996;1069-1076.
14. Okech B.A., Nalunkuma A., Okello D., et al. Natural human IgG subclass responses to Plasmodium falciparum serine repeat antigen (SERA) in Uganda. Am J Trop Med Hyg. 65:2001;912-917.
15. Aoki S., Li J., Itagaki S., Okech B.A., Egwang T.G., Matsuoka H., Nirianne M.Q., Mitamura T., Horii T. SERA (SERA5) is predominantly expressed among the SERA multigene family of Plasmodium falciparum and the acquired antibody titers correlate with serum inhibition of the parasite growth. J Biol Chem. 277:2002;47533-47540.
16. Miller S.K., Good R., Drew D.R., Delorenzi M., Sanders P.R., Hodder A.N., Speed T.P., Cowman A.F., de Koning-Ward T.F., Crabb B.S. A subset of Plasmodium falciparum SERA genes are expressed and appear to play an important role in the erythrocytic cycle. J Biol Chem. 277:2002;47524-47532.
17. Higgins D.G., McConnell D.J., Sharp P.M. Malarial proteinase? Nature. 340:1989;604.
18. Horii T., Bzik D.J., Inselburg J. Characterization of antigen-expressing Plasmodium falciparum cDNA clones that are reactive with parasite inhibitory antibodies. Mol Biochem Parasitol. 30:1988;9-18.
19. Bzik D.J., Li W.B., Horii T., Inselburg J. Amino acid sequence of the serine repeat antigen (SERA) of Plasmodium falciparum determined from cloned cDNA. Mol Biochem Parasitol. 30:1988;279-288.
20. Knapp B., Nau U., Hundt E., Kupper H.A. A new blood stage antigen of Plasmodium falciparum highly homologous to the serine-stretch protein SERP. Mol Biochem Parasitol. 44:1991;1-14.
21. Fox B.A., Bzik D.J. Analysis of stage specific transcripts of the Plasmodium falciparum serine repeat antigen (SERA) gene and transcription from the SERA locus. Mol Biochem Parasitol. 68:1994;133-144.
22. Morimatsu K., Morikawa T., Tanabe K., Bzik D.J., Horii T. Sequence diversity in the amino terminal 47 kDa fragment of the Plasmodium falciparum serine repeat antigen. Mol Biochem Parasitol. 86:1997;249-254.
23. Liu Q., Ferreira M.U., Ndawi B.T., et al. Sequence diversity of serine repeat antigen gene exon II of Plasmodium falciparum in worldwide collected wild isolates. Southeast Asian J Trop Med Public Health. 31:2000;808-817.
24. Kawamoto F. Rapid diagnosis of malaria by fluorescence microscopy with light microscope and interference filter. Lancet. 337:1991;200-202.
25. Kawamoto F., Win T.T., Mizuno S., et al. Unusual Plasmodium malariae-like parasites in Southeast Asia. J Parasitol. 88:2002;350-357.
26. Win T.T., Lin K., Mizuno S., et al. Wide distribution of Plasmodium ovale in Myanmar. Trop Med Int Health. 7:2002;231-239.
27. Zhou M., Liu Q., Wongsrichanalai C., et al. High prevalence of Plasmodium malariae and P. ovale in malaria patients along the Thai-Myanmar border, as revealed by acridine orange staining and PCR-based diagnoses. Trop Med Int Health. 3:1998;304-312.
28. Wooden J., Kyes S., Sibley C.H. PCR and strain identification in Plasmodium falciparum. Parasitol Today. 9:1993;303-305.
29. Rich S.M., Hudson R.R., Ayala F.J. Plasmodium falciparum antigenic diversity: evidence of clonal population structure. Proc Natl Acad Sci USA. 94:1997;13040-13045.
30. Rich S.M., Ferreira M.U., Ayala F.J. The origin of antigenic diversity in Plasmodium falciparum. Parasitol Today. 16:2000;390-396.
31. Belperron A.A., Felquate D., Fox B.A., Horii T., Bzik D.J. Immune responses induced by gene gun or intramuscular injection of DNA vaccines that express immunogenic regions of the serine repeat antigen from Plasmodium falciparum. Infect Immunol. 67:1999;5163-5169.
32. Conway D.J., Cavanagh D.R., Tanabe K., et al. A principal target of human immunity to malaria identified by molecular population genetic and immunological analyses. Nat Med. 6:2000;689-692.
33. Conway D.J. Natural selection on polymorphic malaria antigens and the search for a vaccine. Parasitol Today. 13:1997;26-29.
34. Polley S.D., Conway D.J. Strong diversifying selection on domains of the Plasmodium falciparum apical membrane antigen 1 gene. Genetics. 158:2001;1505-1512.
35. Ferreira MU, Ribeiro WL, Tonon AP, Kawamoto F, Rich SM. Sequence diversity and evolution of the malaria vaccine candidate merozoite surface protein-1 (MSP-1) of Plasmodium falciparum. Gene, in press.
36. Hoffmann E.H.E., Silveira L.A., Tonhosolo R., et al. Geographical patterns of allelic diversity in the Plasmodium falciparum malaria-vaccine candidate, merozoite surface protein-2. Ann Trop Med Parasitol. 95:2001;117-132.