Generation and characterization of malaria-specific human CD8+ lymphocyte clones: Effect of natural polymorphism on T cell recognition and endogenous cognate antigen presentation by liver cells

European Journal of Immunology

Volumn 30, Issue 11, 2000, Pages 3079-3088

  Bonelo, Anilza ^a,b   Valmori, Danila ^c   Triponez, Fredéric ^d   Tiercy, Jean Marie ^d   Mentha, Gilles ^d   Oberholzer, José ^d   Champagne, Patrick ^e   Romero, Jackie F ^a   Esposito, Fulvio ^f   Nebié, Issa ^g   Barbey, Catherine ^h   Romero, Pedro ^c   Herrera, Socrates ^b   Corradin, Giampietro ^a   López, José Alejandro ^a,i  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSIDAD DEL VALLE   (Colombia)

^c LUDWIG INSTITUTE FOR CANCER RESEARCH   (Switzerland)

^d GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^e CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^f UNIVERSITY OF CAMERINO   (Italy)

^g Burkina Faso   (Burkina Faso)

^h LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

ⁱ MATER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Hepatocyte; Human CTL clone; Malaria; Polymorphism; TCR recognition

Indexed keywords

CD8 ANTIGEN; GAMMA INTERFERON; HLA A2 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN;

ANIMAL CELL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; LIVER CELL; MALARIA; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; SPOROZOITE; T LYMPHOCYTE SUBPOPULATION; VACCINIA VIRUS;

ADULT; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, PROTOZOAN; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CYTOTOXICITY, IMMUNOLOGIC; HUMANS; LIVER; MALARIA; MICE; PLASMODIUM FALCIPARUM; POLYMORPHISM, GENETIC; RECEPTORS, ANTIGEN, T-CELL;

EID: 0033730037     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200011)30:11<3079::AID-IMMU3079>3.0.CO;2-7     Document Type: Article

References (46)

1. Protective immunity produced by the injection of X-irradiated sporozoites of Plasmodium berghei
2. Immunity to falciparum and vivax malaria induced by irradiated sporozoites: A review of the University of Maryland studies, 1971-75
3. Malaria vaccine: Immunization of mice with a synthetic T cell helper epitope alone leads to protective immunity
4. Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein
5. + T cell- and IFN-gamma-dependent elimination of infected hepatocytes
6. Induction of protective CTL responses against the Plasmodium yoelii circumsporozoite protein by immunization with peptides
7. Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine
8. + T cells to sporozolte-induced protection against malaria
9. + T cells (cytotoxic/suppressors) are required for protection in mice immunized with malaria sporozoites
10. Isolation and characterization of protective cytolytic T cells in a rodent malaria model system
11. + T lymphocytes from mice immunized with a synthetic malaria peptide
12. + T-cell protective immunity induced by immunization with Plasmodium berghei CS protein-derived synthetic peptides: Evidence that localization of peptide-specific CTLs is crucial for protection against malaria
13. Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria
14. + T cell clones correlates with their levels of expression of adhesion molecules
15. Degenerate cytotoxic T cell epitopes from P. falciparum restricted by multiple HLA-A and HLA-B supertype alleles
16. Attacking the infected hepatocyte
17. Cytotoxic T cells recognize a peptide from the circumsporozoite protein on malaria-infected hepatocytes
18. Hybridoma produces protective antibodies directed against the sporozoite stage of malaria parasite
19. Structure of the gene encoding the immunodominant surface antigen on the sporozoite of the human malaria parasite Plasmodium falciparum
20. Wild isolates of Plasmodium falciparum show extensive polymorphism in T cell epitopes of the circumsporozoite protein
21. Localization of HLA-A2.1 -restricted T cell epitopes in the circumsporozoite protein of Plasmodium falciparum
22. + CTL epitope in naturally exposed Kenyan adults
23. Identification of conserved antigenic components for a cytotoxic T lymphocyte-inducing vaccine against malaria
24. Cytotoxic T lymphocytes to Plasmodium falciparum epitopes in an area of intense and perennial transmission in Tanzania
25. + T-lymphocyte responses to malaria: Identification of new Plasmodium falciparum epitopes by IFN-γ ELISPOT
26. Diversity of the fine specificity displayed by HLA-A*0201-restricted CTL specific for the immunodominant Melan-A/MART-1 antigenic peptide
27. Immunogenicity of peptides bound to MHC class I molecules depends on the MHC-peptide complex stability
28. + T cells in primary and secondary influenza pneumonia
29. + T cells during the primary immune response to Epstein-Barr virus in vivo
30. + T cells in individuals receiving highly active antiretroviral therapy (HAART)
31. High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals
32. Maintenance of protective immunity against malaria by persistent hepatic parasites derived from irradiated sporozoites
33. + T cells and antibodies required for immunity to malaria sporozoites
34. Co-localization of inducible-nitric oxide synthase and Plasmodium berghei in hepatocytes from rats immunized with irradiated sporozoltes
35. + T cells surrounding Plasmodium berghei-infected hepatocytes
36. Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells
37. Association of malaria parasite population structure, HLA, and immunological antagonism
38. Induction in transgenic mice of HLA-A2.1-restricted cytotoxic T cells specific for a peptide sequence from a mutated p21ras protein
39. Phenotypic analysts of antigen-specific T lymphocytes
40. HLA-A2-peptide complexes: Refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides
41. Enhanced generation of specific tumor-reactive CTL in vitro by selected Melan-A/MART-1 immunodominant peptide analogues
42. Reconstitution of the T-cell compartment after bone marrow transplantation: Restoration of the repertoire by thymic emigrants
43. Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex
44. Complete development of hepatic stages of Plasmodium falciparum in vitro
45. Glucokinase and cytosolic phosphoenolpyruvate carboxykinase (GTP) in the human liver. Regulation of gene expression in curtured hepatocytes
46. Reverse ELISPOT assay for clonal analysis of cytokine production. I. Enumeration of gamma-interferon-secreting cells